ATE119941T1 - Subtilisin-analoge. - Google Patents

Subtilisin-analoge.

Info

Publication number
ATE119941T1
ATE119941T1 AT88904041T AT88904041T ATE119941T1 AT E119941 T1 ATE119941 T1 AT E119941T1 AT 88904041 T AT88904041 T AT 88904041T AT 88904041 T AT88904041 T AT 88904041T AT E119941 T1 ATE119941 T1 AT E119941T1
Authority
AT
Austria
Prior art keywords
subtilisin
asn
calcium binding
gly
analogs
Prior art date
Application number
AT88904041T
Other languages
English (en)
Inventor
Mark M Zurowski
Yitzhak Stabinsky
Michael Levitt
Original Assignee
Amgen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=21891131&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE119941(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Amgen Inc filed Critical Amgen Inc
Application granted granted Critical
Publication of ATE119941T1 publication Critical patent/ATE119941T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/52—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea
    • C12N9/54—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea bacteria being Bacillus
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • C12N15/75—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Bacillus
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Plant Pathology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Cell Biology (AREA)
  • Detergent Compositions (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Cosmetics (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
AT88904041T 1987-04-10 1988-03-28 Subtilisin-analoge. ATE119941T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/036,872 US4914031A (en) 1987-04-10 1987-04-10 Subtilisin analogs

Publications (1)

Publication Number Publication Date
ATE119941T1 true ATE119941T1 (de) 1995-04-15

Family

ID=21891131

Family Applications (1)

Application Number Title Priority Date Filing Date
AT88904041T ATE119941T1 (de) 1987-04-10 1988-03-28 Subtilisin-analoge.

Country Status (14)

Country Link
US (1) US4914031A (de)
EP (1) EP0309565B2 (de)
JP (1) JP2590247B2 (de)
KR (1) KR960006120B1 (de)
AT (1) ATE119941T1 (de)
AU (1) AU612653B2 (de)
CA (1) CA1316473C (de)
DE (1) DE3853328T3 (de)
DK (1) DK175576B1 (de)
FI (1) FI105695B (de)
IL (1) IL85953A (de)
LV (1) LV11043B (de)
NO (1) NO179679C (de)
WO (1) WO1988008033A1 (de)

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DK686788A (da) 1988-12-09
FI885719A0 (fi) 1988-12-09
JP2590247B2 (ja) 1997-03-12
HK1007168A1 (en) 1999-04-01
JPH01502957A (ja) 1989-10-12
EP0309565A1 (de) 1989-04-05
DE3853328D1 (de) 1995-04-20
FI885719L (fi) 1988-12-09
LV11043A (lv) 1996-02-20
IL85953A (en) 1993-01-31
NO885484L (no) 1989-02-09
KR960006120B1 (ko) 1996-05-09
EP0309565B1 (de) 1995-03-15
NO179679B (no) 1996-08-19
IL85953A0 (en) 1988-09-30
EP0309565A4 (de) 1990-02-05
DK175576B1 (da) 2004-12-13
NO885484D0 (no) 1988-12-09
WO1988008033A1 (en) 1988-10-20
LV11043B (en) 1996-06-20
KR890700668A (ko) 1989-04-26
DE3853328T3 (de) 2002-06-06
DK686788D0 (da) 1988-12-09
CA1316473C (en) 1993-04-20
NO179679C (no) 1996-11-27
AU1701688A (en) 1988-11-04
DE3853328T2 (de) 1995-07-27
EP0309565B2 (de) 2001-08-22
US4914031A (en) 1990-04-03
AU612653B2 (en) 1991-07-18
FI105695B (fi) 2000-09-29

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