ATE159763T1 - Nuklein-säure amplifikation mit dns abhängigen rns polymerasen aktivität von rns-replikasen - Google Patents

Nuklein-säure amplifikation mit dns abhängigen rns polymerasen aktivität von rns-replikasen

Info

Publication number
ATE159763T1
ATE159763T1 AT92903684T AT92903684T ATE159763T1 AT E159763 T1 ATE159763 T1 AT E159763T1 AT 92903684 T AT92903684 T AT 92903684T AT 92903684 T AT92903684 T AT 92903684T AT E159763 T1 ATE159763 T1 AT E159763T1
Authority
AT
Austria
Prior art keywords
rna
nucleic acid
acid amplification
replicases
dna dependent
Prior art date
Application number
AT92903684T
Other languages
English (en)
Inventor
Randall L Dimond
Steven J Ekenberg
James R Hartnett
Geoffrey R Hudson
Christopher L Jones
Mark A Maffitt
Richard A Martinelli
Leopoldo G Mendoza
Katherine M Miller
John E Monahan
Edward E Pahuski
James W Schumm
Original Assignee
Promega Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Promega Corp filed Critical Promega Corp
Application granted granted Critical
Publication of ATE159763T1 publication Critical patent/ATE159763T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/6867—Replicase-based amplification, e.g. using Q-beta replicase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6806—Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/6853—Nucleic acid amplification reactions using modified primers or templates

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Analytical Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AT92903684T 1990-12-31 1991-12-31 Nuklein-säure amplifikation mit dns abhängigen rns polymerasen aktivität von rns-replikasen ATE159763T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US63850890A 1990-12-31 1990-12-31

Publications (1)

Publication Number Publication Date
ATE159763T1 true ATE159763T1 (de) 1997-11-15

Family

ID=24560333

Family Applications (1)

Application Number Title Priority Date Filing Date
AT92903684T ATE159763T1 (de) 1990-12-31 1991-12-31 Nuklein-säure amplifikation mit dns abhängigen rns polymerasen aktivität von rns-replikasen

Country Status (11)

Country Link
US (3) US6090589A (de)
EP (1) EP0519053B1 (de)
JP (1) JP3183510B2 (de)
KR (1) KR100231383B1 (de)
AT (1) ATE159763T1 (de)
AU (2) AU9165091A (de)
CA (1) CA2076750C (de)
DE (1) DE69128077T2 (de)
DK (1) DK0519053T3 (de)
ES (1) ES2108748T3 (de)
WO (1) WO1992012261A1 (de)

Families Citing this family (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2663292A (en) * 1991-09-10 1993-04-05 Jack D. Love Dna/rna target and signal amplification
AU6088094A (en) * 1993-01-15 1994-08-15 General Hospital Corporation, The Rna assays using rna binary probes and ribozyme ligase
DE69434688T2 (de) * 1993-01-15 2007-01-11 The Public Health Research Institute Of The City Of New York, Inc. Diagnostischer nachweis von rna und reagentiensätze unter verwendung binärer rna proben und einer rna-abhängigen rna ligase
US5942391A (en) 1994-06-22 1999-08-24 Mount Sinai School Of Medicine Nucleic acid amplification method: ramification-extension amplification method (RAM)
USRE38442E1 (en) * 1994-06-22 2004-02-24 Mount Sinai School Of Medicine Nucleic acid amplification method hybridization signal amplification method (HSAM)
US5876924A (en) * 1994-06-22 1999-03-02 Mount Sinai School Of Medicine Nucleic acid amplification method hybridization signal amplification method (HSAM)
US6593086B2 (en) 1996-05-20 2003-07-15 Mount Sinai School Of Medicine Of New York University Nucleic acid amplification methods
FR2723591B1 (fr) * 1994-08-10 1996-09-20 Cis Bio Int Methode d'amplification et/ou de detection d'une sequence d'acide nucleique, reactif de detection et ses applications.
US5753787A (en) * 1995-04-10 1998-05-19 Yale University Nucleic acids encoding ancylostoma secreted protein
US5837466A (en) * 1996-12-16 1998-11-17 Vysis, Inc. Devices and methods for detecting nucleic acid analytes in samples
US6001570A (en) * 1997-02-18 1999-12-14 Invitro Diagnostics, Inc. Compositions, methods, kits and apparatus for determining the presence or absence of target molecules
US6108582A (en) * 1998-07-02 2000-08-22 Intermedics Inc. Cardiac pacemaker lead with extendable/retractable fixation
US6463334B1 (en) 1998-11-02 2002-10-08 Cardiac Pacemakers, Inc. Extendable and retractable lead
WO2001059162A2 (en) * 2000-02-08 2001-08-16 Bayer Corporation METHOD FOR NUCLEIC ACID DETECTION VIA Qβ REPLICASE
US6562575B1 (en) 2000-06-26 2003-05-13 Epicentre Technologies Corporation Analyte-specific assays based on formation of a replicase substrate
US6949340B2 (en) * 2001-03-28 2005-09-27 Creative Mines Llc Optical phase modulator
GB0111275D0 (en) * 2001-05-09 2001-06-27 Secr Defence Analytical method and kit
US10539561B1 (en) * 2001-08-30 2020-01-21 Customarray, Inc. Enzyme-amplified redox microarray detection process
US20120077196A9 (en) * 2001-09-03 2012-03-29 Guido Krupp Universal method for selective amplification of mRNAs
DE10143106C1 (de) * 2001-09-03 2002-10-10 Artus Ges Fuer Molekularbiolog Vermehrung von Ribonukleinsäuren
US6972173B2 (en) * 2002-03-14 2005-12-06 Intel Corporation Methods to increase nucleotide signals by raman scattering
US7238477B2 (en) * 2001-09-24 2007-07-03 Intel Corporation Methods to increase nucleotide signals by Raman scattering
US6852492B2 (en) * 2001-09-24 2005-02-08 Intel Corporation Nucleic acid sequencing by raman monitoring of uptake of precursors during molecular replication
US7476501B2 (en) * 2002-03-26 2009-01-13 Intel Corporation Methods and device for DNA sequencing using surface enhanced raman scattering (SERS)
US20040110208A1 (en) * 2002-03-26 2004-06-10 Selena Chan Methods and device for DNA sequencing using surface enhanced Raman scattering (SERS)
US20030215816A1 (en) * 2002-05-20 2003-11-20 Narayan Sundararajan Method for sequencing nucleic acids by observing the uptake of nucleotides modified with bulky groups
DE10224200C1 (de) * 2002-05-31 2003-08-21 Artus Ges Fuer Molekularbiolog Vermehrung von Ribonukleinsäuren
DE10240868A1 (de) * 2002-09-04 2004-03-18 Artus Gesellschaft für molekularbiologische Diagnostik und Entwicklung mbH Verbesserte Verfahren zur Synthese von Nukleinsäuren
GB0230238D0 (en) * 2002-12-28 2003-02-05 Fu Guoliang Combined exponential and linear amplification
CA2515075C (en) 2003-02-05 2012-10-02 Iquum, Inc. Sample processing
WO2004092197A2 (en) * 2003-04-07 2004-10-28 The Regents Of The University Of California Amyloid-specific peptides and uses thereof
US20060199194A1 (en) * 2003-11-10 2006-09-07 Q-Rna, Inc. Methods of detection using immuno-Q-Amp technology
US20050214805A1 (en) * 2003-11-10 2005-09-29 Q-Rna, Inc. Methods of detection employing immuno-Q-Amp technology
US7245973B2 (en) 2003-12-23 2007-07-17 Cardiac Pacemakers, Inc. His bundle mapping, pacing, and injection lead
GB0517005D0 (en) * 2005-08-19 2005-09-28 Enigma Diagnostics Ltd Analytical method and kit
US20070065834A1 (en) * 2005-09-19 2007-03-22 Hillis William D Method and sequences for determinate nucleic acid hybridization
US20080003564A1 (en) * 2006-02-14 2008-01-03 Iquum, Inc. Sample processing
US20130183718A1 (en) * 2010-09-21 2013-07-18 RibpxX GmbH Method for Synthesizing RNA using DNA Template
US8741564B2 (en) 2011-05-04 2014-06-03 Htg Molecular Diagnostics, Inc. Quantitative nuclease protection assay (QNPA) and sequencing (QNPS) improvements

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4786600A (en) * 1984-05-25 1988-11-22 The Trustees Of Columbia University In The City Of New York Autocatalytic replication of recombinant RNA
US4957858A (en) * 1986-04-16 1990-09-18 The Salk Instute For Biological Studies Replicative RNA reporter systems
CA1339981C (en) * 1984-05-25 1998-08-04 Fred R. Kramer Replicatable hybridizable recombinant rna probes and methods of using same
DK171161B1 (da) 1985-03-28 1996-07-08 Hoffmann La Roche Fremgangsmåde til påvisning af forekomst eller fravær af mindst én specifik nukleinsyresekvens i en prøve eller til skelnen mellem to forskellige nukleinsyresekvenser i denne prøve
IL86724A (en) * 1987-06-19 1995-01-24 Siska Diagnostics Inc Methods and kits for amplification and testing of nucleic acid sequences
JP2939485B2 (ja) * 1988-09-08 1999-08-25 ザ・ソーク・インスチュート・フォーバイオロジカル・スタディーズ 複製ｒｎａに基づく増幅／検出系
CA1339991C (en) 1988-09-08 1998-08-11 The Trustees Of Columbia University Replicative rna-based amplification/detection system
KR0148265B1 (ko) * 1988-12-16 1998-10-15 에프.지이.엠 헤르만스 자가-지속 서열 복제 시스템
US5112734A (en) * 1989-05-26 1992-05-12 Gene-Trak Systems Target-dependent synthesis of an artificial gene for the synthesis of a replicatable rna
EP0731175A3 (de) * 1989-07-11 2004-05-26 Gen-Probe Incorporated Oligonukleotid-Sonden für Nukleinsäure von HIV
CA2040503A1 (en) * 1990-04-25 1991-10-26 Gene-Trak Systems Selective amplification system using q beta replicase

Also Published As

Publication number Publication date
US6090589A (en) 2000-07-18
KR100231383B1 (ko) 1999-11-15
EP0519053A4 (en) 1993-03-31
US6677140B2 (en) 2004-01-13
AU9165091A (en) 1992-08-17
EP0519053B1 (de) 1997-10-29
DE69128077D1 (de) 1997-12-04
JPH05505111A (ja) 1993-08-05
CA2076750C (en) 2003-07-08
AU2022295A (en) 1995-09-21
DE69128077T2 (de) 1998-02-26
CA2076750A1 (en) 1992-07-01
DK0519053T3 (da) 1998-07-20
JP3183510B2 (ja) 2001-07-09
ES2108748T3 (es) 1998-01-01
US20020192677A1 (en) 2002-12-19
US6369207B1 (en) 2002-04-09
EP0519053A1 (de) 1992-12-23
WO1992012261A1 (en) 1992-07-23
AU694199B2 (en) 1998-07-16

Similar Documents

Publication Publication Date Title
ATE159763T1 (de) Nuklein-säure amplifikation mit dns abhängigen rns polymerasen aktivität von rns-replikasen
DK0408295T3 (da) Fremgangsmåder til opformering af nukleinsyresekvenser
DK337587A (da) Alkynylamino-nucleotider og deres fremstilling samt ved fremstillingen anvendelige 7-iodnucleotider
DK0698105T3 (da) Nukleotidsekvenser til styring af ekspressionen af DNAsekvenser i en værtscelle
DE60142709D1 (de) Methoden und zusammensetzungen zur generierung einer vielzahl von kopien von nukleinsäuresequenzen und methoden zur detektion derselben
ATE394410T1 (de) Hochspezifische primer, amplifizierungsverfahren und kits
ATE236269T1 (de) Ein elektrochemiluminescenter nachweis von nukleinsäuren auf basis der selbsttragenden sequenzreplikation
DE69334092D1 (de) Nachweis von Mycobacterium tuberculosis durch Vervielfältigung von Nukleinsäuresequenzen
KR920014937A (ko) 사슬 치환에 의한 증폭방법
CA2084790A1 (en) Endonucleases
DK496185A (da) Autonome replikationssekvenser for gaerstammer af slaegten pichia
DE60229050D1 (de) Verfahren zur herstellung von ascorbinsäurezwischenprodukten in wirtszellen
ATE203775T1 (de) Methode zur detektion einer gezielten nukleinsäure
DK0404625T3 (da) Oligonukleotidsekvenser til amplifikation af genomer af retrovirus af HIV-2 og SIV-typen samt deres anvendelser til in vitro-diagnose af infektioner forårsaget af disse virus
DE69114844D1 (de) Enzymatisches amplifizierungsverfahren in vitro.
WO1990009457A3 (en) Oligonucleotide primer pairs for sequence independent gene amplification and methods which employ them
ATE231922T1 (de) Modifizierung von oligonukleotid-primer-sequenzen zum manipilieren der zugabe von nicht-template- nukleotiden
DE69610933D1 (de) Verfahren und reagenzien zur typisierung von hla-genen der klasse i
ATE470710T1 (de) Auf nasba basiertes detektionsverfahren zur detektion des tuberkelbazillus
DK0463043T3 (da) Fremgangsmåde til stabilisering af hybridiseringen af komplementære polynukleotidsekvenser
ES2090312T3 (es) Segmentos de adn y microorganismos transformados que comprenden el gen de la delta-1-deshidrogenasa, y sus aplicaciones.
FI875543A7 (fi) Puhdistettu lämpöstabiili entsyymi ja menetelmä nukleiinihapposekvenssien vahvistamiseksi, havaitsemiseksja/tai kloonaamiseksi tätä entsyymiä käyttäen.

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee