ATE109796T1 - Gewebeinhibitor für metalloproteasen (timp-2). - Google Patents

Gewebeinhibitor für metalloproteasen (timp-2).

Info

Publication number
ATE109796T1
ATE109796T1 AT90870075T AT90870075T ATE109796T1 AT E109796 T1 ATE109796 T1 AT E109796T1 AT 90870075 T AT90870075 T AT 90870075T AT 90870075 T AT90870075 T AT 90870075T AT E109796 T1 ATE109796 T1 AT E109796T1
Authority
AT
Austria
Prior art keywords
follows
tissue inhibitor
collagenase
amino acid
timp
Prior art date
Application number
AT90870075T
Other languages
English (en)
Inventor
Gregory Isaac Goldberg
Original Assignee
Univ Washington
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Washington filed Critical Univ Washington
Application granted granted Critical
Publication of ATE109796T1 publication Critical patent/ATE109796T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81—Protease inhibitors
    • C07K14/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
    • C07K14/8146—Metalloprotease (E.C. 3.4.24) inhibitors, e.g. tissue inhibitor of metallo proteinase, TIMP

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AT90870075T 1989-05-26 1990-05-21 Gewebeinhibitor für metalloproteasen (timp-2). ATE109796T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US35804389A 1989-05-26 1989-05-26

Publications (1)

Publication Number Publication Date
ATE109796T1 true ATE109796T1 (de) 1994-08-15

Family

ID=23408062

Family Applications (1)

Application Number Title Priority Date Filing Date
AT90870075T ATE109796T1 (de) 1989-05-26 1990-05-21 Gewebeinhibitor für metalloproteasen (timp-2).

Country Status (5)

Country Link
EP (1) EP0404750B1 (de)
AT (1) ATE109796T1 (de)
DE (1) DE69011433T2 (de)
DK (1) DK0404750T3 (de)
ES (1) ES2060134T3 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU634533B2 (en) * 1989-03-21 1993-02-25 United States of America, as represented by the Secretary, U.S. Department of Commerce, The Matrix metalloproteinase inhibitor peptides
US5714465A (en) 1989-05-19 1998-02-03 Amgen Inc. Method of inhibiting tumor cell dissemination with a metalloproteinase inhibitor
JP2877509B2 (ja) * 1989-05-19 1999-03-31 アムジエン・インコーポレーテツド メタロプロテイナーゼ阻害剤
US6022948A (en) 1996-09-17 2000-02-08 Washington University Method of cell surface activation and inhibition
JP2001525669A (ja) * 1997-05-12 2001-12-11 ネーデルランセ オルハニサチエ フォール トゥーヘパスト−ナツールウェーテンシャッペルック オンデルズク テーエヌオー 細胞遊走の阻害のための方法および構築物
AU2094101A (en) * 1999-12-13 2001-06-18 Duanqing Pei Leukolysin/mmp25/mt6-mmp
US7247704B2 (en) 2000-12-18 2007-07-24 Arriva Pharmaceuticals, Inc. Multifunctional protease inhibitors and their use in treatment of disease
KR101363455B1 (ko) * 2011-09-09 2014-02-21 (주)케어젠 매트릭스 메탈로프로테아제 활성 억제 펩타이드 및 이의 용도

Also Published As

Publication number Publication date
DK0404750T3 (da) 1994-10-03
DE69011433T2 (de) 1995-04-06
ES2060134T3 (es) 1994-11-16
EP0404750A1 (de) 1990-12-27
DE69011433D1 (de) 1994-09-15
EP0404750B1 (de) 1994-08-10

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee