ATE159548T1 - Bifunktionelle wählbare fusionsgene - Google Patents

Bifunktionelle wählbare fusionsgene

Info

Publication number
ATE159548T1
ATE159548T1 AT92902004T AT92902004T ATE159548T1 AT E159548 T1 ATE159548 T1 AT E159548T1 AT 92902004 T AT92902004 T AT 92902004T AT 92902004 T AT92902004 T AT 92902004T AT E159548 T1 ATE159548 T1 AT E159548T1
Authority
AT
Austria
Prior art keywords
selectable
gene
fusion genes
phenotype
bifunctional
Prior art date
Application number
AT92902004T
Other languages
English (en)
Inventor
Stephen D Lupton
Original Assignee
Immunex Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Immunex Corp filed Critical Immunex Corp
Application granted granted Critical
Publication of ATE159548T1 publication Critical patent/ATE159548T1/de

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1205—Phosphotransferases with an alcohol group as acceptor (2.7.1), e.g. protein kinases
    • C12N9/1211—Thymidine kinase (2.7.1.21)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/62—DNA sequences coding for fusion proteins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/65—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression using markers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Medicinal Chemistry (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AT92902004T 1990-11-13 1991-11-12 Bifunktionelle wählbare fusionsgene ATE159548T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US61232690A 1990-11-13 1990-11-13

Publications (1)

Publication Number Publication Date
ATE159548T1 true ATE159548T1 (de) 1997-11-15

Family

ID=24452692

Family Applications (1)

Application Number Title Priority Date Filing Date
AT92902004T ATE159548T1 (de) 1990-11-13 1991-11-12 Bifunktionelle wählbare fusionsgene

Country Status (9)

Country Link
EP (1) EP0557459B1 (de)
JP (1) JP3150340B2 (de)
AT (1) ATE159548T1 (de)
AU (1) AU650085B2 (de)
CA (1) CA2096222C (de)
DE (1) DE69128037T2 (de)
DK (1) DK0557459T3 (de)
IE (1) IE913929A1 (de)
WO (1) WO1992008796A1 (de)

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JPH06504432A (ja) 1994-05-26
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CA2096222A1 (en) 1992-05-14
DE69128037D1 (de) 1997-11-27
DK0557459T3 (da) 1997-12-15
WO1992008796A1 (en) 1992-05-29
EP0557459B1 (de) 1997-10-22
DE69128037T2 (de) 1998-05-07
CA2096222C (en) 1998-12-29
JP3150340B2 (ja) 2001-03-26
AU9081591A (en) 1992-06-11

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