ATE113050T1 - Cephalosporine, verfahren zu ihrer herstellung und pharmazeutische präparate. - Google Patents

Cephalosporine, verfahren zu ihrer herstellung und pharmazeutische präparate.

Info

Publication number: ATE113050T1
Authority: AT; Austria
Prior art keywords: group; benzene ring; optionally substituted; processes; groups
Prior art date: 1986-11-21

Application number

AT87309852T

Other languages

English (en)

Inventor

Alain Michel Bertrandie

Thomas Geoffrey Colerick Bird

Frederic Henry Jung

Original Assignee

Ici Pharma

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1986-11-21

Filing date

1987-11-06

Publication date

1994-11-15

1987-11-06 Application filed by Ici Pharma filed Critical Ici Pharma

1994-11-15 Application granted granted Critical

1994-11-15 Publication of ATE113050T1 publication Critical patent/ATE113050T1/de

Links

229930186147 Cephalosporin Natural products 0.000 title abstract 2
229940124587 cephalosporin Drugs 0.000 title abstract 2
238000000034 method Methods 0.000 title abstract 2
HOKIDJSKDBPKTQ-GLXFQSAKSA-N cephalosporin C Chemical compound S1CC(COC(=O)C)=C(C(O)=O)N2C(=O)[C@@H](NC(=O)CCC[C@@H](N)C(O)=O)[C@@H]12 HOKIDJSKDBPKTQ-GLXFQSAKSA-N 0.000 title 1
238000004519 manufacturing process Methods 0.000 title 1
239000000825 pharmaceutical preparation Substances 0.000 title 1
-1 Cephalosporin compounds Chemical class 0.000 abstract 3
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 3
QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical group [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 2
150000002148 esters Chemical class 0.000 abstract 2
239000001257 hydrogen Substances 0.000 abstract 2
229910052739 hydrogen Inorganic materials 0.000 abstract 2
125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 2
238000001727 in vivo Methods 0.000 abstract 2
239000001301 oxygen Chemical group 0.000 abstract 2
229910052760 oxygen Inorganic materials 0.000 abstract 2
125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 1
125000002373 5 membered heterocyclic group Chemical group 0.000 abstract 1
125000004070 6 membered heterocyclic group Chemical group 0.000 abstract 1
NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical group [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 abstract 1
239000005864 Sulphur Chemical group 0.000 abstract 1
125000003342 alkenyl group Chemical group 0.000 abstract 1
239000003242 anti bacterial agent Substances 0.000 abstract 1
125000001951 carbamoylamino group Chemical group C(N)(=O)N* 0.000 abstract 1
125000001589 carboacyl group Chemical group 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
125000005842 heteroatom Chemical group 0.000 abstract 1
239000000543 intermediate Substances 0.000 abstract 1
125000005647 linker group Chemical group 0.000 abstract 1
125000001624 naphthyl group Chemical group 0.000 abstract 1
IJGRMHOSHXDMSA-UHFFFAOYSA-N nitrogen Substances N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 abstract 1
229910052757 nitrogen Inorganic materials 0.000 abstract 1
QJGQUHMNIGDVPM-UHFFFAOYSA-N nitrogen group Chemical group [N] QJGQUHMNIGDVPM-UHFFFAOYSA-N 0.000 abstract 1
125000001424 substituent group Chemical group 0.000 abstract 1
125000000547 substituted alkyl group Chemical group 0.000 abstract 1
125000005156 substituted alkylene group Chemical group 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
- A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
- A61K31/545—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents

Landscapes

Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Chemical & Material Sciences (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
Epidemiology (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
Cephalosporin Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

AT87309852T 1986-11-21 1987-11-06 Cephalosporine, verfahren zu ihrer herstellung und pharmazeutische präparate. ATE113050T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
EP86402592		1986-11-21

Publications (1)

Publication Number	Publication Date
ATE113050T1 true ATE113050T1 (de)	1994-11-15

Family

ID=8196360

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT87309852T ATE113050T1 (de)	1986-11-21	1987-11-06	Cephalosporine, verfahren zu ihrer herstellung und pharmazeutische präparate.

Country Status (4)

Country	Link
US (2)	US5114933A (de)
JP (1)	JPS63301887A (de)
AT (1)	ATE113050T1 (de)
DE (1)	DE3750673T2 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5262410A (en) *	1986-12-23	1993-11-16	Ici Pharma	3-heterocyclic thiomethyl cephalosporins
US5244890A (en) *	1988-06-06	1993-09-14	Fujisawa Pharmaceutical Co., Ltd.	Cephem compounds
JPH0699443B2 (ja) *	1989-09-29	1994-12-07	ファイザー製薬株式会社	セファロスポリン化合物
US5338843A (en) *	1992-01-30	1994-08-16	Becton, Dickinson And Company	Fluorogenic and chromogenic β-lactamase substrates
CN103649097A (zh) *	2011-05-02	2014-03-19	佐蒂斯有限责任公司	用作抗菌剂的新型头孢菌素类

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
NZ198350A (en) *	1980-09-25	1985-02-28	Toyama Chemical Co Ltd	Cephalosporins and intermediates;pharmaceutical compositions
GB8413152D0 (en) *	1983-06-03	1984-06-27	Ici Pharma	Cephalosporin derivatives
JPS6064986A (ja) *	1983-09-20	1985-04-13	Toyama Chem Co Ltd	セファロスポリン類の製造法
DE3581891D1 (de) *	1984-11-12	1991-04-04	Banyu Pharma Co Ltd	Cephalosporinderivate.
DE3585434D1 (de) *	1984-12-27	1992-04-02	Banyu Pharma Co Ltd	Cephalosporinverbindungen.
JPS6251688A (ja) *	1985-08-30	1987-03-06	Taito Pfizer Kk	新規なセフアロスポリン化合物
JPH064643B2 (ja) *	1985-12-20	1994-01-19	ファイザー製薬株式会社	セフアロスポリン化合物
JPS62209082A (ja) *	1986-03-11	1987-09-14	Banyu Pharmaceut Co Ltd	セフアロスポリン誘導体
US4814328A (en) *	1986-03-19	1989-03-21	Banyu Pharmaceutical Co., Ltd.	Cephalosporin derivatives, and antibacterial agents
EP0241901B1 (de) *	1986-04-14	1994-08-24	Banyu Pharmaceutical Co., Ltd.	Cephalosporinderivate, Verfahren zu ihrer Herstellung und antibakterielle Präparate
JPH083951B2 (ja) *	1987-07-31	1996-01-17	日立マクセル株式会社	テ−プカ−トリッジ
JPH0699443B2 (ja) *	1989-09-29	1994-12-07	ファイザー製薬株式会社	セファロスポリン化合物

1987
- 1987-11-06 AT AT87309852T patent/ATE113050T1/de not_active IP Right Cessation
- 1987-11-06 DE DE3750673T patent/DE3750673T2/de not_active Expired - Fee Related
- 1987-11-20 JP JP62292235A patent/JPS63301887A/ja active Pending
- 1987-11-23 US US07/124,213 patent/US5114933A/en not_active Expired - Fee Related
1991
- 1991-09-05 US US07/755,618 patent/US5348951A/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
DE3750673D1 (de)	1994-11-24
US5114933A (en)	1992-05-19
DE3750673T2 (de)	1995-03-16
JPS63301887A (ja)	1988-12-08
US5348951A (en)	1994-09-20

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Legal Events

Date	Code	Title	Description
1995-05-15	UEP	Publication of translation of european patent specification
1996-08-15	REN	Ceased due to non-payment of the annual fee