ATE163674T1 - Klonierung und sequenzierung von dermatophagoiden (hausstaubmilben) allergenen - Google Patents
Klonierung und sequenzierung von dermatophagoiden (hausstaubmilben) allergenenInfo
- Publication number
- ATE163674T1 ATE163674T1 AT93921462T AT93921462T ATE163674T1 AT E163674 T1 ATE163674 T1 AT E163674T1 AT 93921462 T AT93921462 T AT 93921462T AT 93921462 T AT93921462 T AT 93921462T AT E163674 T1 ATE163674 T1 AT E163674T1
- Authority
- AT
- Austria
- Prior art keywords
- allergens
- der
- house dust
- farinae
- dna encoding
- Prior art date
Links
- 239000013566 allergen Substances 0.000 title abstract 7
- 229960004784 allergens Drugs 0.000 title abstract 6
- 241000238710 Dermatophagoides Species 0.000 title abstract 2
- 241000238711 Pyroglyphidae Species 0.000 title abstract 2
- 229940046533 house dust mites Drugs 0.000 title abstract 2
- 238000010367 cloning Methods 0.000 title 1
- 238000012163 sequencing technique Methods 0.000 title 1
- 108090000623 proteins and genes Proteins 0.000 abstract 5
- 102000004169 proteins and genes Human genes 0.000 abstract 5
- 241000238713 Dermatophagoides farinae Species 0.000 abstract 3
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 3
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 3
- 108010055622 Dermatophagoides farinae antigen f 1 Proteins 0.000 abstract 1
- 241000238740 Dermatophagoides pteronyssinus Species 0.000 abstract 1
- 108010061629 Dermatophagoides pteronyssinus antigen p 1 Proteins 0.000 abstract 1
- 108010061608 Dermatophagoides pteronyssinus antigen p 2 Proteins 0.000 abstract 1
- 239000003153 chemical reaction reagent Substances 0.000 abstract 1
- 239000000428 dust Substances 0.000 abstract 1
- 102000054765 polymorphisms of proteins Human genes 0.000 abstract 1
- 230000035945 sensitivity Effects 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/43504—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
- C07K14/43513—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from arachnidae
- C07K14/43531—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from arachnidae from mites
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/54—Interleukins [IL]
- C07K14/5403—IL-3
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/826—Additives, e.g. buffers, diluents, preservatives
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Toxicology (AREA)
- Insects & Arthropods (AREA)
- Tropical Medicine & Parasitology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Pulmonology (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US07/945,288 US5433948A (en) | 1990-02-13 | 1992-09-10 | Cloning and sequencing of allergens of dermatophagoides (house dust mite) |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE163674T1 true ATE163674T1 (de) | 1998-03-15 |
Family
ID=25482920
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT93921462T ATE163674T1 (de) | 1992-09-10 | 1993-09-10 | Klonierung und sequenzierung von dermatophagoiden (hausstaubmilben) allergenen |
Country Status (12)
| Country | Link |
|---|---|
| US (4) | US5433948A (de) |
| EP (1) | EP0662129B1 (de) |
| JP (1) | JP3487852B2 (de) |
| AT (1) | ATE163674T1 (de) |
| AU (1) | AU680202B2 (de) |
| CA (1) | CA2144055C (de) |
| DE (1) | DE69317292T2 (de) |
| DK (1) | DK0662129T3 (de) |
| ES (1) | ES2112996T3 (de) |
| GR (1) | GR3026711T3 (de) |
| NZ (1) | NZ256255A (de) |
| WO (1) | WO1994005790A1 (de) |
Families Citing this family (38)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5433948A (en) * | 1990-02-13 | 1995-07-18 | Thomas; Wayne R. | Cloning and sequencing of allergens of dermatophagoides (house dust mite) |
| JP2596466B2 (ja) * | 1990-03-03 | 1997-04-02 | アサヒビール株式会社 | ダニの主要アレルゲンの還伝情報を有するdnaおよび該アレルゲンの製造方法 |
| US7288256B1 (en) * | 1991-10-16 | 2007-10-30 | Merck Patent Gmbh | T cell epitopes of the major allergens from dermatophagoides (house dust mite) |
| US6254869B1 (en) * | 1996-03-27 | 2001-07-03 | The Regents Of The University Of California | Cryptopain vaccines, antibodies, proteins, peptides, DNA and RNA for prophylaxis, treatment and diagnosis and for detection of cryptosporidium species |
| JP3520089B2 (ja) * | 1993-12-22 | 2004-04-19 | アサヒビール株式会社 | 新規な組換えDerlアレルゲン物質、そのプロ体及びこれらの産生方法 |
| ATE207617T1 (de) * | 1995-03-24 | 2001-11-15 | Vorwerk Co Interholding | Verfahren zur untersuchung von hausstaub |
| JP3316535B2 (ja) * | 1995-03-28 | 2002-08-19 | アサヒビール株式会社 | ダニアレルゲンの改変体およびその製造法 |
| US6737406B1 (en) | 1996-03-21 | 2004-05-18 | Circassia, Ltd. | Cryptic peptides and method for their identification |
| EP1027435A2 (de) * | 1997-10-02 | 2000-08-16 | Max-Planck-Gesellschaft Zur Förderung Der Wissenschaften E.V. | Nukleinsäuremolekül kodierend für ein (poly)peptid, das in mutierter form mit autoimmuner polyendokrinopather candidose ektodermaler dystrophy (apedec) cosegregiert |
| GB9724531D0 (en) * | 1997-11-19 | 1998-01-21 | Smithkline Biolog | Novel compounds |
| US6455686B1 (en) * | 1998-04-17 | 2002-09-24 | Heska Corporation | Dermatophagoides nucleic acid molecules, proteins and uses thereof |
| US7128921B1 (en) * | 1998-04-17 | 2006-10-31 | Heska Corporation | Dermatophagoides proteins and fragments thereof |
| WO2001029078A2 (en) * | 1999-10-15 | 2001-04-26 | Heska Corporation | Method for production and use of mite group 1 proteins |
| WO2001077353A2 (en) * | 2000-04-05 | 2001-10-18 | Syngenta Participations Ag | Expression of pollen allergens in plastids |
| GB0014288D0 (en) * | 2000-06-10 | 2000-08-02 | Smithkline Beecham Biolog | Vaccine |
| US20020168782A1 (en) * | 2001-01-03 | 2002-11-14 | Mccall Catherine A. | Detection of allergen-specific IgE |
| FR2822709B1 (fr) * | 2001-03-30 | 2007-01-19 | Antialis | Composition pharmaceutique anti-allergique comprenant au moins un allergene et au moins un compose antihistaminique |
| US7927600B2 (en) * | 2001-03-30 | 2011-04-19 | Emile Loria | Anti-allergic pharmaceutical composition containing at least one allergen and at least one antihistamine compound |
| GB0120150D0 (en) * | 2001-08-17 | 2001-10-10 | Glaxosmithkline Biolog Sa | Novel compounds |
| AU2003246586A1 (en) * | 2002-07-10 | 2004-02-02 | Merck Patent Gmbh | Variants of the house dust mite allergen der f2 |
| US20060251667A1 (en) * | 2002-08-29 | 2006-11-09 | Chua Kaw Y | Recombinant nucleic acid useful for inducing protective immune response against allergens |
| EP1756275A1 (de) * | 2004-04-23 | 2007-02-28 | Novozymes A/S | Verfahren zur gewinnung reifer protease durch enzymatische verdauung |
| AT501101B1 (de) * | 2004-12-02 | 2008-01-15 | Biomay Ag | Protein-allergen-derivat |
| US7334521B2 (en) * | 2005-02-25 | 2008-02-26 | Cosco Industries, Inc. | Hand held two-ended ink stamper |
| US20070238750A1 (en) * | 2006-04-07 | 2007-10-11 | Michalis Nicolaou | Pure isomers of tritoqualine |
| ES2709176T3 (es) | 2006-08-11 | 2019-04-15 | Life Sciences Res Partners Vzw | Péptidos inmunogénicos y su uso en trastornos inmunitarios |
| EP2526938A3 (de) * | 2007-02-12 | 2013-06-12 | Mike Nicolaou | Hinstidindecarboxylasehemmern allein oder kombiniert mit einem Leukotriene Rezeptor Antagonist, einem Anti-H1 und/oder einem Anti-H2 zur Behandlung von COPD oder gastrointestinalen Erkrankungen |
| NZ583362A (en) * | 2007-08-15 | 2012-06-29 | Circassia Ltd | Peptide with reduced dimer formation |
| ES2637812T3 (es) | 2008-02-14 | 2017-10-17 | Life Sciences Research Partners Vzw | Inmunoterapia dirigida a patógenos intracelulares |
| EP2626081B1 (de) | 2008-02-14 | 2017-03-22 | Life Sciences Research Partners VZW | Immunogene Beeinflussung von Tumoren und Tumorzellen |
| CA2718994C (en) * | 2008-03-25 | 2017-06-13 | Bial Industrial Farmaceutica, S.A. | Hypoallergenic hybrid proteins of major group 1 and 2 mite allergens for use in the treatment of allergies |
| DE11787873T1 (de) | 2010-11-25 | 2013-12-12 | Imnate Sarl | Immugene Peptide zur Verwendung bei der Vorbeugung und/oder Behandlung von Infektionskrankheiten, Autoimmunerkrankungen, Immunreaktionen auf Allofaktoren, allergischen Erkrankungen, Tumoren, Transplantatabstossungen und Immunreaktionen auf virale Vektoren |
| GB201201511D0 (en) * | 2012-01-30 | 2012-03-14 | Univ Leuven Kath | Modified epitopes for boosting CD4+ T-cell responses |
| GB201309469D0 (en) | 2013-05-28 | 2013-07-10 | Imcyse Sa | Detection of CD4+ T lymphocytes |
| GB201418433D0 (en) | 2014-10-17 | 2014-12-03 | Imcyse Sa | Novel immunogenic peptides |
| US10729791B2 (en) | 2015-05-18 | 2020-08-04 | Imcyse Sa | Animal models for evaluating pharmaceutical compounds |
| CA2995771A1 (en) | 2015-09-25 | 2017-03-30 | Imcyse Sa | Improved methods and compounds for eliminating immune responses to therapeutic agents |
| BR112018071466A2 (pt) | 2016-04-19 | 2019-03-19 | Imcyse Sa | novos peptídeos de ligação a cd1d imunogênicos |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5026545A (en) * | 1984-09-17 | 1991-06-25 | Baxter International, Inc. | Treatment of allergy and composition therefor |
| JP2993967B2 (ja) * | 1987-06-17 | 1999-12-27 | インスティテュート・フォー・チャイルド・ヘルス・リサーチ | ダニアレルゲンのクローニング |
| JP2787162B2 (ja) * | 1989-08-24 | 1998-08-13 | フマキラー株式会社 | 精製ダニアレルゲン |
| US5433948A (en) * | 1990-02-13 | 1995-07-18 | Thomas; Wayne R. | Cloning and sequencing of allergens of dermatophagoides (house dust mite) |
| JP2596466B2 (ja) * | 1990-03-03 | 1997-04-02 | アサヒビール株式会社 | ダニの主要アレルゲンの還伝情報を有するdnaおよび該アレルゲンの製造方法 |
| JP3139777B2 (ja) * | 1990-08-27 | 2001-03-05 | フマキラー株式会社 | 組換えダニアレルゲン |
| DE69131131T2 (de) * | 1990-09-11 | 1999-10-14 | Institute For Child Health Research | Klonierung und sequenzierung von dermatophagoiden-antigenen (hausstaubmilben) |
| DE69233772D1 (de) * | 1991-10-16 | 2009-11-12 | Merck Patent Gmbh | T-zell epitopen von den wichtigsten allergene von dermatophagoides (hausmilbe) |
-
1992
- 1992-09-10 US US07/945,288 patent/US5433948A/en not_active Expired - Lifetime
-
1993
- 1993-09-10 ES ES93921462T patent/ES2112996T3/es not_active Expired - Lifetime
- 1993-09-10 AT AT93921462T patent/ATE163674T1/de active
- 1993-09-10 EP EP93921462A patent/EP0662129B1/de not_active Expired - Lifetime
- 1993-09-10 DE DE69317292T patent/DE69317292T2/de not_active Expired - Lifetime
- 1993-09-10 WO PCT/US1993/008518 patent/WO1994005790A1/en not_active Ceased
- 1993-09-10 NZ NZ256255A patent/NZ256255A/xx not_active IP Right Cessation
- 1993-09-10 AU AU48548/93A patent/AU680202B2/en not_active Expired
- 1993-09-10 DK DK93921462.3T patent/DK0662129T3/da active
- 1993-09-10 CA CA002144055A patent/CA2144055C/en not_active Expired - Lifetime
- 1993-09-10 JP JP50754294A patent/JP3487852B2/ja not_active Expired - Lifetime
-
1995
- 1995-06-05 US US08/462,831 patent/US5552142A/en not_active Expired - Lifetime
- 1995-06-05 US US08/461,809 patent/US5770202A/en not_active Expired - Lifetime
- 1995-06-05 US US08/461,441 patent/US5773002A/en not_active Expired - Lifetime
-
1998
- 1998-04-23 GR GR980400899T patent/GR3026711T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AU680202B2 (en) | 1997-07-24 |
| CA2144055A1 (en) | 1994-03-17 |
| US5770202A (en) | 1998-06-23 |
| US5433948A (en) | 1995-07-18 |
| DK0662129T3 (da) | 1998-03-30 |
| GR3026711T3 (en) | 1998-07-31 |
| US5552142A (en) | 1996-09-03 |
| DE69317292D1 (de) | 1998-04-09 |
| DE69317292T2 (de) | 1998-06-18 |
| WO1994005790A1 (en) | 1994-03-17 |
| CA2144055C (en) | 1999-11-02 |
| EP0662129A1 (de) | 1995-07-12 |
| US5773002A (en) | 1998-06-30 |
| EP0662129B1 (de) | 1998-03-04 |
| AU4854893A (en) | 1994-03-29 |
| ES2112996T3 (es) | 1998-04-16 |
| NZ256255A (en) | 1999-03-29 |
| JP3487852B2 (ja) | 2004-01-19 |
| JPH08504179A (ja) | 1996-05-07 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |