ATE15606T1 - Durch osmose wirksame vorrichtung mit hydrogel als osmotisches mittel. - Google Patents

Durch osmose wirksame vorrichtung mit hydrogel als osmotisches mittel.

Info

Publication number: ATE15606T1
Authority: AT; Austria
Prior art keywords: hydrogel; osmosic; osmotic agent; agent; osmotic
Prior art date: 1980-11-25

Application number

AT81303354T

Other languages

English (en)

Inventor

Richard Cortese

Felix Theeuwes

Original Assignee

Alza Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1980-11-25

Filing date

1981-07-22

Publication date

1985-10-15

1981-07-22 Application filed by Alza Corp filed Critical Alza Corp

1985-10-15 Application granted granted Critical

1985-10-15 Publication of ATE15606T1 publication Critical patent/ATE15606T1/de

Links

239000000017 hydrogel Substances 0.000 title abstract 2
239000002357 osmotic agent Substances 0.000 title 1
239000013060 biological fluid Substances 0.000 abstract 1
239000012530 fluid Substances 0.000 abstract 1
230000003204 osmotic effect Effects 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
- A61K9/0004—Osmotic delivery systems; Sustained release driven by osmosis, thermal energy or gas
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S604/00—Surgery
- Y10S604/904—Tampons

Landscapes

Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Medicinal Preparation (AREA)
Materials For Medical Uses (AREA)
External Artificial Organs (AREA)
Physical Or Chemical Processes And Apparatus (AREA)
Prostheses (AREA)
Colloid Chemistry (AREA)
Infusion, Injection, And Reservoir Apparatuses (AREA)
Feeding, Discharge, Calcimining, Fusing, And Gas-Generation Devices (AREA)
Agricultural Chemicals And Associated Chemicals (AREA)
Separation Using Semi-Permeable Membranes (AREA)

AT81303354T 1980-11-25 1981-07-22 Durch osmose wirksame vorrichtung mit hydrogel als osmotisches mittel. ATE15606T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US06/210,176 US4327725A (en)	1980-11-25	1980-11-25	Osmotic device with hydrogel driving member
EP81303354A EP0052917B1 (de)	1980-11-25	1981-07-22	Durch Osmose wirksame Vorrichtung mit Hydrogel als osmotisches Mittel

Publications (1)

Publication Number	Publication Date
ATE15606T1 true ATE15606T1 (de)	1985-10-15

Family

ID=22781870

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT81303354T ATE15606T1 (de)	1980-11-25	1981-07-22	Durch osmose wirksame vorrichtung mit hydrogel als osmotisches mittel.

Country Status (6)

Country	Link
US (1)	US4327725A (de)
EP (1)	EP0052917B1 (de)
JP (1)	JPS6043045B2 (de)
AT (1)	ATE15606T1 (de)
DE (1)	DE3172338D1 (de)
MX (1)	MX174160B (de)

Families Citing this family (933)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4479795A (en) *	1979-06-29	1984-10-30	The Procter & Gamble Company	Antimicrobial polymer compositions
US4764380A (en) *	1982-03-22	1988-08-16	Alza Corporation	Drug delivery system comprising a volume increasing matrix containing a plurality of tiny pills
US5366738A (en) *	1982-07-29	1994-11-22	Merck & Co., Inc.	Controlled release drug dispersion delivery device
US4466705A (en) *	1982-09-30	1984-08-21	Michelson Paul E	Fluid lens
US4709996A (en) *	1982-09-30	1987-12-01	Michelson Paul E	Fluid lens
US4613330A (en) *	1982-11-26	1986-09-23	Michelson Paul E	Delivery system for desired agents
GB8305797D0 (en) *	1983-03-02	1983-04-07	Graham N B	Hydrogel-containing envelopes
US4765989A (en) *	1983-05-11	1988-08-23	Alza Corporation	Osmotic device for administering certain drugs
AT394944B (de) *	1983-05-11	1992-07-27	Alza Corp	Verfahren zur herstellung einer vorrichtung zur abgabe eines wirkstoffes, insbesondere eines heilmittels, an eine waesserige verwendungsumgebung
US5082668A (en) *	1983-05-11	1992-01-21	Alza Corporation	Controlled-release system with constant pushing source
US4783337A (en) *	1983-05-11	1988-11-08	Alza Corporation	Osmotic system comprising plurality of members for dispensing drug
NZ206600A (en) *	1983-05-11	1987-01-23	Alza Corp	Osmotic drug delivery device
USRE33994E (en) *	1983-08-16	1992-07-14	Burroughs Wellcome Co.	Pharmaceutical delivery system
AU591171B2 (en) *	1983-11-02	1989-11-30	Alza Corporation	Dispenser for delivering thermo-responsive composition
US4781714A (en) *	1983-11-02	1988-11-01	Alza Corporation	Dispenser for delivering thermo-responsive composition
US4627850A (en) *	1983-11-02	1986-12-09	Alza Corporation	Osmotic capsule
US4624945A (en) *	1984-03-19	1986-11-25	Alza Corporation	Dispensing system with means for increasing delivery of beneficial agent from the system
US5000957A (en) *	1984-03-19	1991-03-19	Alza Corporation	Dispenser comprising hydrophilic osmopolymer
US4844984A (en) *	1984-03-19	1989-07-04	Alza Corporation	Dispensing system with means for increasing delivery of beneficial agent from the system
US4595583A (en) *	1984-03-19	1986-06-17	Alza Corporation	Delivery system controlled administration of beneficial agent to ruminants
US4729793A (en) *	1985-08-09	1988-03-08	Alza Corporation	Composition for manufacturing wall of dispensing device
US4717566A (en) *	1984-03-19	1988-01-05	Alza Corporation	Dosage system and method of using same
US4772474A (en) *	1985-08-09	1988-09-20	Alza Corporation	Dispenser with internal arrangement of lamina means for dispensing beneficial agent
US4927633A (en) *	1984-03-19	1990-05-22	Alza Corporation	Dispenser for delivering drug to livestock
US4692326A (en) *	1984-03-21	1987-09-08	Alza Corporation	Dispenser comprising inner positioned soft or hard capsule
US4663149A (en) *	1984-03-21	1987-05-05	Alza Corporation	Dispenser comprising inner and outer walls functioning as cooperative unit
US4814180A (en) *	1984-03-21	1989-03-21	Alza Corporation	Agent dispenser comprising a semipermeable wall surrounding single-piece or two-piece container
GB2155889B (en) *	1984-03-21	1988-03-02	Alza Corp	Dispenser-capsule
US4678467A (en) *	1984-03-21	1987-07-07	Alza Corporation	Dispenser comprising capsule with volume displacing member
US4663148A (en) *	1984-03-21	1987-05-05	Alza Corporation	Dispenser comprising telescopically engaging members
US4716031A (en) *	1984-03-21	1987-12-29	Alza Corporation	Drug dispenser comprising a multiplicity of members acting together for successfully dispensing drug
US4627971A (en) *	1985-04-22	1986-12-09	Alza Corporation	Osmotic device with self-sealing passageway
US4624847A (en) *	1985-04-22	1986-11-25	Alza Corporation	Drug delivery device for programmed delivery of beneficial drug
US4609374A (en) *	1985-04-22	1986-09-02	Alza Corporation	Osmotic device comprising means for governing initial time of agent release therefrom
US4717718A (en) *	1985-08-09	1988-01-05	Alza Corporation	Device for the controlled delivery of a beneficial agent
US4717568A (en) *	1985-08-09	1988-01-05	Alza Corporation	Laminar arrangement for increasing delivery of beneficial agent from dispenser
US4955881A (en) *	1985-08-16	1990-09-11	Alza Corporation	Ruminant dispensing device
US4883667A (en) *	1985-08-16	1989-11-28	Alza Corporation	Process for forming dispensing device
US4704118A (en) *	1985-08-16	1987-11-03	Alza Corporation	Ruminant dispensing device with thermo-activated memory
US4966767A (en) *	1985-08-16	1990-10-30	Alza Corporation	Ruminant dispensing device comprising agent displacement member
US4871544A (en) *	1985-08-16	1989-10-03	Alza Corporation	Ruminant dispensing device
US4643731A (en) *	1985-08-16	1987-02-17	Alza Corporation	Means for providing instant agent from agent dispensing system
US5098425A (en) *	1985-08-16	1992-03-24	Alza Corporation	Method of administering a ruminant dispensing device comprising density member dispersed in hydrogel member
US4865598A (en) *	1985-08-16	1989-09-12	Alza Corporation	Dispensing system for administering beneficial agent
US4963141A (en) *	1985-08-16	1990-10-16	Alza Corporation	Dispensing system for administering beneficial agent formulation to ruminants
US4866040A (en) *	1986-01-06	1989-09-12	Alfred Stracher	Aminocarnitine directed pharmaceutical agents
US5008288A (en) *	1986-01-06	1991-04-16	Alfred Stracher	Carnitine directed pharmaceutical agents
US4867969A (en) *	1986-02-07	1989-09-19	Alza Corporation	Hydrogel formulation for administering non-steroidal drugs
US4747847A (en) *	1986-02-07	1988-05-31	Alza Corporation	System for delivering potassium chloride with enhanced bioacceptability
US4723957A (en) *	1986-02-07	1988-02-09	Alza Corp.	System for delivering drug with enhanced bioacceptability
US4971790A (en) *	1986-02-07	1990-11-20	Alza Corporation	Dosage form for lessening irritation of mocusa
US4865845A (en) *	1986-03-21	1989-09-12	Alza Corporation	Release rate adjustment of osmotic or diffusional delivery devices
US4863456A (en) *	1986-04-30	1989-09-05	Alza Corporation	Dosage form with improved delivery capability
GB2189702B (en) *	1986-04-30	1989-10-18	Alza Corp	Dosage form with improved delivery capability
US4960416A (en) *	1986-04-30	1990-10-02	Alza Corporation	Dosage form with improved delivery capability
US4723958A (en) *	1986-05-23	1988-02-09	Merck & Co., Inc.	Pulsatile drug delivery system
US4755180A (en) *	1986-06-16	1988-07-05	Alza Corporation	Dosage form comprising solubility regulating member
US4983400A (en) *	1986-06-16	1991-01-08	Merck & Co., Inc.	Controlled release combination of carbidopa/levodopa
CH668187A5 (de) *	1986-08-07	1988-12-15	Ciba Geigy Ag	Therapeutisches system mit systemischer wirkung.
USRE34990E (en) *	1986-08-07	1995-07-04	Ciba-Geigy Corporation	Oral therapeutic system having systemic action
DE3868077D1 (de) *	1987-01-14	1992-03-12	Ciba Geigy Ag	Therapeutisches system fuer schwerloesliche wirkstoffe.
JPS63180224A (ja) *	1987-01-21	1988-07-25	Matsushita Electric Ind Co Ltd	無線機のアンテナ回路
US4940465A (en) *	1987-05-27	1990-07-10	Felix Theeuwes	Dispenser comprising displaceable matrix with solid state properties
US4892778A (en) *	1987-05-27	1990-01-09	Alza Corporation	Juxtaposed laminated arrangement
US5236689A (en) *	1987-06-25	1993-08-17	Alza Corporation	Multi-unit delivery system
US5340590A (en) *	1987-06-25	1994-08-23	Alza Corporation	Delivery system with bilayer osmotic engine
US5391381A (en) *	1987-06-25	1995-02-21	Alza Corporation	Dispenser capable of delivering plurality of drug units
US5938654A (en) *	1987-06-25	1999-08-17	Alza Corporation	Osmotic device for delayed delivery of agent
US4876093A (en) *	1987-07-02	1989-10-24	Alza Corporation	Dispenser with dispersing member for delivering beneficial agent
US4824675A (en) *	1987-07-13	1989-04-25	Alza Corporation	Dispenser with movable matrix comprising a plurality of tiny pills
US4915949A (en) *	1987-07-13	1990-04-10	Alza Corporation	Dispenser with movable matrix comprising a plurality of tiny pills
US4891223A (en) *	1987-09-03	1990-01-02	Air Products And Chemicals, Inc.	Controlled release delivery coating formulation for bioactive substances
US4946687A (en) *	1987-10-02	1990-08-07	Alza Corporation	Dosage form for treating cardiovascular diseases
US4816263A (en) *	1987-10-02	1989-03-28	Alza Corporation	Dosage form for treating cardiovascular diseases comprising isradipine
US4950486A (en) *	1987-10-02	1990-08-21	Alza Corporation	Dosage form for treating cardiovascular diseases
US4959218A (en) *	1988-03-25	1990-09-25	Alza Corporation	Method for delivering somatotropin to an animal
US4855141A (en) *	1988-03-25	1989-08-08	Alza Corporation	Device comprising means for protecting and dispensing fluid sensitive medicament
US4996060A (en) *	1988-03-25	1991-02-26	Alza Corporation	Device comprising liner for protecting fluid sensitive medicament
US5019397A (en) *	1988-04-21	1991-05-28	Alza Corporation	Aqueous emulsion for pharmaceutical dosage form
US5024842A (en) *	1988-04-28	1991-06-18	Alza Corporation	Annealed coats
US5006346A (en) *	1988-04-28	1991-04-09	Alza Corporation	Delivery system
US4931285A (en) *	1988-04-28	1990-06-05	Alza Corporation	Aqueous based pharmaceutical coating composition for dosage forms
US5030456A (en) *	1988-11-07	1991-07-09	Alza Corporation	Dosage form for treating cardiovascular diseases
US4997658A (en) *	1988-11-21	1991-03-05	Merck & Co., Inc.	Method for enhancing the lowering of plasma cholesterol levels
US5376383A (en) *	1988-11-21	1994-12-27	Merck & Co., Inc.	Method for enhancing the lowering of plasma-cholesterol levels
US5110596A (en) *	1988-12-13	1992-05-05	Alza Corporation	Delivery system comprising means for delivering agent to livestock
US5135523A (en) *	1988-12-13	1992-08-04	Alza Corporation	Delivery system for administering agent to ruminants and swine
US5174999A (en) *	1988-12-13	1992-12-29	Alza Corporation	Delivery system comprising fluid ingress and drug egress
US5037420A (en) *	1988-12-13	1991-08-06	Alza Corporation	Delivery system comprising two sections for delivering somatotropin
US5034229A (en)	1988-12-13	1991-07-23	Alza Corporation	Dispenser for increasing feed conversion of hog
US5728088A (en) *	1988-12-13	1998-03-17	Alza Corporation	Osmotic system for delivery of fluid-sensitive somatotropins to bovine animals
US5059423A (en) *	1988-12-13	1991-10-22	Alza Corporation	Delivery system comprising biocompatible beneficial agent formulation
US5057318A (en) *	1988-12-13	1991-10-15	Alza Corporation	Delivery system for beneficial agent over a broad range of rates
US5030452A (en) *	1989-01-12	1991-07-09	Pfizer Inc.	Dispensing devices powered by lyotropic liquid crystals
US5108756A (en) *	1989-01-12	1992-04-28	Pfizer Inc.	Dispensing devices powered by lyotropic liquid crystals
IL92966A (en) *	1989-01-12	1995-07-31	Pfizer	Dispensing devices powered by hydrogel
DD295760A5 (de) *	1989-01-31	1991-11-14	Martin-Luther-Universitaet Halle Wittenberg,De	Arzneistoffreigabesystem mit kotrollierter wirkstoffreisetzung
FI900470A7 (fi) *	1989-01-31	1990-08-01	Ipa Int Pharma Agentur Gmbh	Aktiiviaineita säädetysti vapauttava systeemi ja menetelmä sen valmistamiseksi
US6200600B1 (en) *	1989-02-16	2001-03-13	Btg International Limited	Controlled delay release device
US5181505A (en) *	1989-03-08	1993-01-26	Lew Chel W	Method and apparatus for delivery of a medicament in the oral cavity
US5002540A (en) *	1989-05-22	1991-03-26	Warren Kirschbaum	Intravaginal device and method for delivering a medicament
US5021053A (en) *	1989-07-14	1991-06-04	Alza Corporation	Oral osmotic device with hydrogel driving member
US5776493A (en) *	1989-07-14	1998-07-07	Alza Corporation	Oral osmotic device for delivery of nystatin with hydrogel driving member
US5126142A (en) *	1989-07-18	1992-06-30	Alza Corporation	Dispenser comprising ionophore
US5273752A (en) *	1989-07-18	1993-12-28	Alza Corporation	Controlled release dispenser comprising beneficial agent
US5035897A (en) *	1989-09-05	1991-07-30	Alza Corporation	Dosage form for delivering soluble or insoluble drugs
US5120548A (en) *	1989-11-07	1992-06-09	Merck & Co., Inc.	Swelling modulated polymeric drug delivery device
US5098714A (en) *	1989-11-16	1992-03-24	Alza Corporation	Osmotic, oral dosage form for fertility control
US5030216A (en) *	1989-12-15	1991-07-09	Alza Corporation	Osmotically driven syringe
US5660851A (en) *	1989-12-26	1997-08-26	Yissum Research Development Company Of The Hebrew Univ. Of Jerusalem	Ocular inserts
US5223266A (en) *	1990-01-24	1993-06-29	Alza Corporation	Long-term delivery device with early startup
US5474785A (en) *	1990-01-24	1995-12-12	Alza Corporation	Delivery system comprising means for controlling internal pressure
US5057321A (en) *	1990-06-13	1991-10-15	Alza Corporation	Dosage form comprising drug and maltodextrin
US5128145A (en) *	1990-06-13	1992-07-07	Alza Corporation	Dosage form for Parkinson's disease, spasticity and muscle spasms
US5234693A (en) *	1990-07-11	1993-08-10	Alza Corporation	Delivery device with a protective sleeve
US5238687A (en) *	1990-07-11	1993-08-24	Alza Corporation	Delivery device with a protective sleeve
US5234692A (en) *	1990-07-11	1993-08-10	Alza Corporation	Delivery device with a protective sleeve
US5180591A (en) *	1990-07-11	1993-01-19	Alza Corporation	Delivery device with a protective sleeve
US5234694A (en) *	1990-07-11	1993-08-10	Alza Corporation	Method for increasing feed efficiency in animals
NZ238867A (en) *	1990-07-12	1993-08-26	Alza Corp	Dosage form for delayed release comprising pharmaceutically active substance and a drug-release hindering means and a second composition which imbibes fluid, expands, and ejects the active substance from the device
US5147654A (en) *	1990-07-23	1992-09-15	Alza Corporation	Oral osmotic device for delivering nicotine
ES2053339T3 (es) *	1990-09-28	1994-07-16	Pfizer	Dispositivo dispensador conteniendo un medio hidrofobo.
US5443459A (en) *	1991-01-30	1995-08-22	Alza Corporation	Osmotic device for delayed delivery of agent
US5378475A (en) *	1991-02-21	1995-01-03	University Of Kentucky Research Foundation	Sustained release drug delivery devices
US5593852A (en)	1993-12-02	1997-01-14	Heller; Adam	Subcutaneous glucose electrode
US5861166A (en) *	1991-03-12	1999-01-19	Alza Corporation	Delivery device providing beneficial agent stability
US5208037A (en) *	1991-04-22	1993-05-04	Alza Corporation	Dosage forms comprising polymers comprising different molecular weights
US5198229A (en) *	1991-06-05	1993-03-30	Alza Corporation	Self-retaining gastrointestinal delivery device
US5137727A (en) *	1991-06-12	1992-08-11	Alza Corporation	Delivery device providing beneficial agent stability
US5190765A (en) *	1991-06-27	1993-03-02	Alza Corporation	Therapy delayed
US6764697B1 (en)	1991-06-27	2004-07-20	Alza Corporation	System for delaying drug delivery up to seven hours
US5160744A (en) *	1991-06-27	1992-11-03	Alza Corporation	Verapmil therapy
US5252338A (en) *	1991-06-27	1993-10-12	Alza Corporation	Therapy delayed
US5178867A (en) *	1991-08-19	1993-01-12	Alza Corporation	Dosage form for delivering drug in short-time period
US5240713A (en) *	1991-09-27	1993-08-31	Alza Corporation	Dual rate agent delivery device
CA2115648C (en) *	1991-10-10	2002-04-09	Eun Soo Lee	Osmotic drug delivery devices with hydrophobic wall materials
US5254349A (en) *	1991-12-06	1993-10-19	Alza Corporation	Process for lessening irritation caused by drug
US5200195A (en) *	1991-12-06	1993-04-06	Alza Corporation	Process for improving dosage form delivery kinetics
US5266332A (en) *	1991-12-06	1993-11-30	Alza Corporation	Method for administering anti-Parkinson drug
US5200194A (en) *	1991-12-18	1993-04-06	Alza Corporation	Oral osmotic device
US5543154A (en) *	1991-12-27	1996-08-06	Merck & Co., Inc.	Controlled release nifedipine delivery device
US5223265A (en) *	1992-01-10	1993-06-29	Alza Corporation	Osmotic device with delayed activation of drug delivery
US5246711A (en) *	1992-02-27	1993-09-21	Alza Corporation	Dosage form for treating dysthymia
US5330762A (en) *	1992-02-27	1994-07-19	Alza Corporation	Tandospiaine antidepressive therapy
US5246710A (en) *	1992-02-27	1993-09-21	Alza Corporation	Dosage form for treating cyclothymia
US5858407A (en) *	1992-02-27	1999-01-12	Alza Corporation	Method for administering tandospirone
US5185158A (en) *	1992-02-27	1993-02-09	Alza Corporation	Dosage form comprising succinimide drug for treating depressive disorders and composition comprising same
US5688518A (en) *	1992-02-27	1997-11-18	Alza Corporation	Antidepressive therapy
US5248310A (en) *	1992-03-27	1993-09-28	Alza Corporation	Oral osmotic device with hydrogel driving member
US5512299A (en) *	1992-03-30	1996-04-30	Alza Corporation	Method of treating oral inflammatory disease
US5869097A (en)	1992-11-02	1999-02-09	Alza Corporation	Method of therapy comprising an osmotic caplet
US5573776A (en) *	1992-12-02	1996-11-12	Alza Corporation	Oral osmotic device with hydrogel driving member
US5358721A (en) *	1992-12-04	1994-10-25	Alza Corporation	Antiviral therapy
US6440457B1 (en) *	1993-05-27	2002-08-27	Alza Corporation	Method of administering antidepressant dosage form
US6287598B1 (en) *	1993-05-28	2001-09-11	Alza Corporation	Method for providing sustained antiepileptic therapy
US5498255A (en) *	1993-08-17	1996-03-12	Alza Corporation	Osmotic device for protracted pulsatile delivery of agent
HU213407B (en) *	1993-12-09	1997-06-30	Egyt Gyogyszervegyeszeti Gyar	Process for producing tablet with diffusive-osmotic release
US5474985A (en) *	1993-12-22	1995-12-12	The Regents Of The University Of California	Preventing and treating elevated intraocular pressure associated with administered or endogenous steroids using non-steroidal cyclooxygenase inhibitors
GB9326267D0 (en) *	1993-12-23	1994-02-23	Scherer Corp R P	Expulsion of material
US5532003A (en) *	1994-01-18	1996-07-02	Alza Corporation	Pentoxifylline therapy
US5540665A (en) *	1994-01-31	1996-07-30	Alza Corporation	Gas driven dispensing device and gas generating engine therefor
US20040191314A1 (en) *	1994-04-28	2004-09-30	Frank Jao	Antiepileptic dosage form and process for protecting antiepileptic drug
ZA953078B (en) *	1994-04-28	1996-01-05	Alza Corp	Effective therapy for epilepsies
US5698224A (en) *	1994-06-27	1997-12-16	Alza Corporation	Tacrine therapy
US5460826A (en) *	1994-06-27	1995-10-24	Alza Corporation	Morphine therapy
US5529787A (en) *	1994-07-07	1996-06-25	Alza Corporation	Hydromorphone therapy
US5914131A (en) *	1994-07-07	1999-06-22	Alza Corporation	Hydromorphone therapy
US5633011A (en) *	1994-08-04	1997-05-27	Alza Corporation	Progesterone replacement therapy
IE70735B1 (en) *	1994-08-15	1996-12-11	Elan Med Tech	Orally administrable delivery device
US5837276A (en)	1994-09-02	1998-11-17	Delab	Apparatus for the delivery of elongate solid drug compositions
US5582591A (en) *	1994-09-02	1996-12-10	Delab	Delivery of solid drug compositions
US6491945B1 (en) *	1994-09-16	2002-12-10	Alza Corporation	Hydrocodone therapy
US5614578A (en) *	1994-10-28	1997-03-25	Alza Corporation	Injection-molded dosage form
US5582838A (en) *	1994-12-22	1996-12-10	Merck & Co., Inc.	Controlled release drug suspension delivery device
US5534263A (en) *	1995-02-24	1996-07-09	Alza Corporation	Active agent dosage form comprising a matrix and at least two insoluble bands
US5876741A (en) *	1995-03-30	1999-03-02	Medlogic Global Corporation	Chemo-mechanical expansion delivery system
US5651979A (en) *	1995-03-30	1997-07-29	Gel Sciences, Inc.	Apparatus and method for delivering a biologically active compound into a biological environment
SI9500173B (sl) *	1995-05-19	2002-02-28	Lek,	Trofazna farmacevtska oblika s konstantnim in kontroliranim sproščanjem amorfne učinkovine za enkrat dnevno aplikacijo
US5674895A (en) *	1995-05-22	1997-10-07	Alza Corporation	Dosage form comprising oxybutynin
US6124355A (en) *	1995-05-22	2000-09-26	Guittard; George V.	Oxybutynin therapy
US5912268A (en) *	1995-05-22	1999-06-15	Alza Corporation	Dosage form and method for treating incontinence
US6262115B1 (en)	1995-05-22	2001-07-17	Alza Coporation	Method for the management of incontinence
US5817335A (en) *	1995-05-26	1998-10-06	Alza Corporation	Osmotic device with high drug loading and delayed activation of drug delivery
US20060280774A1 (en) *	1995-06-02	2006-12-14	Allergan, Inc.	Compositions and methods for treating glaucoma
US5800422A (en) *	1995-06-02	1998-09-01	Alza Corporation	Osmotic device with delayed activation of drug delivery and complete drug release
US5869079A (en) *	1995-06-02	1999-02-09	Oculex Pharmaceuticals, Inc.	Formulation for controlled release of drugs by combining hydrophilic and hydrophobic agents
US5599535A (en) *	1995-06-07	1997-02-04	Regents Of The University Of California	Methods for the cyto-protection of the trabecular meshwork
US5713852A (en) *	1995-06-07	1998-02-03	Alza Corporation	Oral dosage and method for treating painful conditions of the oral cavity
US5690952A (en) *	1995-06-07	1997-11-25	Judy A. Magruder et al.	Implantable system for delivery of fluid-sensitive agents to animals
US5674888A (en) *	1995-06-07	1997-10-07	University Of California	Method for the treatment of a trabecular meshwork whose cells are subject to inhibition of cell division
US5731001A (en) *	1995-06-07	1998-03-24	Magruder; Judy A.	Locking couplings for osmotic delivery devices
US5780058A (en)	1995-07-21	1998-07-14	Alza Corporation	Oral delivery of discrete units
US5840332A (en) *	1996-01-18	1998-11-24	Perio Products Ltd.	Gastrointestinal drug delivery system
ES2168610T3 (es) *	1996-03-12	2002-06-16	Alza Corp	Composicion y forma galenica que contiene un antagonista opioide.
ZA97976B (en) *	1996-04-05	1997-08-18	Alza Corp	Uniform drug delivery theraphy.
US6096339A (en) *	1997-04-04	2000-08-01	Alza Corporation	Dosage form, process of making and using same
US5902605A (en) *	1996-04-18	1999-05-11	Alza Corporation	Drug delivery device with minimal residual drug retention
PT957899E (pt) *	1996-08-16	2003-07-31	Alza Corp	Forma de dosagem para proporcionar um medicamento numa dose crescente
DK0936893T3 (da) *	1996-10-18	2001-09-03	Alza Corp	Indretning med flere strømningsbaner til oral afgivelse af diskrete enheder
AU729769B2 (en) *	1996-10-18	2001-02-08	Alza Corporation	Closure system for an active agent delivery device
US6024721A (en)	1996-10-18	2000-02-15	Alza Corporation	Mixing system for an active agent delivery device
CA2269707C (en) *	1996-10-25	2005-08-16	Edward M. Rudnic	Soluble form osmotic dose delivery system
US6361796B1 (en) *	1996-10-25	2002-03-26	Shire Laboratories, Inc.	Soluble form osmotic dose delivery system
US6919373B1 (en) *	1996-11-12	2005-07-19	Alza Corporation	Methods and devices for providing prolonged drug therapy
EP1782798A3 (de)	1996-11-25	2008-05-21	Alza Corporation	Darreichungsform mit ansteigender Dosisfreisetzung
CN100477986C (zh) *	1996-11-25	2009-04-15	阿尔萨公司	递增剂量的剂型
US5788987A (en)	1997-01-29	1998-08-04	Poli Industria Chimica Spa	Methods for treating early morning pathologies
US5837379A (en) *	1997-01-31	1998-11-17	Andrx Pharmaceuticals, Inc.	Once daily pharmaceutical tablet having a unitary core
US5922352A (en) *	1997-01-31	1999-07-13	Andrx Pharmaceuticals, Inc.	Once daily calcium channel blocker tablet having a delayed release core
US20030100532A1 (en)	1997-02-14	2003-05-29	Gary S. Jacob	Use of n-substituted-1,5-dideoxy-1,5-imino-d-glucitol compounds in combination therapy for treating hepatitis virus infections
US5948787A (en) *	1997-02-28	1999-09-07	Alza Corporation	Compositions containing opiate analgesics
US7885697B2 (en)	2004-07-13	2011-02-08	Dexcom, Inc.	Transcutaneous analyte sensor
ES2182303T3 (es) *	1997-05-16	2003-03-01	Alza Corp	Configuraciones reguladoras del flujo para un dispositivo de administracion de agents activos.
US6110499A (en) *	1997-07-24	2000-08-29	Alza Corporation	Phenytoin therapy
US5902598A (en) *	1997-08-28	1999-05-11	Control Delivery Systems, Inc.	Sustained release drug delivery devices
US6514530B2 (en)	1997-09-09	2003-02-04	Alza Corporation	Dosage form comprising means for changing drug delivery shape
US7060734B1 (en)	1997-09-09	2006-06-13	Alza Corporation	Pharmaceutical coating composition and method of use
PT1014951E (pt)	1997-09-09	2005-03-31	Alza Corp	Composicao de revestimento farmaceutica e metodo para a sua utilizacao
US20040062799A1 (en) *	1997-09-29	2004-04-01	Ayer Atul D.	Therapeutic composition and delivery system for administering drug
ZA9810210B (en)	1997-11-10	1999-07-14	Searle & Co	Use of alkylated iminosugars to treat multidrug resistance.
WO1999029297A1 (en)	1997-12-05	1999-06-17	Alza Corporation	Osmotic dosage form comprising first and second coats
US6485748B1 (en)	1997-12-12	2002-11-26	Andrx Pharmaceuticals, Inc.	Once daily pharmaceutical tablet having a unitary core
KR100576583B1 (ko)	1997-12-22	2006-05-04	알자 코포레이션	서방성 약물 송달 장치용 속도 조절막
US6689759B1 (en)	1998-02-12	2004-02-10	G. D. Searle & Co.	Methods of Treating hepatitis virus infections with N-substituted-1,5-dideoxy-1,5-imino-d-glucitol compounds in combination therapy
KR20010040937A (ko)	1998-02-12	2001-05-15	윌리암스 로저 에이	간염 바이러스 감염의 치료를 위한 ｎ-치환된1,5-디데옥시-1,5-이미노-ｄ-글루시톨 화합물의 용도
US6134461A (en)	1998-03-04	2000-10-17	E. Heller & Company	Electrochemical analyte
US8524277B2 (en) *	1998-03-06	2013-09-03	Alza Corporation	Extended release dosage form
US6245357B1 (en)	1998-03-06	2001-06-12	Alza Corporation	Extended release dosage form
US6099859A (en) *	1998-03-20	2000-08-08	Andrx Pharmaceuticals, Inc.	Controlled release oral tablet having a unitary core
AR018321A1 (es) *	1998-03-26	2001-11-14	Alza Corp	Una forma de dosificacion de liberacion prolongada que comprende oxibutinina y los usos de la oxibutinina y de la forma de dosificacion de liberacionprolongada.
US8465425B2 (en)	1998-04-30	2013-06-18	Abbott Diabetes Care Inc.	Analyte monitoring device and methods of use
US8346337B2 (en)	1998-04-30	2013-01-01	Abbott Diabetes Care Inc.	Analyte monitoring device and methods of use
US6949816B2 (en)	2003-04-21	2005-09-27	Motorola, Inc.	Semiconductor component having first surface area for electrically coupling to a semiconductor chip and second surface area for electrically coupling to a substrate, and method of manufacturing same
US8480580B2 (en)	1998-04-30	2013-07-09	Abbott Diabetes Care Inc.	Analyte monitoring device and methods of use
US9066695B2 (en)	1998-04-30	2015-06-30	Abbott Diabetes Care Inc.	Analyte monitoring device and methods of use
US8974386B2 (en)	1998-04-30	2015-03-10	Abbott Diabetes Care Inc.	Analyte monitoring device and methods of use
US6175752B1 (en)	1998-04-30	2001-01-16	Therasense, Inc.	Analyte monitoring device and methods of use
US8688188B2 (en)	1998-04-30	2014-04-01	Abbott Diabetes Care Inc.	Analyte monitoring device and methods of use
US6365183B1 (en) *	1998-05-07	2002-04-02	Alza Corporation	Method of fabricating a banded prolonged release active agent dosage form
KR100827254B1 (ko)	1998-06-03	2008-05-07	알자 코포레이션	연장된 약물 치료를 제공하기 위한 방법 및 장치
US20010038855A1 (en) *	1998-06-05	2001-11-08	Desjardin Michael A.	Dosage form for administering prescribed dose
US7890176B2 (en) *	1998-07-06	2011-02-15	Boston Scientific Neuromodulation Corporation	Methods and systems for treating chronic pelvic pain
US6524620B2 (en)	1998-07-20	2003-02-25	Andrx Pharmaceuticals, Inc.	Diltiazem controlled release formulation and method of manufacture
US20050158408A1 (en) *	1998-07-24	2005-07-21	Yoo Seo H.	Dried forms of aqueous solubilized bile acid dosage formulation: preparation and uses thereof
US7772220B2 (en) *	2004-10-15	2010-08-10	Seo Hong Yoo	Methods and compositions for reducing toxicity of a pharmaceutical compound
ATE292956T1 (de)	1998-07-24	2005-04-15	Seo Hong Yoo	Klare wässrige lösungen enthaltend gallensäuren
US7303768B2 (en) *	1998-07-24	2007-12-04	Seo Hong Yoo	Preparation of aqueous clear solution dosage forms with bile acids
HK1038508B (en) *	1998-09-09	2006-06-30	Alza Corporation	Dosage form comprising liquid formulation
DE19842753A1 (de)	1998-09-18	2000-03-23	Bayer Ag	Agitationsunabhängige pharmazeutische Retardzubereitungen und Verfahren zu ihrer Herstellung
US6531152B1 (en)	1998-09-30	2003-03-11	Dexcel Pharma Technologies Ltd.	Immediate release gastrointestinal drug delivery system
US6087396A (en) *	1998-10-05	2000-07-11	Situs Corporation	Oxybutynin formulations and method of use
GB9822854D0 (en)	1998-10-21	1998-12-16	Reckitt & Colmann Prod Ltd	Improvements in or relating to organic compositions
DK1140012T3 (da) *	1998-12-17	2004-07-12	Alza Corp	Omdannelse af væskefyldte gelatinekapsler til systemer til kontrolleret frigivelsessystemer ved flere coatinger
HK1040915B (en)	1998-12-18	2010-05-07	Alza Corporation	Transparent transdermal nicotine delivery devices
US6797283B1 (en)	1998-12-23	2004-09-28	Alza Corporation	Gastric retention dosage form having multiple layers
EP1154691A4 (de) *	1999-01-05	2004-07-07	Massachusetts Eye & Ear Infirm	Gezielte transsklerale gesteuerte wirkstoffabgabe an die retina und choroidae
DE60042352D1 (de) *	1999-02-10	2009-07-23	Pfizer Prod Inc	Osmotisches System zur Verabreichung von Wirkstoffen, die feste amorphe Dispersionen enthalten
US6706283B1 (en) *	1999-02-10	2004-03-16	Pfizer Inc	Controlled release by extrusion of solid amorphous dispersions of drugs
CA2362785A1 (en)	1999-02-12	2001-02-08	G.D. Searle & Co.	Glucamine compounds for treating hepatitis virus infections
JP2002536407A (ja) *	1999-02-12	2002-10-29	ジー・ディー・サール・アンド・カンパニー	肝炎ウィルス感染の治療のための置換−１，５−ジデオキシ−１，５−イミノ−ｄ−グルシトール化合物の使用
US6198966B1 (en)	1999-02-26	2001-03-06	Medtronic, Inc.	Recirculating implantable drug delivery system
US8545880B2 (en) *	1999-02-26	2013-10-01	Andrx Pharmaceuticals, Llc	Controlled release oral dosage form
US6210716B1 (en)	1999-02-26	2001-04-03	Andrx Pharmaceuticals, Inc.	Controlled release bupropion formulation
US6835194B2 (en)	1999-03-18	2004-12-28	Durect Corporation	Implantable devices and methods for treatment of pain by delivery of fentanyl and fentanyl congeners
US6541021B1 (en)	1999-03-18	2003-04-01	Durect Corporation	Devices and methods for pain management
US20040121014A1 (en) *	1999-03-22	2004-06-24	Control Delivery Systems, Inc.	Method for treating and/or preventing retinal diseases with sustained release corticosteroids
US6217895B1 (en) *	1999-03-22	2001-04-17	Control Delivery Systems	Method for treating and/or preventing retinal diseases with sustained release corticosteroids
US6217896B1 (en) *	1999-04-01	2001-04-17	Uab Research Foundation	Conjunctival inserts for topical delivery of medication or lubrication
US6632451B2 (en)	1999-06-04	2003-10-14	Dexcel Pharma Technologies Ltd.	Delayed total release two pulse gastrointestinal drug delivery system
US6287870B1 (en) *	1999-08-20	2001-09-11	Robert A. Levine	Method and assembly for separating formed constituents from a liquid constituent in a complex biologic fluid sample
US6387403B1 (en)	1999-09-15	2002-05-14	Alza Corporation	Dosage forms and methods for providing effective reboxetine therapy with once-a-day dosing
US6387325B1 (en) *	1999-10-08	2002-05-14	Becton Dickinson & Company	Assembly for separating formed constituents from a liquid constituent in a complex biologic fluid sample
DE60040876D1 (de)	1999-10-21	2009-01-02	Alcon Inc	Medikamentenzuführeinrichtung
US7943162B2 (en) *	1999-10-21	2011-05-17	Alcon, Inc.	Drug delivery device
WO2001028473A1 (en)	1999-10-21	2001-04-26	Alcon Universal Ltd.	Sub-tenon drug delivery
US6416777B1 (en) *	1999-10-21	2002-07-09	Alcon Universal Ltd.	Ophthalmic drug delivery device
US7108866B1 (en)	1999-12-10	2006-09-19	Biovall Laboratories International Srl	Chronotherapeutic diltiazem formulations and the administration thereof
US20060153914A1 (en) *	1999-12-10	2006-07-13	Biovail Laboratories International S.R.L.	Chronotherapeutic diltiazem formulations and the administration thereof
EP1239839A2 (de)	1999-12-23	2002-09-18	Pfizer Products Inc.	Durch hydrogel gesteuerte mehrschichtige dosierungsform enthaltend sertralin
AU783685B2 (en)	1999-12-23	2005-11-24	Pfizer Products Inc.	Hydrogel-driven drug dosage form
DE19962924A1 (de)	1999-12-24	2001-07-05	Bayer Ag	Substituierte Oxazolidinone und ihre Verwendung
US6669954B2 (en)	2000-01-25	2003-12-30	John R. Crison	Controlled release of drugs
JP2004500378A (ja) *	2000-02-04	2004-01-08	ヨー、セオ、ホン	胆汁酸を含有する清浄水溶液製型の製造
CN1422156A (zh) *	2000-02-14	2003-06-04	法马西亚公司	N－取代的－1,5－二脱氧－1,5－亚氨基－d－葡萄糖醇化合物在治疗肝炎病毒感染中的用途
US6464688B1 (en)	2000-02-15	2002-10-15	Microsolutions, Inc.	Osmotic pump delivery system with flexible drug compartment
US6544555B2 (en)	2000-02-24	2003-04-08	Advancis Pharmaceutical Corp.	Antibiotic product, use and formulation thereof
US6582441B1 (en)	2000-02-24	2003-06-24	Advanced Bionics Corporation	Surgical insertion tool
US6855703B1 (en)	2000-03-10	2005-02-15	Endeavor Pharmaceuticals	Pharmaceutical compositions of conjugated estrogens and methods of analyzing mixtures containing estrogenic compounds
US7989436B2 (en) *	2003-07-23	2011-08-02	Duramed Pharmaceuticals, Inc.	Estrogenic compounds and pharmaceutical formulations comprising the same
US7459445B2 (en) *	2000-03-10	2008-12-02	Duramed Pharmaceuticals, Inc.	Estrogenic compounds and topical pharmaceutical formulations of the same
US7074803B2 (en) *	2001-03-02	2006-07-11	Durect Corporation	Opioid formulations
US6660726B2 (en)	2000-03-10	2003-12-09	Endeavor Pharmaceuticals	Estrogenic compounds, pharmaceutical compositions thereof, and methods of using same
US6375972B1 (en)	2000-04-26	2002-04-23	Control Delivery Systems, Inc.	Sustained release drug delivery devices, methods of use, and methods of manufacturing thereof
AU2001257359A1 (en)	2000-04-27	2001-11-07	Verion Inc.	Zero order release and temperature-controlled microcapsules and process for the preparation thereof
US6726918B1 (en)	2000-07-05	2004-04-27	Oculex Pharmaceuticals, Inc.	Methods for treating inflammation-mediated conditions of the eye
US20030086972A1 (en) *	2000-08-09	2003-05-08	Appel Leah E.	Hydrogel-driven drug dosage form
US20020068078A1 (en)	2000-10-13	2002-06-06	Rudnic Edward M.	Antifungal product, use and formulation thereof
AU3649502A (en)	2000-11-29	2002-06-11	Oculex Pharm Inc	Methods for reducing or preventing transplant rejection in the eye and intraocular implants for use therefor
JP4248236B2 (ja) *	2000-11-29	2009-04-02	デュレクトコーポレイション	薬物送達装置からの送達を制御するための装置および方法
US6560471B1 (en)	2001-01-02	2003-05-06	Therasense, Inc.	Analyte monitoring device and methods of use
US7493172B2 (en) *	2001-01-30	2009-02-17	Boston Scientific Neuromodulation Corp.	Methods and systems for stimulating a nerve originating in an upper cervical spine area to treat a medical condition
US20060064140A1 (en) *	2001-01-30	2006-03-23	Whitehurst Todd K	Methods and systems for stimulating a trigeminal nerve to treat a psychiatric disorder
US20050143789A1 (en) *	2001-01-30	2005-06-30	Whitehurst Todd K.	Methods and systems for stimulating a peripheral nerve to treat chronic pain
IN190699B (de)	2001-02-02	2003-08-16	Sun Pharmaceutical Ind Ltd
WO2002074285A1 (en) *	2001-03-16	2002-09-26	Andrx Corporation	Controlled release sulfonylurea formulation
WO2002078512A2 (en)	2001-04-02	2002-10-10	Therasense, Inc.	Blood glucose tracking apparatus and methods
US6632217B2 (en)	2001-04-19	2003-10-14	Microsolutions, Inc.	Implantable osmotic pump
UA81224C2 (uk) *	2001-05-02	2007-12-25	Euro Celtic S A	Дозована форма оксикодону та її застосування
US20110104214A1 (en)	2004-04-15	2011-05-05	Purdue Pharma L.P.	Once-a-day oxycodone formulations
JP2004536631A (ja)	2001-05-03	2004-12-09	マサチューセッツ・アイ・アンド・イア・インファーマリー	移植可能な薬物送達デバイスおよびその使用
ATE506929T1 (de)	2001-06-12	2011-05-15	Univ Johns Hopkins Med	Reservoirvorrichtung für die intraokulare arzneimittelabgabe
DE10129725A1 (de) *	2001-06-20	2003-01-02	Bayer Ag	Kombinationstherapie substituierter Oxazolidinone
US20040180087A1 (en) *	2001-06-21	2004-09-16	Boyong Li	Stable controlled release pharmaceutical compositions containing pravastatin
PL204644B1 (pl)	2001-07-23	2010-01-29	Alcon	Okulistyczne urządzenie do podawania leków
DE60214697T2 (de) *	2001-07-23	2007-09-13	Alcon Inc.	Vorrichtung zur freisetzung eines ophthalmischen arzneimittels
US20030091634A1 (en) *	2001-09-14	2003-05-15	Pawan Seth	Delayed release tablet of venlafaxin
CA2461870A1 (en) *	2001-09-28	2003-04-03	Mcneil-Ppc, Inc.	Modified release dosage forms
US20030153864A1 (en) *	2001-10-16	2003-08-14	Bernard Chaffringeon	Disposable device and method for transferring an active liquid into a body cavity
US8329217B2 (en) *	2001-11-06	2012-12-11	Osmotica Kereskedelmi Es Szolgaltato Kft	Dual controlled release dosage form
US20030185882A1 (en) *	2001-11-06	2003-10-02	Vergez Juan A.	Pharmaceutical compositions containing oxybutynin
US7183321B2 (en) *	2001-12-17	2007-02-27	Bristol-Myers Squibb Company	Antidiabetic formulation and method
US20030161882A1 (en) *	2002-02-01	2003-08-28	Waterman Kenneth C.	Osmotic delivery system
TW200302748A (en) *	2002-02-01	2003-08-16	Pfizer Prod Inc	Osmotic delivery system
US8010174B2 (en)	2003-08-22	2011-08-30	Dexcom, Inc.	Systems and methods for replacing signal artifacts in a glucose sensor data stream
US9247901B2 (en)	2003-08-22	2016-02-02	Dexcom, Inc.	Systems and methods for replacing signal artifacts in a glucose sensor data stream
US7613491B2 (en)	2002-05-22	2009-11-03	Dexcom, Inc.	Silicone based membranes for use in implantable glucose sensors
US8364229B2 (en)	2003-07-25	2013-01-29	Dexcom, Inc.	Analyte sensors having a signal-to-noise ratio substantially unaffected by non-constant noise
US8260393B2 (en)	2003-07-25	2012-09-04	Dexcom, Inc.	Systems and methods for replacing signal data artifacts in a glucose sensor data stream
EP2316468A1 (de)	2002-02-22	2011-05-04	Shire LLC	Abgabesystem und Verfahren zum Schutz und zur Verabreichung von Dextroamphetamin
US7514107B2 (en)	2002-03-21	2009-04-07	Mars, Incorporated	Treatment of diseases involving defective gap junctional communication
WO2003086353A1 (en) *	2002-04-05	2003-10-23	Penwest Pharmaceuticals Co.	Sustained release metoprolol formulations
US7125563B2 (en) *	2002-04-12	2006-10-24	Dava Pharmaceuticals, Inc.	Sustained release pharmaceutical preparations and methods for producing the same
US6733526B2 (en)	2002-04-25	2004-05-11	Advanced Medical Optics, Inc.	Method of improving adherence and centering of intra-corneal implants on corneal bed
JP2005525405A (ja) *	2002-04-29	2005-08-25	アルザ・コーポレーシヨン	オキシコドンを制御して補給する方法および剤型
US20050106249A1 (en) *	2002-04-29	2005-05-19	Stephen Hwang	Once-a-day, oral, controlled-release, oxycodone dosage forms
WO2003092665A2 (en) *	2002-05-02	2003-11-13	Massachusetts Eye And Ear Infirmary	Ocular drug delivery systems and use thereof
US7328706B2 (en) *	2002-05-06	2008-02-12	Dynamic Mouth Devices Llc	Therapeutic and protective dental device useful as an intra-oral delivery system
US8871241B2 (en) *	2002-05-07	2014-10-28	Psivida Us, Inc.	Injectable sustained release delivery devices
US7151961B1 (en) *	2002-05-24	2006-12-19	Advanced Bionics Corporation	Treatment of movement disorders by brain stimulation
NZ536693A (en) *	2002-05-31	2007-01-26	Alza Corp	Controlled release dosage forms and compositions for osmotic delivery of variable dosages of oxycodone
US20040043067A1 (en) *	2002-06-19	2004-03-04	Salamone Joseph C.	Fluorosiloxane matrix controlled diffusion drug delivery systems
AR039744A1 (es) *	2002-06-26	2005-03-09	Alza Corp	Metodos y formas de dosificacion para aumentar la solubilidad de las composiciones de farmacos para la administracion controlada
US20040115262A1 (en) *	2002-07-29	2004-06-17	Frank Jao	Formulations and dosage forms for controlled delivery of topiramate
US20040005359A1 (en) *	2002-06-27	2004-01-08	Cheng Xiu Xiu	Controlled release oral dosage form
US20050232995A1 (en) *	2002-07-29	2005-10-20	Yam Nyomi V	Methods and dosage forms for controlled delivery of paliperidone and risperidone
US7254449B2 (en) *	2002-07-31	2007-08-07	Advanced Bionics Corp	Systems and methods for providing power to one or more implantable devices
US20060009739A1 (en) *	2002-09-06	2006-01-12	Durect Corporation	Implantable flow regulator with failsafe mode and reserve drug supply
CA2497867A1 (en)	2002-09-06	2004-03-18	Durect Corporation	Delivery of modulators of glutamate-mediated neurotransmission to the inner ear
AU2003270778B2 (en) *	2002-09-20	2009-10-08	Alpharma Pharmaceuticals, Llc	Sequestering subunit and related compositions and methods
US20050048119A1 (en) *	2002-09-20	2005-03-03	Avinash Nangia	Controlled release composition with semi-permeable membrane and poloxamer flux enhancer
US20050051922A1 (en) *	2002-09-20	2005-03-10	Avinash Nangia	Pharmaceutical composition with sodium lauryl sulfate as an extra-granular absorption/compression enhancer and the process to make the same
AU2003287301A1 (en) *	2002-10-31	2004-06-07	Alza Corporation	Dosage form providing ascending release of liquid formulation
US7381184B2 (en)	2002-11-05	2008-06-03	Abbott Diabetes Care Inc.	Sensor inserter assembly
GB2395126A (en) *	2002-11-09	2004-05-19	Reckitt Benckiser	Volatile substance dispenser
US6893660B2 (en) *	2002-11-21	2005-05-17	Andrx Pharmaceuticals, Inc.	Stable pharmaceutical compositions without a stabilizer
US20040102476A1 (en) *	2002-11-25	2004-05-27	Chan Tai Wah	High concentration formulations of opioids and opioid derivatives
EP1575569B1 (de)	2002-12-13	2010-09-29	Durect Corporation	Orale darreichungsform mit flüssigen hochviskosen trägersystemen
WO2004061420A2 (en)	2002-12-31	2004-07-22	Therasense, Inc.	Continuous glucose monitoring system and methods of use
US8771183B2 (en)	2004-02-17	2014-07-08	Abbott Diabetes Care Inc.	Method and system for providing data communication in continuous glucose monitoring and management system
DE10300111A1 (de) *	2003-01-07	2004-07-15	Bayer Healthcare Ag	Verfahren zur Herstellung von 5-Chlor-N-({(5S)-2-oxo-3-[4-(3-oxo-4-morpholinyl)-phenyl]-1,3-oxazolidin-5-yl}-methyl)-2-thiophencarboxamid
US20050048099A1 (en)	2003-01-09	2005-03-03	Allergan, Inc.	Ocular implant made by a double extrusion process
CA2512786A1 (en) *	2003-01-14	2004-08-05	Alza Corporation	Methods and dosage forms with modified viscosity layers
JP3811127B2 (ja) *	2003-01-30	2006-08-16	株式会社東芝	情報記録装置及び情報記録方法
CA2515641A1 (en) *	2003-02-11	2004-08-26	Alza Corporation	Methods and dosage forms with modified layer geometry
WO2004073551A2 (en) *	2003-02-18	2004-09-02	Massachusetts Eye And Ear Infirmary	Transscleral drug delivery device and related methods
US6992075B2 (en) *	2003-04-04	2006-01-31	Barr Laboratories, Inc.	C(14) estrogenic compounds
CA2521471A1 (en) *	2003-04-11	2004-10-28	Barr Laboratories, Inc.	Methods of administering estrogens and progestins
US20040213850A1 (en) *	2003-04-25	2004-10-28	Eleni Dokou	Sustained release delivery of a thrombin inhibitor
US20070083240A1 (en) *	2003-05-08	2007-04-12	Peterson David K L	Methods and systems for applying stimulation and sensing one or more indicators of cardiac activity with an implantable stimulator
US20070172446A1 (en)	2003-05-16	2007-07-26	Intermune, Inc.	Synthetic chemokine receptor ligands and methods of use thereof
US8066639B2 (en)	2003-06-10	2011-11-29	Abbott Diabetes Care Inc.	Glucose measuring device for use in personal area network
US20040253293A1 (en) *	2003-06-16	2004-12-16	Afshin Shafiee	Rate controlled release of a pharmaceutical agent in a biodegradable device
US7145125B2 (en)	2003-06-23	2006-12-05	Advanced Optical Technologies, Llc	Integrating chamber cone light using LED sources
US8802139B2 (en)	2003-06-26	2014-08-12	Intellipharmaceutics Corp.	Proton pump-inhibitor-containing capsules which comprise subunits differently structured for a delayed release of the active ingredient
JP2007526019A (ja) *	2003-07-10	2007-09-13	アルコン，インコーポレイティド	眼科用薬物送達デバイス
US9763609B2 (en)	2003-07-25	2017-09-19	Dexcom, Inc.	Analyte sensors having a signal-to-noise ratio substantially unaffected by non-constant noise
WO2007120442A2 (en)	2003-07-25	2007-10-25	Dexcom, Inc.	Dual electrode system for a continuous analyte sensor
US7591801B2 (en)	2004-02-26	2009-09-22	Dexcom, Inc.	Integrated delivery device for continuous glucose sensor
US7774145B2 (en)	2003-08-01	2010-08-10	Dexcom, Inc.	Transcutaneous analyte sensor
US20190357827A1 (en)	2003-08-01	2019-11-28	Dexcom, Inc.	Analyte sensor
US8275437B2 (en)	2003-08-01	2012-09-25	Dexcom, Inc.	Transcutaneous analyte sensor
EP1653922A2 (de) *	2003-08-06	2006-05-10	Alza Corporation	Gleichförmige zuführung von topiramat über einen verlängerten zeitraum mit verbesserter dispersionsformulierung
US7920906B2 (en)	2005-03-10	2011-04-05	Dexcom, Inc.	System and methods for processing analyte sensor data for sensor calibration
CA2536507A1 (en) *	2003-08-22	2005-03-10	Alza Corporation	Stepwise delivery of topiramate over prolonged period of time
US20140121989A1 (en)	2003-08-22	2014-05-01	Dexcom, Inc.	Systems and methods for processing analyte sensor data
US20070066873A1 (en) *	2003-08-22	2007-03-22	Apurv Kamath	Systems and methods for processing analyte sensor data
EP1701697A2 (de) *	2003-09-02	2006-09-20	ALZA Corporation	Neue arzneimittelzusammensetzungen und dosierformen von topiramat
US7611728B2 (en) *	2003-09-05	2009-11-03	Supernus Pharmaceuticals, Inc.	Osmotic delivery of therapeutic compounds by solubility enhancement
US20070259033A1 (en)	2003-09-26	2007-11-08	Evangeline Cruz	Controlled release formulations exhibiting an ascending rate of release
WO2005072079A2 (en)	2003-09-26	2005-08-11	Alza Coporation	Drug coating providing high drug loading and methods for providing the same
ATE504288T1 (de) *	2003-09-26	2011-04-15	Alza Corp	Oros-push-stick für die kontrollierte abgabe von wirkstoffen
CA2540050A1 (en) *	2003-09-26	2005-04-07	Nishit B. Modi	Osmotic dosage forms for controlled delivery of alprazolam
CA2540056C (en) *	2003-09-26	2015-03-24	Alza Corporation	Controlled release formulations of opioid and nonopioid analgesics
US7407973B2 (en) *	2003-10-24	2008-08-05	Intermune, Inc.	Use of pirfenidone in therapeutic regimens
US20050118246A1 (en) *	2003-10-31	2005-06-02	Wong Patrick S.	Dosage forms and layered deposition processes for fabricating dosage forms
US7299082B2 (en)	2003-10-31	2007-11-20	Abbott Diabetes Care, Inc.	Method of calibrating an analyte-measurement device, and associated methods, devices and systems
EP1677758A1 (de) *	2003-10-31	2006-07-12	ALZA Corporation	Zusammensetzungen und dosierformen für verbesserte absorption von 3-amino-n-butyl-phosphinsäure
USD902408S1 (en)	2003-11-05	2020-11-17	Abbott Diabetes Care Inc.	Analyte sensor control unit
US20050250737A1 (en) *	2003-11-12	2005-11-10	Allergan, Inc.	Therapeutic ophthalmic compositions containing retinal friendly excipients and related methods
US20070224278A1 (en) *	2003-11-12	2007-09-27	Lyons Robert T	Low immunogenicity corticosteroid compositions
US20060141049A1 (en) *	2003-11-12	2006-06-29	Allergan, Inc.	Triamcinolone compositions for intravitreal administration to treat ocular conditions
US20050101582A1 (en) *	2003-11-12	2005-05-12	Allergan, Inc.	Compositions and methods for treating a posterior segment of an eye
US9247900B2 (en)	2004-07-13	2016-02-02	Dexcom, Inc.	Analyte sensor
DE10355461A1 (de)	2003-11-27	2005-06-23	Bayer Healthcare Ag	Verfahren zur Herstellung einer festen, oral applizierbaren pharmazeutischen Zusammensetzung
CN1886427B (zh) *	2003-11-28	2012-05-23	伊士曼化工公司	纤维素共聚体和氧化方法
US11633133B2 (en)	2003-12-05	2023-04-25	Dexcom, Inc.	Dual electrode system for a continuous analyte sensor
EP1711790B1 (de)	2003-12-05	2010-09-08	DexCom, Inc.	Kalibrationsmethoden für einen kontinuierlich arbeitenden analytsensor
US8423114B2 (en)	2006-10-04	2013-04-16	Dexcom, Inc.	Dual electrode system for a continuous analyte sensor
US7769461B2 (en) *	2003-12-19	2010-08-03	Boston Scientific Neuromodulation Corporation	Skull-mounted electrical stimulation system and method for treating patients
KR20060123493A (ko) *	2003-12-23	2006-12-01	알자 코포레이션	제어된 전달을 위한 약물 조성물의 용해도를 증가시키는방법 및 제형
EP1701706A2 (de) *	2003-12-29	2006-09-20	Alza Corporation	Neue arzneimittelzusammensetzungen und dosierformen
US20050175696A1 (en) *	2003-12-29	2005-08-11	David Edgren	Drug granule coatings that impart smear resistance during mechanical compression
JP2007517063A (ja) *	2003-12-29	2007-06-28	アルザ・コーポレーシヨン	トピラメートの新規な薬剤組成物および剤形
BRPI0506983A (pt)	2004-01-20	2007-07-03	Allergan Inc	composições para terapia localizada dos olhos, compreendendo preferencialmente acetonida de triancinolona e ácido hialurÈnico
US8808228B2 (en)	2004-02-26	2014-08-19	Dexcom, Inc.	Integrated medicament delivery device for use with continuous analyte sensor
US20050196447A1 (en) *	2004-03-05	2005-09-08	Huang Hai Y.	Polymeric compositions and dosage forms comprising the same
US20050196442A1 (en) *	2004-03-05	2005-09-08	Huang Hai Y.	Polymeric compositions and dosage forms comprising the same
US20050196448A1 (en) *	2004-03-05	2005-09-08	Hai Yong Huang	Polymeric compositions and dosage forms comprising the same
US20050196446A1 (en) *	2004-03-05	2005-09-08	Huang Hai Y.	Polymeric compositions and dosage forms comprising the same
US20050226929A1 (en) *	2004-04-12	2005-10-13	Jianbo Xie	Controlled release opioid analgesic formulation
US20050244472A1 (en) *	2004-04-30	2005-11-03	Allergan, Inc.	Intraocular drug delivery systems containing excipients with reduced toxicity and related methods
US8591885B2 (en) *	2004-04-30	2013-11-26	Allergan, Inc.	Carbonic anhydrase inhibitor sustained release intraocular drug delivery systems
US20050244469A1 (en) *	2004-04-30	2005-11-03	Allergan, Inc.	Extended therapeutic effect ocular implant treatments
US8722097B2 (en)	2004-04-30	2014-05-13	Allergan, Inc.	Oil-in-water method for making polymeric implants containing a hypotensive lipid
US20050244466A1 (en) *	2004-04-30	2005-11-03	Allergan, Inc.	Photodynamic therapy in conjunction with intraocular implants
WO2005107708A1 (en)	2004-04-30	2005-11-17	Allergan, Inc.	Biodegradable intravitreal tyrosine kinase inhibitors implants
US20060182783A1 (en) *	2004-04-30	2006-08-17	Allergan, Inc.	Sustained release intraocular drug delivery systems
US20050244478A1 (en) *	2004-04-30	2005-11-03	Allergan, Inc.	Anti-excititoxic sustained release intraocular implants and related methods
US20050244458A1 (en) *	2004-04-30	2005-11-03	Allergan, Inc.	Sustained release intraocular implants and methods for treating ocular neuropathies
US20050244471A1 (en) *	2004-04-30	2005-11-03	Allergan, Inc.	Estradiol derivative and estratopone containing sustained release intraocular implants and related methods
US20050244465A1 (en) *	2004-04-30	2005-11-03	Allergan, Inc.	Drug delivery systems and methods for treatment of an eye
US7993634B2 (en)	2004-04-30	2011-08-09	Allergan, Inc.	Oil-in-oil emulsified polymeric implants containing a hypotensive lipid and related methods
US9498457B2 (en)	2004-04-30	2016-11-22	Allergan, Inc.	Hypotensive prostamide-containing biodegradable intraocular implants and related implants
US8425929B2 (en)	2004-04-30	2013-04-23	Allergan, Inc.	Sustained release intraocular implants and methods for preventing retinal dysfunction
US8147865B2 (en)	2004-04-30	2012-04-03	Allergan, Inc.	Steroid-containing sustained release intraocular implants and related methods
US20050244461A1 (en) *	2004-04-30	2005-11-03	Allergan, Inc.	Controlled release drug delivery systems and methods for treatment of an eye
US20050244463A1 (en) *	2004-04-30	2005-11-03	Allergan, Inc.	Sustained release intraocular implants and methods for treating ocular vasculopathies
US20070059336A1 (en) *	2004-04-30	2007-03-15	Allergan, Inc.	Anti-angiogenic sustained release intraocular implants and related methods
US8529927B2 (en) *	2004-04-30	2013-09-10	Allergan, Inc.	Alpha-2 agonist polymeric drug delivery systems
US8119154B2 (en) *	2004-04-30	2012-02-21	Allergan, Inc.	Sustained release intraocular implants and related methods
US20060182781A1 (en) *	2004-04-30	2006-08-17	Allergan, Inc.	Methods for treating ocular conditions with cyclic lipid contraining microparticles
US7799336B2 (en) *	2004-04-30	2010-09-21	Allergan, Inc.	Hypotensive lipid-containing biodegradable intraocular implants and related methods
US7771742B2 (en)	2004-04-30	2010-08-10	Allergan, Inc.	Sustained release intraocular implants containing tyrosine kinase inhibitors and related methods
US7589057B2 (en)	2004-04-30	2009-09-15	Allergan, Inc.	Oil-in-water method for making alpha-2 agonist polymeric drug delivery systems
US8673341B2 (en) *	2004-04-30	2014-03-18	Allergan, Inc.	Intraocular pressure reduction with intracameral bimatoprost implants
US20050244462A1 (en) *	2004-04-30	2005-11-03	Allergan, Inc.	Devices and methods for treating a mammalian eye
US20050244500A1 (en) *	2004-04-30	2005-11-03	Allergan, Inc.	Intravitreal implants in conjuction with photodynamic therapy to improve vision
DE102004023069A1 (de)	2004-05-11	2005-12-08	Bayer Healthcare Ag	Neue Darreichungsformen des PDE 5-Inhibitors Vardenafil
US20050267555A1 (en) *	2004-05-28	2005-12-01	Marnfeldt Goran N	Engagement tool for implantable medical devices
CA2572455C (en)	2004-06-04	2014-10-28	Therasense, Inc.	Diabetes care host-client architecture and data management system
WO2006007323A2 (en) *	2004-06-28	2006-01-19	Alza Corporation	Dosage forms for low solubility and/or low dissolution rate free acid pharmaceutical agents
US8394409B2 (en) *	2004-07-01	2013-03-12	Intellipharmaceutics Corp.	Controlled extended drug release technology
US20080027513A1 (en) *	2004-07-09	2008-01-31	Advanced Bionics Corporation	Systems And Methods For Using A Butterfly Coil To Communicate With Or Transfer Power To An Implantable Medical Device
EP2216026B1 (de) *	2004-07-12	2016-04-20	Allergan, Inc.	Ophthalmologische Zusammensetzungen und deren Verwendung zur Behandlung von Augenkrankheiten
US7905833B2 (en)	2004-07-13	2011-03-15	Dexcom, Inc.	Transcutaneous analyte sensor
US8565848B2 (en)	2004-07-13	2013-10-22	Dexcom, Inc.	Transcutaneous analyte sensor
US7783333B2 (en)	2004-07-13	2010-08-24	Dexcom, Inc.	Transcutaneous medical device with variable stiffness
US7857760B2 (en)	2004-07-13	2010-12-28	Dexcom, Inc.	Analyte sensor
WO2006127694A2 (en)	2004-07-13	2006-11-30	Dexcom, Inc.	Analyte sensor
US8452368B2 (en)	2004-07-13	2013-05-28	Dexcom, Inc.	Transcutaneous analyte sensor
US8452407B2 (en) *	2004-08-16	2013-05-28	Boston Scientific Neuromodulation Corporation	Methods for treating gastrointestinal disorders
US10624858B2 (en)	2004-08-23	2020-04-21	Intellipharmaceutics Corp	Controlled release composition using transition coating, and method of preparing same
ATE458489T1 (de) *	2004-08-30	2010-03-15	Seo Hong Yoo	Nervenschutzwirkung von aufgelöster udca bei einem fokalen ischämischen modell
US8252321B2 (en)	2004-09-13	2012-08-28	Chrono Therapeutics, Inc.	Biosynchronous transdermal drug delivery for longevity, anti-aging, fatigue management, obesity, weight loss, weight management, delivery of nutraceuticals, and the treatment of hyperglycemia, alzheimer's disease, sleep disorders, parkinson's disease, aids, epilepsy, attention deficit disorder, nicotine addiction, cancer, headache and pain control, asthma, angina, hypertension, depression, cold, flu and the like
US7780981B2 (en)	2004-09-13	2010-08-24	Chrono Therapeutics, Inc.	Biosynchronous transdermal drug delivery
US8541026B2 (en) *	2004-09-24	2013-09-24	Abbvie Inc.	Sustained release formulations of opioid and nonopioid analgesics
JP2008516977A (ja) *	2004-10-15	2008-05-22	セオホンユー	薬剤学的化合物の毒性を減少させるための方法及び組成物
DE602005025391D1 (de) *	2004-11-01	2011-01-27	Seo Hong Yoo	Verfahren und zusammensetzungen zur verringerung der neurodegeneration bei amyotrophischer lateralsklerose
US9358393B1 (en)	2004-11-09	2016-06-07	Andres M. Lozano	Stimulation methods and systems for treating an auditory dysfunction
AR053986A1 (es)	2004-12-03	2007-05-30	Osmotica Pharmaceutical Argent	Dispositivo osmotico que contiene amantadina y una sal osmotica
US7483746B2 (en) *	2004-12-06	2009-01-27	Boston Scientific Neuromodulation Corp.	Stimulation of the stomach in response to sensed parameters to treat obesity
US9327069B2 (en)	2004-12-21	2016-05-03	Boston Scientific Neuromodulation Corporation	Methods and systems for treating a medical condition by promoting neural remodeling within the brain
US9095713B2 (en) *	2004-12-21	2015-08-04	Allison M. Foster	Methods and systems for treating autism by decreasing neural activity within the brain
US20060161217A1 (en) *	2004-12-21	2006-07-20	Jaax Kristen N	Methods and systems for treating obesity
US20070038264A1 (en) *	2004-12-21	2007-02-15	Jaax Kristen N	Methods and systems for treating autism
US20060134175A1 (en) *	2004-12-22	2006-06-22	Stephen Bartels	Drug eluting pharmaceutical delivery system for treatment of ocular disease and method of use
US20060134176A1 (en) *	2004-12-22	2006-06-22	Bausch & Lomb Incorporated	Pharmaceutical delivery system and method of use
KR20070101865A (ko) *	2004-12-22	2007-10-17	알콘, 인코퍼레이티드	안과용 약물 전달 장치
US9352145B2 (en) *	2004-12-22	2016-05-31	Boston Scientific Neuromodulation Corporation	Methods and systems for treating a psychotic disorder
US20060134174A1 (en) *	2004-12-22	2006-06-22	Bausch & Lomb Incorporated	Pharmaceutical delivery system and method of use
US8515541B1 (en)	2004-12-22	2013-08-20	Boston Scientific Neuromodulation Corporation	Methods and systems for treating post-stroke disorders
US7883464B2 (en)	2005-09-30	2011-02-08	Abbott Diabetes Care Inc.	Integrated transmitter unit and sensor introducer mechanism and methods of use
US8571624B2 (en)	2004-12-29	2013-10-29	Abbott Diabetes Care Inc.	Method and apparatus for mounting a data transmission device in a communication system
US8613703B2 (en)	2007-05-31	2013-12-24	Abbott Diabetes Care Inc.	Insertion devices and methods
US7731657B2 (en) *	2005-08-30	2010-06-08	Abbott Diabetes Care Inc.	Analyte sensor introducer and methods of use
US9788771B2 (en)	2006-10-23	2017-10-17	Abbott Diabetes Care Inc.	Variable speed sensor insertion devices and methods of use
US8029441B2 (en)	2006-02-28	2011-10-04	Abbott Diabetes Care Inc.	Analyte sensor transmitter unit configuration for a data monitoring and management system
US9398882B2 (en)	2005-09-30	2016-07-26	Abbott Diabetes Care Inc.	Method and apparatus for providing analyte sensor and data processing device
US9572534B2 (en)	2010-06-29	2017-02-21	Abbott Diabetes Care Inc.	Devices, systems and methods for on-skin or on-body mounting of medical devices
US9259175B2 (en)	2006-10-23	2016-02-16	Abbott Diabetes Care, Inc.	Flexible patch for fluid delivery and monitoring body analytes
US9636450B2 (en)	2007-02-19	2017-05-02	Udo Hoss	Pump system modular components for delivering medication and analyte sensing at seperate insertion sites
US9743862B2 (en)	2011-03-31	2017-08-29	Abbott Diabetes Care Inc.	Systems and methods for transcutaneously implanting medical devices
US8333714B2 (en)	2006-09-10	2012-12-18	Abbott Diabetes Care Inc.	Method and system for providing an integrated analyte sensor insertion device and data processing unit
US10226207B2 (en)	2004-12-29	2019-03-12	Abbott Diabetes Care Inc.	Sensor inserter having introducer
US7697967B2 (en)	2005-12-28	2010-04-13	Abbott Diabetes Care Inc.	Method and apparatus for providing analyte sensor insertion
US20090105569A1 (en)	2006-04-28	2009-04-23	Abbott Diabetes Care, Inc.	Introducer Assembly and Methods of Use
US8545403B2 (en)	2005-12-28	2013-10-01	Abbott Diabetes Care Inc.	Medical device insertion
US8512243B2 (en)	2005-09-30	2013-08-20	Abbott Diabetes Care Inc.	Integrated introducer and transmitter assembly and methods of use
IL166114A0 (en) *	2005-01-03	2006-01-15	Calcident Active Ltd	Long-acting controlled-release pharmaceutical preparation for use in the oral cavity
DE602006003639D1 (de) *	2005-01-27	2008-12-24	Alza Corp	Orale osmotische darreichungsform mit membran mit hoher flussdichte
EP1685841A1 (de) *	2005-01-31	2006-08-02	Bayer Health Care Aktiengesellschaft	Prophylaxe und Behandlung von thrombolischen Erkrankungen
EP1853272A1 (de) *	2005-02-03	2007-11-14	Duramed Pharmaceuticals, Inc.	Zusammensetzungen aus unkonjugierten östrogenen und anwendungsverfahren dafür
CA2596933A1 (en) *	2005-02-03	2006-08-10	Duramed Pharmaceuticals, Inc.	Devices for delivering agents to a vaginal tract
EP1690540A1 (de) *	2005-02-15	2006-08-16	Neuro3D	Zusammensetzung enthaltend Ocaperidon
US20060185665A1 (en) *	2005-02-22	2006-08-24	Bachinski Thomas J	Sauna fireplace
US20060194724A1 (en) *	2005-02-25	2006-08-31	Whitehurst Todd K	Methods and systems for nerve regeneration
US20060204548A1 (en)	2005-03-01	2006-09-14	Allergan, Inc.	Microimplants for ocular administration
US7853321B2 (en) *	2005-03-14	2010-12-14	Boston Scientific Neuromodulation Corporation	Stimulation of a stimulation site within the neck or head
US8423155B1 (en)	2005-03-14	2013-04-16	Boston Scientific Neuromodulation Corporation	Methods and systems for facilitating stimulation of one or more stimulation sites
US7702385B2 (en) *	2005-11-16	2010-04-20	Boston Scientific Neuromodulation Corporation	Electrode contact configurations for an implantable stimulator
US7848803B1 (en)	2005-03-14	2010-12-07	Boston Scientific Neuromodulation Corporation	Methods and systems for facilitating stimulation of one or more stimulation sites
US20060233882A1 (en) *	2005-04-15	2006-10-19	Sowden Harry S	Osmotic dosage form
CA2605180A1 (en) *	2005-04-19	2006-10-26	Alza Corporation	Controlled delivery dosage form of tramadol and gabapentin
US8112240B2 (en)	2005-04-29	2012-02-07	Abbott Diabetes Care Inc.	Method and apparatus for providing leak detection in data monitoring and management systems
US7931909B2 (en) *	2005-05-10	2011-04-26	Allergan, Inc.	Ocular therapy using alpha-2 adrenergic receptor compounds having enhanced anterior clearance rates
CN101291652A (zh) *	2005-06-29	2008-10-22	阿尔扎公司	对渗透剂型提供降低的干燥时间的半渗透性组合物
DE102005031577A1 (de) *	2005-07-06	2007-01-11	Bayer Healthcare Ag	Pharmazeutische Darreichungsformen enthaltend eine Wirkstoffkombination von Nifedipin und/oder Nisoldipin und einem Angiotensin-II Antagonisten
GB2442396B (en) *	2005-07-22	2011-05-11	Univ Utah Res Found	Osmotically driven dispense pump and related components for use in high pressure applications
CN101267779A (zh)	2005-07-27	2008-09-17	福罗里达大学研究基金会有限公司	使用热休克治疗眼睛疾病
EP1912622A2 (de) *	2005-08-04	2008-04-23	Alza Corporation	Osmotische dosierungsformen mit halbdurchlässigen membranen mit polymer-mischungen mit verbesserten eigenschaften
US8778395B2 (en)	2005-08-11	2014-07-15	Andrx Labs, Llc	Diltiazem controlled release formulation and method of manufacture
US20070048347A1 (en)	2005-08-26	2007-03-01	Laura Bardach	Intra-oral device for treating obesity
EP1921980A4 (de)	2005-08-31	2010-03-10	Univ Virginia	Verbesserung der genauigkeit von kontinuierlichen glucosesensoren
US20070212397A1 (en) *	2005-09-15	2007-09-13	Roth Daniel B	Pharmaceutical delivery device and method for providing ocular treatment
US7684858B2 (en) *	2005-09-21	2010-03-23	Boston Scientific Neuromodulation Corporation	Methods and systems for placing an implanted stimulator for stimulating tissue
DE102005045518A1 (de) *	2005-09-23	2007-03-29	Bayer Healthcare Ag	2-Aminoethoxyessigsäure-Derivate und ihre Verwendung
CN101316602B (zh)	2005-09-27	2015-06-03	组织技术公司	羊膜制品和纯化的组合物及其使用方法
US8187639B2 (en) *	2005-09-27	2012-05-29	Tissue Tech, Inc.	Amniotic membrane preparations and purified compositions and anti-angiogenesis treatment
US8880138B2 (en)	2005-09-30	2014-11-04	Abbott Diabetes Care Inc.	Device for channeling fluid and methods of use
US9521968B2 (en)	2005-09-30	2016-12-20	Abbott Diabetes Care Inc.	Analyte sensor retention mechanism and methods of use
DE102005047561A1 (de)	2005-10-04	2007-04-05	Bayer Healthcare Ag	Feste, oral applizierbare pharmazeutische Darreichungsformen mit schneller Wirkstofffreisetzung
DE102005047558A1 (de) *	2005-10-04	2008-02-07	Bayer Healthcare Ag	Kombinationstherapie substituierter Oxazolidinone zur Prophylaxe und Behandlung von cerebralen Durchblutungsstörungen
MY145616A (en)	2005-10-04	2012-03-15	Bayer Schering Pharma Ag	Novel polymorphous form and the amorphous form of 5-chloro-n-({(5s)-2-oxo-3-[4-(3-oxo-4-morpholinyl)-phenyl]-1,3-oxazolidine-5-yl}-methyl)-2-thiophene carboxamide
WO2007044234A1 (en) *	2005-10-07	2007-04-19	Alza Corporation	Osmotic dosage form with controlled release and fast release aspects
PL116330U1 (en) *	2005-10-31	2007-04-02	Alza Corp	Method for the reduction of alcohol provoked rapid increase in the released dose of the orally administered opioide with prolonged liberation
US7766829B2 (en)	2005-11-04	2010-08-03	Abbott Diabetes Care Inc.	Method and system for providing basal profile modification in analyte monitoring and management systems
CA2629775A1 (en) *	2005-11-14	2007-05-24	Enterprise Partners Venture Capital	Stem cell factor therapy for tissue injury
MX336930B (es)	2005-11-28	2016-02-05	Marinus Pharmaceuticals	Formulaciones de ganaxolona y metodos para la manufactura y el uso de las mismas.
WO2007064752A2 (en)	2005-11-29	2007-06-07	Smithkline Beecham Corporation	Treatment of ocular neovascular disorders such as macular degeneration, angiod streaks, uveitis and macular edema
US7729758B2 (en) *	2005-11-30	2010-06-01	Boston Scientific Neuromodulation Corporation	Magnetically coupled microstimulators
US10064828B1 (en)	2005-12-23	2018-09-04	Intellipharmaceutics Corp.	Pulsed extended-pulsed and extended-pulsed pulsed drug delivery systems
US11298058B2 (en)	2005-12-28	2022-04-12	Abbott Diabetes Care Inc.	Method and apparatus for providing analyte sensor insertion
US7610100B2 (en) *	2005-12-30	2009-10-27	Boston Scientific Neuromodulation Corporation	Methods and systems for treating osteoarthritis
US7835803B1 (en)	2006-01-17	2010-11-16	Boston Scientific Neuromodulation Corporation	Lead assemblies with one or more switching networks
US20090317355A1 (en) *	2006-01-21	2009-12-24	Abbott Gmbh & Co. Kg,	Abuse resistant melt extruded formulation having reduced alcohol interaction
US20090022798A1 (en) *	2007-07-20	2009-01-22	Abbott Gmbh & Co. Kg	Formulations of nonopioid and confined opioid analgesics
US20100172989A1 (en) *	2006-01-21	2010-07-08	Abbott Laboratories	Abuse resistant melt extruded formulation having reduced alcohol interaction
US7736310B2 (en)	2006-01-30	2010-06-15	Abbott Diabetes Care Inc.	On-body medical device securement
US20070178138A1 (en) *	2006-02-01	2007-08-02	Allergan, Inc.	Biodegradable non-opthalmic implants and related methods
US20070196487A1 (en) *	2006-02-16	2007-08-23	Geerke Johan H	Method and apparatus for drilling orifices in osmotic tablets incorporating near-infrared spectroscopy
US7885698B2 (en)	2006-02-28	2011-02-08	Abbott Diabetes Care Inc.	Method and system for providing continuous calibration of implantable analyte sensors
US7826879B2 (en)	2006-02-28	2010-11-02	Abbott Diabetes Care Inc.	Analyte sensors and methods of use
US8309104B2 (en) *	2006-03-02	2012-11-13	Watson Pharmaceuticals, Inc.	Oral controlled release formulation for sedative and hypnotic agents
US8175710B2 (en) *	2006-03-14	2012-05-08	Boston Scientific Neuromodulation Corporation	Stimulator system with electrode array and the method of making the same
US7777641B2 (en) *	2006-03-29	2010-08-17	Advanced Bionics, Llc	Systems and methods of facilitating communication between a first and second device
US8478557B2 (en)	2009-07-31	2013-07-02	Abbott Diabetes Care Inc.	Method and apparatus for providing analyte monitoring system calibration accuracy
US7801582B2 (en)	2006-03-31	2010-09-21	Abbott Diabetes Care Inc.	Analyte monitoring and management system and methods therefor
US9326709B2 (en)	2010-03-10	2016-05-03	Abbott Diabetes Care Inc.	Systems, devices and methods for managing glucose levels
US8140312B2 (en)	2007-05-14	2012-03-20	Abbott Diabetes Care Inc.	Method and system for determining analyte levels
US8226891B2 (en)	2006-03-31	2012-07-24	Abbott Diabetes Care Inc.	Analyte monitoring devices and methods therefor
US8224415B2 (en)	2009-01-29	2012-07-17	Abbott Diabetes Care Inc.	Method and device for providing offset model based calibration for analyte sensor
US8473022B2 (en)	2008-01-31	2013-06-25	Abbott Diabetes Care Inc.	Analyte sensor with time lag compensation
US7620438B2 (en)	2006-03-31	2009-11-17	Abbott Diabetes Care Inc.	Method and system for powering an electronic device
US7630748B2 (en)	2006-10-25	2009-12-08	Abbott Diabetes Care Inc.	Method and system for providing analyte monitoring
US8346335B2 (en)	2008-03-28	2013-01-01	Abbott Diabetes Care Inc.	Analyte sensor calibration management
US8583205B2 (en)	2008-03-28	2013-11-12	Abbott Diabetes Care Inc.	Analyte sensor calibration management
US9675290B2 (en)	2012-10-30	2017-06-13	Abbott Diabetes Care Inc.	Sensitivity calibration of in vivo sensors used to measure analyte concentration
US9392969B2 (en)	2008-08-31	2016-07-19	Abbott Diabetes Care Inc.	Closed loop control and signal attenuation detection
US8219173B2 (en)	2008-09-30	2012-07-10	Abbott Diabetes Care Inc.	Optimizing analyte sensor calibration
US7618369B2 (en)	2006-10-02	2009-11-17	Abbott Diabetes Care Inc.	Method and system for dynamically updating calibration parameters for an analyte sensor
US7653425B2 (en)	2006-08-09	2010-01-26	Abbott Diabetes Care Inc.	Method and system for providing calibration of an analyte sensor in an analyte monitoring system
US8374668B1 (en)	2007-10-23	2013-02-12	Abbott Diabetes Care Inc.	Analyte sensor with lag compensation
US9339217B2 (en)	2011-11-25	2016-05-17	Abbott Diabetes Care Inc.	Analyte monitoring system and methods of use
CN104825397A (zh) *	2006-04-03	2015-08-12	伊萨·奥迪迪	含有机溶胶涂层的受控释放递送物件
WO2007121188A2 (en) *	2006-04-10	2007-10-25	Knopp Neurosciences, Inc.	Compositions and methods of using r(+) pramipexole
US8518926B2 (en) *	2006-04-10	2013-08-27	Knopp Neurosciences, Inc.	Compositions and methods of using (R)-pramipexole
US8747897B2 (en)	2006-04-27	2014-06-10	Supernus Pharmaceuticals, Inc.	Osmotic drug delivery system
US9011930B2 (en) *	2006-05-01	2015-04-21	Zycal Bioceuticals Healthcare Company, Inc.	Nutritional supplement and use thereof
US20070260203A1 (en) *	2006-05-04	2007-11-08	Allergan, Inc.	Vasoactive agent intraocular implant
US10960077B2 (en)	2006-05-12	2021-03-30	Intellipharmaceutics Corp.	Abuse and alcohol resistant drug composition
CN102160865A (zh) *	2006-05-16	2011-08-24	诺普神经科学股份有限公司	R(+)和s(-)普拉克索的组合物以及使用该组合物的方法
US20080071157A1 (en)	2006-06-07	2008-03-20	Abbott Diabetes Care, Inc.	Analyte monitoring system and method
DK2526932T3 (en) *	2006-06-19	2017-07-17	Alpharma Pharmaceuticals Llc	Pharmaceutical composition
US20070298073A1 (en) *	2006-06-23	2007-12-27	Allergan, Inc.	Steroid-containing sustained release intraocular implants and related methods
US8802128B2 (en)	2006-06-23	2014-08-12	Allergan, Inc.	Steroid-containing sustained release intraocular implants and related methods
US8504163B1 (en)	2006-06-30	2013-08-06	Boston Scientific Neuromodulation Corporation	Cranially mounted stimulation systems and methods
US8401654B1 (en)	2006-06-30	2013-03-19	Boston Scientific Neuromodulation Corporation	Methods and systems for treating one or more effects of deafferentation
CN101528830A (zh)	2006-07-10	2009-09-09	麦德医像公司	超弹性环氧水凝胶
US20080090897A1 (en)	2006-08-11	2008-04-17	The Johns Hopkins University	Compositions and methods for neuroprotectin
CA2666814A1 (en) *	2006-08-21	2008-05-29	United Therapeutics Corporation	Combination therapy for treatment of viral infections
PT2530083T (pt)	2006-09-22	2016-08-01	Pharmacyclics Llc	Inibidores de tirosina cinase de bruton
US7445528B1 (en)	2006-09-29	2008-11-04	Boston Scientific Neuromodulation Corporation	Connector assemblies
EP2106238A4 (de)	2006-10-26	2011-03-09	Abbott Diabetes Care Inc	Verfahren, system und computerprogrammprodukt zur echtzeit-erkennung eines empfindlichkeitsabfalls in analytsensoren
US7347746B1 (en)	2006-10-27	2008-03-25	Boston Scientific Neuromodulation Corporation	Receptacle connector assembly
DE102006051625A1 (de) *	2006-11-02	2008-05-08	Bayer Materialscience Ag	Kombinationstherapie substituierter Oxazolidinone
US8586556B2 (en)	2006-11-03	2013-11-19	Allergan, Inc.	Methods, compositions and drug delivery systems for intraocular delivery of siRNA molecules
CA2670990A1 (en)	2006-12-01	2008-06-12	Allergan, Inc.	Method for determining optimum intraocular locations for drug delivery systems
US8969415B2 (en)	2006-12-01	2015-03-03	Allergan, Inc.	Intraocular drug delivery systems
US8524695B2 (en) *	2006-12-14	2013-09-03	Knopp Neurosciences, Inc.	Modified release formulations of (6R)-4,5,6,7-tetrahydro-N6-propyl-2,6-benzothiazole-diamine and methods of using the same
US8846073B2 (en) *	2006-12-19	2014-09-30	Allergan, Inc.	Low temperature processes for making cyclic lipid implants for intraocular use
US20090011018A1 (en) *	2006-12-28	2009-01-08	Astellas Pharma Inc.,	Sustained release formulation for tacrolimus
WO2008089260A2 (en) *	2007-01-16	2008-07-24	Victory Pharma, Inc.	Combined administration of benzonatate and guaifenesin
US8524749B2 (en) *	2007-02-09	2013-09-03	Alza Corporation	Controlled release compositions of tizanidine
US20080199894A1 (en)	2007-02-15	2008-08-21	Abbott Diabetes Care, Inc.	Device and method for automatic data acquisition and/or detection
US8121857B2 (en)	2007-02-15	2012-02-21	Abbott Diabetes Care Inc.	Device and method for automatic data acquisition and/or detection
US8930203B2 (en)	2007-02-18	2015-01-06	Abbott Diabetes Care Inc.	Multi-function analyte test device and methods therefor
US8732188B2 (en)	2007-02-18	2014-05-20	Abbott Diabetes Care Inc.	Method and system for providing contextual based medication dosage determination
US8123686B2 (en)	2007-03-01	2012-02-28	Abbott Diabetes Care Inc.	Method and apparatus for providing rolling data in communication systems
US8519148B2 (en)	2007-03-14	2013-08-27	Knopp Neurosciences, Inc.	Synthesis of chirally purified substituted benzothiazole diamines
US8642067B2 (en)	2007-04-02	2014-02-04	Allergen, Inc.	Methods and compositions for intraocular administration to treat ocular conditions
WO2008128210A1 (en)	2007-04-14	2008-10-23	Abbott Diabetes Care, Inc.	Method and apparatus for providing data processing and control in medical communication system
US9204827B2 (en)	2007-04-14	2015-12-08	Abbott Diabetes Care Inc.	Method and apparatus for providing data processing and control in medical communication system
EP3741291A1 (de)	2007-04-14	2020-11-25	Abbott Diabetes Care, Inc.	Verfahren und vorrichtung zur bereitstellung von datenverarbeitung und -kontrolle in einem medizinischen kommunikationssystemen
US9008743B2 (en)	2007-04-14	2015-04-14	Abbott Diabetes Care Inc.	Method and apparatus for providing data processing and control in medical communication system
ES2784736T3 (es)	2007-04-14	2020-09-30	Abbott Diabetes Care Inc	Procedimiento y aparato para proporcionar el procesamiento y control de datos en un sistema de comunicación médica
EP2146622B1 (de)	2007-04-14	2016-05-11	Abbott Diabetes Care Inc.	Verfahren und vorrichtung für dynamische mehrstufige signalverstärkung bei einer medizinischen vorrichtung
US7911053B2 (en) *	2007-04-19	2011-03-22	Marvell World Trade Ltd.	Semiconductor packaging with internal wiring bus
US7928850B2 (en)	2007-05-08	2011-04-19	Abbott Diabetes Care Inc.	Analyte monitoring system and methods
US8461985B2 (en)	2007-05-08	2013-06-11	Abbott Diabetes Care Inc.	Analyte monitoring system and methods
US8665091B2 (en)	2007-05-08	2014-03-04	Abbott Diabetes Care Inc.	Method and device for determining elapsed sensor life
US8456301B2 (en)	2007-05-08	2013-06-04	Abbott Diabetes Care Inc.	Analyte monitoring system and methods
US7996158B2 (en)	2007-05-14	2011-08-09	Abbott Diabetes Care Inc.	Method and apparatus for providing data processing and control in a medical communication system
US8103471B2 (en)	2007-05-14	2012-01-24	Abbott Diabetes Care Inc.	Method and apparatus for providing data processing and control in a medical communication system
US8239166B2 (en)	2007-05-14	2012-08-07	Abbott Diabetes Care Inc.	Method and apparatus for providing data processing and control in a medical communication system
US8600681B2 (en)	2007-05-14	2013-12-03	Abbott Diabetes Care Inc.	Method and apparatus for providing data processing and control in a medical communication system
US8260558B2 (en)	2007-05-14	2012-09-04	Abbott Diabetes Care Inc.	Method and apparatus for providing data processing and control in a medical communication system
US8444560B2 (en)	2007-05-14	2013-05-21	Abbott Diabetes Care Inc.	Method and apparatus for providing data processing and control in a medical communication system
US9125548B2 (en)	2007-05-14	2015-09-08	Abbott Diabetes Care Inc.	Method and apparatus for providing data processing and control in a medical communication system
US10002233B2 (en)	2007-05-14	2018-06-19	Abbott Diabetes Care Inc.	Method and apparatus for providing data processing and control in a medical communication system
US8560038B2 (en)	2007-05-14	2013-10-15	Abbott Diabetes Care Inc.	Method and apparatus for providing data processing and control in a medical communication system
US20200037874A1 (en)	2007-05-18	2020-02-06	Dexcom, Inc.	Analyte sensors having a signal-to-noise ratio substantially unaffected by non-constant noise
CA2688184A1 (en)	2007-06-08	2008-12-18	Dexcom, Inc.	Integrated medicament delivery device for use with continuous analyte sensor
CN103251414B (zh)	2007-06-21	2017-05-24	雅培糖尿病护理公司	用于分析物水平的检测的设备
US8597188B2 (en)	2007-06-21	2013-12-03	Abbott Diabetes Care Inc.	Health management devices and methods
US8160900B2 (en)	2007-06-29	2012-04-17	Abbott Diabetes Care Inc.	Analyte monitoring and management device and method to analyze the frequency of user interaction with the device
US8834366B2 (en)	2007-07-31	2014-09-16	Abbott Diabetes Care Inc.	Method and apparatus for providing analyte sensor calibration
US7768386B2 (en)	2007-07-31	2010-08-03	Abbott Diabetes Care Inc.	Method and apparatus for providing data processing and control in a medical communication system
WO2009032286A2 (en) *	2007-09-06	2009-03-12	Nektar Therapeutics Al, Corporation	Oligomer-calcium channel blocker conjugates
JP5411141B2 (ja)	2007-09-10	2014-02-12	カルシメディカ，インク．	細胞内カルシウムを調節する化合物
US20090088681A1 (en) *	2007-10-02	2009-04-02	Mcintyre Jon T	Device and method for the treatment of intra-abdominal disease
EP4468309A3 (de)	2007-10-09	2024-12-11	DexCom, Inc.	Integriertes insulinabgabesystem mit kontinuierlichem glucosesensor
TWI498136B (zh) *	2007-10-09	2015-09-01	Alcon Res Ltd	用於遞送速率及溫度相依性物質至眼睛的注射器及其製備方法
TWI451862B (zh) *	2007-10-09	2014-09-11	Alcon Res Ltd	用於眼睛注射的熱係數驅動藥丸尺寸
US8409093B2 (en)	2007-10-23	2013-04-02	Abbott Diabetes Care Inc.	Assessing measures of glycemic variability
US8377031B2 (en)	2007-10-23	2013-02-19	Abbott Diabetes Care Inc.	Closed loop control system with safety parameters and methods
US8216138B1 (en)	2007-10-23	2012-07-10	Abbott Diabetes Care Inc.	Correlation of alternative site blood and interstitial fluid glucose concentrations to venous glucose concentration
WO2009073734A2 (en) *	2007-12-03	2009-06-11	Medipacs, Inc.	Fluid metering device
EP2219622A1 (de)	2007-12-06	2010-08-25	Durect Corporation	Verfahren zur behandlung von schmerzen, arthritischen zuständen oder entzündung im zusammenhang mit einer chronischen erkrankung
US8623418B2 (en)	2007-12-17	2014-01-07	Alpharma Pharmaceuticals Llc	Pharmaceutical composition
US20100151014A1 (en) *	2008-12-16	2010-06-17	Alpharma Pharmaceuticals, Llc	Pharmaceutical composition
US20090164239A1 (en)	2007-12-19	2009-06-25	Abbott Diabetes Care, Inc.	Dynamic Display Of Glucose Information
US9226907B2 (en)	2008-02-01	2016-01-05	Abbvie Inc.	Extended release hydrocodone acetaminophen and related methods and uses thereof
CA2715584A1 (en) *	2008-02-15	2009-10-08	Sun Pharma Advanced Research Company Ltd.	Oral controlled release tablet
CA2721214A1 (en)	2008-04-10	2009-10-15	Abbott Diabetes Care Inc.	Method and system for sterilizing an analyte sensor
US7826382B2 (en)	2008-05-30	2010-11-02	Abbott Diabetes Care Inc.	Close proximity communication device and methods
US8591410B2 (en)	2008-05-30	2013-11-26	Abbott Diabetes Care Inc.	Method and apparatus for providing glycemic control
US8924159B2 (en)	2008-05-30	2014-12-30	Abbott Diabetes Care Inc.	Method and apparatus for providing glycemic control
US8876755B2 (en)	2008-07-14	2014-11-04	Abbott Diabetes Care Inc.	Closed loop control system interface and methods
EP2334185A4 (de) *	2008-08-19	2011-09-21	Knopp Neurosciences Inc	Zusammensetzungen und verfahren zur verwendung von (r)-pramipexol
US7981925B2 (en)	2008-08-27	2011-07-19	Calcimedica, Inc.	Compounds that modulate intracellular calcium
US8734422B2 (en)	2008-08-31	2014-05-27	Abbott Diabetes Care Inc.	Closed loop control with improved alarm functions
US8622988B2 (en)	2008-08-31	2014-01-07	Abbott Diabetes Care Inc.	Variable rate closed loop control and methods
US9943644B2 (en)	2008-08-31	2018-04-17	Abbott Diabetes Care Inc.	Closed loop control with reference measurement and methods thereof
US20100057040A1 (en)	2008-08-31	2010-03-04	Abbott Diabetes Care, Inc.	Robust Closed Loop Control And Methods
US8986208B2 (en)	2008-09-30	2015-03-24	Abbott Diabetes Care Inc.	Analyte sensor sensitivity attenuation mitigation
EP2341924A4 (de)	2008-10-02	2013-01-23	David Gladstone Inst	Verfahren zur behandlung von hepatitis-c-virusinfektionen
US20100104654A1 (en) *	2008-10-27	2010-04-29	Allergan, Inc.	Prostaglandin and prostamide drug delivery systems and intraocular therapeutic uses thereof
US20100260844A1 (en)	2008-11-03	2010-10-14	Scicinski Jan J	Oral pharmaceutical dosage forms
US9326707B2 (en)	2008-11-10	2016-05-03	Abbott Diabetes Care Inc.	Alarm characterization for analyte monitoring devices and systems
US9095506B2 (en)	2008-11-17	2015-08-04	Allergan, Inc.	Biodegradable alpha-2 agonist polymeric implants and therapeutic uses thereof
DE102008059206A1 (de)	2008-11-27	2010-06-10	Bayer Schering Pharma Aktiengesellschaft	Pharmazeutische Darreichungsform enthaltend Nifedipin oder Nisoldipin und einen Angiotensin-II Antagonisten und/oder ein Diuretikum
US8623395B2 (en)	2010-01-29	2014-01-07	Forsight Vision4, Inc.	Implantable therapeutic device
CN104887389B (zh)	2009-01-29	2017-06-23	弗赛特影像4股份有限公司	后段给药
US8103456B2 (en)	2009-01-29	2012-01-24	Abbott Diabetes Care Inc.	Method and device for early signal attenuation detection using blood glucose measurements
US9402544B2 (en)	2009-02-03	2016-08-02	Abbott Diabetes Care Inc.	Analyte sensor and apparatus for insertion of the sensor
US20100204325A1 (en)	2009-02-11	2010-08-12	Allergan, Inc.	Valproic acid drug delivery systems and intraocular therapeutic uses thereof
CN102448458B (zh)	2009-03-18	2015-07-22	小利兰·斯坦福大学理事会	治疗黄病毒科病毒感染的方法和组合物
WO2010121084A1 (en)	2009-04-15	2010-10-21	Abbott Diabetes Care Inc.	Analyte monitoring system having an alert
ES2559029T3 (es)	2009-04-24	2016-02-10	Tissue Tech, Inc.	Composiciones que contienen al complejo HC.HA y metodos de uso de las mismas
US9226701B2 (en)	2009-04-28	2016-01-05	Abbott Diabetes Care Inc.	Error detection in critical repeating data in a wireless sensor system
WO2010127051A1 (en)	2009-04-29	2010-11-04	Abbott Diabetes Care Inc.	Method and system for providing real time analyte sensor calibration with retrospective backfill
US8368556B2 (en)	2009-04-29	2013-02-05	Abbott Diabetes Care Inc.	Method and system for providing data communication in continuous glucose monitoring and management system
US20100278897A1 (en) *	2009-05-01	2010-11-04	Allergan, Inc.	Intraocular bioactive agent delivery system with molecular partitioning system
US8632511B2 (en) *	2009-05-06	2014-01-21	Alcon Research, Ltd.	Multiple thermal sensors in a multiple processor environment for temperature control in a drug delivery device
US8597274B2 (en)	2009-05-22	2013-12-03	Abbott Diabetes Care Inc.	Usability features for integrated insulin delivery system
US9184490B2 (en)	2009-05-29	2015-11-10	Abbott Diabetes Care Inc.	Medical device antenna systems having external antenna configurations
WO2010139111A1 (en)	2009-06-02	2010-12-09	Dow Global Technologies Inc.	Sustained release dosage form
IN2012DN00352A (de)	2009-06-16	2015-08-21	Bikam Pharmaceuticals Inc
AU2010262970A1 (en) *	2009-06-19	2012-01-12	Knopp Neurosciences, Inc.	Compositions and methods for treating amyotrophic lateral sclerosis
US8613892B2 (en)	2009-06-30	2013-12-24	Abbott Diabetes Care Inc.	Analyte meter with a moveable head and methods of using the same
ES2776474T3 (es)	2009-07-23	2020-07-30	Abbott Diabetes Care Inc	Sistema de medición continua de analitos
CN102573813B (zh) *	2009-08-18	2013-11-06	国立大学法人东北大学	持续药物传递系统
EP3001194B1 (de)	2009-08-31	2019-04-17	Abbott Diabetes Care, Inc.	Medizinische vorrichtungen und verfahren
US8514086B2 (en)	2009-08-31	2013-08-20	Abbott Diabetes Care Inc.	Displays for a medical device
EP2473099A4 (de)	2009-08-31	2015-01-14	Abbott Diabetes Care Inc	Analytüberwachungssystem und -verfahren zur leistungs- und rauschverwaltung
EP2473098A4 (de)	2009-08-31	2014-04-09	Abbott Diabetes Care Inc	Analytsignalverarbeitungsvorrichtung und -verfahren
WO2011032011A1 (en)	2009-09-10	2011-03-17	Medipacs, Inc.	Low profile actuator and improved method of caregiver controlled administration of therapeutics
DE102009042855A1 (de) *	2009-09-24	2011-03-31	Pfenning Elektroanlagen Gmbh	Portalhubwagen zum Einsatz in Containerterminals und für allgemeine Transportaufgaben
WO2011041469A1 (en)	2009-09-29	2011-04-07	Abbott Diabetes Care Inc.	Method and apparatus for providing notification function in analyte monitoring systems
WO2011041531A1 (en)	2009-09-30	2011-04-07	Abbott Diabetes Care Inc.	Interconnect for on-body analyte monitoring device
WO2011039648A1 (en)	2009-09-30	2011-04-07	Glaxo Wellcome Manufacturing Pte Ltd.	Methods of administration and treatment
US7741330B1 (en)	2009-10-12	2010-06-22	Pharmacyclics, Inc.	Pyrazolo-pyrimidine inhibitors of Bruton's tyrosine kinase
WO2011053881A1 (en)	2009-10-30	2011-05-05	Abbott Diabetes Care Inc.	Method and apparatus for detecting false hypoglycemic conditions
US20110124736A1 (en)	2009-11-09	2011-05-26	Allergan, Inc.	Compositions and methods for stimulating hair growth
US20120245505A1 (en)	2009-12-16	2012-09-27	Robinson Michael R	Intracameral devices for sustained delivery
US8177747B2 (en) *	2009-12-22	2012-05-15	Alcon Research, Ltd.	Method and apparatus for drug delivery
JP2013515741A (ja) *	2009-12-23	2013-05-09	サイヴィーダユーエス，インコーポレイテッド	持続放出性送達デバイス
US20110172637A1 (en) *	2010-01-08	2011-07-14	Ratio, Inc.	Drug delivery device including tissue support structure
US20110172609A1 (en) *	2010-01-08	2011-07-14	Ratio, Inc.	Microneedle component assembly for drug delivery device
US20110172645A1 (en) *	2010-01-08	2011-07-14	Ratio, Inc.	Wearable drug delivery device including integrated pumping and activation elements
US20110172639A1 (en) *	2010-01-08	2011-07-14	Ratio, Inc.	Device and method for delivery of microneedle to desired depth within the skin
WO2013022801A1 (en)	2011-08-05	2013-02-14	Forsight Vision4, Inc.	Small molecule delivery with implantable therapeutic device
US9500186B2 (en)	2010-02-01	2016-11-22	Medipacs, Inc.	High surface area polymer actuator with gas mitigating components
USD924406S1 (en)	2010-02-01	2021-07-06	Abbott Diabetes Care Inc.	Analyte sensor inserter
DK3622883T3 (da)	2010-03-24	2021-07-19	Abbott Diabetes Care Inc	Indførerer til medicinsk indretning og fremgangsmåder til at indføre og anvende medicinske indretninger
US20120070465A1 (en)	2010-03-29	2012-03-22	Astellas Pharma Inc.	Pharmaceutical composition for modified release
EP2558866B1 (de)	2010-04-15	2016-08-17	Tracon Pharmaceuticals, Inc.	Potenzierung einer antikrebs-wirkung durch eine kombinationstherapie mit ber-pfad-hemmern
EP2563759B1 (de)	2010-04-27	2022-04-06	Calcimedica, Inc.	Verbindungen als modulatoren von intrazellulärem calcium
DK2563776T3 (en)	2010-04-27	2016-09-19	Calcimedica Inc	Relations that modulate intracellular calcium
MX342405B (es)	2010-06-03	2016-09-28	Pharmacyclics Inc	El uso de inhibidores de la tirosina quinasa de bruton (btk).
US8635046B2 (en)	2010-06-23	2014-01-21	Abbott Diabetes Care Inc.	Method and system for evaluating analyte sensor response characteristics
US11064921B2 (en)	2010-06-29	2021-07-20	Abbott Diabetes Care Inc.	Devices, systems and methods for on-skin or on-body mounting of medical devices
US10092229B2 (en)	2010-06-29	2018-10-09	Abbott Diabetes Care Inc.	Calibration of analyte measurement system
ES2888906T3 (es)	2010-08-05	2022-01-10	Forsight Vision4 Inc	Aparato inyector para la administración de fármacos
AU2011285548B2 (en)	2010-08-05	2014-02-06	Forsight Vision4, Inc.	Combined drug delivery methods and apparatus
US9492315B2 (en)	2010-08-05	2016-11-15	Forsight Vision4, Inc.	Implantable therapeutic device
MX337711B (es)	2010-08-27	2016-03-15	Calcimedica Inc	Compuestos que modulan el calcio intracelular.
WO2012048168A2 (en)	2010-10-07	2012-04-12	Abbott Diabetes Care Inc.	Analyte monitoring devices and methods
US8668675B2 (en)	2010-11-03	2014-03-11	Flugen, Inc.	Wearable drug delivery device having spring drive and sliding actuation mechanism
US20140031769A1 (en)	2010-11-19	2014-01-30	Forsight Vision4, Inc.	Therapeutic agent formulations for implanted devices
US8518440B2 (en)	2010-12-21	2013-08-27	Confluent Surgical, Inc.	Biodegradable osmotic pump implant for drug delivery
EP3042654A1 (de)	2011-01-20	2016-07-13	Bionevia Pharmaceuticals Inc.	Zusammensetzungen mit veränderter freisetzung von epalrestat oder einem derivat davon und verwendungsverfahren dafür
US8801768B2 (en) *	2011-01-21	2014-08-12	Endologix, Inc.	Graft systems having semi-permeable filling structures and methods for their use
CA3115682C (en)	2011-02-28	2025-10-07	Abbott Diabetes Care Inc.	DEVICES, SYSTEMS AND METHODS ASSOCIATED WITH ANALYTE MONITORING DEVICES, AND DEVICES COMPRISING SAID ANALYTE MONITORING DEVICES
US10136845B2 (en)	2011-02-28	2018-11-27	Abbott Diabetes Care Inc.	Devices, systems, and methods associated with analyte monitoring devices and devices incorporating the same
DE102011007272A1 (de)	2011-04-13	2012-10-18	Bayer Pharma Aktiengesellschaft	Verzweigte 3-Phenylpropionsäure-Derivate und ihre Verwendung
WO2012142502A2 (en)	2011-04-15	2012-10-18	Dexcom Inc.	Advanced analyte sensor calibration and error detection
US9526770B2 (en)	2011-04-28	2016-12-27	Tissuetech, Inc.	Methods of modulating bone remodeling
EP2717888B1 (de)	2011-06-10	2020-09-09	Tissuetech, Inc.	Verfahren zur verarbeitung fötaler gewebesubstrate
WO2012174064A1 (en)	2011-06-14	2012-12-20	Bikam Pharmaceuticals, Inc.	Opsin-binding ligands, compositions and methods of use
EP4122384A1 (de)	2011-06-16	2023-01-25	Abbott Diabetes Care, Inc.	Analytüberwachungsvorrichtungen, -verfahren und -systeme mit temperaturkompensation
WO2012175698A1 (en)	2011-06-23	2012-12-27	Université Libre de Bruxelles	Therapeutic use of all-trans retinoic acid (atra) in patients suffering from alcoholic liver disease
EP4249059B1 (de)	2011-06-28	2025-07-30	ForSight Vision4, Inc.	Vorrichtung zum sammeln einer flüssigkeitsprobe aus einer reservoirkammer einer therapeutischen vorrichtung für das auge
CA2841785A1 (en) *	2011-07-06	2013-01-10	The Parkinson's Institute	Compositions and methods for treatment of symptoms in parkinson's disease patients
WO2013033636A2 (en)	2011-09-01	2013-03-07	University Of Southern California	Methods for preparing high throughput peptidomimetics, orally bioavailable drugs and compositions containing same
AU2011376953B2 (en)	2011-09-13	2017-08-24	Pharmacyclics Llc	Formulations of histone deacetylase inhibitor in combination with bendamustine and uses thereof
PT2755600T (pt)	2011-09-16	2021-04-19	Forsight Vision4 Inc	Aparelhos de troca de fluidos
CA2856703A1 (en)	2011-10-19	2013-04-25	Bikam Pharmaceuticals, Inc.	Opsin-binding ligands, compositions and methods of use
WO2013066849A1 (en)	2011-10-31	2013-05-10	Abbott Diabetes Care Inc.	Model based variable risk false glucose threshold alarm prevention mechanism
WO2013066873A1 (en)	2011-10-31	2013-05-10	Abbott Diabetes Care Inc.	Electronic devices having integrated reset systems and methods thereof
EP3677182B1 (de)	2011-11-07	2022-05-04	Abbott Diabetes Care Inc.	Analytüberwachungsvorrichtung und -verfahren
US8633178B2 (en)	2011-11-23	2014-01-21	Therapeuticsmd, Inc.	Natural combination hormone replacement formulations and therapies
US9301920B2 (en)	2012-06-18	2016-04-05	Therapeuticsmd, Inc.	Natural combination hormone replacement formulations and therapies
US8710993B2 (en)	2011-11-23	2014-04-29	Abbott Diabetes Care Inc.	Mitigating single point failure of devices in an analyte monitoring system and methods thereof
US9317656B2 (en)	2011-11-23	2016-04-19	Abbott Diabetes Care Inc.	Compatibility mechanisms for devices in a continuous analyte monitoring system and methods thereof
AU2012346214B2 (en)	2011-11-30	2017-09-14	Bikam Pharmaceuticals, Inc.	Opsin-binding ligands, compositions and methods of use
JP6322142B2 (ja)	2011-12-01	2018-05-09	ビカムファーマスーティカルス，インコーポレイテッド	オプシン結合性リガンド、組成物、及び使用方法
BR112014013649A2 (pt)	2011-12-06	2020-10-27	The Board Of Trustees Of The Leland Stanford Junior University	métodos e agentes para o tratamento de doenças virais e usos dos referidos agentes
AU2012352560B2 (en)	2011-12-11	2017-01-19	Abbott Diabetes Care Inc.	Analyte sensor devices, connections, and methods
WO2013096816A1 (en)	2011-12-22	2013-06-27	Biogen Idec Ma Inc.	Improved synthesis of amine substituted 4,5,6,7-tetrahydrobenzothiazole compounds
US8377946B1 (en)	2011-12-30	2013-02-19	Pharmacyclics, Inc.	Pyrazolo[3,4-d]pyrimidine and pyrrolo[2,3-d]pyrimidine compounds as kinase inhibitors
SI2800565T1 (sl)	2012-01-06	2020-10-30	Lundbeck La Jolla Research Center, Inc.	Karbamatne spojine in metode izdelave in uporabe le-teh
WO2013116061A1 (en)	2012-02-03	2013-08-08	Forsight Vision4, Inc.	Insertion and removal methods and apparatus for therapeutic devices
JP6170077B2 (ja)	2012-02-16	2017-07-26	エータイアーファーマ，インコーポレイテッド	自己免疫および炎症疾患を処置するためのヒスチジルｔＲＮＡ合成酵素
WO2013138524A1 (en)	2012-03-14	2013-09-19	Medipacs, Inc.	Smart polymer materials with excess reactive molecules
SG11201406363VA (en)	2012-05-07	2014-11-27	Bayer Pharma AG	Process for manufacturing a pharmaceutical dosage form comprising nifedipine and candesartan cilexetil
CA2875986C (en)	2012-06-04	2020-06-09	Pharmacyclics, Inc.	Crystalline forms of a bruton's tyrosine kinase inhibitor
US20150196640A1 (en)	2012-06-18	2015-07-16	Therapeuticsmd, Inc.	Progesterone formulations having a desirable pk profile
US10806697B2 (en)	2012-12-21	2020-10-20	Therapeuticsmd, Inc.	Vaginal inserted estradiol pharmaceutical compositions and methods
US10806740B2 (en)	2012-06-18	2020-10-20	Therapeuticsmd, Inc.	Natural combination hormone replacement formulations and therapies
US20130338122A1 (en)	2012-06-18	2013-12-19	Therapeuticsmd, Inc.	Transdermal hormone replacement therapies
UY34856A (es)	2012-07-03	2013-12-31	Bayer Pharma AG	Formas de presentación farmacéuticas que contienen 5-cloro-n-({(5s)-2-oxo-3-[4-(3-oxo-4- morfolinil)-fenil]-1,3-oxazolidin-5-il}-metil)-2-tiofencarboxamida
JP2015528001A (ja)	2012-07-11	2015-09-24	ティッシュテック，インク．	Ｈｃ−ｈａ／ｐｔｘ３複合体を含む組成物およびその使用方法
WO2014035732A1 (en)	2012-08-30	2014-03-06	Abbot Diabetes Care Inc.	Dropout detection in continuous analyte monitoring data during data excursions
US9968306B2 (en)	2012-09-17	2018-05-15	Abbott Diabetes Care Inc.	Methods and apparatuses for providing adverse condition notification with enhanced wireless communication range in analyte monitoring systems
US9907492B2 (en)	2012-09-26	2018-03-06	Abbott Diabetes Care Inc.	Method and apparatus for improving lag correction during in vivo measurement of analyte concentration with analyte concentration variability and range data
AU2013323206B2 (en)	2012-09-28	2017-07-20	Fred Hutchinson Cancer Center	Compounds and methods for preventing, treating and/or protecting against sensory hair cell death
EP3305299B1 (de)	2012-10-11	2020-04-29	Anaplasi Pharmaceuticals LLC	Verfahren und zusammensetzungen zur behandlung von schuppenflechte
US9717741B2 (en)	2012-10-11	2017-08-01	Anaplasi Pharmaceuticals Llc	Method and compositions for treating psoriasis
US9512116B2 (en)	2012-10-12	2016-12-06	Calcimedica, Inc.	Compounds that modulate intracellular calcium
US10537581B2 (en)	2012-12-21	2020-01-21	Therapeuticsmd, Inc.	Vaginal inserted estradiol pharmaceutical compositions and methods
US10471072B2 (en)	2012-12-21	2019-11-12	Therapeuticsmd, Inc.	Vaginal inserted estradiol pharmaceutical compositions and methods
US11246875B2 (en)	2012-12-21	2022-02-15	Therapeuticsmd, Inc.	Vaginal inserted estradiol pharmaceutical compositions and methods
US11266661B2 (en)	2012-12-21	2022-03-08	Therapeuticsmd, Inc.	Vaginal inserted estradiol pharmaceutical compositions and methods
US9180091B2 (en)	2012-12-21	2015-11-10	Therapeuticsmd, Inc.	Soluble estradiol capsule for vaginal insertion
US10568891B2 (en)	2012-12-21	2020-02-25	Therapeuticsmd, Inc.	Vaginal inserted estradiol pharmaceutical compositions and methods
GB2510826B (en)	2013-02-13	2015-09-02	Animax Ltd	Improvements in or relating to release of a beneficial substance from a bolus
CA2901280A1 (en)	2013-02-15	2014-08-21	Allergan, Inc.	Sustained drug delivery implant
US9662313B2 (en)	2013-02-28	2017-05-30	Knopp Biosciences Llc	Compositions and methods for treating amyotrophic lateral sclerosis in responders
EP2968113B8 (de)	2013-03-14	2020-10-28	Forsight Vision4, Inc.	Systeme zur verzögerten intraokularen abgabe schwerlöslicher verbindungen aus einem implantat mit einem portabgabesystem
US10433773B1 (en)	2013-03-15	2019-10-08	Abbott Diabetes Care Inc.	Noise rejection methods and apparatus for sparsely sampled analyte sensor data
US9474475B1 (en)	2013-03-15	2016-10-25	Abbott Diabetes Care Inc.	Multi-rate analyte sensor data collection with sample rate configurable signal processing
US10076285B2 (en)	2013-03-15	2018-09-18	Abbott Diabetes Care Inc.	Sensor fault detection using analyte sensor data pattern comparison
JP2016515523A (ja)	2013-03-15	2016-05-30	デュレクトコーポレーション	溶解変動性を低減させるためのレオロジー改質剤を有する組成物
EP2978393B1 (de)	2013-03-28	2023-12-27	ForSight Vision4, Inc.	Augenimplantat zur abgabe von therapeutischen substanzen
US9468630B2 (en)	2013-07-12	2016-10-18	Knopp Biosciences Llc	Compositions and methods for treating conditions related to increased eosinophils
EP4578509A3 (de)	2013-07-12	2025-11-19	Areteia Therapeutics, Inc.	Behandlung eines erhöhten spiegels von eosinophilen und/oder basophilen
HUE055850T2 (hu)	2013-08-13	2022-01-28	Knopp Biosciences Llc	Készítmények és módszerek a krónikus urticaria (csalánkiütés) kezelésére
WO2015023786A1 (en)	2013-08-13	2015-02-19	Knopp Biosciences Llc	Compositions and methods for treating plasma cell disorders and b-cell prolymphocytic disorders
SI3035991T1 (sl)	2013-08-19	2021-01-29	Taris Biomedical Llc	Večdelna naprava za dostavo zdravila
US9611263B2 (en)	2013-10-08	2017-04-04	Calcimedica, Inc.	Compounds that modulate intracellular calcium
JP6345786B2 (ja)	2013-12-05	2018-06-20	ファーマサイクリックスエルエルシー	ブルトン型チロシンキナーゼの阻害剤
WO2015102745A1 (en)	2013-12-31	2015-07-09	Abbott Diabetes Care Inc.	Self-powered analyte sensor and devices using the same
EP3865063A1 (de)	2014-03-30	2021-08-18	Abbott Diabetes Care, Inc.	Verfahren und vorrichtung zur bestimmung des starts einer mahlzeit und von spitzenwertereignissen in analytüberwachungssystemen
WO2015164213A1 (en)	2014-04-23	2015-10-29	The Research Foundation For The State University Of New York	A rapid and efficient bioorthogonal ligation reaction and boron-containing heterocycles useful in conjuction therewith
CA2947767A1 (en)	2014-05-22	2015-11-26	Therapeuticsmd, Inc.	Natural combination hormone replacement formulations and therapies
TW201603818A (zh)	2014-06-03	2016-02-01	組織科技股份有限公司	組成物及方法
KR102416726B1 (ko)	2014-07-15	2022-07-05	포사이트 비젼4, 인크.	안구 이식물 전달 디바이스 및 방법
CA2910865C (en)	2014-07-15	2016-11-29	Isa Odidi	Compositions and methods for reducing overdose
WO2016016770A1 (en)	2014-07-26	2016-02-04	Wockhardt Limited	A novel modified release pharmaceutical composition of sitagliptin or pharmaceutically acceptable salt thereof
US9474756B2 (en)	2014-08-08	2016-10-25	Forsight Vision4, Inc.	Stable and soluble formulations of receptor tyrosine kinase inhibitors, and methods of preparation thereof
US9839644B2 (en)	2014-09-09	2017-12-12	ARKAY Therapeutics, LLC	Formulations and methods for treatment of metabolic syndrome
US10500091B2 (en)	2014-11-10	2019-12-10	Forsight Vision4, Inc.	Expandable drug delivery devices and methods of use
US9359316B1 (en)	2014-11-25	2016-06-07	Concentric Analgesics, Inc.	Prodrugs of phenolic TRPV1 agonists
JP2018511355A (ja)	2015-01-28	2018-04-26	クロノセラピューティクスインコーポレイテッドＣｈｒｏｎｏＴｈｅｒａｐｅｕｔｉｃｓＩｎｃ．	薬剤送達方法及びシステム
KR102557184B1 (ko)	2015-02-06	2023-07-18	유니버시티 오브 워싱톤	감각 유모 세포 사멸을 예방 또는 치료하기 위한 화합물 및 방법
US10227333B2 (en)	2015-02-11	2019-03-12	Curtana Pharmaceuticals, Inc.	Inhibition of OLIG2 activity
WO2016132220A1 (en)	2015-02-20	2016-08-25	Osmotica Kereskedelmi Es Szolgaltato Kft	Controlled release oral dosage form of gaba receptor agonist
US20160243288A1 (en)	2015-02-23	2016-08-25	Tissuetech, Inc.	Apparatuses and methods for treating ophthalmic diseases and disorders
AU2016225000B2 (en)	2015-02-27	2021-04-01	Curtana Pharmaceuticals, Inc.	Inhibition of Olig2 activity
IL315294A (en)	2015-03-03	2024-10-01	Pharmacyclics Llc	Pharmaceutical formulations of bruton's tyrosine kinase inhibitor
US20180104251A1 (en)	2015-03-09	2018-04-19	Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College	Compositions and methods for the treatment of glioblastoma
AU2016228779A1 (en)	2015-03-12	2017-09-07	Chrono Therapeutics Inc.	Craving input and support system
MA41828A (fr)	2015-03-27	2018-01-30	Pharmacyclics Llc	Co-cristaux d'un inhibiteur de la tyrosine kinase de bruton
MA41827A (fr)	2015-03-27	2018-01-30	Pharmacyclics Llc	Formes solvatées d'un inhibiteur de la tyrosine kinase de bruton
US10575976B2 (en)	2015-04-30	2020-03-03	Dynamic Mouth Devices, L.L.C.	Method and apparatus for weight management utilizing an intra-oral device
MX2017014344A (es)	2015-05-11	2018-04-11	Abide Therapeutics Inc	Metodos para el tratamiento de la inflacion o el dolor neuropatico.
US10213139B2 (en)	2015-05-14	2019-02-26	Abbott Diabetes Care Inc.	Systems, devices, and methods for assembling an applicator and sensor control device
US10674944B2 (en)	2015-05-14	2020-06-09	Abbott Diabetes Care Inc.	Compact medical device inserters and related systems and methods
HK1250940A1 (zh)	2015-05-20	2019-01-18	Tissuetech, Inc.	用於预防上皮细胞的增殖和上皮-间充质转换的组合物和方法
WO2017011346A1 (en)	2015-07-10	2017-01-19	Abbott Diabetes Care Inc.	System, device and method of dynamic glucose profile response to physiological parameters
US10328087B2 (en)	2015-07-23	2019-06-25	Therapeuticsmd, Inc.	Formulations for solubilizing hormones
EP3328429B1 (de)	2015-07-31	2025-07-16	The Research Institute at Nationwide Children's Hospital	Peptide und antikörper zur beseitigung von biofilmen
JP2018525411A (ja)	2015-08-31	2018-09-06	ファーマサイクリックスエルエルシー	多発性骨髄腫を治療するためのｂｔｋ阻害剤の組み合わせ
EP3365027B1 (de)	2015-10-14	2022-03-30	Research Institute at Nationwide Children's Hospital	Hu-spezifische antikörper und deren verwendeng zur hemmung von biofilm
CA3005238A1 (en)	2015-11-20	2017-05-26	Forsight Vision4, Inc.	Porous structures for extended release drug delivery devices
JP2019505498A (ja)	2015-12-16	2019-02-28	ザ・ウォルター・アンド・エリザ・ホール・インスティテュート・オブ・メディカル・リサーチ	Ｎｋ細胞におけるサイトカイン誘導性ｓｈ２タンパク質の阻害
HK1259434A1 (zh)	2016-01-19	2019-11-29	Janssen Pharmaceutica Nv	包含btk抑制剂的配制品/组合物
US20190290650A1 (en)	2016-01-19	2019-09-26	Janssen Pharmaceutic Nv	Formulations/compositions comprising a btk inhibitor
TW201733600A (zh)	2016-01-29	2017-10-01	帝聖工業公司	胎兒扶持組織物及使用方法
WO2017147146A1 (en)	2016-02-23	2017-08-31	Concentric Analgesics, Inc.	Prodrugs of phenolic trpv1 agonists
WO2017173071A1 (en)	2016-04-01	2017-10-05	Therapeuticsmd, Inc.	Steroid hormone pharmaceutical composition
US10286077B2 (en)	2016-04-01	2019-05-14	Therapeuticsmd, Inc.	Steroid hormone compositions in medium chain oils
CA3054674A1 (en)	2016-04-04	2017-12-10	Sinopia Biosciences, Inc.	Treating extrapyramidal syndrome using trapidil
US11617680B2 (en)	2016-04-05	2023-04-04	Forsight Vision4, Inc.	Implantable ocular drug delivery devices
US10143687B2 (en)	2016-04-11	2018-12-04	Neurocea, LLC	Compositions and methods for treatment related to fall and fall frequency in neurodegenerative diseases
US10292977B2 (en)	2016-04-11	2019-05-21	Neurocea, LLC	Compositions and methods for treatment related to fall and fall frequency in neurodegenerative diseases
CN109562281B (zh)	2016-05-25	2021-12-17	同心镇痛药物公司	酚类trpv1激动剂的前药与局部麻醉药和血管收缩剂联合用于改善局部麻醉
WO2017205762A1 (en)	2016-05-27	2017-11-30	Pharmacyclics Llc	Inhibitors of interleukin-1 receptor-associated kinase
WO2017205769A1 (en)	2016-05-27	2017-11-30	Pharmacyclics Llc	Inhibitors of interleukin-1 receptor-associated kinase
WO2017205766A1 (en)	2016-05-27	2017-11-30	Pharmacyclics Llc	Inhibitors of interleukin-1 receptor-associated kinase
MY205229A (en)	2016-07-06	2024-10-08	Durect Corp	Oral dosage form with drug composition, barrier layer and drug layer
PT3484862T (pt)	2016-07-18	2021-11-17	Arthrosi Therapeutics Inc	Compostos, composições e métodos para o tratamento ou a prevenção de um sintoma associado a gota ou hiperuricemia
EP3504195A4 (de)	2016-08-26	2020-01-29	Curtana Pharmaceuticals, Inc.	Hemmung der olig2-aktivität
US10736905B1 (en)	2016-09-09	2020-08-11	Shahin Fatholahi	Nefopam dosage forms and methods of treatment
CA3043609A1 (en)	2016-11-16	2018-05-24	Abide Therapeutics, Inc.	Pharmaceutical formulations
BR112019010003A2 (pt)	2016-11-16	2019-08-20	Abide Therapeutics Inc	formas cristalinas de um inibidor de magl
WO2018129092A1 (en)	2017-01-04	2018-07-12	Research Institute At Nationwide Children's Hospital	Antibody fragments for the treatment of biofilm-related disorders
US11564982B2 (en)	2017-01-04	2023-01-31	Research Institute At Nationwide Children's Hospital	DNABII vaccines and antibodies with enhanced activity
WO2018129304A1 (en)	2017-01-06	2018-07-12	Chrono Therapeutics Inc.	Transdermal drug delivery devices and methods
CN115444410B (zh)	2017-01-23	2025-08-15	雅培糖尿病护理公司	用于插入体内分析物传感器的施加器及组件
US10702495B2 (en)	2017-02-20	2020-07-07	Nexien Biopharma, Inc.	Method and compositions for treating dystrophies and myotonia
WO2018175489A1 (en)	2017-03-21	2018-09-27	Abbott Diabetes Care Inc.	Methods, devices and system for providing diabetic condition diagnosis and therapy
WO2018200885A1 (en)	2017-04-26	2018-11-01	Neurocentria, Inc.	Magnesium compositions and methods of use
CN111315385A (zh)	2017-09-01	2020-06-19	华盛顿大学	用于预防或治疗感觉毛细胞死亡的化合物的晶型
US10736874B1 (en)	2017-09-08	2020-08-11	Shahin Fatholahi	Methods for treating pain associated with sickle cell disease
US11446311B2 (en)	2017-09-08	2022-09-20	Shahin Fatholahi	Methods for treating pain associated with sickle cell disease
US11331022B2 (en)	2017-10-24	2022-05-17	Dexcom, Inc.	Pre-connected analyte sensors
EP3700416B1 (de)	2017-10-24	2024-06-26	Dexcom, Inc.	Vorverbundene analytsensoren
JP7314155B2 (ja)	2017-11-21	2023-07-25	フォーサイト・ビジョン４・インコーポレーテッド	膨張可能ポート送達システムのための流体交換装置及びその使用方法
CA3091259A1 (en)	2018-02-16	2019-08-22	Esperion Therapeutics, Inc.	Sustained release formulations of bempedoic acid
US11685722B2 (en)	2018-02-28	2023-06-27	Curtana Pharmaceuticals, Inc.	Inhibition of Olig2 activity
US11759417B2 (en)	2018-02-28	2023-09-19	Shanghai Wd Pharmaceutical Co., Ltd	Pharmaceutical composition and preparation method therefor and use thereof
JP7195345B2 (ja)	2018-03-05	2022-12-23	アムニールコンプレックスプロダクツリサーチエルエルシー	薬物の時間放出のためのプログラム可能な医薬組成物
CN112118886B (zh)	2018-05-23	2022-08-23	上海汉都医药科技有限公司	活性药物成分的控释系统及其制备方法
US11911513B2 (en)	2018-05-23	2024-02-27	Shanghai Wd Pharmaceutical Co., Ltd	Controlled-release system of active pharmaceutical ingredient and preparation method therefor
EP3801732A4 (de)	2018-05-29	2022-04-27	Morningside Venture Investments Limited	Verfahren und systeme zur wirkstofffreisetzung
WO2020020790A1 (de)	2018-07-24	2020-01-30	Bayer Aktiengesellschaft	Oral applizierbare pharmazeutische darreichungsform mit modifizierter freisetzung
PE20210415A1 (es)	2018-07-24	2021-03-04	Bayer Ag	Forma de dosificacion farmaceutica administrable por via oral con liberacion modificada
US10905667B2 (en)	2018-07-24	2021-02-02	Bayer Pharma Aktiengesellschaft	Orally administrable modified-release pharmaceutical dosage form
AU2019310118A1 (en)	2018-07-27	2021-03-11	Concentric Analgesics, Inc.	Pegylated prodrugs of phenolic TRPV1 agonists
JP2022507660A (ja)	2018-11-16	2022-01-18	モーニングサイドベンチャーインベストメンツリミテッド	温度によって調節される経皮薬剤送達システム
EA202191543A1 (ru)	2018-12-06	2021-10-26	Артроси Терапьютикс, Инк.	Способы лечения или профилактики подагры или гиперурикемии
BR112021010708A2 (pt)	2018-12-06	2021-08-24	Arthrosi Therapeutics, Inc.	Formas cristalinas de um composto para tratar ou prevenir gota ou hiperuricemia
CN113195022A (zh)	2018-12-21	2021-07-30	雅培糖尿病护理公司	用于分析物传感器插入的系统、装置和方法
CN114040760B (zh)	2018-12-31	2025-05-09	拜欧米富士恩公司	Menin-mll相互作用的不可逆抑制剂
CA3133093A1 (en)	2019-03-15	2020-09-24	Unicycive Therapeutics, Inc.	Nicorandil derivatives
WO2020227319A1 (en)	2019-05-06	2020-11-12	Spinart, LLC	Formulations and methods for preparing stable cosmetic compositions
USD1002852S1 (en)	2019-06-06	2023-10-24	Abbott Diabetes Care Inc.	Analyte sensor device
EP3750528A1 (de)	2019-06-11	2020-12-16	Nexien Biopharma, Inc.	Zusammensetzungen zur behandlung von dystrophien und myotonie
CN114401986B (zh)	2019-07-08	2024-11-08	国家儿童医院研究所	破坏生物膜的抗体组合物
WO2021081117A2 (en)	2019-10-24	2021-04-29	Labombard Denis E	Ocular device and drug delivery system, with case
US11633405B2 (en)	2020-02-07	2023-04-25	Therapeuticsmd, Inc.	Steroid hormone pharmaceutical formulations
EP4110316A4 (de)	2020-02-26	2024-08-28	Case Western Reserve University	Zusammensetzungen und verfahren zur behandlung von fehlgefalteten protein-okular-erkrankungen
CN115916180A (zh)	2020-03-26	2023-04-04	希诺皮亚生物科学公司	同位素标记的曲匹地尔衍生物
CA3175210A1 (en)	2020-04-21	2021-10-28	Cheryl A. Grice	Synthesis of a monoacylglycerol lipase inhibitor
TW202208357A (zh)	2020-05-11	2022-03-01	美商克立弗治療學股份有限公司	VCP/p97抑制劑之結晶型及調配物
PL4153136T3 (pl)	2020-06-10	2024-06-24	Auspex Pharmaceuticals, Inc.	Osmotyczne postacie dawkowania zawierające deutetrabenazynę i sposoby ich stosowania
US12239463B2 (en)	2020-08-31	2025-03-04	Abbott Diabetes Care Inc.	Systems, devices, and methods for analyte sensor insertion
CN116033869A (zh)	2020-09-15	2023-04-28	雅培糖尿病护理公司	用于分析物监测的系统、装置和方法
WO2022133064A1 (en)	2020-12-16	2022-06-23	Biomea Fusion, Inc.	Fused pyrimidine compounds as inhibitors of menin-mll interaction
USD999913S1 (en)	2020-12-21	2023-09-26	Abbott Diabetes Care Inc	Analyte sensor inserter
WO2022150525A1 (en)	2021-01-06	2022-07-14	Awakn Life Sciences	Mdma in the treatment of alcohol use disorder
WO2022238507A1 (en)	2021-05-11	2022-11-17	Awakn Ls Europe Holdings Limited	Therapeutic aminoindane compounds and compositions
WO2022247952A1 (zh) *	2021-05-28	2022-12-01	上海博志研新药物技术有限公司	硝苯地平美托洛尔缓释组合物、其制备方法及应用
WO2022256720A2 (en)	2021-06-03	2022-12-08	Arcadia Medicine, Inc.	Enantiomeric entactogen compositions and methods of their use
JP2024531170A (ja)	2021-08-11	2024-08-29	バイオメアフュージョン，インコーポレイテッド	真性糖尿病に対するメニン－ｍｌｌ相互作用の共有結合性阻害剤
KR20240087693A (ko)	2021-08-20	2024-06-19	바이오메아 퓨전, 인크.	암 치료를 위한 비가역적 메닌-mll 억제제인 n-[4-[4-(4-모르폴리닐)-7h-피롤로[2,3-d]피리미딘-6-일]페닐]-4-[[3(r)-[(1-옥소-2-프로펜-1-일)아미노]-1-피페리디닐]메틸]-2-피리딘카르복스아미드의 결정질 형태
US12180176B2 (en)	2021-08-23	2024-12-31	Alexander Shulgin Research Institute, Inc.	Fluorinated empathogens
WO2023028091A1 (en)	2021-08-23	2023-03-02	Alexander Shulgin Research Institute	Deuterated empathogens
WO2023027966A1 (en)	2021-08-24	2023-03-02	Biomea Fusion, Inc.	Pyrazine compounds as irreversible inhibitors of flt3
EP4395827A4 (de)	2021-08-31	2025-07-02	Cerespir Incorporated	Co-kristalle
CA3230779A1 (en)	2021-09-03	2023-03-09	Paul Daley	Asymmetric allyl tryptamines
US20240409558A1 (en)	2021-09-13	2024-12-12	Biomea Fusion, Inc.	Irreversible inhibitors of kras
US12465578B2 (en)	2021-09-25	2025-11-11	Alexander Shulgin Research Institute, Inc.	Substituted alpha-ethyl phenylalkylamines
WO2023086341A1 (en)	2021-11-09	2023-05-19	Biomea Fusion, Inc.	Inhibitors of kras
KR102901738B1 (ko)	2021-11-16	2025-12-19	오즈온바이오 주식회사	산 민감성 무기성분을 포함하는 삼투성 제제 조성물
MX2024008057A (es)	2021-12-30	2024-08-28	Biomea Fusion Inc	Compuestos de pirazina como inhibidores de flt3.
WO2023139163A1 (en)	2022-01-19	2023-07-27	Awakn Ls Europe Holdings Limited	1,3-benzodioxole esters and their therapeutic use
USD1033637S1 (en)	2022-01-24	2024-07-02	Forsight Vision4, Inc.	Fluid exchange device
CN115490316B (zh) *	2022-01-24	2023-09-12	成都理工大学	一种可再利用的地下水营养物质缓释胶囊体
CA3244485A1 (en)	2022-02-16	2023-08-24	Awakn Ls Europe Holdings Limited	BRIDGED CYCLIC COMPOUNDS AND THEIR THERAPEUTIC USE AS CNS AGENTS
US20250353854A1 (en)	2022-06-03	2025-11-20	Biomea Fusion, Inc.	Fused pyrimidine compounds as inhibitors of menin
CN119384270A (zh)	2022-06-08	2025-01-28	奥斯佩克斯医药公司	包含氘代丁苯那嗪的渗透剂型及其使用方法
WO2024011142A1 (en)	2022-07-06	2024-01-11	Oppilan Pharma Limited	Crystalline forms of an s1p receptor modulator
US11931224B1 (en) *	2022-12-19	2024-03-19	Robert Parker	Tooth pod
TW202430528A (zh)	2023-01-18	2024-08-01	美商拜歐米富士恩股份有限公司	Ｎ－［４－［４－（４－嗎啉基）－７ｈ－吡咯並［２，３－ｄ］嘧啶－６－基］苯基］－４－［［３（ｒ）－［（１－氧代－２－丙烯－１－基）氨基］－１－哌啶基］甲基］－２－吡啶甲醯胺的結晶形式作為ｍｅｎｉｎ－ｍｌｌ相互作用的共價抑制劑
WO2024243402A2 (en)	2023-05-24	2024-11-28	Unicycive Therapeutics Inc.	Salt forms of nicorandil derivatives
WO2024249950A1 (en)	2023-06-02	2024-12-05	Biomea Fusion, Inc.	Fused pyrimidine compounds as inhibitors of menin
AU2024319536A1 (en)	2023-08-08	2026-02-26	United Therapeutics Corporation	A method of producing an oral osmotic pharmaceutical delivery system and a pharmaceutical batch produced using the same
WO2025072556A1 (en)	2023-09-26	2025-04-03	Unicycive Therapeutics, Inc.	Amino acid prodrugs of nicorandil
WO2025194102A1 (en)	2024-03-15	2025-09-18	Unicycive Therapeutics, Inc.	Pyridine modified nicorandil derivatives
WO2025208111A1 (en)	2024-03-29	2025-10-02	Biomea Fusion, Inc.	Heterocyclic glp-1r agonists

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3247066A (en) *	1962-09-12	1966-04-19	Parke Davis & Co	Controlled release dosage form containing water-swellable beadlet
US3867329A (en) *	1972-08-25	1975-02-18	Polysciences Inc	Composition for a hydrogel dilator article of manufacture and method for making same
US4203439A (en) *	1976-11-22	1980-05-20	Alza Corporation	Osmotic system with volume amplifier for increasing amount of agent delivered therefrom
US4111201A (en) *	1976-11-22	1978-09-05	Alza Corporation	Osmotic system for delivering selected beneficial agents having varying degrees of solubility
US4111202A (en) *	1976-11-22	1978-09-05	Alza Corporation	Osmotic system for the controlled and delivery of agent over time
US4111203A (en) *	1976-11-22	1978-09-05	Alza Corporation	Osmotic system with means for improving delivery kinetics of system
US4203440A (en) *	1978-10-23	1980-05-20	Alza Corporation	Device having variable volume chamber for dispensing useful agent
US4210139A (en) *	1979-01-17	1980-07-01	Alza Corporation	Osmotic device with compartment for governing concentration of agent dispensed from device
US4235236A (en) *	1979-02-12	1980-11-25	Alza Corporation	Device for dispensing drug by combined diffusional and osmotic operations

1980
- 1980-11-25 US US06/210,176 patent/US4327725A/en not_active Expired - Lifetime
1981
- 1981-07-22 AT AT81303354T patent/ATE15606T1/de not_active IP Right Cessation
- 1981-07-22 DE DE8181303354T patent/DE3172338D1/de not_active Expired
- 1981-07-22 EP EP81303354A patent/EP0052917B1/de not_active Expired
- 1981-09-21 JP JP56149298A patent/JPS6043045B2/ja not_active Expired
1992
- 1992-06-26 MX MX9203553A patent/MX174160B/es unknown

Also Published As

Publication number	Publication date
DE3172338D1 (en)	1985-10-24
EP0052917A3 (en)	1982-10-06
US4327725A (en)	1982-05-04
MX174160B (es)	1994-04-25
EP0052917A2 (de)	1982-06-02
JPS6043045B2 (ja)	1985-09-26
JPS5793065A (en)	1982-06-09
MX9203553A (es)	1992-09-01
EP0052917B1 (de)	1985-09-18

Legal Events

Date	Code	Title	Description
1986-01-15	UEP	Publication of translation of european patent specification
2001-10-15	EELA	Cancelled due to lapse of time

Publication	Publication Date	Title
ATE15606T1 (de)	1985-10-15	Durch osmose wirksame vorrichtung mit hydrogel als osmotisches mittel.
AR241676A1 (es)	1992-10-30	Suministrador de agente beneficioso a un ambiente de uso.
ES498887A0 (es)	1982-05-01	Perfeccionamientos introducidos en una bomba de fluido de accion simple, accionable acuaticamemte.
BR8106194A (pt)	1982-06-15	Bomba alternativa acionada por fluido
ES463854A1 (es)	1978-06-16	Metodo, con su dispositivo de realizacion, para la determi- nacion de microorganismos patogenos en fluidos fisiologicos.
DE3876150D1 (de)	1993-01-07	Vorrichtung zur ununterbrochenen mischung von waesserigen loesungen, insbesondere fuer schaumfeuerloeschsysteme.
BR8107931A (pt)	1982-09-14	Dispositivo para captar e explorar uma pressao,especialmente pressao de fluido
ES517079A0 (es)	1984-10-01	Procedimiento de inmuno-analisis para determinar una iodotironina en un fluido biologico.
ATE84440T1 (de)	1993-01-15	Gehaeuseende mit gewinde.
IT8022165A0 (it)	1980-05-19	Procedimento e dispositivo per la rivelazione in loco di un fluido di giacimento in un foro di trivellazione.
IT8124230A0 (it)	1981-09-30	Dispositivo modificatore del flusso di un fluido.
ES286420U (es)	1985-11-01	Dispositivo osmotico.
BR8100262A (pt)	1981-08-04	Valvula para adicionar ingredientes ou efetuar a amostragem do fluido de passagem atraves da valvula
IT7920294A0 (it)	1979-02-16	Dispositivo per la determinazione elettrochimica transcutanea della pressione parziale di ossigeno nel sangue.
ES513163A0 (es)	1983-06-01	Perfeccionamientos en dispositivos de compresion de fluidos.
SE8503705L (sv)	1987-02-06	Ventilanordning
ES508787A0 (es)	1982-11-01	Perfeccionamientos introducidos en una bomba de fluido de - desplazamiento positivo.
BR8406912A (pt)	1985-05-21	Sistema de pressao de fluido e dispositivo de valvula
IT8168070A0 (it)	1981-07-30	Procedimento per eliminare la torbidita di un fluido biologico e reagente utilizzabile nel procedimento
IT8121922A0 (it)	1981-05-22	Valvola e dispositivo per misurare la pressione sanguigna dotato di valvola.
BR8100364A (pt)	1981-08-11	Composicao contendo polimero hidrossoluvel, vazavel, liquida, para espessar meios aquosos, e fluido de tratamento ou perfuracao de pocos
ES501813A0 (es)	1982-11-01	Mejoras introducidas en dispositivos de acoplamiento por fluido viscoso, con cizalladura.
BR7702067A (pt)	1978-01-17	Dispositivo de valvula tripla operado por pressao de fluido;e dispositivo de valvula operado por pressao de fluido
NO155123C (no)	1987-02-18	Pumpeelement i en innretning for kunstig aandedrett.
IT1124956B (it)	1986-05-14	Dispositivo proporzionatore di portata di fluido