ATE235478T1 - Verfahren zur herstellung von citalopram - Google Patents

Verfahren zur herstellung von citalopram

Info

Publication number: ATE235478T1
Authority: AT; Austria
Prior art keywords: producing citalopram; citalopram; producing
Prior art date: 1999-06-25

Application number

AT99968622T

Other languages

English (en)

Inventor

Hans Petersen

Michael Harold Rock

Henrik Svane

Original Assignee

Lundbeck & Co As H

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1999-06-25

Filing date

1999-11-22

Publication date

2003-04-15

1999-11-22 Application filed by Lundbeck & Co As H filed Critical Lundbeck & Co As H

2003-04-15 Application granted granted Critical

2003-04-15 Publication of ATE235478T1 publication Critical patent/ATE235478T1/de

Links

WSEQXVZVJXJVFP-UHFFFAOYSA-N 1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile Chemical compound O1CC2=CC(C#N)=CC=C2C1(CCCN(C)C)C1=CC=C(F)C=C1 WSEQXVZVJXJVFP-UHFFFAOYSA-N 0.000 title 1
229960001653 citalopram Drugs 0.000 title 1
238000004519 manufacturing process Methods 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/87—Benzo [c] furans; Hydrogenated benzo [c] furans
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
- A61K31/343—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J23/00—Catalysts comprising metals or metal oxides or hydroxides, not provided for in group B01J21/00
- B01J23/38—Catalysts comprising metals or metal oxides or hydroxides, not provided for in group B01J21/00 of noble metals
- B01J23/40—Catalysts comprising metals or metal oxides or hydroxides, not provided for in group B01J21/00 of noble metals of the platinum group metals
- B01J23/44—Palladium
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
- C07D307/81—Radicals substituted by nitrogen atoms not forming part of a nitro radical

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Chemical Kinetics & Catalysis (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Engineering & Computer Science (AREA)
General Chemical & Material Sciences (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Pain & Pain Management (AREA)
Bioinformatics & Cheminformatics (AREA)
Biomedical Technology (AREA)
Epidemiology (AREA)
Rheumatology (AREA)
Psychiatry (AREA)
Materials Engineering (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Catalysts (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Steroid Compounds (AREA)

AT99968622T 1999-06-25 1999-11-22 Verfahren zur herstellung von citalopram ATE235478T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
DKPA199900920		1999-06-25
PCT/DK1999/000640 WO2000013648A2 (en)	1999-06-25	1999-11-22	Method for the preparation of citalopram

Publications (1)

Publication Number	Publication Date
ATE235478T1 true ATE235478T1 (de)	2003-04-15

Family

ID=8099035

Family Applications (3)

Application Number	Title	Priority Date	Filing Date
AT99968622T ATE235478T1 (de)	1999-06-25	1999-11-22	Verfahren zur herstellung von citalopram
AT0904199A AT409961B (de)	1999-06-25	1999-11-22	Verfahren zur herstellung von citalopram
AT0018401U AT4365U1 (de)	1999-06-25	2001-03-13	Verfahren zur herstellung von citalopram

Family Applications After (2)

Application Number	Title	Priority Date	Filing Date
AT0904199A AT409961B (de)	1999-06-25	1999-11-22	Verfahren zur herstellung von citalopram
AT0018401U AT4365U1 (de)	1999-06-25	2001-03-13	Verfahren zur herstellung von citalopram

Country Status (36)

Country	Link
US (2)	US20020077353A1 (de)
EP (1)	EP1159274B1 (de)
JP (1)	JP3447267B2 (de)
KR (1)	KR100491368B1 (de)
CN (2)	CN1140521C (de)
AR (1)	AR020863A1 (de)
AT (3)	ATE235478T1 (de)
AU (2)	AU1374500A (de)
BG (1)	BG65574B1 (de)
BR (1)	BR9917368B1 (de)
CA (2)	CA2475401A1 (de)
CH (1)	CH691305A5 (de)
CZ (1)	CZ292198B6 (de)
DE (2)	DE19983487C1 (de)
DK (2)	DK1159274T3 (de)
EA (1)	EA002560B1 (de)
ES (2)	ES2189699A1 (de)
FI (1)	FI108641B (de)
GB (2)	GB2357761B (de)
HK (1)	HK1049002B (de)
HU (1)	HUP0103235A3 (de)
IL (2)	IL145959A0 (de)
IS (1)	IS2343B (de)
IT (1)	ITMI991581A1 (de)
MX (1)	MXPA01010989A (de)
NO (1)	NO328542B1 (de)
NZ (1)	NZ514979A (de)
PL (1)	PL205579B1 (de)
PT (1)	PT1159274E (de)
SE (1)	SE516690C2 (de)
SI (1)	SI1159274T1 (de)
SK (1)	SK285813B6 (de)
TR (1)	TR200103702T2 (de)
UA (1)	UA63034C2 (de)
WO (1)	WO2000013648A2 (de)
ZA (1)	ZA200108854B (de)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IL143422A0 (en)	1998-12-23	2002-04-21	Lundbeck & Co As H	Method for the preparation of 5-cyanophthalide
AR022329A1 (es)	1999-01-29	2002-09-04	Lundbeck & Co As H	Metodo para la preparacion de 5-cianoftalida
DK1173431T4 (da)	1999-04-14	2010-01-04	Lundbeck & Co As H	Fremgangsmåde til fremstilling af citalopram
ITMI991579A1 (it)	1999-06-25	2001-01-15	Lundbeck & Co As H	Metodo per la preparazione di citalopram
HRP20020344B1 (hr)	1999-10-25	2010-10-31	H. Lundbeck A/S	Način priprave citaloprama
GB2360281B (en)	1999-10-25	2002-01-16	Lundbeck & Co As H	Method for the preparation of citalopram
AR026063A1 (es)	1999-11-01	2002-12-26	Lundbeck & Co As H	Metodo para la preparacion de 5-carboxiftalida.
HUP0203635A3 (en)	1999-12-28	2005-02-28	Lundbeck & Co As H	Method for the preparation of citalopram
PT1246813E (pt)	1999-12-30	2004-02-27	Lundbeck & Co As H	Metodo para a preparacao de citalopram
CN1195749C (zh)	2000-01-14	2005-04-06	H.隆德贝克有限公司	制备5－氰基2－苯并[c]呋喃酮的方法
NL1017415C1 (nl)	2000-02-24	2001-05-18	Lundbeck & Co As H	Werkwijze voor de bereiding van Citalopram.
NL1017417C1 (nl)	2000-03-03	2001-03-16	Lundbeck & Co As H	Werkwijze voor de bereiding van Citalopram.
IES20010206A2 (en)	2000-03-13	2002-03-06	Lundbeck & Co As H	Method for the preparation of citalopram
GB2357762B (en) *	2000-03-13	2002-01-30	Lundbeck & Co As H	Crystalline base of citalopram
CN1427835A (zh)	2000-03-13	2003-07-02	H·隆德贝克有限公司	5－取代的1－(4－氟苯基)－1,3－二氢异苯并呋喃的分步烷基化
KR20020080481A (ko)	2000-03-13	2002-10-23	하. 룬트벡 아크티에 셀스카브	시탈로프람의 제조 방법
TR200202155T2 (tr)	2000-03-14	2002-12-23	H. Lundbeck A/S	Sitalopramin preparasyon metodu
DE10190485T1 (de) *	2000-03-16	2002-03-21	Lundbeck & Co As H	Verfahren zur Herstellung von 5-Cyano-1-(4-fluorphenyl)-1,3-dihydroisobenzofuranen
AR032455A1 (es)	2000-05-12	2003-11-12	Lundbeck & Co As H	Metodo para la preparacion de citalopram, un intermediario empleado en el metodo, un metodo para la preparacion del intermediario empleado en el metodo y composicion farmaceutica antidepresiva
CA2383963A1 (en) *	2000-07-06	2002-01-17	Eva Bolzonella	Method for the preparation of citalopram
CA2354877C (en) *	2000-08-18	2006-05-02	H. Lundbeck A/S	Method for the preparation of citalopram
WO2001045483A2 (en) *	2000-12-22	2001-06-28	H. Lundbeck A/S	Method for the preparation of pure citalopram
JP2003519121A (ja) *	2000-12-28	2003-06-17	ハー・ルンドベック・アクチエゼルスカベット	純粋なシタロプラムの製造方法
EP1355897A1 (de)	2001-01-30	2003-10-29	Orion Corporation Fermion	Verfahren zur herstellung von 1-(3-dimethylaminopropyl)-1-(4-fluorphenyl)-1,3-dihydrobenzofuran-5-carbonitrile
GB0105627D0 (en) *	2001-03-07	2001-04-25	Cipla Ltd	Preparation of phthalanes
JP2005500256A (ja) *	2001-03-09	2005-01-06	ランバクシーラボラトリーズリミテッド	シタロプラム製造方法
US6967259B2 (en) *	2001-09-24	2005-11-22	Pharmachem Technologies Limited	Process for the preparation of Citalopram intermediate
US7148364B2 (en) *	2002-01-07	2006-12-12	Sun Pharmaceutical Industries	Process for the preparation of 1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-5-isobenzofuran carbonitrile
AR040970A1 (es)	2002-08-12	2005-04-27	Lundbeck & Co As H	Metodo para la separacion de intermediarios que pueden ser utilizados para la preparacion de escitalopram
WO2004085416A1 (en) *	2003-03-24	2004-10-07	Hetero Drugs Limited	Novel crystalline forms of (s)-citalopram oxalate
US7019153B2 (en)	2003-06-10	2006-03-28	Sun Pharmaceutical Industries Limited	Process for hydrogenolysis of [1-(3-dimethylamino)propyl)]-1-(4-fluorophenyl)-1,3-dihydro-5-halo-isobenzofuran acetamido-3-substituted-3-cephem-4-carboxylic acid
TWI339651B (en)	2004-02-12	2011-04-01	Lundbeck & Co As H	Method for the separation of intermediates which may be used for the preparation of escitalopram
ES2285972T1 (es)	2004-08-23	2007-12-01	Sun Pharmaceutical Industries Limited	Procedimiento de fabricacion de citalopram y enantiomeros.
TWI347942B (en) *	2005-06-22	2011-09-01	Lundbeck & Co As H	Crystalline base of escitalopram and orodispersible tablets comprising escitalopram base
US7834201B2 (en)	2005-06-22	2010-11-16	H. Lundbeck A/S	Crystalline base of escitalopram and orodispersible tablets comprising escitalopram base
EP2017271A1 (de)	2007-07-06	2009-01-21	Aurobindo Pharma Limited	Verfahren zur Herstellung von Escitalopram
CN114763343B (zh) *	2021-01-14	2026-02-10	浙江华海药业股份有限公司	一种西酞普兰或s-西酞普兰的纯化方法

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB1143703A (de) *	1965-03-18
GB1526331A (en) *	1976-01-14	1978-09-27	Kefalas As	Phthalanes
GB8419963D0 (en) *	1984-08-06	1984-09-12	Lundbeck & Co As H	Intermediate compound and method
GB8814057D0 (en) *	1988-06-14	1988-07-20	Lundbeck & Co As H	New enantiomers & their isolation
US5296507A (en) *	1990-09-06	1994-03-22	H.Lundbeck A/S	Treatment of cerbrovascular disorders
DK213290D0 (da) *	1990-09-06	1990-09-06	Lundbeck & Co As H	Treatment of cerebrovascular disorders
DE19626659A1 (de) *	1996-07-03	1998-01-08	Basf Ag	Verfahren zur Herstellung von Phthaliden
DE19627697A1 (de) *	1996-07-10	1998-01-15	Basf Ag	Verfahren zur Herstellung von Phthaliden
ES2148120T3 (es) *	1997-07-08	2002-01-16	Lundbeck & Co As H	Metodo para la preparacion de citalopram.
UA62985C2 (en) *	1997-11-10	2004-01-15	Lunnbeck As H	A method for the preparation of citalopram
EA002770B1 (ru) *	1997-11-11	2002-08-29	Х.Лундбекк А/С	Способ получения циталопрама
PL199423B1 (pl) *	1998-10-20	2008-09-30	Lundbeck & Co As H	Sposób wytwarzania citalopramu
IL143422A0 (en) *	1998-12-23	2002-04-21	Lundbeck & Co As H	Method for the preparation of 5-cyanophthalide
AR022329A1 (es) *	1999-01-29	2002-09-04	Lundbeck & Co As H	Metodo para la preparacion de 5-cianoftalida
DK1173431T4 (da) *	1999-04-14	2010-01-04	Lundbeck & Co As H	Fremgangsmåde til fremstilling af citalopram
ITMI991579A1 (it) *	1999-06-25	2001-01-15	Lundbeck & Co As H	Metodo per la preparazione di citalopram
GB2360281B (en) *	1999-10-25	2002-01-16	Lundbeck & Co As H	Method for the preparation of citalopram
AR026063A1 (es) *	1999-11-01	2002-12-26	Lundbeck & Co As H	Metodo para la preparacion de 5-carboxiftalida.
IES20010143A2 (en) *	2000-02-24	2001-07-25	Lundbeck & Co As H	Method for the preparation of citalopram
NL1017415C1 (nl) *	2000-02-24	2001-05-18	Lundbeck & Co As H	Werkwijze voor de bereiding van Citalopram.
CA2354877C (en) *	2000-08-18	2006-05-02	H. Lundbeck A/S	Method for the preparation of citalopram
WO2001045483A2 (en) *	2000-12-22	2001-06-28	H. Lundbeck A/S	Method for the preparation of pure citalopram
JP2003519121A (ja) *	2000-12-28	2003-06-17	ハー・ルンドベック・アクチエゼルスカベット	純粋なシタロプラムの製造方法

1999
- 1999-07-15 IT IT1999MI001581A patent/ITMI991581A1/it unknown
- 1999-11-22 CZ CZ2001320A patent/CZ292198B6/cs not_active IP Right Cessation
- 1999-11-22 HK HK03101234.1A patent/HK1049002B/zh not_active IP Right Cessation
- 1999-11-22 CA CA002475401A patent/CA2475401A1/en not_active Abandoned
- 1999-11-22 SK SK1840-2001A patent/SK285813B6/sk not_active IP Right Cessation
- 1999-11-22 GB GB0105182A patent/GB2357761B/en not_active Expired - Fee Related
- 1999-11-22 ES ES200150011A patent/ES2189699A1/es not_active Withdrawn
- 1999-11-22 EA EA200101072A patent/EA002560B1/ru not_active IP Right Cessation
- 1999-11-22 JP JP2000568457A patent/JP3447267B2/ja not_active Expired - Fee Related
- 1999-11-22 CA CA002290127A patent/CA2290127C/en not_active Expired - Fee Related
- 1999-11-22 NZ NZ514979A patent/NZ514979A/en not_active IP Right Cessation
- 1999-11-22 AU AU13745/00A patent/AU1374500A/en active Pending
- 1999-11-22 AU AU2001100440A patent/AU2001100440B4/en not_active Expired
- 1999-11-22 KR KR10-2001-7014053A patent/KR100491368B1/ko not_active Expired - Fee Related
- 1999-11-22 CH CH00308/01A patent/CH691305A5/de not_active IP Right Cessation
- 1999-11-22 SI SI9930276T patent/SI1159274T1/xx unknown
- 1999-11-22 DE DE19983487A patent/DE19983487C1/de not_active Expired - Fee Related
- 1999-11-22 GB GB0101504A patent/GB2354239B/en not_active Expired - Fee Related
- 1999-11-22 IL IL14595999A patent/IL145959A0/xx active IP Right Grant
- 1999-11-22 UA UA2001118041A patent/UA63034C2/uk unknown
- 1999-11-22 AT AT99968622T patent/ATE235478T1/de not_active IP Right Cessation
- 1999-11-22 DE DE69906389T patent/DE69906389T2/de not_active Expired - Lifetime
- 1999-11-22 MX MXPA01010989A patent/MXPA01010989A/es not_active IP Right Cessation
- 1999-11-22 PT PT99968622T patent/PT1159274E/pt unknown
- 1999-11-22 WO PCT/DK1999/000640 patent/WO2000013648A2/en not_active Ceased
- 1999-11-22 EP EP99968622A patent/EP1159274B1/de not_active Expired - Lifetime
- 1999-11-22 CN CNB998167517A patent/CN1140521C/zh not_active Expired - Fee Related
- 1999-11-22 PL PL346237A patent/PL205579B1/pl not_active IP Right Cessation
- 1999-11-22 CN CNA2003101187801A patent/CN1502616A/zh active Pending
- 1999-11-22 AT AT0904199A patent/AT409961B/de not_active IP Right Cessation
- 1999-11-22 HU HU0103235A patent/HUP0103235A3/hu unknown
- 1999-11-22 TR TR2001/03702T patent/TR200103702T2/xx unknown
- 1999-11-22 BR BRPI9917368-9A patent/BR9917368B1/pt not_active IP Right Cessation
- 1999-11-22 DK DK99968622T patent/DK1159274T3/da active
- 1999-11-22 ES ES99968622T patent/ES2194545T3/es not_active Expired - Lifetime
2000
- 2000-06-20 AR ARP000103055A patent/AR020863A1/es active IP Right Grant
2001
- 2001-01-15 DK DK200100060A patent/DK200100060A/da not_active Application Discontinuation
- 2001-01-19 NO NO20010319A patent/NO328542B1/no not_active IP Right Cessation
- 2001-01-24 SE SE0100193A patent/SE516690C2/sv not_active IP Right Cessation
- 2001-01-25 FI FI20010155A patent/FI108641B/fi not_active IP Right Cessation
- 2001-02-23 IS IS5861A patent/IS2343B/is unknown
- 2001-03-13 AT AT0018401U patent/AT4365U1/de not_active IP Right Cessation
- 2001-10-16 IL IL145959A patent/IL145959A/en not_active IP Right Cessation
- 2001-10-26 ZA ZA200108854A patent/ZA200108854B/xx unknown
- 2001-11-06 US US10/012,054 patent/US20020077353A1/en not_active Abandoned
- 2001-12-07 BG BG106191A patent/BG65574B1/bg unknown
2008
- 2008-12-08 US US12/329,750 patent/US20090088469A1/en not_active Abandoned

Also Published As

Publication number	Publication date
HUP0103235A3 (en)	2003-01-28
GB2354239B (en)	2001-06-06
BR9917368A (pt)	2002-03-05
CH691305A5 (de)	2001-06-29
NO328542B1 (no)	2010-03-15
NO20010319L (no)	2001-02-23
IL145959A0 (en)	2002-07-25
WO2000013648B1 (en)	2001-03-15
ZA200108854B (en)	2002-08-28
SI1159274T1 (en)	2003-10-31
CN1140521C (zh)	2004-03-03
ES2189699A1 (es)	2003-07-01
EP1159274A2 (de)	2001-12-05
GB2354239A (en)	2001-03-21
SE516690C2 (sv)	2002-02-12
AU2001100440A4 (en)	2001-11-01
BG65574B1 (bg)	2009-01-30
KR20020012204A (ko)	2002-02-15
DE69906389T2 (de)	2003-10-30
CN1502616A (zh)	2004-06-09
WO2000013648A8 (en)	2000-05-11
AT4365U1 (de)	2001-06-25
SE0100193D0 (sv)	2001-01-24
ITMI991581A0 (it)	1999-07-15
CZ2001320A3 (en)	2001-05-16
AU2001100440B4 (en)	2002-01-24
CA2475401A1 (en)	2000-12-25
CA2290127C (en)	2005-01-25
IS2343B (is)	2008-02-15
DE69906389D1 (de)	2003-04-30
PL205579B1 (pl)	2010-05-31
AR020863A1 (es)	2002-05-29
HUP0103235A2 (hu)	2002-01-28
UA63034C2 (en)	2004-01-15
AU1374500A (en)	2000-03-27
PL346237A1 (en)	2002-01-28
GB2357761A (en)	2001-07-04
AT409961B (de)	2002-12-27
WO2000013648A3 (en)	2000-07-13
KR100491368B1 (ko)	2005-05-24
EA200101072A1 (ru)	2002-02-28
IS5861A (is)	2001-02-23
ES2194545T3 (es)	2003-11-16
IL145959A (en)	2007-07-24
FI108641B (fi)	2002-02-28
PT1159274E (pt)	2003-08-29
ATA904199A (de)	2002-05-15
JP3447267B2 (ja)	2003-09-16
DK200100060A (da)	2001-04-10
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