ATE163674T1 - Klonierung und sequenzierung von dermatophagoiden (hausstaubmilben) allergenen - Google Patents

Klonierung und sequenzierung von dermatophagoiden (hausstaubmilben) allergenen

Info

Publication number
ATE163674T1
ATE163674T1 AT93921462T AT93921462T ATE163674T1 AT E163674 T1 ATE163674 T1 AT E163674T1 AT 93921462 T AT93921462 T AT 93921462T AT 93921462 T AT93921462 T AT 93921462T AT E163674 T1 ATE163674 T1 AT E163674T1
Authority
AT
Austria
Prior art keywords
allergens
der
house dust
farinae
dna encoding
Prior art date
Application number
AT93921462T
Other languages
English (en)
Inventor
Wayne R Thomas
Kaw-Yan Chua
Original Assignee
Tvw Telethon Inst Child Health
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tvw Telethon Inst Child Health filed Critical Tvw Telethon Inst Child Health
Application granted granted Critical
Publication of ATE163674T1 publication Critical patent/ATE163674T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/43504Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
    • C07K14/43513Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from arachnidae
    • C07K14/43531Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from arachnidae from mites
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52Cytokines; Lymphokines; Interferons
    • C07K14/54Interleukins [IL]
    • C07K14/5403IL-3
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00Chemistry: analytical and immunological testing
    • Y10S436/826Additives, e.g. buffers, diluents, preservatives

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Insects & Arthropods (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Pulmonology (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT93921462T 1992-09-10 1993-09-10 Klonierung und sequenzierung von dermatophagoiden (hausstaubmilben) allergenen ATE163674T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/945,288 US5433948A (en) 1990-02-13 1992-09-10 Cloning and sequencing of allergens of dermatophagoides (house dust mite)

Publications (1)

Publication Number Publication Date
ATE163674T1 true ATE163674T1 (de) 1998-03-15

Family

ID=25482920

Family Applications (1)

Application Number Title Priority Date Filing Date
AT93921462T ATE163674T1 (de) 1992-09-10 1993-09-10 Klonierung und sequenzierung von dermatophagoiden (hausstaubmilben) allergenen

Country Status (12)

Country Link
US (4) US5433948A (de)
EP (1) EP0662129B1 (de)
JP (1) JP3487852B2 (de)
AT (1) ATE163674T1 (de)
AU (1) AU680202B2 (de)
CA (1) CA2144055C (de)
DE (1) DE69317292T2 (de)
DK (1) DK0662129T3 (de)
ES (1) ES2112996T3 (de)
GR (1) GR3026711T3 (de)
NZ (1) NZ256255A (de)
WO (1) WO1994005790A1 (de)

Families Citing this family (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5433948A (en) * 1990-02-13 1995-07-18 Thomas; Wayne R. Cloning and sequencing of allergens of dermatophagoides (house dust mite)
JP2596466B2 (ja) * 1990-03-03 1997-04-02 アサヒビール株式会社 ダニの主要アレルゲンの還伝情報を有するdnaおよび該アレルゲンの製造方法
US7288256B1 (en) * 1991-10-16 2007-10-30 Merck Patent Gmbh T cell epitopes of the major allergens from dermatophagoides (house dust mite)
US6254869B1 (en) * 1996-03-27 2001-07-03 The Regents Of The University Of California Cryptopain vaccines, antibodies, proteins, peptides, DNA and RNA for prophylaxis, treatment and diagnosis and for detection of cryptosporidium species
JP3520089B2 (ja) * 1993-12-22 2004-04-19 アサヒビール株式会社 新規な組換えDerlアレルゲン物質、そのプロ体及びこれらの産生方法
ATE207617T1 (de) * 1995-03-24 2001-11-15 Vorwerk Co Interholding Verfahren zur untersuchung von hausstaub
JP3316535B2 (ja) * 1995-03-28 2002-08-19 アサヒビール株式会社 ダニアレルゲンの改変体およびその製造法
US6737406B1 (en) 1996-03-21 2004-05-18 Circassia, Ltd. Cryptic peptides and method for their identification
EP1027435A2 (de) * 1997-10-02 2000-08-16 Max-Planck-Gesellschaft Zur Förderung Der Wissenschaften E.V. Nukleinsäuremolekül kodierend für ein (poly)peptid, das in mutierter form mit autoimmuner polyendokrinopather candidose ektodermaler dystrophy (apedec) cosegregiert
GB9724531D0 (en) * 1997-11-19 1998-01-21 Smithkline Biolog Novel compounds
US6455686B1 (en) * 1998-04-17 2002-09-24 Heska Corporation Dermatophagoides nucleic acid molecules, proteins and uses thereof
US7128921B1 (en) * 1998-04-17 2006-10-31 Heska Corporation Dermatophagoides proteins and fragments thereof
WO2001029078A2 (en) * 1999-10-15 2001-04-26 Heska Corporation Method for production and use of mite group 1 proteins
WO2001077353A2 (en) * 2000-04-05 2001-10-18 Syngenta Participations Ag Expression of pollen allergens in plastids
GB0014288D0 (en) * 2000-06-10 2000-08-02 Smithkline Beecham Biolog Vaccine
US20020168782A1 (en) * 2001-01-03 2002-11-14 Mccall Catherine A. Detection of allergen-specific IgE
FR2822709B1 (fr) * 2001-03-30 2007-01-19 Antialis Composition pharmaceutique anti-allergique comprenant au moins un allergene et au moins un compose antihistaminique
US7927600B2 (en) * 2001-03-30 2011-04-19 Emile Loria Anti-allergic pharmaceutical composition containing at least one allergen and at least one antihistamine compound
GB0120150D0 (en) * 2001-08-17 2001-10-10 Glaxosmithkline Biolog Sa Novel compounds
AU2003246586A1 (en) * 2002-07-10 2004-02-02 Merck Patent Gmbh Variants of the house dust mite allergen der f2
US20060251667A1 (en) * 2002-08-29 2006-11-09 Chua Kaw Y Recombinant nucleic acid useful for inducing protective immune response against allergens
EP1756275A1 (de) * 2004-04-23 2007-02-28 Novozymes A/S Verfahren zur gewinnung reifer protease durch enzymatische verdauung
AT501101B1 (de) * 2004-12-02 2008-01-15 Biomay Ag Protein-allergen-derivat
US7334521B2 (en) * 2005-02-25 2008-02-26 Cosco Industries, Inc. Hand held two-ended ink stamper
US20070238750A1 (en) * 2006-04-07 2007-10-11 Michalis Nicolaou Pure isomers of tritoqualine
ES2709176T3 (es) 2006-08-11 2019-04-15 Life Sciences Res Partners Vzw Péptidos inmunogénicos y su uso en trastornos inmunitarios
EP2526938A3 (de) * 2007-02-12 2013-06-12 Mike Nicolaou Hinstidindecarboxylasehemmern allein oder kombiniert mit einem Leukotriene Rezeptor Antagonist, einem Anti-H1 und/oder einem Anti-H2 zur Behandlung von COPD oder gastrointestinalen Erkrankungen
NZ583362A (en) * 2007-08-15 2012-06-29 Circassia Ltd Peptide with reduced dimer formation
ES2637812T3 (es) 2008-02-14 2017-10-17 Life Sciences Research Partners Vzw Inmunoterapia dirigida a patógenos intracelulares
EP2626081B1 (de) 2008-02-14 2017-03-22 Life Sciences Research Partners VZW Immunogene Beeinflussung von Tumoren und Tumorzellen
CA2718994C (en) * 2008-03-25 2017-06-13 Bial Industrial Farmaceutica, S.A. Hypoallergenic hybrid proteins of major group 1 and 2 mite allergens for use in the treatment of allergies
DE11787873T1 (de) 2010-11-25 2013-12-12 Imnate Sarl Immugene Peptide zur Verwendung bei der Vorbeugung und/oder Behandlung von Infektionskrankheiten, Autoimmunerkrankungen, Immunreaktionen auf Allofaktoren, allergischen Erkrankungen, Tumoren, Transplantatabstossungen und Immunreaktionen auf virale Vektoren
GB201201511D0 (en) * 2012-01-30 2012-03-14 Univ Leuven Kath Modified epitopes for boosting CD4+ T-cell responses
GB201309469D0 (en) 2013-05-28 2013-07-10 Imcyse Sa Detection of CD4+ T lymphocytes
GB201418433D0 (en) 2014-10-17 2014-12-03 Imcyse Sa Novel immunogenic peptides
US10729791B2 (en) 2015-05-18 2020-08-04 Imcyse Sa Animal models for evaluating pharmaceutical compounds
CA2995771A1 (en) 2015-09-25 2017-03-30 Imcyse Sa Improved methods and compounds for eliminating immune responses to therapeutic agents
BR112018071466A2 (pt) 2016-04-19 2019-03-19 Imcyse Sa novos peptídeos de ligação a cd1d imunogênicos

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5026545A (en) * 1984-09-17 1991-06-25 Baxter International, Inc. Treatment of allergy and composition therefor
JP2993967B2 (ja) * 1987-06-17 1999-12-27 インスティテュート・フォー・チャイルド・ヘルス・リサーチ ダニアレルゲンのクローニング
JP2787162B2 (ja) * 1989-08-24 1998-08-13 フマキラー株式会社 精製ダニアレルゲン
US5433948A (en) * 1990-02-13 1995-07-18 Thomas; Wayne R. Cloning and sequencing of allergens of dermatophagoides (house dust mite)
JP2596466B2 (ja) * 1990-03-03 1997-04-02 アサヒビール株式会社 ダニの主要アレルゲンの還伝情報を有するdnaおよび該アレルゲンの製造方法
JP3139777B2 (ja) * 1990-08-27 2001-03-05 フマキラー株式会社 組換えダニアレルゲン
DE69131131T2 (de) * 1990-09-11 1999-10-14 Institute For Child Health Research Klonierung und sequenzierung von dermatophagoiden-antigenen (hausstaubmilben)
DE69233772D1 (de) * 1991-10-16 2009-11-12 Merck Patent Gmbh T-zell epitopen von den wichtigsten allergene von dermatophagoides (hausmilbe)

Also Published As

Publication number Publication date
AU680202B2 (en) 1997-07-24
CA2144055A1 (en) 1994-03-17
US5770202A (en) 1998-06-23
US5433948A (en) 1995-07-18
DK0662129T3 (da) 1998-03-30
GR3026711T3 (en) 1998-07-31
US5552142A (en) 1996-09-03
DE69317292D1 (de) 1998-04-09
DE69317292T2 (de) 1998-06-18
WO1994005790A1 (en) 1994-03-17
CA2144055C (en) 1999-11-02
EP0662129A1 (de) 1995-07-12
US5773002A (en) 1998-06-30
EP0662129B1 (de) 1998-03-04
AU4854893A (en) 1994-03-29
ES2112996T3 (es) 1998-04-16
NZ256255A (en) 1999-03-29
JP3487852B2 (ja) 2004-01-19
JPH08504179A (ja) 1996-05-07

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