ATE135682T1 - 2-(3-phenylpropyl)hydrazine, verfahren zu ihrer herstellung, zwischenprodukte dafür und ihre verwendung als medikamente - Google Patents

2-(3-phenylpropyl)hydrazine, verfahren zu ihrer herstellung, zwischenprodukte dafür und ihre verwendung als medikamente

Info

Publication number: ATE135682T1
Authority: AT; Austria
Prior art keywords: loweralkyl; hydrogen; formula; hydrazines; chem
Prior art date: 1991-12-05

Application number

AT92120719T

Other languages

English (en)

Inventor

Richard Charles Effland

Joseph Thomas Klein

Original Assignee

Hoechst Roussel Pharma

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1991-12-05

Filing date

1992-12-04

Publication date

1996-04-15

1992-12-04 Application filed by Hoechst Roussel Pharma filed Critical Hoechst Roussel Pharma

1996-04-15 Application granted granted Critical

1996-04-15 Publication of ATE135682T1 publication Critical patent/ATE135682T1/de

Links

229940079593 drug Drugs 0.000 title 1
239000003814 drug Substances 0.000 title 1
150000002429 hydrazines Chemical class 0.000 title 1
239000013067 intermediate product Substances 0.000 title 1
229910052739 hydrogen Inorganic materials 0.000 abstract 4
239000001257 hydrogen Substances 0.000 abstract 4
150000002431 hydrogen Chemical group 0.000 abstract 3
XGHYJNACLMGUNQ-UHFFFAOYSA-N (3-phenoxy-3-phenylpropyl)hydrazine Chemical class C=1C=CC=CC=1C(CCNN)OC1=CC=CC=C1 XGHYJNACLMGUNQ-UHFFFAOYSA-N 0.000 abstract 1
208000021384 Obsessive-Compulsive disease Diseases 0.000 abstract 1
239000002253 acid Substances 0.000 abstract 1
125000003118 aryl group Chemical group 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
229910052736 halogen Inorganic materials 0.000 abstract 1
150000002367 halogens Chemical class 0.000 abstract 1
125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
239000000543 intermediate Substances 0.000 abstract 1
-1 loweralkyl Chemical group 0.000 abstract 1
230000003287 optical effect Effects 0.000 abstract 1
208000022821 personality disease Diseases 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C243/00—Compounds containing chains of nitrogen atoms singly-bound to each other, e.g. hydrazines, triazanes
- C07C243/24—Hydrazines having nitrogen atoms of hydrazine groups acylated by carboxylic acids
- C07C243/26—Hydrazines having nitrogen atoms of hydrazine groups acylated by carboxylic acids with acylating carboxyl groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C243/28—Hydrazines having nitrogen atoms of hydrazine groups acylated by carboxylic acids with acylating carboxyl groups bound to hydrogen atoms or to acyclic carbon atoms to hydrogen atoms or to carbon atoms of a saturated carbon skeleton
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C243/00—Compounds containing chains of nitrogen atoms singly-bound to each other, e.g. hydrazines, triazanes
- C07C243/04—N-nitroso compounds
- C07C243/06—N-nitroso-amines
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C243/00—Compounds containing chains of nitrogen atoms singly-bound to each other, e.g. hydrazines, triazanes
- C07C243/10—Hydrazines
- C07C243/12—Hydrazines having nitrogen atoms of hydrazine groups bound to acyclic carbon atoms
- C07C243/16—Hydrazines having nitrogen atoms of hydrazine groups bound to acyclic carbon atoms of an unsaturated carbon skeleton
- C07C243/18—Hydrazines having nitrogen atoms of hydrazine groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C243/00—Compounds containing chains of nitrogen atoms singly-bound to each other, e.g. hydrazines, triazanes
- C07C243/24—Hydrazines having nitrogen atoms of hydrazine groups acylated by carboxylic acids
- C07C243/26—Hydrazines having nitrogen atoms of hydrazine groups acylated by carboxylic acids with acylating carboxyl groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C243/30—Hydrazines having nitrogen atoms of hydrazine groups acylated by carboxylic acids with acylating carboxyl groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of an unsaturated carbon skeleton
- C07C243/32—Hydrazines having nitrogen atoms of hydrazine groups acylated by carboxylic acids with acylating carboxyl groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of an unsaturated carbon skeleton the carbon skeleton containing rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C281/00—Derivatives of carbonic acid containing functional groups covered by groups C07C269/00 - C07C279/00 in which at least one nitrogen atom of these functional groups is further bound to another nitrogen atom not being part of a nitro or nitroso group
- C07C281/02—Compounds containing any of the groups, e.g. carbazates

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Psychiatry (AREA)
Anesthesiology (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

AT92120719T 1991-12-05 1992-12-04 2-(3-phenylpropyl)hydrazine, verfahren zu ihrer herstellung, zwischenprodukte dafür und ihre verwendung als medikamente ATE135682T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US07/802,599 US5229417A (en)	1991-12-05	1991-12-05	2-(3-phenylpropyl)hydrazines and method of treating personality disorders

Publications (1)

Publication Number	Publication Date
ATE135682T1 true ATE135682T1 (de)	1996-04-15

Family

ID=25184177

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT92120719T ATE135682T1 (de)	1991-12-05	1992-12-04	2-(3-phenylpropyl)hydrazine, verfahren zu ihrer herstellung, zwischenprodukte dafür und ihre verwendung als medikamente

Country Status (8)

Country	Link
US (1)	US5229417A (de)
EP (1)	EP0545425B1 (de)
JP (1)	JP2580452B2 (de)
AT (1)	ATE135682T1 (de)
DE (1)	DE69209242T2 (de)
DK (1)	DK0545425T3 (de)
ES (1)	ES2085540T3 (de)
GR (1)	GR3019469T3 (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AU4798400A (en) *	1999-05-10	2000-11-21	Eli Lilly And Company	Process for crystallizing (r)-fluoxetine hydrochloride

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AT218005B (de) *	1958-12-01	1961-11-10	Ciba Geigy	Verfahren zur Herstellung neuer Hydrazinverbindungen und deren Salze und Acylierungsprodukte
US3158618A (en) *	1962-05-14	1964-11-24	Dow Chemical Co	Nu-(acylamino)-ephedrines
US4584404A (en) *	1974-01-10	1986-04-22	Eli Lilly And Company	Substituted phenoxyphenylproply dimethylamines
US4626549A (en) *	1974-01-10	1986-12-02	Eli Lilly And Company	Treatment of obesity with aryloxyphenylpropylamines
US4018895A (en) *	1974-01-10	1977-04-19	Eli Lilly And Company	Aryloxyphenylpropylamines in treating depression

1991
- 1991-12-05 US US07/802,599 patent/US5229417A/en not_active Expired - Fee Related
1992
- 1992-12-04 AT AT92120719T patent/ATE135682T1/de not_active IP Right Cessation
- 1992-12-04 ES ES92120719T patent/ES2085540T3/es not_active Expired - Lifetime
- 1992-12-04 DE DE69209242T patent/DE69209242T2/de not_active Expired - Fee Related
- 1992-12-04 DK DK92120719.7T patent/DK0545425T3/da active
- 1992-12-04 EP EP92120719A patent/EP0545425B1/de not_active Expired - Lifetime
- 1992-12-04 JP JP4324544A patent/JP2580452B2/ja not_active Expired - Lifetime
1996
- 1996-03-29 GR GR960400848T patent/GR3019469T3/el unknown

Also Published As

Publication number	Publication date
DE69209242D1 (de)	1996-04-25
EP0545425B1 (de)	1996-03-20
GR3019469T3 (en)	1996-06-30
EP0545425A1 (de)	1993-06-09
DE69209242T2 (de)	1996-09-19
JP2580452B2 (ja)	1997-02-12
US5229417A (en)	1993-07-20
ES2085540T3 (es)	1996-06-01
DK0545425T3 (da)	1996-08-05
JPH05246970A (ja)	1993-09-24

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Legal Events

Date	Code	Title	Description
1996-09-15	UEP	Publication of translation of european patent specification
2005-09-15	REN	Ceased due to non-payment of the annual fee