ATE113600T1 - Benzodiazepinverbindungen und ihre verwendung als arzneimittel. - Google Patents

Benzodiazepinverbindungen und ihre verwendung als arzneimittel.

Info

Publication number: ATE113600T1
Authority: AT; Austria
Prior art keywords: benzodiazepin; pharmaceuticals; compounds; benzodiazepin compounds
Prior art date: 1988-08-11

Application number

AT89308099T

Other languages

English (en)

Inventor

Jiban Kumar Chakrabarti

Terrence Michael Hotten

Original Assignee

Lilly Industries Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1988-08-11

Filing date

1989-08-09

Publication date

1994-11-15

1989-08-09 Application filed by Lilly Industries Ltd filed Critical Lilly Industries Ltd

1994-11-15 Application granted granted Critical

1994-11-15 Publication of ATE113600T1 publication Critical patent/ATE113600T1/de

Links

SVUOLADPCWQTTE-UHFFFAOYSA-N 1h-1,2-benzodiazepine Chemical class N1N=CC=CC2=CC=CC=C12 SVUOLADPCWQTTE-UHFFFAOYSA-N 0.000 title 1
239000003814 drug Substances 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Neurosurgery (AREA)
General Health & Medical Sciences (AREA)
Biomedical Technology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Neurology (AREA)
Public Health (AREA)
Psychiatry (AREA)
Anesthesiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Thiazole And Isothizaole Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

AT89308099T 1988-08-11 1989-08-09 Benzodiazepinverbindungen und ihre verwendung als arzneimittel. ATE113600T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GB888819059A GB8819059D0 (en)	1988-08-11	1988-08-11	Benzodiazepine compounds & their use as pharmaceuticals

Publications (1)

Publication Number	Publication Date
ATE113600T1 true ATE113600T1 (de)	1994-11-15

Family

ID=10641942

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT89308099T ATE113600T1 (de)	1988-08-11	1989-08-09	Benzodiazepinverbindungen und ihre verwendung als arzneimittel.

Country Status (22)

Country	Link
US (2)	US4977150A (de)
EP (1)	EP0354781B1 (de)
JP (1)	JP2779219B2 (de)
KR (1)	KR0138527B1 (de)
CN (1)	CN1025857C (de)
AR (1)	AR246972A1 (de)
AT (1)	ATE113600T1 (de)
AU (1)	AU625067B2 (de)
CA (1)	CA1318669C (de)
DE (1)	DE68919154T2 (de)
DK (1)	DK393489A (de)
ES (1)	ES2062012T3 (de)
GB (1)	GB8819059D0 (de)
HU (1)	HU202239B (de)
IE (1)	IE64598B1 (de)
IL (1)	IL91246A (de)
MX (1)	MX17107A (de)
NZ (1)	NZ230251A (de)
PH (1)	PH27010A (de)
PT (1)	PT91401B (de)
RU (1)	RU2002752C1 (de)
ZA (1)	ZA896039B (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
BE1004596A4 (fr) *	1990-09-26	1992-12-22	Therabel Res S A N V	Derives de methylpiperazinoazepine, leur preparation et leur utilisation.
US5627178A (en)	1991-04-23	1997-05-06	Lilly Industries Limited	2-methyl-thieno-benzodiazepine
US5393752A (en) *	1992-05-26	1995-02-28	Therabel Research S.A./N.V.	Methylpiperazinoazepine compounds, preparation and use thereof
US6034078A (en) *	1992-05-29	2000-03-07	Eli Lilly And Company Limited	Thienobenzodiazepine compounds
US6617321B2 (en) *	1997-09-30	2003-09-09	Eli Lilly And Company	2-methyl-thieno-benzodiazepine formulation
ATE380818T1 (de)	2002-03-28	2007-12-15	Lilly Co Eli	Piperazine-substituierte aryl-benzodiazepinen und ihre verwendung als dopaminrezeptor-antagonisten zur behandlung von psychose
ES2285227T3 (es) *	2002-08-05	2007-11-16	Eli Lilly And Company	Arilbenzodiazepinas sustituidas con piperazina.
JP2007505106A (ja) *	2003-09-09	2007-03-08	イーライリリーアンドカンパニー	アゼピン、オキサゼピン、およびチアゼピンの置換ピペラジン
PL1838716T3 (pl) *	2005-01-05	2011-09-30	Lilly Co Eli	Dihydrat embonianu olanzapiny

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CH468400A (de) *	1965-12-23	1969-02-15	Sandoz Ag	Verfahren zur Herstellung neuer Thieno(2,3-b)(1,5)benzothiazepin-4-on-Verbindungen
US3539573A (en) *	1967-03-22	1970-11-10	Jean Schmutz	11-basic substituted dibenzodiazepines and dibenzothiazepines
US3758479A (en) *	1967-03-22	1973-09-11	Sandoz Ag	Nitro and sulphamoyl substituted dibenzodiazepines
GB1292410A (en) *	1970-05-13	1972-10-11	Yoshitomi Pharmaceutical	Thienobenzothiazepine derivatives
CH554362A (de) *	1970-07-30	1974-09-30	Spofa Vereinigte Pharma Werke	Verfahren zur herstellung von neuen estern tricyklischer piperazinoalkanole.
US3897446A (en) *	1973-09-04	1975-07-29	Upjohn Co	6-Phenylthiazolo{8 3,2-a{9 {8 1,4{9 benzodiazepin-1-(2H)-ones, and processes
SU629879A3 (ru) *	1974-11-26	1978-10-25	Лилли Индастриз Лимитед, (Фирма)	Способ получени тиено(1,5) бензодиазепинов или их солей
US4115568A (en) *	1974-11-26	1978-09-19	Lilly Industries Limited	Thieno[3,2-b]-[1,5]benzodiazepines
US3951981A (en) *	1975-02-24	1976-04-20	American Cyanamid Company	Substituted benzodiazepines and method of use
US4404137A (en) *	1979-10-16	1983-09-13	Lilly Industries Limited	Pyrazolo [3,4-b][1,5]benzodiazepine compounds
US4431589A (en) *	1980-12-11	1984-02-14	Lilly House	Benzodiazepine compounds and their use as pharmaceuticals

1988
- 1988-08-11 GB GB888819059A patent/GB8819059D0/en active Pending
1989
- 1989-08-04 US US07/390,029 patent/US4977150A/en not_active Expired - Lifetime
- 1989-08-07 PH PH39061A patent/PH27010A/en unknown
- 1989-08-07 AU AU39399/89A patent/AU625067B2/en not_active Ceased
- 1989-08-08 MX MX1710789A patent/MX17107A/es unknown
- 1989-08-08 IL IL9124689A patent/IL91246A/en not_active IP Right Cessation
- 1989-08-08 PT PT91401A patent/PT91401B/pt active IP Right Grant
- 1989-08-08 CA CA000607760A patent/CA1318669C/en not_active Expired - Fee Related
- 1989-08-08 ZA ZA896039A patent/ZA896039B/xx unknown
- 1989-08-08 NZ NZ230251A patent/NZ230251A/en unknown
- 1989-08-09 ES ES89308099T patent/ES2062012T3/es not_active Expired - Lifetime
- 1989-08-09 EP EP89308099A patent/EP0354781B1/de not_active Expired - Lifetime
- 1989-08-09 AT AT89308099T patent/ATE113600T1/de not_active IP Right Cessation
- 1989-08-09 DE DE68919154T patent/DE68919154T2/de not_active Expired - Fee Related
- 1989-08-10 IE IE257689A patent/IE64598B1/en not_active IP Right Cessation
- 1989-08-10 RU SU894614830A patent/RU2002752C1/ru active
- 1989-08-10 HU HU894101A patent/HU202239B/hu not_active IP Right Cessation
- 1989-08-10 KR KR1019890011365A patent/KR0138527B1/ko not_active Expired - Fee Related
- 1989-08-10 JP JP1207770A patent/JP2779219B2/ja not_active Expired - Lifetime
- 1989-08-10 AR AR89314625A patent/AR246972A1/es active
- 1989-08-10 DK DK393489A patent/DK393489A/da not_active Application Discontinuation
- 1989-08-10 CN CN89105557A patent/CN1025857C/zh not_active Expired - Fee Related
1990
- 1990-08-02 US US07/562,055 patent/US5051516A/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
IL91246A (en)	1994-01-25
HU202239B (en)	1991-02-28
ES2062012T3 (es)	1994-12-16
IE64598B1 (en)	1995-08-23
PT91401A (pt)	1990-03-08
JP2779219B2 (ja)	1998-07-23
US5051516A (en)	1991-09-24
EP0354781A3 (de)	1991-04-03
PH27010A (en)	1993-02-01
JPH02104591A (ja)	1990-04-17
EP0354781B1 (de)	1994-11-02
MX17107A (es)	1993-08-01
DK393489A (da)	1990-02-12
DK393489D0 (da)	1989-08-10
GB8819059D0 (en)	1988-09-14
DE68919154D1 (de)	1994-12-08
US4977150A (en)	1990-12-11
HUT53109A (en)	1990-09-28
EP0354781A2 (de)	1990-02-14
AU3939989A (en)	1990-02-15
IL91246A0 (en)	1990-03-19
KR0138527B1 (ko)	1998-05-15
AU625067B2 (en)	1992-07-02
ZA896039B (en)	1991-04-24
DE68919154T2 (de)	1995-03-09
CN1025857C (zh)	1994-09-07
CN1040798A (zh)	1990-03-28
IE892576L (en)	1990-02-11
KR900003179A (ko)	1990-03-23
RU2002752C1 (ru)	1993-11-15
PT91401B (pt)	1995-05-04
CA1318669C (en)	1993-06-01
AR246972A1 (es)	1994-10-31
NZ230251A (en)	1992-05-26

Legal Events

Date	Code	Title	Description
1995-04-15	UEP	Publication of translation of european patent specification
2004-05-15	REN	Ceased due to non-payment of the annual fee

Publication	Publication Date	Title
DE69404382D1 (de)	1997-09-04	Urea-Derivate und ihre Verwendung als ACAT-hemmenden Verbindungen
DE69430279D1 (de)	2002-05-08	Pyrimidinverbindungen und ihre Verwendung als Pharmazeutika
DE122008000020I1 (de)	2008-08-07	Disubstituierte bicyclische heterocyclen, ihre herstellung und ihre verwendung als arzneimittel
EP0676461A3 (de)	1997-07-23	Spiroverbindungen und ihre Verwendung als Elektrolumineszenzmaterialien.
DE3785312D1 (de)	1993-05-13	Substituierte tetrahydropyridinoxime und ihre verwendung als cholinergische heilmittel.
DE69332898D1 (de)	2003-05-22	4-Carboxamidopiperidinderivate und ihre Verwendung als Neurokinin Antagonisten
DE3770085D1 (de)	1991-06-20	Cyclodextrinclathrate von carbacyclinderivaten und ihre verwendung als arzneimittel.
DE59812907D1 (de)	2005-08-11	Substituierte Isochinolin-3-Carbonsäureamide, ihre Herstellung und ihre Verwendung als Arzneimittel
DE69618959D1 (de)	2002-03-14	Pyrimidone und ihre verwendug als fungizide
ATE310739T1 (de)	2005-12-15	Pyrazol-4-yl-benzoylderivate und ihre verwendung als herbizide
DE69009822D1 (de)	1994-07-21	Zusammensetzung und ihre Verwendung.
ATE129497T1 (de)	1995-11-15	Bicyclische pyranderivate und ihre verwendung als 5-lipoxygenasehemmer.
ATE243708T1 (de)	2003-07-15	Substituierte imidazolidinderivate, ihre herstellung, ihre verwendung und sie enthaltende pharmazeutische präparate
DE68926351D1 (de)	1996-05-30	Bestimmte dreikernige novolakoligomerderivate als photoaktive verbindungen und ihre verwendung in strahlungsempfindlichen mischungen
DE59208576D1 (de)	1997-07-10	3-Isoxazolylphenylverbindungen, ihre Herstellung und ihre Verwendung
DE69333264D1 (de)	2003-12-04	3-Phenyl-5-pyridyl-Triazole und ihre Verwendung als Insektizide
DE69314347D1 (de)	1997-11-06	Aldonamide und ihre verwendung als grenzflächenaktive substanzen
EP0707577A4 (de)	1996-11-06	Heme-bindende verbindungen und ihre verwendung
DE69319618D1 (de)	1998-08-13	4-benzoylisoxazole-derivate und ihre verwendung als herbizide
ATE113600T1 (de)	1994-11-15	Benzodiazepinverbindungen und ihre verwendung als arzneimittel.
DE3761138D1 (de)	1990-01-18	Nitratderivate und ihre verwendung als gefaesserweiterer.
DE59603787D1 (de)	2000-01-05	1-fluor-6,7-dihydro-5h-isochinolin-8-on-derivate und ihre verwendung in flüssigkristallinen mischungen
ATE9093T1 (de)	1984-09-15	Benzodiazepinderivate und ihre verwendung als arzneimittel.
ATE257154T1 (de)	2004-01-15	Triazoline und isoxazoline bis-oxime -derivate und ihre verwendung als pestizide
DE59407240D1 (de)	1998-12-10	Substituierte azadioxacycloalkene und ihre verwendung als fungizide