ATE389645T1 - Verfahren zur herstellung von citalopram - Google Patents

Verfahren zur herstellung von citalopram

Info

Publication number
ATE389645T1
ATE389645T1 AT01931469T AT01931469T ATE389645T1 AT E389645 T1 ATE389645 T1 AT E389645T1 AT 01931469 T AT01931469 T AT 01931469T AT 01931469 T AT01931469 T AT 01931469T AT E389645 T1 ATE389645 T1 AT E389645T1
Authority
AT
Austria
Prior art keywords
producing citalopram
citalopram
producing
Prior art date
Application number
AT01931469T
Other languages
English (en)
Inventor
Hans Petersen
Robert Dancer
Original Assignee
Lundbeck & Co As H
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lundbeck & Co As H filed Critical Lundbeck & Co As H
Application granted granted Critical
Publication of ATE389645T1 publication Critical patent/ATE389645T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/87—Benzo [c] furans; Hydrogenated benzo [c] furans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/87—Benzo [c] furans; Hydrogenated benzo [c] furans
    • C07D307/88—Benzo [c] furans; Hydrogenated benzo [c] furans with one oxygen atom directly attached in position 1 or 3

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Furan Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
AT01931469T 2000-05-12 2001-05-10 Verfahren zur herstellung von citalopram ATE389645T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DKPA200000783 2000-05-12

Publications (1)

Publication Number Publication Date
ATE389645T1 true ATE389645T1 (de) 2008-04-15

Family

ID=8159493

Family Applications (1)

Application Number Title Priority Date Filing Date
AT01931469T ATE389645T1 (de) 2000-05-12 2001-05-10 Verfahren zur herstellung von citalopram

Country Status (29)

Country Link
US (1) US6660873B2 (de)
EP (1) EP1296970B1 (de)
JP (1) JP2003532721A (de)
CN (1) CN100422166C (de)
AR (1) AR032455A1 (de)
AT (1) ATE389645T1 (de)
AU (2) AU5823901A (de)
BG (1) BG65820B1 (de)
BR (1) BR0110996A (de)
CA (1) CA2408292C (de)
CZ (1) CZ20024065A3 (de)
DE (1) DE60133280T2 (de)
DK (1) DK1296970T3 (de)
EA (1) EA005674B1 (de)
ES (1) ES2301541T3 (de)
HR (1) HRP20020881A2 (de)
HU (1) HUP0301942A2 (de)
IL (2) IL152645A0 (de)
IS (1) IS2586B (de)
MX (1) MXPA02011125A (de)
NO (1) NO327963B1 (de)
NZ (1) NZ522475A (de)
PL (1) PL358144A1 (de)
PT (1) PT1296970E (de)
SI (1) SI1296970T1 (de)
SK (1) SK287035B6 (de)
UA (1) UA72039C2 (de)
WO (1) WO2001085712A1 (de)
ZA (1) ZA200208973B (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ514671A (en) 1999-04-14 2003-10-31 H Method for the preparation of citalopram
US6310222B1 (en) * 1999-11-01 2001-10-30 Sumika Fine Chemicals Co., Ltd. Production method of 5-phthalancarbonitrile compound, intermediate therefor and production method of the intermediate
US6433196B1 (en) * 2000-02-17 2002-08-13 Sumika Fine Chemicals Co., Ltd. Production method of citalopram, intermediate therefor and production method of the intermediate
NL1017417C1 (nl) 2000-03-03 2001-03-16 Lundbeck & Co As H Werkwijze voor de bereiding van Citalopram.
NL1017500C1 (nl) 2000-03-13 2001-04-26 Lundbeck & Co As H Werkwijze voor de bereiding van Citalopram.
CZ20023100A3 (cs) * 2000-03-13 2003-02-12 H. Lundbeck A/S Způsob výroby citalopramu
AR032455A1 (es) 2000-05-12 2003-11-12 Lundbeck & Co As H Metodo para la preparacion de citalopram, un intermediario empleado en el metodo, un metodo para la preparacion del intermediario empleado en el metodo y composicion farmaceutica antidepresiva
IN192057B (de) * 2001-07-19 2004-02-14 Ranbaxy Lab Ltd
TR200504022T1 (tr) * 2003-03-24 2006-08-21 Hetero Drugs Limited (S)-sitalopram oksalatın yeni sıvı kristal formları.
AU2003278409A1 (en) * 2003-10-28 2005-05-19 Krishnaji Upadhye Bhargav Improved process for the manufacture of citalopram hydrobromide
US20050143350A1 (en) * 2003-11-19 2005-06-30 Seed John C. Combination drug therapy to treat obesity
KR101166280B1 (ko) 2004-08-23 2013-11-27 썬 파마 글로벌 에프제트이 시탈로프램 및 에난티오머의 제조 방법

Family Cites Families (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1143703A (de) 1965-03-18
GB1526331A (en) * 1976-01-14 1978-09-27 Kefalas As Phthalanes
GB8419963D0 (en) 1984-08-06 1984-09-12 Lundbeck & Co As H Intermediate compound and method
GB8814057D0 (en) 1988-06-14 1988-07-20 Lundbeck & Co As H New enantiomers & their isolation
US5296507A (en) 1990-09-06 1994-03-22 H.Lundbeck A/S Treatment of cerbrovascular disorders
DE19626659A1 (de) 1996-07-03 1998-01-08 Basf Ag Verfahren zur Herstellung von Phthaliden
DE19627697A1 (de) 1996-07-10 1998-01-15 Basf Ag Verfahren zur Herstellung von Phthaliden
TR200000066T2 (tr) 1997-07-08 2000-11-21 H. Lundbeck A/S Sitalopram hazırlanması için yöntem.
UA62985C2 (en) * 1997-11-10 2004-01-15 Lunnbeck As H A method for the preparation of citalopram
ES2149734T3 (es) * 1997-11-11 2003-02-16 Lundbeck & Co As H Metodo para la preparacion de citalopram.
PL199423B1 (pl) 1998-10-20 2008-09-30 Lundbeck & Co As H Sposób wytwarzania citalopramu
CN1149208C (zh) 1998-12-23 2004-05-12 H.隆德贝克有限公司 制备5-氰基2-苯并[c]呋喃酮的方法
AR022329A1 (es) 1999-01-29 2002-09-04 Lundbeck & Co As H Metodo para la preparacion de 5-cianoftalida
NZ514671A (en) 1999-04-14 2003-10-31 H Method for the preparation of citalopram
ITMI991581A1 (it) 1999-06-25 2001-01-15 Lundbeck & Co As H Metodo per la preparazione di citalopram
ITMI991579A1 (it) 1999-06-25 2001-01-15 Lundbeck & Co As H Metodo per la preparazione di citalopram
ITMI991486A1 (it) 1999-07-06 2001-01-06 Vis Farmaceutici S P A Processo per la sintesi di citalopram
CH692298A5 (de) 1999-10-25 2002-04-30 Lundbeck & Co As H Verfahren zur Herstellung von Zwischenstufen für die Citalopramsynthese sowie zur Herstellung von Escitalopram.
AR026063A1 (es) 1999-11-01 2002-12-26 Lundbeck & Co As H Metodo para la preparacion de 5-carboxiftalida.
US6310222B1 (en) 1999-11-01 2001-10-30 Sumika Fine Chemicals Co., Ltd. Production method of 5-phthalancarbonitrile compound, intermediate therefor and production method of the intermediate
EA004742B1 (ru) 1999-12-28 2004-08-26 Х.Лундбекк А/С Способ получения циталопрама
WO2001049672A1 (en) 1999-12-30 2001-07-12 H. Lundbeck A/S Method for the preparation of citalopram
TR200201783T2 (tr) 2000-01-14 2002-12-23 H. Lundbeck A/S 5-Siyanofatalid hazırlamak için yöntem
IT1317729B1 (it) 2000-01-18 2003-07-15 Norpharma S P A Procedimento per la preparazione della 5-carbossiftalide.
US6433196B1 (en) 2000-02-17 2002-08-13 Sumika Fine Chemicals Co., Ltd. Production method of citalopram, intermediate therefor and production method of the intermediate
IES20010143A2 (en) 2000-02-24 2001-07-25 Lundbeck & Co As H Method for the preparation of citalopram
NL1017415C1 (nl) 2000-02-24 2001-05-18 Lundbeck & Co As H Werkwijze voor de bereiding van Citalopram.
NL1017417C1 (nl) 2000-03-03 2001-03-16 Lundbeck & Co As H Werkwijze voor de bereiding van Citalopram.
GB0005477D0 (en) 2000-03-07 2000-04-26 Resolution Chemicals Limited Process for the preparation of citalopram
GB2357762B (en) 2000-03-13 2002-01-30 Lundbeck & Co As H Crystalline base of citalopram
NL1017500C1 (nl) 2000-03-13 2001-04-26 Lundbeck & Co As H Werkwijze voor de bereiding van Citalopram.
CZ20023100A3 (cs) 2000-03-13 2003-02-12 H. Lundbeck A/S Způsob výroby citalopramu
KR20020080481A (ko) 2000-03-13 2002-10-23 하. 룬트벡 아크티에 셀스카브 시탈로프람의 제조 방법
SK14512002A3 (sk) 2000-03-14 2003-03-04 H. Lundbeck A/S Spôsob výroby citalopramu, medziprodukt a citalopram výrobený týmto spôsobom
EP1274699A1 (de) 2000-03-16 2003-01-15 H. Lundbeck A/S Verfahren zur herstellung von 5-cyano-1-(4-fluorophenyl)-1,3-dihydroisobenzofuranen
AR032455A1 (es) 2000-05-12 2003-11-12 Lundbeck & Co As H Metodo para la preparacion de citalopram, un intermediario empleado en el metodo, un metodo para la preparacion del intermediario empleado en el metodo y composicion farmaceutica antidepresiva
BR0106976A (pt) 2000-07-06 2002-07-23 Lundbeck & Co As H Método para a preparação de citalopram
IL144817A0 (en) 2000-08-18 2002-06-30 Lundbeck & Co As H Method for the preparation of citalopram
JP3798982B2 (ja) 2000-12-22 2006-07-19 ハー・ルンドベック・アクチエゼルスカベット 純粋なシタロプラムの製造方法
CA2359810C (en) 2000-12-28 2002-11-05 H. Lundbeck A/S Process for the preparation of pure citalopram

Also Published As

Publication number Publication date
ES2301541T3 (es) 2008-07-01
NO20025423L (no) 2002-11-12
IS6605A (is) 2002-10-31
CN1441795A (zh) 2003-09-10
EP1296970A1 (de) 2003-04-02
EP1296970B1 (de) 2008-03-19
HRP20020881A2 (en) 2004-12-31
IS2586B (is) 2010-02-15
DE60133280T2 (de) 2009-04-16
BG107349A (bg) 2003-09-30
NO327963B1 (no) 2009-10-26
HK1056171A1 (zh) 2004-02-06
NO20025423D0 (no) 2002-11-12
CN100422166C (zh) 2008-10-01
MXPA02011125A (es) 2003-03-10
JP2003532721A (ja) 2003-11-05
ZA200208973B (en) 2003-11-05
UA72039C2 (en) 2005-01-17
CA2408292A1 (en) 2001-11-15
US20030134895A1 (en) 2003-07-17
SK287035B6 (sk) 2009-10-07
NZ522475A (en) 2004-09-24
PT1296970E (pt) 2008-06-11
AU2001258239B2 (en) 2005-12-08
EA005674B1 (ru) 2005-04-28
AU5823901A (en) 2001-11-20
CA2408292C (en) 2009-11-10
EA200201211A1 (ru) 2003-04-24
DE60133280D1 (de) 2008-04-30
AR032455A1 (es) 2003-11-12
PL358144A1 (en) 2004-08-09
HUP0301942A2 (hu) 2003-09-29
IL152645A (en) 2009-12-24
BG65820B1 (bg) 2010-01-29
IL152645A0 (en) 2003-06-24
SI1296970T1 (sl) 2008-08-31
BR0110996A (pt) 2003-03-18
SK17542002A3 (sk) 2003-04-01
CZ20024065A3 (cs) 2003-03-12
WO2001085712A1 (en) 2001-11-15
US6660873B2 (en) 2003-12-09
DK1296970T3 (da) 2008-07-14

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