AP2006003517A0 - Hiv replication purine derivatives. - Google Patents

Hiv replication purine derivatives.

Info

Publication number: AP2006003517A0
Authority: AP; ARIPO
Prior art keywords: hiv replication; purine derivatives; purine; derivatives; hiv
Prior art date: 2003-09-25

Application number

AP2006003517A

Other languages

English (en)

Inventor

Lucien Maria Henricus Koymans

Frederik Frans Desire Daeyaert

Jan Heeres

Original Assignee

Janssen Pharmaceutica Nv

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2003-09-25

Filing date

2004-09-21

Publication date

2006-02-28

2004-09-21 Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv

2006-02-28 Publication of AP2006003517A0 publication Critical patent/AP2006003517A0/xx

Links

229940083251 peripheral vasodilators purine derivative Drugs 0.000 title 1
125000000561 purinyl group Chemical class N1=C(N=C2N=CNC2=C1)* 0.000 title 1
230000010076 replication Effects 0.000 title 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
- A61K31/52—Purines, e.g. adenine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
- C07D473/16—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two nitrogen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
- C07D473/18—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 one oxygen and one nitrogen atom, e.g. guanine

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Virology (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
AIDS & HIV (AREA)
Tropical Medicine & Parasitology (AREA)
Molecular Biology (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

AP2006003517A 2003-09-25 2004-09-21 Hiv replication purine derivatives. AP2006003517A0 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
EP0350659		2003-09-25
PCT/EP2004/052262 WO2005028479A2 (en)	2003-09-25	2004-09-21	Hiv replication inhibiting purine derivatives

Publications (1)

Publication Number	Publication Date
AP2006003517A0 true AP2006003517A0 (en)	2006-02-28

Family

ID=34354400

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AP2006003517A AP2006003517A0 (en)	2003-09-25	2004-09-21	Hiv replication purine derivatives.

Country Status (19)

Country	Link
US (1)	US8026245B2 (de)
EP (1)	EP1668011B1 (de)
JP (1)	JP5506751B2 (de)
KR (1)	KR20060121878A (de)
CN (1)	CN100475815C (de)
AP (1)	AP2006003517A0 (de)
AT (1)	ATE500254T1 (de)
AU (1)	AU2004274185B2 (de)
BR (1)	BRPI0414791A (de)
CA (1)	CA2535313C (de)
DE (1)	DE602004031641D1 (de)
EA (1)	EA009734B1 (de)
ES (1)	ES2361835T3 (de)
IL (1)	IL174467A0 (de)
MX (1)	MXPA06002069A (de)
NO (1)	NO20061788L (de)
TW (1)	TW200518758A (de)
WO (1)	WO2005028479A2 (de)
ZA (1)	ZA200602440B (de)

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CA2642229C (en)	2006-02-24	2015-05-12	Rigel Pharmaceuticals, Inc.	Compositions and methods for inhibition of the jak pathway
EP2132211A4 (de) *	2006-11-09	2011-12-07	Ardea Biosciences Inc	4-cyanphenylamino-substituierte bizyklische und heterozyklische verbindungen als hiv-hemmer
AU2008210455A1 (en)	2007-01-31	2008-08-07	Vertex Pharmaceuticals Incorporated	2-aminopyridine derivatives useful as kinase inhibitors
JP5099794B2 (ja)	2007-11-27	2012-12-19	アルデアバイオサイエンシーズインク．	新規化合物、組成物、及び使用方法
ES2389752T3 (es)	2007-12-14	2012-10-31	Ardea Biosciences, Inc.	Inhibidores de la transcriptasa inversa
US8569337B2 (en)	2008-07-23	2013-10-29	Vertex Pharmaceuticals Incorporated	Tri-cyclic pyrazolopyridine kinase inhibitors
ES2402087T3 (es)	2008-07-23	2013-04-26	Vertex Pharmaceuticals Incorporated	Inhibidores de la pirazolopiridina quinasa
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FR2962437B1 (fr)	2010-07-06	2012-08-17	Sanofi Aventis	Derives d'imidazopyridine, leur procede de preparation et leur application en therapeutique
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WO2020084142A1 (en) *	2018-10-25	2020-04-30	Minakem	Process for the preparation of rilpivirine
CN110526873B (zh) *	2019-08-15	2022-09-16	复旦大学	氰乙烯基取代的苯并二芳基嘧啶类化合物及其制备方法和用途
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2004
- 2004-09-21 DE DE602004031641T patent/DE602004031641D1/de not_active Expired - Lifetime
- 2004-09-21 EP EP04766834A patent/EP1668011B1/de not_active Expired - Lifetime
- 2004-09-21 AP AP2006003517A patent/AP2006003517A0/xx unknown
- 2004-09-21 US US10/573,364 patent/US8026245B2/en not_active Expired - Fee Related
- 2004-09-21 EA EA200600648A patent/EA009734B1/ru not_active IP Right Cessation
- 2004-09-21 MX MXPA06002069A patent/MXPA06002069A/es active IP Right Grant
- 2004-09-21 KR KR1020067005328A patent/KR20060121878A/ko not_active Withdrawn
- 2004-09-21 CA CA2535313A patent/CA2535313C/en not_active Expired - Fee Related
- 2004-09-21 WO PCT/EP2004/052262 patent/WO2005028479A2/en not_active Ceased
- 2004-09-21 BR BRPI0414791-0A patent/BRPI0414791A/pt not_active Application Discontinuation
- 2004-09-21 AU AU2004274185A patent/AU2004274185B2/en not_active Ceased
- 2004-09-21 ES ES04766834T patent/ES2361835T3/es not_active Expired - Lifetime
- 2004-09-21 CN CNB2004800278401A patent/CN100475815C/zh not_active Expired - Fee Related
- 2004-09-21 AT AT04766834T patent/ATE500254T1/de not_active IP Right Cessation
- 2004-09-24 TW TW093128936A patent/TW200518758A/zh unknown
2006
- 2006-03-21 IL IL174467A patent/IL174467A0/en active IP Right Grant
- 2006-03-24 ZA ZA200602440A patent/ZA200602440B/en unknown
- 2006-04-24 NO NO20061788A patent/NO20061788L/no not_active Application Discontinuation
2011
- 2011-08-01 JP JP2011168572A patent/JP5506751B2/ja not_active Expired - Fee Related

Also Published As

Publication number	Publication date
EA009734B1 (ru)	2008-02-28
DE602004031641D1 (de)	2011-04-14
JP5506751B2 (ja)	2014-05-28
ES2361835T3 (es)	2011-06-22
JP2012006945A (ja)	2012-01-12
EA200600648A1 (ru)	2006-08-25
IL174467A0 (en)	2006-08-01
US8026245B2 (en)	2011-09-27
BRPI0414791A (pt)	2006-11-21
ATE500254T1 (de)	2011-03-15
AU2004274185B2 (en)	2009-12-10
NO20061788L (no)	2006-04-24
CN1856496A (zh)	2006-11-01
US20060293330A1 (en)	2006-12-28
CA2535313A1 (en)	2005-03-31
KR20060121878A (ko)	2006-11-29
JP4825672B2 (ja)	2011-11-30
CN100475815C (zh)	2009-04-08
EP1668011A2 (de)	2006-06-14
EP1668011B1 (de)	2011-03-02
CA2535313C (en)	2012-07-17
AU2004274185A1 (en)	2005-03-31
TW200518758A (en)	2005-06-16
WO2005028479A2 (en)	2005-03-31
JP2007506707A (ja)	2007-03-22
MXPA06002069A (es)	2006-05-19
ZA200602440B (en)	2007-09-26
WO2005028479A3 (en)	2005-06-16

Publication	Publication Date	Title
AP2006003517A0 (en)	2006-02-28	Hiv replication purine derivatives.
MXPA03002269A (es)	2003-06-06	Derivados de purina.
IL169596A (en)	2017-02-28	Triazines inhibit HIV replication
MXPA03001775A (es)	2003-06-04	Derivados de nucleosidos.
AP2004002993A0 (en)	2004-03-31	HIV replication inhibiting pyrimidines.
EG23424A (en)	2005-07-12	Fungicidal azo-carboxamide derivatives.
AP2265A (en)	2011-08-01	Reduced-exposure tobacco products.
MXPA03007349A (es)	2003-12-04	Derivados de xantina, su preparacion y su empleo como medicamentos.
EP2223921B8 (de)	2013-02-20	2-Thiophen-2-yl-oxazol-, 2-Thiophen-2-yl-thiazol- und 2-Thiophen-2-yl-1H-imidazol-Derivate als antivirale Wirkstoffe
PT1673352E (pt)	2009-06-19	Pirimidinas sulfoximino-substituídas como inibidores das cdk e/ou dos vegf, a sua produção e a sua utilização como medicamentos
ZA200305498B (en)	2004-05-07	Xanthine derivative, production and use thereof as a medicament.
EP1897882A4 (de)	2009-12-23	N2-chinolyl- oder -isochinolylsubstituierte purinderivate, deren herstellung und deren verwendung
AP2005003353A0 (en)	2005-09-30	Diazepinoindole derivatives as kinase inhibitors.
ZA200501557B (en)	2005-09-08	4-Pyrrolidino-phenyl-benzyl ether derivatives.
SI1608654T1 (sl)	2010-04-30	8-subst.-6,7,8,9-tetrahidropirimido(1,2-a)pirimidin-4-onski derivati
AP2006003481A0 (en)	2006-02-28	2-Substituted phenyl-5, 7- dihydrocarbyl-3, 7- di hydropyrrolo Ä2,3-dÜ pyrimidin-4- one derivatives,the preparation and the pharmaceutical use thereo f.
ITCZ20030016A1 (it)	2005-05-14	Portaimpronte modulare o componibile.
IL180894A0 (en)	2007-07-04	1-??-halo-2,2-difluoro-2-deoxy-d-ribofuranose derivatives and processes for the preparation thereof
IL169318A0 (en)	2009-02-11	Pyrimidines, methods for the production thereof, and use thereof
ZA200408787B (en)	2005-10-20	Pharmaceutical combination.
LU91022B1 (en)	2004-11-10	Sektionaltor.
ZA200402741B (en)	2004-10-26	Supplements for HIV infected persons.
GB2434893B8 (en)	2008-04-16	Triangular Asynchronous Replication.
GB0327133D0 (en)	2003-12-24	Viral replication
GB0327270D0 (en)	2003-12-24	Viral replication