ATE389645T1 - Verfahren zur herstellung von citalopram - Google Patents

Verfahren zur herstellung von citalopram

Info

Publication number: ATE389645T1
Authority: AT; Austria
Prior art keywords: producing citalopram; citalopram; producing
Prior art date: 2000-05-12

Application number

AT01931469T

Other languages

English (en)

Inventor

Hans Petersen

Robert Dancer

Original Assignee

Lundbeck & Co As H

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-05-12

Filing date

2001-05-10

Publication date

2008-04-15

2001-05-10 Application filed by Lundbeck & Co As H filed Critical Lundbeck & Co As H

2008-04-15 Application granted granted Critical

2008-04-15 Publication of ATE389645T1 publication Critical patent/ATE389645T1/de

Links

WSEQXVZVJXJVFP-UHFFFAOYSA-N 1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile Chemical compound O1CC2=CC(C#N)=CC=C2C1(CCCN(C)C)C1=CC=C(F)C=C1 WSEQXVZVJXJVFP-UHFFFAOYSA-N 0.000 title 1
229960001653 citalopram Drugs 0.000 title 1
238000004519 manufacturing process Methods 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/87—Benzo [c] furans; Hydrogenated benzo [c] furans
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/87—Benzo [c] furans; Hydrogenated benzo [c] furans
- C07D307/88—Benzo [c] furans; Hydrogenated benzo [c] furans with one oxygen atom directly attached in position 1 or 3

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Engineering & Computer Science (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Psychiatry (AREA)
Pain & Pain Management (AREA)
Bioinformatics & Cheminformatics (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Steroid Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Furan Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

AT01931469T 2000-05-12 2001-05-10 Verfahren zur herstellung von citalopram ATE389645T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DKPA200000783		2000-05-12

Publications (1)

Publication Number	Publication Date
ATE389645T1 true ATE389645T1 (de)	2008-04-15

Family

ID=8159493

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT01931469T ATE389645T1 (de)	2000-05-12	2001-05-10	Verfahren zur herstellung von citalopram

Country Status (29)

Country	Link
US (1)	US6660873B2 (de)
EP (1)	EP1296970B1 (de)
JP (1)	JP2003532721A (de)
CN (1)	CN100422166C (de)
AR (1)	AR032455A1 (de)
AT (1)	ATE389645T1 (de)
AU (2)	AU5823901A (de)
BG (1)	BG65820B1 (de)
BR (1)	BR0110996A (de)
CA (1)	CA2408292C (de)
CZ (1)	CZ20024065A3 (de)
DE (1)	DE60133280T2 (de)
DK (1)	DK1296970T3 (de)
EA (1)	EA005674B1 (de)
ES (1)	ES2301541T3 (de)
HR (1)	HRP20020881A2 (de)
HU (1)	HUP0301942A2 (de)
IL (2)	IL152645A0 (de)
IS (1)	IS2586B (de)
MX (1)	MXPA02011125A (de)
NO (1)	NO327963B1 (de)
NZ (1)	NZ522475A (de)
PL (1)	PL358144A1 (de)
PT (1)	PT1296970E (de)
SI (1)	SI1296970T1 (de)
SK (1)	SK287035B6 (de)
UA (1)	UA72039C2 (de)
WO (1)	WO2001085712A1 (de)
ZA (1)	ZA200208973B (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DK1173431T4 (da)	1999-04-14	2010-01-04	Lundbeck & Co As H	Fremgangsmåde til fremstilling af citalopram
US6310222B1 (en) *	1999-11-01	2001-10-30	Sumika Fine Chemicals Co., Ltd.	Production method of 5-phthalancarbonitrile compound, intermediate therefor and production method of the intermediate
US6433196B1 (en) *	2000-02-17	2002-08-13	Sumika Fine Chemicals Co., Ltd.	Production method of citalopram, intermediate therefor and production method of the intermediate
IES20010157A2 (en)	2000-03-03	2002-03-06	Lundbeck & Co As H	Method for the preparation of citalopram
KR20020080485A (ko)	2000-03-13	2002-10-23	하. 룬트벡 아크티에 셀스카브	5-치환 1-(4-플루오로페닐)-1,3-디히드로이소벤조푸란의단계적 알킬화
NL1017500C1 (nl)	2000-03-13	2001-04-26	Lundbeck & Co As H	Werkwijze voor de bereiding van Citalopram.
AR032455A1 (es)	2000-05-12	2003-11-12	Lundbeck & Co As H	Metodo para la preparacion de citalopram, un intermediario empleado en el metodo, un metodo para la preparacion del intermediario empleado en el metodo y composicion farmaceutica antidepresiva
IN192057B (de) *	2001-07-19	2004-02-14	Ranbaxy Lab Ltd
AU2003223105A1 (en) *	2003-03-24	2004-10-18	Hetero Drugs Limited	Novel crystalline forms of (s)-citalopram oxalate
EP1678122A4 (de) *	2003-10-28	2007-05-23	Wockhardt Ltd	Verbessertes verfahren zur herstellung von citalopram-hydrobromid
US20050143350A1 (en) *	2003-11-19	2005-06-30	Seed John C.	Combination drug therapy to treat obesity
EP1797060A2 (de)	2004-08-23	2007-06-20	Sun Pharmaceutical Industries Limited	Verfahren zur herstellung von citalopram und enantiomeren

Family Cites Families (40)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB1143703A (de)	1965-03-18
GB1526331A (en) *	1976-01-14	1978-09-27	Kefalas As	Phthalanes
GB8419963D0 (en)	1984-08-06	1984-09-12	Lundbeck & Co As H	Intermediate compound and method
GB8814057D0 (en)	1988-06-14	1988-07-20	Lundbeck & Co As H	New enantiomers & their isolation
US5296507A (en)	1990-09-06	1994-03-22	H.Lundbeck A/S	Treatment of cerbrovascular disorders
DE19626659A1 (de)	1996-07-03	1998-01-08	Basf Ag	Verfahren zur Herstellung von Phthaliden
DE19627697A1 (de)	1996-07-10	1998-01-15	Basf Ag	Verfahren zur Herstellung von Phthaliden
SK283309B6 (sk)	1997-07-08	2003-05-02	H. Lundbeck A/S	Spôsob výroby citalopramu a medziprodukty
UA62985C2 (en) *	1997-11-10	2004-01-15	Lunnbeck As H	A method for the preparation of citalopram
DK1042310T3 (da)	1997-11-11	2002-12-02	Lundbeck & Co As H	Fremgangsmåde til fremstilling af citalopram
ES2189502T3 (es)	1998-10-20	2003-07-01	Lundbeck & Co As H	Metodo para la prevencion de citalopram.
IL143422A0 (en)	1998-12-23	2002-04-21	Lundbeck & Co As H	Method for the preparation of 5-cyanophthalide
AR022329A1 (es)	1999-01-29	2002-09-04	Lundbeck & Co As H	Metodo para la preparacion de 5-cianoftalida
DK1173431T4 (da)	1999-04-14	2010-01-04	Lundbeck & Co As H	Fremgangsmåde til fremstilling af citalopram
ITMI991581A1 (it)	1999-06-25	2001-01-15	Lundbeck & Co As H	Metodo per la preparazione di citalopram
ITMI991579A1 (it)	1999-06-25	2001-01-15	Lundbeck & Co As H	Metodo per la preparazione di citalopram
ITMI991486A1 (it)	1999-07-06	2001-01-06	Vis Farmaceutici S P A	Processo per la sintesi di citalopram
CH692421A5 (de)	1999-10-25	2002-06-14	Lundbeck & Co As H	Verfahren zur Herstellung von Citalopram.
AR026063A1 (es)	1999-11-01	2002-12-26	Lundbeck & Co As H	Metodo para la preparacion de 5-carboxiftalida.
US6310222B1 (en)	1999-11-01	2001-10-30	Sumika Fine Chemicals Co., Ltd.	Production method of 5-phthalancarbonitrile compound, intermediate therefor and production method of the intermediate
JP2003519136A (ja)	1999-12-28	2003-06-17	ハー・ルンドベック・アクチエゼルスカベット	シタロプラムの製造方法
DK1246813T3 (da)	1999-12-30	2004-03-01	Lundbeck & Co As H	Fremgangsmåde til fremstilling af Citalopram
AU3033700A (en)	2000-01-14	2001-07-24	H. Lundbeck A/S	Method for the preparation of 5-cyanophthalide
IT1317729B1 (it)	2000-01-18	2003-07-15	Norpharma S P A	Procedimento per la preparazione della 5-carbossiftalide.
US6433196B1 (en)	2000-02-17	2002-08-13	Sumika Fine Chemicals Co., Ltd.	Production method of citalopram, intermediate therefor and production method of the intermediate
FR2805812A1 (fr)	2000-02-24	2001-09-07	Lundbeck & Co As H	Procede de preparation du citalopram
IES20010143A2 (en)	2000-02-24	2001-07-25	Lundbeck & Co As H	Method for the preparation of citalopram
IES20010157A2 (en)	2000-03-03	2002-03-06	Lundbeck & Co As H	Method for the preparation of citalopram
GB0005477D0 (en)	2000-03-07	2000-04-26	Resolution Chemicals Limited	Process for the preparation of citalopram
KR20020080485A (ko)	2000-03-13	2002-10-23	하. 룬트벡 아크티에 셀스카브	5-치환 1-(4-플루오로페닐)-1,3-디히드로이소벤조푸란의단계적 알킬화
GB2357762B (en)	2000-03-13	2002-01-30	Lundbeck & Co As H	Crystalline base of citalopram
AU2001242298A1 (en)	2000-03-13	2001-09-24	H Lunbeck A/S	Method for the preparation of citalopram
NL1017500C1 (nl)	2000-03-13	2001-04-26	Lundbeck & Co As H	Werkwijze voor de bereiding van Citalopram.
ES2214400T3 (es)	2000-03-14	2004-09-16	H. Lundbeck A/S	Metodo para la preparacion de citalopram.
DE10190485T1 (de)	2000-03-16	2002-03-21	Lundbeck & Co As H	Verfahren zur Herstellung von 5-Cyano-1-(4-fluorphenyl)-1,3-dihydroisobenzofuranen
AR032455A1 (es)	2000-05-12	2003-11-12	Lundbeck & Co As H	Metodo para la preparacion de citalopram, un intermediario empleado en el metodo, un metodo para la preparacion del intermediario empleado en el metodo y composicion farmaceutica antidepresiva
WO2002004435A1 (en)	2000-07-06	2002-01-17	H. Lundbeck A/S	Method for the preparation of citalopram
CA2354877C (en)	2000-08-18	2006-05-02	H. Lundbeck A/S	Method for the preparation of citalopram
CA2360303C (en)	2000-12-22	2003-08-12	Marco Villa	Process for the preparation of pure citalopram
SK284418B6 (sk)	2000-12-28	2005-04-01	H. Lundbeck A/S	Spôsob výroby citalopramu

2001
- 2001-05-07 AR ARP010102152A patent/AR032455A1/es active IP Right Grant
- 2001-05-10 AU AU5823901A patent/AU5823901A/xx active Pending
- 2001-05-10 CZ CZ20024065A patent/CZ20024065A3/cs unknown
- 2001-05-10 NZ NZ522475A patent/NZ522475A/en unknown
- 2001-05-10 EP EP01931469A patent/EP1296970B1/de not_active Expired - Lifetime
- 2001-05-10 AT AT01931469T patent/ATE389645T1/de not_active IP Right Cessation
- 2001-05-10 JP JP2001582313A patent/JP2003532721A/ja not_active Withdrawn
- 2001-05-10 EA EA200201211A patent/EA005674B1/ru not_active IP Right Cessation
- 2001-05-10 AU AU2001258239A patent/AU2001258239B2/en not_active Ceased
- 2001-05-10 WO PCT/DK2001/000333 patent/WO2001085712A1/en not_active Ceased
- 2001-05-10 BR BR0110996-0A patent/BR0110996A/pt not_active Application Discontinuation
- 2001-05-10 PT PT01931469T patent/PT1296970E/pt unknown
- 2001-05-10 PL PL01358144A patent/PL358144A1/xx unknown
- 2001-05-10 CA CA002408292A patent/CA2408292C/en not_active Expired - Fee Related
- 2001-05-10 SI SI200130831T patent/SI1296970T1/sl unknown
- 2001-05-10 SK SK1754-2002A patent/SK287035B6/sk not_active IP Right Cessation
- 2001-05-10 ES ES01931469T patent/ES2301541T3/es not_active Expired - Lifetime
- 2001-05-10 IL IL15264501A patent/IL152645A0/xx unknown
- 2001-05-10 DE DE60133280T patent/DE60133280T2/de not_active Expired - Fee Related
- 2001-05-10 MX MXPA02011125A patent/MXPA02011125A/es active IP Right Grant
- 2001-05-10 HR HRP20020881 patent/HRP20020881A2/hr not_active Application Discontinuation
- 2001-05-10 CN CNB018125859A patent/CN100422166C/zh not_active Expired - Fee Related
- 2001-05-10 DK DK01931469T patent/DK1296970T3/da active
- 2001-05-10 HU HU0301942A patent/HUP0301942A2/hu unknown
- 2001-10-05 UA UA2002118821A patent/UA72039C2/uk unknown
2002
- 2002-10-31 IS IS6605A patent/IS2586B/is unknown
- 2002-11-04 IL IL152645A patent/IL152645A/en not_active IP Right Cessation
- 2002-11-05 ZA ZA200208973A patent/ZA200208973B/en unknown
- 2002-11-08 US US10/291,174 patent/US6660873B2/en not_active Expired - Fee Related
- 2002-11-12 NO NO20025423A patent/NO327963B1/no not_active IP Right Cessation
- 2002-12-03 BG BG107349A patent/BG65820B1/bg unknown

Also Published As

Publication number	Publication date
PL358144A1 (en)	2004-08-09
SK17542002A3 (sk)	2003-04-01
HK1056171A1 (zh)	2004-02-06
IS2586B (is)	2010-02-15
NO20025423L (no)	2002-11-12
IL152645A (en)	2009-12-24
IL152645A0 (en)	2003-06-24
CN1441795A (zh)	2003-09-10
US6660873B2 (en)	2003-12-09
AU5823901A (en)	2001-11-20
US20030134895A1 (en)	2003-07-17
HRP20020881A2 (en)	2004-12-31
CN100422166C (zh)	2008-10-01
EP1296970A1 (de)	2003-04-02
BG65820B1 (bg)	2010-01-29
EP1296970B1 (de)	2008-03-19
WO2001085712A1 (en)	2001-11-15
SI1296970T1 (sl)	2008-08-31
NO327963B1 (no)	2009-10-26
PT1296970E (pt)	2008-06-11
DK1296970T3 (da)	2008-07-14
CA2408292C (en)	2009-11-10
NZ522475A (en)	2004-09-24
AU2001258239B2 (en)	2005-12-08
UA72039C2 (en)	2005-01-17
EA200201211A1 (ru)	2003-04-24
BG107349A (bg)	2003-09-30
IS6605A (is)	2002-10-31
SK287035B6 (sk)	2009-10-07
NO20025423D0 (no)	2002-11-12
CA2408292A1 (en)	2001-11-15
BR0110996A (pt)	2003-03-18
ES2301541T3 (es)	2008-07-01
ZA200208973B (en)	2003-11-05
CZ20024065A3 (cs)	2003-03-12
AR032455A1 (es)	2003-11-12
DE60133280T2 (de)	2009-04-16
HUP0301942A2 (hu)	2003-09-29
MXPA02011125A (es)	2003-03-10
EA005674B1 (ru)	2005-04-28
DE60133280D1 (de)	2008-04-30
JP2003532721A (ja)	2003-11-05

Legal Events

Date

Code

Title

Description

2008-09-15

UEP

Publication of translation of european patent specification

Ref document number: 1296970

Country of ref document: EP

2011-02-15

REN

Ceased due to non-payment of the annual fee

Publication	Publication Date	Title
DE69907037T2 (de)	2004-01-29	Verfahren zur herstellung von citalopram
ATE213237T1 (de)	2002-02-15	Verfahren zur herstellung von citalopram
ATE235478T1 (de)	2003-04-15	Verfahren zur herstellung von citalopram
ATE281447T1 (de)	2004-11-15	Verfahren zur herstellung von citalopram
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