ATE123030T1 - Piperidin-derivate, ihre herstellung und ihre verwendung. - Google Patents

Piperidin-derivate, ihre herstellung und ihre verwendung.

Info

Publication number
ATE123030T1
ATE123030T1 AT90102913T AT90102913T ATE123030T1 AT E123030 T1 ATE123030 T1 AT E123030T1 AT 90102913 T AT90102913 T AT 90102913T AT 90102913 T AT90102913 T AT 90102913T AT E123030 T1 ATE123030 T1 AT E123030T1
Authority
AT
Austria
Prior art keywords
preparation
piperidine derivatives
piperidine
derivatives
Prior art date
Application number
AT90102913T
Other languages
English (en)
Inventor
Per Sauerberg
Preben H Olesen
Original Assignee
Novo Nordisk As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DK82589A external-priority patent/DK82589A/da
Priority claimed from DK231589A external-priority patent/DK231589D0/da
Application filed by Novo Nordisk As filed Critical Novo Nordisk As
Application granted granted Critical
Publication of ATE123030T1 publication Critical patent/ATE123030T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/06Antiglaucoma agents or miotics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
AT90102913T 1989-02-22 1990-02-14 Piperidin-derivate, ihre herstellung und ihre verwendung. ATE123030T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DK82589A DK82589A (da) 1989-02-22 1989-02-22 Piperidinforbindelser, deres fremstilling og anvendelse
DK231589A DK231589D0 (da) 1989-05-12 1989-05-12 Piperidinforbindelser og deres fremstilling og anvendelse

Publications (1)

Publication Number Publication Date
ATE123030T1 true ATE123030T1 (de) 1995-06-15

Family

ID=26064725

Family Applications (1)

Application Number Title Priority Date Filing Date
AT90102913T ATE123030T1 (de) 1989-02-22 1990-02-14 Piperidin-derivate, ihre herstellung und ihre verwendung.

Country Status (22)

Country Link
US (5) US5043345A (de)
EP (2) EP0384288B1 (de)
JP (2) JPH02255680A (de)
KR (1) KR0163763B1 (de)
CN (1) CN1028105C (de)
AR (1) AR247565A1 (de)
AT (1) ATE123030T1 (de)
AU (2) AU4999690A (de)
CA (2) CA2010579A1 (de)
DE (1) DE69019550T2 (de)
DK (1) DK0384288T3 (de)
ES (1) ES2072323T3 (de)
FI (2) FI900887A7 (de)
GR (1) GR3017062T3 (de)
HU (2) HU221623B1 (de)
IE (1) IE69672B1 (de)
IL (2) IL93352A (de)
NO (2) NO900831L (de)
NZ (1) NZ232615A (de)
PH (1) PH26465A (de)
PT (2) PT93242A (de)
RU (1) RU2042676C1 (de)

Families Citing this family (92)

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EP0372125A1 (de) * 1988-11-08 1990-06-13 Akzo N.V. Oxazol und Thiazol-Derivate
US5328925A (en) * 1989-02-22 1994-07-12 Novo Nordisk A/S Piperidine compounds and their use
US5043345A (en) * 1989-02-22 1991-08-27 Novo Nordisk A/S Piperidine compounds and their preparation and use
US5260311A (en) * 1989-02-22 1993-11-09 Novo Nordisk A/S Piperidine compounds and their use
US5264444A (en) * 1989-02-22 1993-11-23 Novo Nordisk A/S Piperidine compounds and use
EP0459568A3 (en) * 1990-05-31 1992-09-30 Merck Sharp & Dohme Ltd. Substituted oxadiazoles and thiadiazoles for use in the treatment of glaucoma and novel compounds having such use
DK198590D0 (da) * 1990-08-21 1990-08-21 Novo Nordisk As Heterocykliske forbindelser, deres fremstilling og anvendelse
USRE35822E (en) * 1990-08-21 1998-06-09 Novo Nordisk A/S Heterocyclic compounds
US5527813A (en) * 1990-08-21 1996-06-18 Novo Nordisk A/S Heterocyclic compounds and their preparation and use
DK198490D0 (da) * 1990-08-21 1990-08-21 Novo Nordisk As Heterocykliske forbindelser, deres fremstilling og anvendelse
US5418240A (en) * 1990-08-21 1995-05-23 Novo Nordisk A/S Heterocyclic compounds and their preparation and use
US5376668A (en) * 1990-08-21 1994-12-27 Novo Nordisk A/S Heterocyclic compounds
DK198390D0 (da) * 1990-08-21 1990-08-21 Novo Nordisk As Heterocykliske forbindelser, deres fremstilling og anvendelse
AU656547B2 (en) * 1990-11-29 1995-02-09 Allergan, Inc. Use of pyridine derivatives in the treatment of ocular hypertension
EP0492903A1 (de) * 1990-12-21 1992-07-01 MERCK SHARP & DOHME LTD. Substituierte Pyrazine, Pyrimidine und Pyridazine zur Anwendung in der Behandlung von Glaukoma
IE922270A1 (en) * 1991-07-26 1993-01-27 Akzo Nv Pyrazole derivatives
US5641791A (en) * 1991-08-13 1997-06-24 Novo Nordisk A.S Heterocyclic compounds and their preparation and use
US5175166A (en) * 1991-08-27 1992-12-29 The University Of Toledo Muscarinic agonists
WO1993014089A1 (en) * 1992-01-13 1993-07-22 Novo Nordisk A/S Heterocyclic compounds and their preparation and use
US5244906A (en) * 1992-01-23 1993-09-14 Dowelanco Insect control with substituted oxadiazole and thiadiazole compounds
ES2133416T3 (es) * 1992-10-23 1999-09-16 Merck Sharp & Dohme Ligandos de subtipos de receptores de dopamina.
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IL112024A (en) * 1993-12-21 1999-07-14 Novo Nordisk As Pharmaceutical compositions comprising tetrahydropyridine derivatives substituted with oxadiazole or thiadiazole for treating gastrointestinal motility disorders
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US5612351A (en) * 1994-11-08 1997-03-18 Novo Nordisk A/S Method of treating urinary bladder dysfunctions
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US6117890A (en) * 1996-08-01 2000-09-12 Eli Lilly And Company Method for treating bipolar disorder
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ATE213413T1 (de) * 1996-08-01 2002-03-15 Lilly Co Eli Verwendung von 3-(4-hexyloxy-1,2,5-thiadiazol-3- yl)-1,2,5,6-tetrahydro-1-methylpyridin (xanomelin) zur behandlung von bipolaren störungen
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CN1821243B (zh) * 2005-08-30 2010-12-08 北京大学 取代的吡啶类m1受体激动剂、其制备方法及其用途
EP2377530A3 (de) 2005-10-21 2012-06-20 Braincells, Inc. Modulation von Neurogenese durch PDE-Hemmung
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UA128017C2 (uk) 2018-09-28 2024-03-13 Каруна Тереп'Ютікс, Інк. Композиція і спосіб лікування розладу, що послаблюється активацією мускаринових рецепторів (варіанти)
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NZ219646A (en) * 1986-03-27 1990-10-26 Merck Sharp & Dohme Oxadiazole derivatives of azacyclics for treating cns disorders
IL83275A (en) * 1986-09-08 1994-02-27 Novo Nordisk As Substituted 1, 2, 4- oxadiazolyl piperidine compounds, their preparation and pharmaceutical compositions containing them
US5017618A (en) * 1987-03-16 1991-05-21 University Of Florida Labile derivatives of ketone analogs of 3-substituted-1-alkylamino-2-propanols and their use as beta-adrenergic blockers
GB8714789D0 (en) * 1987-06-24 1987-07-29 Lundbeck & Co As H Heterocyclic compounds
NZ225999A (en) * 1987-09-10 1992-04-28 Merck Sharp & Dohme Azacyclic- or azabicyclic-substituted thiadiazole derivatives and pharmaceutical compositions
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DK162892C (da) * 1988-07-04 1992-05-11 Novo Nordisk As 1,2,5,6-tetrahydropyridinforbindelser, deres fremstilling og farmaceutiske praeparater indeholdende disse
US5328925A (en) * 1989-02-22 1994-07-12 Novo Nordisk A/S Piperidine compounds and their use
US5260311A (en) * 1989-02-22 1993-11-09 Novo Nordisk A/S Piperidine compounds and their use
US5043345A (en) * 1989-02-22 1991-08-27 Novo Nordisk A/S Piperidine compounds and their preparation and use
US5264444A (en) * 1989-02-22 1993-11-23 Novo Nordisk A/S Piperidine compounds and use
DK198490D0 (da) * 1990-08-21 1990-08-21 Novo Nordisk As Heterocykliske forbindelser, deres fremstilling og anvendelse
DK198390D0 (da) * 1990-08-21 1990-08-21 Novo Nordisk As Heterocykliske forbindelser, deres fremstilling og anvendelse
US5175166A (en) * 1991-08-27 1992-12-29 The University Of Toledo Muscarinic agonists

Also Published As

Publication number Publication date
GR3017062T3 (en) 1995-11-30
US5712297A (en) 1998-01-27
PT93242A (pt) 1990-08-31
AU4999690A (en) 1990-08-30
HU900884D0 (en) 1990-05-28
IE900504L (en) 1990-08-22
CN1045104A (zh) 1990-09-05
PT93241B (pt) 1996-01-31
JPH02255680A (ja) 1990-10-16
US5284859A (en) 1994-02-08
DE69019550D1 (de) 1995-06-29
NO900830L (no) 1990-08-23
NO900831D0 (no) 1990-02-21
NO179639C (no) 1996-11-20
KR0163763B1 (ko) 1998-12-01
NO179639B (no) 1996-08-12
AR247565A1 (es) 1995-01-31
EP0384288B1 (de) 1995-05-24
FI900886A0 (fi) 1990-02-22
FI900887A7 (fi) 1990-08-23
NZ232615A (en) 1992-06-25
JP2921578B2 (ja) 1999-07-19
CA2010578A1 (en) 1990-08-22
FI900887A0 (fi) 1990-02-22
EP0384288A3 (de) 1991-04-10
ES2072323T3 (es) 1995-07-16
US5043345A (en) 1991-08-27
US5041455A (en) 1991-08-20
HU211705A9 (en) 1995-12-28
RU2042676C1 (ru) 1995-08-27
JPH02255679A (ja) 1990-10-16
IE69672B1 (en) 1996-10-02
HUT58326A (en) 1992-02-28
PH26465A (en) 1992-07-27
IL93352A (en) 1994-08-26
IL93423A0 (en) 1990-11-29
FI95704B (fi) 1995-11-30
EP0384285A3 (de) 1991-04-24
EP0384285A2 (de) 1990-08-29
DK0384288T3 (da) 1995-10-02
PT93241A (pt) 1990-08-31
CA2010579A1 (en) 1990-08-22
AU4999790A (en) 1990-08-30
FI95704C (fi) 1996-03-11
AU629302B2 (en) 1992-10-01
NO900831L (no) 1990-08-23
IL93352A0 (en) 1990-11-29
CN1028105C (zh) 1995-04-05
CA2010578C (en) 2000-05-23
NO900830D0 (no) 1990-02-21
US5559138A (en) 1996-09-24
HU221623B1 (hu) 2002-12-28
KR910015569A (ko) 1991-09-30
DE69019550T2 (de) 1995-10-05
EP0384288A2 (de) 1990-08-29

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