AT409863B - Hoch effiziente expression eines polypeptids, das eine modifizierte pres1-region des grossen hepatitis b-virus-antigens enthält - Google Patents

Hoch effiziente expression eines polypeptids, das eine modifizierte pres1-region des grossen hepatitis b-virus-antigens enthält Download PDF

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Publication number
AT409863B
AT409863B AT0150494A AT150494A AT409863B AT 409863 B AT409863 B AT 409863B AT 0150494 A AT0150494 A AT 0150494A AT 150494 A AT150494 A AT 150494A AT 409863 B AT409863 B AT 409863B
Authority
AT
Austria
Prior art keywords
antigen
pres1
virus
promoter
cell
Prior art date
Application number
AT0150494A
Other languages
German (de)
English (en)
Other versions
ATA150494A (de
Inventor
Friedrich Dorner
Michael Dr Pfleiderer
Falko-Guenter Dr Falkner
Original Assignee
Immuno Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Immuno Ag filed Critical Immuno Ag
Publication of ATA150494A publication Critical patent/ATA150494A/de
Application granted granted Critical
Publication of AT409863B publication Critical patent/AT409863B/de

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/576Immunoassay; Biospecific binding assay; Materials therefor for hepatitis
    • G01N33/5761Hepatitis B
    • G01N33/5764Hepatitis B surface antigen
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525Virus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2730/00Reverse transcribing DNA viruses
    • C12N2730/00011Details
    • C12N2730/10011Hepadnaviridae
    • C12N2730/10111Orthohepadnavirus, e.g. hepatitis B virus
    • C12N2730/10122New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/975Kit
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00Chemistry: analytical and immunological testing
    • Y10S436/82Hepatitis associated antigens and antibodies

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Organic Chemistry (AREA)
  • Virology (AREA)
  • Physics & Mathematics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Communicable Diseases (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Food Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
AT0150494A 1993-07-30 1994-07-29 Hoch effiziente expression eines polypeptids, das eine modifizierte pres1-region des grossen hepatitis b-virus-antigens enthält AT409863B (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US9935193A 1993-07-30 1993-07-30

Publications (2)

Publication Number Publication Date
ATA150494A ATA150494A (de) 2002-04-15
AT409863B true AT409863B (de) 2002-12-27

Family

ID=22274582

Family Applications (1)

Application Number Title Priority Date Filing Date
AT0150494A AT409863B (de) 1993-07-30 1994-07-29 Hoch effiziente expression eines polypeptids, das eine modifizierte pres1-region des grossen hepatitis b-virus-antigens enthält

Country Status (4)

Country Link
US (2) US6077691A (fr)
EP (1) EP0637631A3 (fr)
AT (1) AT409863B (fr)
CA (1) CA2129156A1 (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0753581A1 (fr) 1995-07-10 1997-01-15 Immuno Ag Virus recombinantes eucaryotes cytoplasmiques améliorés, un procédé pour leur préparation et leur utilisation comme vaccins
TWI691598B (zh) * 2015-10-08 2020-04-21 台灣生物製劑股份有限公司 以整體表現細胞作為抗原載體及其於製備疫苗或診斷試劑及篩選單株抗體之應用
JP2020108355A (ja) * 2019-01-07 2020-07-16 公益財団法人ヒューマンサイエンス振興財団 B型肝炎ウイルス株

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0414374A2 (fr) * 1989-07-25 1991-02-27 Smithkline Biologicals S.A. Antigènes ainsi que les méthodes pour leur préparation
US5077213A (en) * 1988-11-10 1991-12-31 Shanghai Institute Of Biochemistry, Chinese Academy Of Sciences Recombinant vaccinia virus

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4847080A (en) * 1984-03-07 1989-07-11 New York Blood Center, Inc. Pre-S gene coded peptide hepatitis B immunogens, vaccines, diagnostics, and synthetic lipide vesicle carriers
EP1088830A3 (fr) * 1987-06-22 2004-04-07 Medeva Holdings B.V. Particules de l'antigène de surface de l'hépatitie B

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5077213A (en) * 1988-11-10 1991-12-31 Shanghai Institute Of Biochemistry, Chinese Academy Of Sciences Recombinant vaccinia virus
EP0414374A2 (fr) * 1989-07-25 1991-02-27 Smithkline Biologicals S.A. Antigènes ainsi que les méthodes pour leur préparation

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
CHENG ET AL., JOURNAL OF VIROLOGY (1986), V. 60, NO. 2, S. 337-344 *
ELROY-STEIN ET AL., PROC. NATL. ACAD. SCI. (1989), V. 86, S. 6126-6130 *
FÜRST ET AL., MOL. AND CELL. BIOLOGY (1987), V. 7, NO. 7, S. 2538-2544 *
NEMECKOVA ET AL., ARCH. VIROL. (1991), V. 121, S. 29-41 *

Also Published As

Publication number Publication date
US6077691A (en) 2000-06-20
EP0637631A3 (fr) 1996-08-21
ATA150494A (de) 2002-04-15
EP0637631A2 (fr) 1995-02-08
CA2129156A1 (fr) 1995-01-31
US6004561A (en) 1999-12-21

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AT409863B (de) Hoch effiziente expression eines polypeptids, das eine modifizierte pres1-region des grossen hepatitis b-virus-antigens enthält

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UEP Publication of translation of european patent specification
ELJ Ceased due to non-payment of the annual fee