AP2009004880A0 - Spiroketone acetyl-COA carboxylase inhibitors - Google Patents
Spiroketone acetyl-COA carboxylase inhibitorsInfo
- Publication number
- AP2009004880A0 AP2009004880A0 AP2009004880A AP2009004880A AP2009004880A0 AP 2009004880 A0 AP2009004880 A0 AP 2009004880A0 AP 2009004880 A AP2009004880 A AP 2009004880A AP 2009004880 A AP2009004880 A AP 2009004880A AP 2009004880 A0 AP2009004880 A0 AP 2009004880A0
- Authority
- AP
- ARIPO
- Prior art keywords
- spiroketone
- acetyl
- coa carboxylase
- carboxylase inhibitors
- inhibitors
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/10—Spiro-condensed systems
- C07D491/107—Spiro-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
- A61K31/39—Heterocyclic compounds having sulfur as a ring hetero atom having oxygen in the same ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/10—Spiro-condensed systems
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Diabetes (AREA)
- Cardiology (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Heart & Thoracic Surgery (AREA)
- Endocrinology (AREA)
- Urology & Nephrology (AREA)
- Emergency Medicine (AREA)
- Hospice & Palliative Care (AREA)
- Vascular Medicine (AREA)
- Child & Adolescent Psychology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US86177906P | 2006-11-29 | 2006-11-29 | |
| PCT/IB2007/003639 WO2008065508A1 (fr) | 2006-11-29 | 2007-11-16 | Inhibiteurs de la spirocétoneacétyl-coa carboxylase |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AP2009004880A0 true AP2009004880A0 (en) | 2009-06-30 |
Family
ID=39126209
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AP2009004880A AP2009004880A0 (en) | 2006-11-29 | 2007-11-16 | Spiroketone acetyl-COA carboxylase inhibitors |
Country Status (23)
| Country | Link |
|---|---|
| US (1) | US20090270435A1 (fr) |
| EP (1) | EP2097420B1 (fr) |
| JP (1) | JP2010511035A (fr) |
| KR (1) | KR20090083956A (fr) |
| CN (1) | CN101541809A (fr) |
| AP (1) | AP2009004880A0 (fr) |
| AT (1) | ATE552262T1 (fr) |
| AU (1) | AU2007326950B2 (fr) |
| BR (1) | BRPI0721053A2 (fr) |
| CA (1) | CA2670422C (fr) |
| CO (1) | CO6180424A2 (fr) |
| CR (1) | CR10831A (fr) |
| EA (1) | EA200900613A1 (fr) |
| EC (1) | ECSP099371A (fr) |
| IL (1) | IL198779A0 (fr) |
| MA (1) | MA30932B1 (fr) |
| MX (1) | MX2009005604A (fr) |
| NO (1) | NO20091889L (fr) |
| RS (1) | RS20090249A (fr) |
| SV (1) | SV2009003281A (fr) |
| TN (1) | TN2009000204A1 (fr) |
| WO (1) | WO2008065508A1 (fr) |
| ZA (1) | ZA200903268B (fr) |
Families Citing this family (73)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PE20081559A1 (es) | 2007-01-12 | 2008-11-20 | Merck & Co Inc | DERIVADOS DE ESPIROCROMANONA SUSTITUIDOS COMO INHIBIDORES DE ACETIL CoA CARBOXILASA |
| AU2008205642B2 (en) * | 2007-01-12 | 2013-06-06 | Msd K.K. | Spirochromanon derivatives |
| CN100550853C (zh) * | 2007-01-25 | 2009-10-14 | 华为技术有限公司 | 一种基于输出队列的流控实现方法及装置 |
| DE102007028521A1 (de) * | 2007-06-21 | 2008-12-24 | Merck Patent Gmbh | Indazolamidderivate |
| US8318762B2 (en) | 2008-05-28 | 2012-11-27 | Pfizer Inc. | Pyrazolospiroketone acetyl-CoA carboxylase inhibitors |
| WO2009144555A1 (fr) * | 2008-05-28 | 2009-12-03 | Pfizer Inc. | Inhibiteurs de la pyrazolospirocétone acétyl-coa carboxylase |
| JP5501256B2 (ja) * | 2008-07-04 | 2014-05-21 | Ｍｓｄ株式会社 | 新規スピロクロマノンカルボン酸 |
| EP2310015A4 (fr) | 2008-07-14 | 2011-10-26 | Cropsolution Inc | Modulateurs de l acétyl-coenzyme a carboxylase et procédés d utilisation associés |
| DE102008038222A1 (de) | 2008-08-18 | 2010-02-25 | Merck Patent Gmbh | Indazol-5-carbonsäurehydrazid-derivate |
| EP2184276A1 (fr) | 2008-11-07 | 2010-05-12 | Universite Paul Cezanne Aix-Marseille Iii | Procédé de préparation de nouvelles 1H-benzo(d) imidazol-2(3h)-ones substituées, de nouveaux intermédiaires et leur utilisation en tant qu'inhibiteurs de bace 1 |
| US20120225900A1 (en) * | 2009-11-10 | 2012-09-06 | Pfizer Inc. | N2-pyrazolospiroketone acetyl-coa carboxylase inhibitors |
| CN102695708B (zh) * | 2009-11-10 | 2014-10-15 | 辉瑞大药厂 | N1-吡唑并螺酮乙酰辅酶a羧化酶抑制剂 |
| SG183812A1 (en) | 2010-03-19 | 2012-10-30 | Pfizer | 2,3 dihydro-1h-inden-1-yl- 2,7-diazaspiro [3.5] nonane derivatives and their use as antagonists or inverse agonists of the ghrelin receptor |
| US8598164B2 (en) | 2010-05-06 | 2013-12-03 | Vertex Pharmaceuticals Incorporated | Heterocyclic chromene-spirocyclic piperidine amides as modulators of ion channels |
| EP2582709B1 (fr) | 2010-06-18 | 2018-01-24 | Sanofi | Dérivés d'azolopyridin-3-one en tant qu'inhibiteurs de lipases et de phospholipases |
| RS55224B1 (sr) | 2010-09-30 | 2017-02-28 | Pfizer | N1-pirazolospiroketon acetil-coa karboksilaza inhibitori |
| PT2632925E (pt) * | 2010-10-29 | 2015-09-01 | Pfizer | Inibidores de n1/n2-lactama da acetil-coa carboxilase |
| TWI520964B (zh) | 2011-02-02 | 2016-02-11 | 維泰克斯製藥公司 | 作為離子通道調節劑之吡咯并吡－螺環哌啶醯胺 |
| AU2012217616B2 (en) * | 2011-02-18 | 2017-03-02 | Vertex Pharmaceuticals Incorporated | Chroman - spirocyclic piperidine amides as modulators of ion channels |
| US8828996B2 (en) | 2011-03-14 | 2014-09-09 | Vertex Pharmaceuticals Incorporated | Morpholine-spirocyclic piperidine amides as modulators of ion channels |
| RS54526B1 (sr) | 2011-04-22 | 2016-06-30 | Pfizer Inc. | Upotreba derivata pirazolospiroketona kao inhibitora acetil-coa karboksilaze |
| ES2648308T3 (es) | 2011-07-08 | 2017-12-29 | Bayer Intellectual Property Gmbh | Procedimiento para la preparación de 2-amino-5-ciano-N,3-dimetilbenzamida |
| CA2841757A1 (fr) | 2011-07-15 | 2013-01-24 | Etzer Darout | Modulateurs de gpr 119 |
| JP5647379B2 (ja) | 2011-07-22 | 2014-12-24 | ファイザー・インク | キノリニルグルカゴン受容体モジュレーター |
| MY166866A (en) | 2011-08-18 | 2018-07-24 | Nippon Shinyaku Co Ltd | Heterocyclic derivative and pharmaceutical drug |
| WO2013030713A1 (fr) | 2011-08-31 | 2013-03-07 | Pfizer Inc. | Hexahydropyrano[3,4-d][1,3]thiazine-2-amines |
| SG11201401531RA (en) | 2011-11-11 | 2014-07-30 | Pfizer | 2-thiopyrimidinones |
| PE20142164A1 (es) | 2012-04-06 | 2014-12-27 | Pfizer | Inhibidores de diacilglicerol aciltransferasa 2 |
| US8889730B2 (en) | 2012-04-10 | 2014-11-18 | Pfizer Inc. | Indole and indazole compounds that activate AMPK |
| JP6110937B2 (ja) | 2012-05-04 | 2017-04-05 | ファイザー・インク | ＡＰＰ、ＢＡＣＥ１、およびＢＡＣＥ２の阻害剤としての複素環式置換ヘキサヒドロピラノ［３，４−ｄ］［１，３］チアジン−２−アミン化合物 |
| CA2882389A1 (fr) | 2012-09-20 | 2014-03-27 | Pfizer Inc. | Composes d'hexahydropyrano[3,4-d][1,3]thiazine-2-amine alkyl-substitues |
| JP2016502978A (ja) | 2012-12-11 | 2016-02-01 | ファイザー・インク | ＢＡＣＥ１の阻害剤としてのヘキサヒドロピラノ［３，４−ｄ］［１，３］チアジン−２−アミン化合物 |
| CA2893333C (fr) | 2012-12-19 | 2017-10-24 | Pfizer Inc. | Composes hexahydropyrano[3,4-d][1,3]thiazin-2-amine substitues carbocycliques et heterocycliques |
| CA2897678A1 (fr) | 2013-02-13 | 2014-08-21 | Pfizer Inc. | Composes hexahydropyrano [3,4-d][1,3] thiazin-2-amine substitues par un heteroaryle |
| US9233981B1 (en) | 2013-02-15 | 2016-01-12 | Pfizer Inc. | Substituted phenyl hexahydropyrano[3,4-d][1,3]thiazin-2-amine compounds |
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| BR112017026191B1 (pt) | 2015-06-17 | 2023-10-10 | Pfizer Inc | Compostos tricíclicos inibidores de fosfodiesterase, sua composição farmacêutica e uso dos mesmos |
| WO2016203335A1 (fr) | 2015-06-18 | 2016-12-22 | Pfizer Inc. | Nouvelles pyrido [2,3-b] pyrazinones utilisées en tant qu'inhibiteurs de bromodomaines de la famille bet |
| JP2018527337A (ja) | 2015-08-13 | 2018-09-20 | ファイザー・インク | 二環式縮合ヘテロアリールまたはアリール化合物 |
| EP3858825A1 (fr) | 2015-08-27 | 2021-08-04 | Pfizer Inc. | Composés hétéroaryles bicycliques condensés en tant que modulateurs d'irak 4 |
| WO2017037567A1 (fr) | 2015-09-03 | 2017-03-09 | Pfizer Inc. | Régulateurs de la frataxine |
| WO2017051294A1 (fr) | 2015-09-24 | 2017-03-30 | Pfizer Inc. | N-[2-(3-amino-2,5-diméthyl-1,1-dioxido-5,6-dihydro-2h-1,2,4-thiadiazin-5-yl)-1,3-thiazol-4-yl] amides utiles comme inhibiteurs de bace |
| AU2016325665A1 (en) | 2015-09-24 | 2018-03-08 | Pfizer Inc. | N-[2-(2-amino-6,6-disubstituted-4, 4a, 5, 6-tetrahydropyrano [3,4-d][1,3] thiazin-8a (8h)-yl) -1, 3-thiazol-4-yl] amides |
| JP2018531924A (ja) | 2015-09-24 | 2018-11-01 | ファイザー・インク | テトラヒドロピラノ［３，４−ｄ］［１，３］オキサジン誘導体、およびｂａｃｅ阻害剤としてのその使用 |
| TN2018000198A1 (en) | 2015-12-29 | 2019-10-04 | Pfizer | Substituted 3-azabicyclo[3.1.0]hexanes as ketohexokinase inhibitors |
| BR112019000589A2 (pt) | 2016-07-14 | 2019-04-24 | Pfizer Inc. | pirimidina carboxamidas como inibidores da enzima vanina-1 |
| AR109179A1 (es) | 2016-08-19 | 2018-11-07 | Pfizer | Inhibidores de diacilglicerol aciltransferasa 2 |
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| CN108658938B (zh) * | 2018-06-15 | 2021-03-23 | 上海现代制药股份有限公司 | 一种甲磺酸达比加群酯工艺杂质的合成方法 |
| CN108774242B (zh) * | 2018-08-22 | 2020-10-27 | 牡丹江医学院 | 一种防治冠心病的药物及其制备方法 |
| AU2019329884B2 (en) | 2018-08-31 | 2022-01-27 | Pfizer Inc. | Combinations for treatment of NASH/NAFLD and related diseases |
| CN109400618B (zh) * | 2018-11-09 | 2021-08-10 | 中国药科大学 | 一种色满衍生物及其制备方法和应用 |
| WO2020102575A1 (fr) | 2018-11-16 | 2020-05-22 | Inception Ibd, Inc. | Aminothiazoles hétérocycliques et leurs utilisations |
| CN109809992A (zh) * | 2019-02-16 | 2019-05-28 | 安徽华胜医药科技有限公司 | 一种2-（2-氟-3-甲氧基苯基）-2-羟基乙酸乙酯的合成方法 |
| EP4578460A3 (fr) | 2019-05-20 | 2025-08-27 | Pfizer Inc. | Combinaisons comprenant du benzodioxol en tant qu'agonistes de glp-1r destinées à être utilisées dans le traitement de la nash/nafld et de maladies associées |
| CN110128347A (zh) * | 2019-06-17 | 2019-08-16 | 韶远科技（上海)有限公司 | 一种1-甲基-1h-吲唑-6-甲酸的合成方法 |
| GB201910304D0 (en) | 2019-07-18 | 2019-09-04 | Ctxt Pty Ltd | Compounds |
| FI4097099T3 (fi) | 2020-02-07 | 2024-07-30 | Gasherbrum Bio Inc | Heterosyklisiä glp-1-agonisteja |
| PL4143183T3 (pl) | 2020-04-29 | 2026-03-02 | Gasherbrum Bio, Inc. | Heterocykliczni agoniści glp-1 |
| WO2022095971A1 (fr) * | 2020-11-06 | 2022-05-12 | 上海医药集团股份有限公司 | Composé spiro hétérocyclique, son procédé de préparation et son utilisation |
| WO2023169456A1 (fr) | 2022-03-09 | 2023-09-14 | Gasherbrum Bio , Inc. | Agonistes hétérocycliques de glp-1 |
| US20250250269A1 (en) | 2022-04-14 | 2025-08-07 | Gasherbrum Bio, Inc. | Heterocyclic glp-1 agonists |
| WO2024118524A1 (fr) | 2022-11-28 | 2024-06-06 | Cerevel Therapeutics, Llc | Composés d'azaindole et leur utilisation en tant qu'inhibiteurs de phosphodiestérase |
| JP2026501171A (ja) | 2022-12-15 | 2026-01-14 | ガシャーブラム・バイオ・インコーポレイテッド | Ｇｌｐ－１アゴニスト活性を有する化合物の塩および固体形態 |
| WO2025036472A1 (fr) * | 2023-08-16 | 2025-02-20 | Pharmaengine, Inc. | Inhibiteur de prmt5 mta-coopératif spirocyclique |
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| BRPI0613427A2 (pt) * | 2005-07-19 | 2012-10-30 | Merck & Co Inc | composto ou seu sal ou éster, composição farmacêutica, agente terapêutico, e , uso do composto ou seu sal ou éster |
-
2007
- 2007-11-16 AU AU2007326950A patent/AU2007326950B2/en not_active Expired - Fee Related
- 2007-11-16 CN CNA2007800442537A patent/CN101541809A/zh active Pending
- 2007-11-16 JP JP2009538803A patent/JP2010511035A/ja active Pending
- 2007-11-16 BR BRPI0721053-1A patent/BRPI0721053A2/pt not_active IP Right Cessation
- 2007-11-16 US US12/514,596 patent/US20090270435A1/en not_active Abandoned
- 2007-11-16 AP AP2009004880A patent/AP2009004880A0/xx unknown
- 2007-11-16 EA EA200900613A patent/EA200900613A1/ru unknown
- 2007-11-16 WO PCT/IB2007/003639 patent/WO2008065508A1/fr not_active Ceased
- 2007-11-16 AT AT07825738T patent/ATE552262T1/de active
- 2007-11-16 RS RSP-2009/0249A patent/RS20090249A/sr unknown
- 2007-11-16 CA CA2670422A patent/CA2670422C/fr not_active Expired - Fee Related
- 2007-11-16 EP EP07825738A patent/EP2097420B1/fr active Active
- 2007-11-16 MX MX2009005604A patent/MX2009005604A/es not_active Application Discontinuation
- 2007-11-16 KR KR1020097013481A patent/KR20090083956A/ko not_active Ceased
-
2009
- 2009-05-12 ZA ZA200903268A patent/ZA200903268B/xx unknown
- 2009-05-14 NO NO20091889A patent/NO20091889L/no not_active Application Discontinuation
- 2009-05-14 IL IL198779A patent/IL198779A0/en unknown
- 2009-05-22 TN TNP2009000204A patent/TN2009000204A1/fr unknown
- 2009-05-28 CR CR10831A patent/CR10831A/es not_active Application Discontinuation
- 2009-05-28 CO CO09054954A patent/CO6180424A2/es not_active Application Discontinuation
- 2009-05-29 SV SV2009003281A patent/SV2009003281A/es not_active Application Discontinuation
- 2009-05-29 EC EC2009009371A patent/ECSP099371A/es unknown
- 2009-05-29 MA MA31936A patent/MA30932B1/fr unknown
Also Published As
| Publication number | Publication date |
|---|---|
| RS20090249A (sr) | 2010-06-30 |
| KR20090083956A (ko) | 2009-08-04 |
| IL198779A0 (en) | 2010-02-17 |
| JP2010511035A (ja) | 2010-04-08 |
| EP2097420A1 (fr) | 2009-09-09 |
| CN101541809A (zh) | 2009-09-23 |
| ATE552262T1 (de) | 2012-04-15 |
| MA30932B1 (fr) | 2009-11-02 |
| CA2670422C (fr) | 2011-09-06 |
| CA2670422A1 (fr) | 2008-06-05 |
| AU2007326950A1 (en) | 2008-06-05 |
| MX2009005604A (es) | 2009-06-08 |
| EP2097420B1 (fr) | 2012-04-04 |
| WO2008065508A1 (fr) | 2008-06-05 |
| SV2009003281A (es) | 2010-08-17 |
| CO6180424A2 (es) | 2010-07-19 |
| CR10831A (es) | 2009-06-18 |
| BRPI0721053A2 (pt) | 2014-07-29 |
| ECSP099371A (es) | 2009-06-30 |
| ZA200903268B (en) | 2010-07-28 |
| NO20091889L (no) | 2009-06-17 |
| EA200900613A1 (ru) | 2009-10-30 |
| US20090270435A1 (en) | 2009-10-29 |
| TN2009000204A1 (fr) | 2010-10-18 |
| AU2007326950B2 (en) | 2010-10-14 |
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