DE68919085D1 - Verfahren zur herstellung eines polypeptids welches als menschlicher neutrophiler chemotaktischer faktor aktiv ist. - Google Patents

Verfahren zur herstellung eines polypeptids welches als menschlicher neutrophiler chemotaktischer faktor aktiv ist.

Info

Publication number
DE68919085D1
DE68919085D1 DE68919085T DE68919085T DE68919085D1 DE 68919085 D1 DE68919085 D1 DE 68919085D1 DE 68919085 T DE68919085 T DE 68919085T DE 68919085 T DE68919085 T DE 68919085T DE 68919085 D1 DE68919085 D1 DE 68919085D1
Authority
DE
Germany
Prior art keywords
chemotactic factor
polypeptide
active
producing
human neutrophilic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE68919085T
Other languages
English (en)
Other versions
DE68919085T2 (de
Inventor
Masaaki Yamada
Ryuji Furuta
Junichi Yamagishi
Kouji Matsushima
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sumitomo Pharma Co Ltd
United States Department of Health and Human Services
Original Assignee
Dainippon Pharmaceutical Co Ltd
United States Department of Health and Human Services
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dainippon Pharmaceutical Co Ltd, United States Department of Health and Human Services filed Critical Dainippon Pharmaceutical Co Ltd
Application granted granted Critical
Publication of DE68919085D1 publication Critical patent/DE68919085D1/de
Publication of DE68919085T2 publication Critical patent/DE68919085T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/54—Interleukins [IL]
    • C07K14/5421—IL-8
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • Toxicology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DE68919085T 1988-08-29 1989-08-29 Verfahren zur herstellung eines polypeptids welches als menschlicher neutrophiler chemotaktischer faktor aktiv ist. Expired - Lifetime DE68919085T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US23774188A 1988-08-29 1988-08-29
PCT/US1989/003728 WO1990002178A1 (en) 1988-08-29 1989-08-29 A method of preparing an active human neutrophil chemotactic factor polypeptide

Publications (2)

Publication Number Publication Date
DE68919085D1 true DE68919085D1 (de) 1994-12-01
DE68919085T2 DE68919085T2 (de) 1995-04-06

Family

ID=22894964

Family Applications (1)

Application Number Title Priority Date Filing Date
DE68919085T Expired - Lifetime DE68919085T2 (de) 1988-08-29 1989-08-29 Verfahren zur herstellung eines polypeptids welches als menschlicher neutrophiler chemotaktischer faktor aktiv ist.

Country Status (7)

Country Link
US (1) US5401643A (de)
EP (1) EP0431042B1 (de)
JP (1) JP3053631B2 (de)
KR (1) KR100197110B1 (de)
AT (1) ATE113312T1 (de)
DE (1) DE68919085T2 (de)
WO (1) WO1990002178A1 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5652338A (en) 1988-03-16 1997-07-29 The United States Of America As Represented By The Department Of Health And Human Services Neutrophil chemotactic factor
NZ541050A (en) 2002-12-16 2010-06-25 Genmab As Human monoclonal antibodies against interleukin 8 (IL-8)
AU2006294868B2 (en) * 2005-09-26 2011-03-03 Coupons, Inc. System and method for augmenting content in electronic documents with links to contextually relevant information
WO2019140150A1 (en) 2018-01-12 2019-07-18 Bristol-Myers Squibb Company Combination therapy with anti-il-8 antibodies and anti-pd-1 antibodies for treating cancer

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4511503A (en) * 1982-12-22 1985-04-16 Genentech, Inc. Purification and activity assurance of precipitated heterologous proteins
US4511502A (en) * 1982-12-22 1985-04-16 Genentech, Inc. Purification and activity assurance of precipitated heterologous proteins
US4897348A (en) * 1983-08-25 1990-01-30 Sri International Recombinant materials and methods for producing human connective tissue-activating peptide-III and analogs thereof
DE3890998B4 (de) * 1987-11-19 2008-01-03 Novartis Ag Neutrophilenaktivierungsfaktor, Verfahren zu seiner Herstellung und ihn enthaltende pharmazeutische Zusammensetzung
US5026639A (en) * 1988-01-14 1991-06-25 Nippon Mining Company, Limited Method to improve mRNA translation and use thereof for production of platelet factor-4

Also Published As

Publication number Publication date
JP3053631B2 (ja) 2000-06-19
DE68919085T2 (de) 1995-04-06
KR100197110B1 (ko) 1999-06-15
EP0431042A4 (en) 1992-03-11
ATE113312T1 (de) 1994-11-15
EP0431042A1 (de) 1991-06-12
US5401643A (en) 1995-03-28
WO1990002178A1 (en) 1990-03-08
EP0431042B1 (de) 1994-10-26
KR900702031A (ko) 1990-12-05
JPH04500156A (ja) 1992-01-16

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