ATE129890T1 - Komposition für die behandlung von augenschmerzen. - Google Patents

Komposition für die behandlung von augenschmerzen.

Info

Publication number: ATE129890T1
Authority: AT; Austria
Prior art keywords: treatment; composition; eye pain; pain; calcium channel
Prior art date: 1990-09-07

Application number

AT91915701T

Other languages

English (en)

Inventor

Carlos Univ Belmonte-Martinez

Roberto Univ Gallego-Fernandez

Miguel Angel Univ Pozo-Garcia

Juana Univ De Gallar-Martinez

Original Assignee

Univ Alicante

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1990-09-07

Filing date

1991-08-30

Publication date

1995-11-15

1991-08-30 Application filed by Univ Alicante filed Critical Univ Alicante

1995-11-15 Application granted granted Critical

1995-11-15 Publication of ATE129890T1 publication Critical patent/ATE129890T1/de

Links

206010015958 Eye pain Diseases 0.000 title abstract 2
239000000480 calcium channel blocker Substances 0.000 abstract 2
SGTNSNPWRIOYBX-UHFFFAOYSA-N 2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile Chemical compound C1=C(OC)C(OC)=CC=C1CCN(C)CCCC(C#N)(C(C)C)C1=CC=C(OC)C(OC)=C1 SGTNSNPWRIOYBX-UHFFFAOYSA-N 0.000 abstract 1
ZBBHBTPTTSWHBA-UHFFFAOYSA-N Nicardipine Chemical compound COC(=O)C1=C(C)NC(C)=C(C(=O)OCCN(C)CC=2C=CC=CC=2)C1C1=CC=CC([N+]([O-])=O)=C1 ZBBHBTPTTSWHBA-UHFFFAOYSA-N 0.000 abstract 1
208000002193 Pain Diseases 0.000 abstract 1
HSUGRBWQSSZJOP-RTWAWAEBSA-N diltiazem Chemical compound C1=CC(OC)=CC=C1[C@H]1[C@@H](OC(C)=O)C(=O)N(CCN(C)C)C2=CC=CC=C2S1 HSUGRBWQSSZJOP-RTWAWAEBSA-N 0.000 abstract 1
229960004166 diltiazem Drugs 0.000 abstract 1
239000003814 drug Substances 0.000 abstract 1
238000004519 manufacturing process Methods 0.000 abstract 1
229960001783 nicardipine Drugs 0.000 abstract 1
HYIMSNHJOBLJNT-UHFFFAOYSA-N nifedipine Chemical compound COC(=O)C1=C(C)NC(C)=C(C(=O)OC)C1C1=CC=CC=C1[N+]([O-])=O HYIMSNHJOBLJNT-UHFFFAOYSA-N 0.000 abstract 1
229960001597 nifedipine Drugs 0.000 abstract 1
229960001722 verapamil Drugs 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/275—Nitriles; Isonitriles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Engineering & Computer Science (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Organic Chemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
Pain & Pain Management (AREA)
Ophthalmology & Optometry (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Medicinal Preparation (AREA)

AT91915701T 1990-09-07 1991-08-30 Komposition für die behandlung von augenschmerzen. ATE129890T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
ES9002335		1990-09-07

Publications (1)

Publication Number	Publication Date
ATE129890T1 true ATE129890T1 (de)	1995-11-15

Family

ID=8268787

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT91915701T ATE129890T1 (de)	1990-09-07	1991-08-30	Komposition für die behandlung von augenschmerzen.

Country Status (8)

Country	Link
EP (1)	EP0502143B1 (de)
JP (1)	JPH05506035A (de)
AT (1)	ATE129890T1 (de)
CA (1)	CA2073003A1 (de)
DE (1)	DE69114470T2 (de)
IE (1)	IE913137A1 (de)
PT (1)	PT98895A (de)
WO (1)	WO1992004008A1 (de)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5854233A (en) *	1993-09-08	1998-12-29	Pharmacy And Therapeutic Advisory Consultancy Ltd.	Method of treating liver disease and like indications with vasodilating agents
US6174917B1 (en)	1993-09-08	2001-01-16	Pharmacy And Therapeutic Advisory Consultancy Ltd.	Method of treating liver disease and like indications with vasodilating agents
EP0717625B1 (de) *	1993-09-08	2002-06-12	Pharmacy and Therapeutic Advisory Consultancy Ltd.	Verfahren zur behandlung von lebererkrankungen und ähnlichen indikationen mit vasodilatierenden wirkstoffen
WO1995034299A1 (en) *	1994-06-10	1995-12-21	Telor Ophthalmic Pharmaceuticals, Inc.	Inhibition of intraoperative miosis/production of mydriasis by calcium channel blockers
WO1996019233A2 (en) *	1994-12-12	1996-06-27	Omeros Medical Systems, Inc.	Irrigation solution and method for inhibition of pain, inflammation and spasm
US6492332B1 (en)	1995-12-12	2002-12-10	Omeros Corporation	Irrigation solution and methods for inhibition of tumor cell adhesion, pain and inflammation
KR100517210B1 (ko) *	1994-12-12	2006-06-07	오메로스 코포레이션	통증,염증및경련억제용관주용액
JPH10510540A (ja)	1994-12-12	1998-10-13	オメロスメディカルシステムズ，インコーポレーテッド	灌注用溶液並びに疼痛、炎症及びけいれんの抑制法
US7091181B2 (en)	1994-12-12	2006-08-15	Omeros Corporation	Method of inhibition of pain and inflammation during surgery comprising administration of soluble TNF receptors
US6413961B1 (en)	1995-12-12	2002-07-02	Omeros Medical Systems, Inc.	Irrigation solution and method for inhibition of pain and inflammation
US6225327B1 (en)	1996-04-18	2001-05-01	Alcon Laboratories, Inc.	Compounds which inhibit human conjunctival mast cell degranulation for treating ocular allergic-type complications
US6294553B1 (en) *	2000-02-15	2001-09-25	Allergan Sales, Inc.	Method for treating ocular pain
CN101327325A (zh)	2002-07-30	2008-12-24	奥默罗斯公司	眼科冲洗液及方法
WO2004069275A1 (ja) *	2003-02-04	2004-08-19	Mitsubishi Pharma Corporation	眼科用剤
AU2013201465B2 (en)	2012-10-24	2016-03-03	Rayner Intraocular Lenses Limited	Stable preservative-free mydriatic and anti-inflammatory solutions for injection
CN104994839A (zh) *	2013-02-13	2015-10-21	诺华股份有限公司	局部眼用镇痛剂
TWI705812B (zh)	2014-12-01	2020-10-01	奥默羅斯公司	用於抑制術後眼睛炎性病況的抗炎和散瞳前房溶液

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4552695A (en) *	1983-04-21	1985-11-12	Shionogi & Co., Ltd.	Process for production of diltiazem hydrochloride
US4981871A (en) *	1987-05-15	1991-01-01	Abelson Mark B	Treatment of ocular hypertension with class I calcium channel blocking agents
CA2004616A1 (en) *	1988-12-05	1990-06-05	Craig E. Crosson	Therapeutic use of calcium entry blockers in retinal or optic nerve dysfunction

1991
- 1991-08-30 WO PCT/EP1991/001656 patent/WO1992004008A1/en not_active Ceased
- 1991-08-30 AT AT91915701T patent/ATE129890T1/de active
- 1991-08-30 EP EP91915701A patent/EP0502143B1/de not_active Expired - Lifetime
- 1991-08-30 CA CA002073003A patent/CA2073003A1/en not_active Abandoned
- 1991-08-30 JP JP91513914A patent/JPH05506035A/ja active Pending
- 1991-08-30 DE DE69114470T patent/DE69114470T2/de not_active Expired - Fee Related
- 1991-09-06 IE IE313791A patent/IE913137A1/en unknown
- 1991-09-06 PT PT98895A patent/PT98895A/pt not_active Application Discontinuation

Also Published As

Publication number	Publication date
DE69114470D1 (de)	1995-12-14
EP0502143A1 (de)	1992-09-09
DE69114470T2 (de)	1996-07-18
EP0502143B1 (de)	1995-11-08
CA2073003A1 (en)	1992-03-08
WO1992004008A1 (en)	1992-03-19
PT98895A (pt)	1992-07-31
IE913137A1 (en)	1992-03-11
JPH05506035A (ja)	1993-09-02

Publication	Publication Date	Title
DE69114470D1 (de)	1995-12-14	Komposition für die behandlung von augenschmerzen.
DE60101265D1 (de)	2003-12-24	Behandlung von augenschmerzen
FR05C0033I2 (fr)	2006-12-29	R-enantiomere de n-propargyl-1-amino-indane pour le traitement des maladies diverses et son mesylate, esylate et sulfate
DE60117043D1 (de)	2006-04-13	Behandlung von mukositis
DK0415613T3 (da)	1994-10-10	Anvendelse af sertralin til behandling af præmatur ejakulation
SE9702860D0 (sv)	1997-08-05	New use
ES2087160T3 (es)	1996-07-16	Composiciones y procedimiento para el tratamiento de trastornos dolorosos, inflamatorios o alergicos.
MX9305248A (es)	1995-01-31	Compuestos de diarilpiperazinoacetamida.
DK261490D0 (da)	1990-10-31	New pharmaceutical compound
DE3872701D1 (de)	1992-08-13	Prostaglandin-derivate zur behandlung von glaucoma oder augenueberdruck.
DE69227696D1 (de)	1999-01-07	Zusammensetzungen zur behandlung von hiv-infektionen
EE200100188A (et)	2002-08-15	Optiliselt aktiivne püridüül-4H-1,2,4-oksadiasiini derivaat ja selle kasutamine vaskulaarsete haiguste ravis
DE69927380D1 (de)	2005-10-27	Oxazolidinones zur behandlung von augeninfektionen
ATE142875T1 (de)	1996-10-15	Methode zur behandlung von haarausfall
DK161320C (da)	1991-12-09	Analogifremgangsmaade til fremstilling af 2,3-diaryl-5-halogen-thiophener
ATE117208T1 (de)	1995-02-15	Behandlung von intraokularem druck mit einer ophthalmischen synergistischen kombination.
ATE359808T1 (de)	2007-05-15	Verwendung von sarp-1 zur behandlung und/oder vorbeugung von scleroderma
ATE132750T1 (de)	1996-01-15	Behandlung von intraokularem druck mit einer synergischen kombination
DK1100824T3 (da)	2011-06-20	Forbindelser med væksthormonfrigivende egenskaber
DE69010523D1 (de)	1994-08-18	Kit oder Zusammensetzung zur Vorbeugung oder Behandlung von HIV-1 Infektionen.
ATE554787T1 (de)	2012-05-15	Behandlung von typ-1-diabetes vor und nach der expression von prädispositionsmarkern
ATE271867T1 (de)	2004-08-15	Behandlung der harninkontinenz und zusammenstellung dafür
DE3585312D1 (de)	1992-03-12	Anwendung von 1,6-dimethyl-4-oxo-1,6,7,8,9a-hexahydro-4h-pyrido(1,2-a)pyrimidin-3-carboxamid zur vorbeugung und behandlung von gastrointestinalschaeden.
ATE323497T1 (de)	2006-05-15	Idraparinux (sanorg 34006) zur behandlung und sekundärprophylaxe von thromboembolien bei patienten mit tiefer venenthrombose
DE60017786T8 (de)	2006-08-24	Zusammensetzung mit retinal und aldehyde mit pilzverhütender aktivität