AR003473A1 - Uso de la l-carnitina o una acil l-carnitina en donde el acilo es seleccionado del grupo que comprende acetilo, propionilo, butirilo, valerilo e isovalerilo, o de una sal farmacologicamente aceptable de las mismas para la produccion de un medicamento - Google Patents

Uso de la l-carnitina o una acil l-carnitina en donde el acilo es seleccionado del grupo que comprende acetilo, propionilo, butirilo, valerilo e isovalerilo, o de una sal farmacologicamente aceptable de las mismas para la produccion de un medicamento

Info

Publication number
AR003473A1
AR003473A1 ARP960103845A AR10384596A AR003473A1 AR 003473 A1 AR003473 A1 AR 003473A1 AR P960103845 A ARP960103845 A AR P960103845A AR 10384596 A AR10384596 A AR 10384596A AR 003473 A1 AR003473 A1 AR 003473A1
Authority
AR
Argentina
Prior art keywords
acil
carnitine
pharmacologically acceptable
isovaleril
butyrile
Prior art date
Application number
ARP960103845A
Other languages
English (en)
Original Assignee
Sigma Tau Ind Farmaceuti
Mendes Srl
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sigma Tau Ind Farmaceuti, Mendes Srl filed Critical Sigma Tau Ind Farmaceuti
Publication of AR003473A1 publication Critical patent/AR003473A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/205—Amine addition salts of organic acids; Inner quaternary ammonium salts, e.g. betaine, carnitine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A61K31/221—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin with compounds having an amino group, e.g. acetylcholine, acetylcarnitine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4172—Imidazole-alkanecarboxylic acids, e.g. histidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Emergency Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Se revela el uso terapéutico de aminoácidos básicos, aminoácidos básicos acilados y sus sales farmacológicamente aceptables para la preparación de unmedicamento para la profilaxis de enfermedades o el tratamiento terapéutico de trastornoscelu lares acompanados por altos niveles de ceramida, tales comolas inflamaciones intestinales, la coagulación intravascular difusa, fiebre, catabolismo de proteínas, endomiocarditis, trombosis capilar, etc.
ARP960103845A 1995-08-03 1996-08-02 Uso de la l-carnitina o una acil l-carnitina en donde el acilo es seleccionado del grupo que comprende acetilo, propionilo, butirilo, valerilo e isovalerilo, o de una sal farmacologicamente aceptable de las mismas para la produccion de un medicamento AR003473A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT95RM000545A IT1277898B1 (it) 1995-08-03 1995-08-03 Uso di amminoacidi basici, di acil derivati di amminoacidi basici e di loro sali farmaceuticamente accettabili per la profilassi di malattie

Publications (1)

Publication Number Publication Date
AR003473A1 true AR003473A1 (es) 1998-08-05

Family

ID=11403513

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP960103845A AR003473A1 (es) 1995-08-03 1996-08-02 Uso de la l-carnitina o una acil l-carnitina en donde el acilo es seleccionado del grupo que comprende acetilo, propionilo, butirilo, valerilo e isovalerilo, o de una sal farmacologicamente aceptable de las mismas para la produccion de un medicamento

Country Status (18)

Country Link
US (2) US6114385A (es)
EP (1) EP0844875B1 (es)
JP (1) JPH11510182A (es)
KR (1) KR100423760B1 (es)
CN (1) CN1138539C (es)
AR (1) AR003473A1 (es)
AT (1) ATE349206T1 (es)
AU (1) AU713207B2 (es)
BR (1) BR9610106A (es)
CA (1) CA2228281C (es)
DE (1) DE69636792T2 (es)
DK (1) DK0844875T3 (es)
ES (1) ES2279523T3 (es)
IT (1) IT1277898B1 (es)
PT (1) PT844875E (es)
RU (1) RU2179850C2 (es)
TW (1) TW434011B (es)
WO (1) WO1997005862A2 (es)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1277898B1 (it) 1995-08-03 1997-11-12 Mendes Srl Uso di amminoacidi basici, di acil derivati di amminoacidi basici e di loro sali farmaceuticamente accettabili per la profilassi di malattie
IT1277897B1 (it) * 1995-08-03 1997-11-12 Mendes Srl Uso della l-carnitina,di suoi derivati e di loro sali farmaceuticamen- te accettabili in combinazione con farmaci antiretrovirali per ridurre
IT1284661B1 (it) * 1996-06-06 1998-05-21 Sigma Tau Ind Farmaceuti Uso di alcanoil l-carnitine nel trattamento terapeutico di malattie infiammatorie croniche intestinali.
FR2778562B1 (fr) * 1998-05-14 2000-08-04 Sephra Composition pharmaceutique, hygienique et/ou cosmetique contenant de l'eau de mer et de l'arginine
ES2235499T3 (es) * 1998-07-30 2005-07-01 Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. Uso de derivados de propionil l-carnitina y de acetil l-carnitina en la preparacion de medicamentos con actividad anticancerigena.
IT1302289B1 (it) 1998-09-30 2000-09-05 Univ Catania Composizioni farmaceutiche ad attivita' antineoplastica
CA2367002A1 (en) * 1999-03-19 2000-09-28 Michael A. Moskowitz Increasing cerebral bioavailability of drugs
US20010025027A1 (en) * 2000-03-07 2001-09-27 Sonis Stephen T. Inhibition of ceramide for the prevention and treatment of oral mucositis induced by antineoplastic drugs or radiation
WO2002060431A1 (en) * 2001-01-30 2002-08-08 Ajinomoto Co., Inc. Remedies/preventives for inflammatory diseases
US20080145424A1 (en) * 2002-10-24 2008-06-19 Enos Phramaceuticals, Inc. Sustained release L-arginine formulations and methods of manufacture and use
EP1562555A2 (en) * 2002-10-24 2005-08-17 Enos Pharmaceuticals, Inc. Sustained release l-arginine formulations and methods of manufacture and use
IL156670A0 (en) * 2003-06-26 2004-01-04 Zvi Zolotariov Aloe suppositories
JP2007521324A (ja) * 2003-09-29 2007-08-02 エノス ファーマシューティカルズ， インク． 徐放性ｌ−アルギニン調合物並びにその製造法及び使用法
JP2007055900A (ja) * 2003-12-15 2007-03-08 Ajinomoto Co Inc 炎症性疾患の治療及び予防用医薬組成物
US20050232911A1 (en) * 2004-04-19 2005-10-20 Schreiber Brian D Prevention and treatment of metabolic abnormalities associated with excess intramyocellular lipid
RU2268718C1 (ru) * 2004-11-09 2006-01-27 Казанский государственный медицинский университет Способ предотвращения развития осложнений экспериментального инфаркта миокарда у крыс
EA019268B1 (ru) * 2010-12-01 2014-02-28 Общество С Ограниченной Ответственностью "Анвилаб" Комбинированное средство, обладающее гепатопротекторным действием
CN103142735B (zh) * 2013-03-09 2014-07-23 河北工程大学 一种治疗鸭病毒性肝炎的中药口服液
EP3764103A1 (en) * 2019-07-12 2021-01-13 Urgo Recherche Innovation Et Developpement Method of diagnosis or prognosis of a non-healing or chronic wound
US20230346735A1 (en) * 2020-04-28 2023-11-02 Lonza Greenwood Llc Nutritional Composition Comprising Carnitine and Method for Treating or Preventing an Infection in a Mammal
US20250360158A1 (en) * 2022-06-13 2025-11-27 Neubase Therapeutics, Inc. Oligonucleotide analogue formulations

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU518617B2 (en) * 1977-04-29 1981-10-08 Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. Therapeutic application of acetyl-d, 1-carnitine
DE2946563C2 (de) * 1979-11-17 1987-04-30 B. Braun Melsungen Ag, 3508 Melsungen Aminosäurelösung zur parenteralen Infusion
JPH0247447B2 (ja) * 1982-05-27 1990-10-19 Teijin Ltd Kohotaikanohikuiigmsoseibutsu
JPS6130567A (ja) * 1984-07-23 1986-02-12 Shiseido Co Ltd 尿素の安定化法
JPH02124822A (ja) * 1988-11-02 1990-05-14 Eisai Co Ltd セファロスポリン含有注射用組成物
IT1224842B (it) * 1988-12-27 1990-10-24 Sigma Tau Ind Farmaceuti Uso di derivati della l-carnitina nel trattamento terapeutico delle alterazioni degenerative del sistema nervoso
US6294520B1 (en) * 1989-03-27 2001-09-25 Albert T. Naito Material for passage through the blood-brain barrier
EP0400547A1 (en) * 1989-06-02 1990-12-05 Abbott Laboratories Parenteral nutrition product
IT1244636B (it) * 1991-01-04 1994-08-08 Sigma Tau Ind Farmaceuti Uso dell'acetil l-carnitina nel trattamento terapeutico del coma e composizioni farmaceutiche utili in tale trattamento.
IT1248321B (it) * 1991-05-15 1995-01-05 Sigma Tau Ind Farmaceuti Uso di esteri di acil l-carnitine con l'acido gamma-idrossibutirrico per produrre composizioni farmaceutiche per il trattamento di epatopatie
IT1245869B (it) * 1991-06-05 1994-10-25 Sigma Tau Ind Farmaceuti Impiego di propionil l-carnitina per il recupero del tono muscolare in soggetti immobilizzati
IT1254136B (it) * 1992-01-16 1995-09-08 Sigma Tau Ind Farmaceuti Esteri di acil carnitine con alcooli alifatici a lunga catena e composizioni farmaceutiche che li contengono, ad attivita' antimicotica.
AU6922994A (en) * 1993-06-21 1995-01-17 Bernardini, Attilio Use of acylcarnitin to treat illnesses caused by aids
IT1277898B1 (it) 1995-08-03 1997-11-12 Mendes Srl Uso di amminoacidi basici, di acil derivati di amminoacidi basici e di loro sali farmaceuticamente accettabili per la profilassi di malattie
IT1277897B1 (it) 1995-08-03 1997-11-12 Mendes Srl Uso della l-carnitina,di suoi derivati e di loro sali farmaceuticamen- te accettabili in combinazione con farmaci antiretrovirali per ridurre
IT1283951B1 (it) 1996-03-15 1998-05-07 Mendes Srl Uso della acetil l-carnitina o dei suoi sali farmacologicamente accettabili per il trattamento terapeutico o la profilassi di

Also Published As

Publication number Publication date
CN1138539C (zh) 2004-02-18
US6114385A (en) 2000-09-05
WO1997005862A2 (en) 1997-02-20
JPH11510182A (ja) 1999-09-07
EP0844875A2 (en) 1998-06-03
BR9610106A (pt) 1999-02-23
DK0844875T3 (da) 2007-04-10
IT1277898B1 (it) 1997-11-12
CA2228281A1 (en) 1997-02-20
CN1193911A (zh) 1998-09-23
WO1997005862A3 (en) 1997-04-17
US6350782B1 (en) 2002-02-26
EP0844875B1 (en) 2006-12-27
ITRM950545A1 (it) 1997-02-03
DE69636792D1 (de) 2007-02-08
MX9800916A (es) 1998-10-31
KR100423760B1 (ko) 2004-08-25
DE69636792T2 (de) 2007-10-04
ES2279523T3 (es) 2007-08-16
ATE349206T1 (de) 2007-01-15
HK1015274A1 (en) 1999-10-15
TW434011B (en) 2001-05-16
RU2179850C2 (ru) 2002-02-27
AU6469196A (en) 1997-03-05
KR19990036148A (ko) 1999-05-25
CA2228281C (en) 2008-03-25
AU713207B2 (en) 1999-11-25
ITRM950545A0 (it) 1995-08-03
PT844875E (pt) 2007-02-28

Similar Documents

Publication Publication Date Title
AR003473A1 (es) Uso de la l-carnitina o una acil l-carnitina en donde el acilo es seleccionado del grupo que comprende acetilo, propionilo, butirilo, valerilo e isovalerilo, o de una sal farmacologicamente aceptable de las mismas para la produccion de un medicamento
BR9611015A (pt) Composto, composição farmacêutica e processo para o tratamento de uma doença inflamatória suscetìvel ao tratamento com um agente não-tóxico anti-inflamatório não-esteróide, sal farmaceuticamente aceitável, utilização de um composto
FI20105844L (fi) Farmaseuttisia koostumuksia IL-6:n tuoton aiheuttamien sairauksien hoitoon
BR0009042A (pt) Composto, uso do mesmo, processo para prepararum composto, composição farmacêutica, e, métodospara tratar uma doença em um animal em que aatividade de cisteìna protease contribui para apatologia e/ou sintomatologia da doença, e paratratar uma doença em um animal em que a atividadede catepsina s contribui para a patologia e/ousintomatologia da doença
EA200100524A1 (ru) Амиды антраниловой кислоты и их применение в качестве лекарственных средств
ES2128846T3 (es) Utilizacion del fumagilol y sus derivados para preparar los medicamentos destinados a combatir las infecciones intestinales.
DE69629273D1 (de) Zusammensetzungen enthaltend Propionyl-L-Carnitine und Hydroxyzitronensäure oder Pantothensäure
MA26901A1 (fr) Nouvelle composition pharmaceutique
ES467828A1 (es) Un procedimiento para preparar nuevos compuestos de cefem y cefam
ES2178291T3 (es) Uso de acidos 3-benzoil-aceticos, esteres, o amidas para el tratamiento del glaucoma glc1a.
BR0114344A (pt) Retinóides para o tratamento de enfisema
EA199800721A1 (ru) Ингибитор реваскуляризации
ES2142030T3 (es) Nuevos compuestos espiro-heterociclicos, su procedimiento de preparacion y las composiciones farmaceuticas que los contienen.
DK0451654T3 (da) Anvendelse af N-alkylerede 1,4-dihydropyridin-dicarboxylsyreestere som lægemidler, nye forbindelser og fremgangsmåder til deres fremstilling
ITRM930356A0 (it) Uso di esteri sull'ossidrile della l-carnitina per produrre composizioni farmaceutiche per il trattamento di affezioni cutanee.
ES2193722T3 (es) Desformoterol y procedimiento para su preparacion.
BR9807936A (pt) Preparação farmacêutica imuno-tolerante de complexo de pró-trombina, processo para a produção de uma preparação, e, utilização de uma preparação
AR012723A1 (es) Derivados triptolidos utiles en el tratamiento de enfermedades autoinmunes y usos en la fabricacion de medicamentos
PA8429701A1 (es) Inhibicion de las metaloproteasas de matriz por acidos biariloxobutiricos sustituidos
AR016382A1 (es) Uso de un derivado del acido bencil-indazol metoxialcanoico.
ITRM930365A0 (it) Uso di esteri sull'ossidrile della l-carnitina con acidi aromatici perprodurre composizioni farmaceutiche per il trattamento di affezioni cutanee.
CO4480025A1 (es) Nuevos usos de ciertos derivados del indol en el tratamiento o profilaxis de trastornos medicos
ES2187030T3 (es) Una nueva sal.
NO844889L (no) Oksicam-derivater og fremgangsmaate til deres fremstilling
IT8920358A0 (it) Impiego di derivati della fosfatidil carnitina per la preparazione di composizioni farmaceutiche aventi attivita' nella terapia delle patologie dell'uomo associate con un danno neuronale.

Legal Events

Date Code Title Description
FC Refusal