ATA57598A - Neues salz von 7-(2-(aminothiazol-4yl)-2- - Google Patents

Neues salz von 7-(2-(aminothiazol-4yl)-2-

Info

Publication number
ATA57598A
ATA57598A AT0057598A AT57598A ATA57598A AT A57598 A ATA57598 A AT A57598A AT 0057598 A AT0057598 A AT 0057598A AT 57598 A AT57598 A AT 57598A AT A57598 A ATA57598 A AT A57598A
Authority
AT
Austria
Prior art keywords
aminothiazol
new salt
cefixime
salt
ceph
Prior art date
Application number
AT0057598A
Other languages
English (en)
Other versions
AT406773B (de
Inventor
Martin Dr Decristoforo
Johannes Dr Ludescher
Hubert Dr Sturm
Werner Dr Veit
Original Assignee
Biochemie Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to AT0057598A priority Critical patent/AT406773B/de
Application filed by Biochemie Gmbh filed Critical Biochemie Gmbh
Priority to JP2000542328A priority patent/JP2002510694A/ja
Priority to DE69937143T priority patent/DE69937143T2/de
Priority to HK01104565.6A priority patent/HK1034078B/en
Priority to BR9909898-9A priority patent/BR9909898A/pt
Priority to IDW20001932A priority patent/ID26210A/id
Priority to CNB998046205A priority patent/CN1134447C/zh
Priority to ES99917938T priority patent/ES2293720T3/es
Priority to EP99917938A priority patent/EP1068211B1/de
Priority to CA002326441A priority patent/CA2326441C/en
Priority to AU36035/99A priority patent/AU3603599A/en
Priority to AT99917938T priority patent/ATE373666T1/de
Priority to PCT/EP1999/002222 priority patent/WO1999051607A2/en
Priority to TR2000/02838T priority patent/TR200002838T2/xx
Priority to KR1020007010634A priority patent/KR20010034671A/ko
Publication of ATA57598A publication Critical patent/ATA57598A/de
Application granted granted Critical
Publication of AT406773B publication Critical patent/AT406773B/de
Priority to ZA200004899A priority patent/ZA200004899B/xx
Priority to US10/261,748 priority patent/US6825345B2/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/22—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with radicals containing only hydrogen and carbon atoms, attached in position 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
    • C07D277/62—Benzothiazoles
    • C07D277/68—Benzothiazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D277/70—Sulfur atoms
    • C07D277/74—Sulfur atoms substituted by carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Peptides Or Proteins (AREA)
AT0057598A 1998-04-02 1998-04-02 Neues salz von 7-(2-(aminothiazol-4yl)-2- AT406773B (de)

Priority Applications (17)

Application Number Priority Date Filing Date Title
AT0057598A AT406773B (de) 1998-04-02 1998-04-02 Neues salz von 7-(2-(aminothiazol-4yl)-2-
AU36035/99A AU3603599A (en) 1998-04-02 1999-03-31 Process for purification of a cephalosporin derivative
HK01104565.6A HK1034078B (en) 1998-04-02 1999-03-31 Process for purification of a cephalosporin derivative
BR9909898-9A BR9909898A (pt) 1998-04-02 1999-03-31 Processo para purificação de um derivado de cefalosporina
IDW20001932A ID26210A (id) 1998-04-02 1999-03-31 Proses pemurnian turunan sefalosporin
CNB998046205A CN1134447C (zh) 1998-04-02 1999-03-31 头孢克肟叔辛基铵盐、其制备方法和用于提纯头孢克肟的方法
ES99917938T ES2293720T3 (es) 1998-04-02 1999-03-31 Procedimiento para la purificacion de un derivado de cefalosporina.
EP99917938A EP1068211B1 (de) 1998-04-02 1999-03-31 Verfahren zur reinigung eines cephalosporin-derivats
JP2000542328A JP2002510694A (ja) 1998-04-02 1999-03-31 セファロスポリン誘導体の精製方法
DE69937143T DE69937143T2 (de) 1998-04-02 1999-03-31 Verfahren zur reinigung eines cephalosporin-derivats
AT99917938T ATE373666T1 (de) 1998-04-02 1999-03-31 Verfahren zur reinigung eines cephalosporin- derivats
PCT/EP1999/002222 WO1999051607A2 (en) 1998-04-02 1999-03-31 Process for purification of a cephalosporin derivative
TR2000/02838T TR200002838T2 (tr) 1998-04-02 1999-03-31 Bir sefalosporin türevinin arıtımı için proses
KR1020007010634A KR20010034671A (ko) 1998-04-02 1999-03-31 세팔로스포린 유도체의 정제방법
CA002326441A CA2326441C (en) 1998-04-02 1999-03-31 Process for purification of a cephalosporin derivative
ZA200004899A ZA200004899B (en) 1998-04-02 2000-09-14 Process for purification of a cephalosporin derivative.
US10/261,748 US6825345B2 (en) 1998-04-02 2002-09-30 Process for purification of a cephalosporin derivative

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
AT0057598A AT406773B (de) 1998-04-02 1998-04-02 Neues salz von 7-(2-(aminothiazol-4yl)-2-

Publications (2)

Publication Number Publication Date
ATA57598A true ATA57598A (de) 2000-01-15
AT406773B AT406773B (de) 2000-08-25

Family

ID=3494225

Family Applications (2)

Application Number Title Priority Date Filing Date
AT0057598A AT406773B (de) 1998-04-02 1998-04-02 Neues salz von 7-(2-(aminothiazol-4yl)-2-
AT99917938T ATE373666T1 (de) 1998-04-02 1999-03-31 Verfahren zur reinigung eines cephalosporin- derivats

Family Applications After (1)

Application Number Title Priority Date Filing Date
AT99917938T ATE373666T1 (de) 1998-04-02 1999-03-31 Verfahren zur reinigung eines cephalosporin- derivats

Country Status (15)

Country Link
US (1) US6825345B2 (de)
EP (1) EP1068211B1 (de)
JP (1) JP2002510694A (de)
KR (1) KR20010034671A (de)
CN (1) CN1134447C (de)
AT (2) AT406773B (de)
AU (1) AU3603599A (de)
BR (1) BR9909898A (de)
CA (1) CA2326441C (de)
DE (1) DE69937143T2 (de)
ES (1) ES2293720T3 (de)
ID (1) ID26210A (de)
TR (1) TR200002838T2 (de)
WO (1) WO1999051607A2 (de)
ZA (1) ZA200004899B (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT404727B (de) * 1997-01-16 1999-02-25 Biochemie Gmbh Kristallines salz von cefixim und verfahren zu dessen herstellung
ITMI20012364A1 (it) * 2001-11-09 2003-05-09 Antibioticos Spa Processo di sintesi della cefixima via alchil-o arilsolfonati
WO2004046154A1 (en) * 2002-11-15 2004-06-03 Orchid Chemicals & Pharmaceuticals Ltd Novel amorphous hydrate of a cephalosporin antibiotic
US7662955B2 (en) * 2003-03-20 2010-02-16 Orchid Chemicals And Pharmaceuticals Ltd. Process for the preparation of cefoxitin
US8008478B2 (en) 2004-12-21 2011-08-30 Lupin Limited Process for the preparation of cefixime
PL1863822T3 (pl) * 2005-03-29 2010-03-31 Hetero Drugs Ltd Ulepszony sposób wytwarzania cefiksymu
CN1312158C (zh) * 2005-05-20 2007-04-25 天津市医药集团技术发展有限公司 一种头孢克肟的制备方法
CN101812075B (zh) * 2010-05-07 2012-06-13 郝志艳 一种头孢克肟化合物及其新制法
CN103265562A (zh) * 2013-05-29 2013-08-28 四川方向药业有限责任公司 头孢克肟的制备方法
CN103965217A (zh) * 2014-05-21 2014-08-06 广州白云山制药股份有限公司广州白云山化学制药厂 3-三嗪环-7-（噻唑羧甲氧亚氨基）头孢烷酸的制备方法
CN103965216A (zh) * 2014-05-21 2014-08-06 广州白云山制药股份有限公司广州白云山化学制药厂 7-（噻唑羧甲氧亚氨基)- 3-三嗪环头孢化合物的制造方法
WO2016142902A1 (en) * 2015-03-11 2016-09-15 Lupin Limited Cefixime with reduced surface area and high stability

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA806977B (en) * 1979-11-19 1981-10-28 Fujisawa Pharmaceutical Co 7-acylamino-3-vinylcephalosporanic acid derivatives and processes for the preparation thereof
JPS58986A (ja) * 1981-05-07 1983-01-06 Fujisawa Pharmaceut Co Ltd セフェム化合物
JPS57192392A (en) * 1981-05-19 1982-11-26 Sankyo Co Ltd Production of 3-alkoxymethylcephalosporin
AU564150B2 (en) * 1982-04-30 1987-08-06 Takeda Chemical Industries Ltd. 1-sulfo-2-azetidinone derivatives
EP0096297B1 (de) * 1982-06-03 1988-06-15 F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft Verfahren zur Herstellung von 1-Sulfo-2-oxoazetidinderivaten
DE3372768D1 (de) 1982-06-03 1987-09-03 Hoffmann La Roche 1-sulfo-2-oxoazetidine derivatives
JPS59163387A (ja) * 1983-03-07 1984-09-14 Sankyo Co Ltd ３−アルコキシメチルセフアロスポリンの製造方法
JPH0692416B2 (ja) * 1985-03-13 1994-11-16 三共株式会社 セフアロスポラン酸誘導体
US5359057A (en) 1986-02-07 1994-10-25 Hoffmann-La Roche Inc. Acylation of amines
ES2042507T3 (es) * 1986-02-07 1993-12-16 Hoffmann La Roche Procedimiento para la obtencion de carboxiamidas.
JPH01242589A (ja) * 1988-03-22 1989-09-27 Fujisawa Pharmaceut Co Ltd セフエム化合物
EP0630380B1 (de) * 1992-02-05 2001-09-05 Biochemie Gesellschaft M.B.H. Verfahren zur reinigung eines 3-cephem-4-carboxyl säure derivates
DE69427312T2 (de) * 1993-11-17 2001-08-23 Biochemie Ges.M.B.H., Kundl Trennung von Cephalosporinisomeren
AT403049B (de) * 1995-08-14 1997-10-27 Biochemie Gmbh Abreicherung von 7-adca in 3-vinyl-aca
AT404251B (de) * 1996-08-14 1998-10-27 Biochemie Gmbh Neues kristallines salz von cefixim
EP0831093A1 (de) * 1996-09-23 1998-03-25 F. Hoffmann-La Roche Ag 1-Carba-(desthia)-cephalosporinderivate
TW538045B (en) * 1997-01-16 2003-06-21 Biochemie Gmbh Process for purifying cefixime

Also Published As

Publication number Publication date
BR9909898A (pt) 2000-12-26
AT406773B (de) 2000-08-25
US6825345B2 (en) 2004-11-30
WO1999051607A3 (en) 2000-01-27
ES2293720T3 (es) 2008-03-16
AU3603599A (en) 1999-10-25
CA2326441A1 (en) 1999-10-14
CA2326441C (en) 2008-03-18
JP2002510694A (ja) 2002-04-09
ZA200004899B (en) 2001-12-24
DE69937143T2 (de) 2008-06-12
ID26210A (id) 2000-12-07
CN1134447C (zh) 2004-01-14
CN1295576A (zh) 2001-05-16
ATE373666T1 (de) 2007-10-15
HK1034078A1 (en) 2001-10-12
TR200002838T2 (tr) 2001-02-21
EP1068211A2 (de) 2001-01-17
WO1999051607A2 (en) 1999-10-14
DE69937143D1 (de) 2007-10-31
EP1068211B1 (de) 2007-09-19
KR20010034671A (ko) 2001-04-25
US20030208065A1 (en) 2003-11-06

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