ATE164515T1 - Herstellung von liposomen und verfahren zur substanzverkapselung - Google Patents

Herstellung von liposomen und verfahren zur substanzverkapselung

Info

Publication number
ATE164515T1
ATE164515T1 AT95900452T AT95900452T ATE164515T1 AT E164515 T1 ATE164515 T1 AT E164515T1 AT 95900452 T AT95900452 T AT 95900452T AT 95900452 T AT95900452 T AT 95900452T AT E164515 T1 ATE164515 T1 AT E164515T1
Authority
AT
Austria
Prior art keywords
liposomes
lipid powder
liposome dispersion
dehydration
formation
Prior art date
Application number
AT95900452T
Other languages
English (en)
Inventor
David Sammuel Collins
Original Assignee
Amgen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Amgen Inc filed Critical Amgen Inc
Application granted granted Critical
Publication of ATE164515T1 publication Critical patent/ATE164515T1/de

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/127Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1277Preparation processes; Proliposomes
    • A61K9/1278Post-loading, e.g. by ion or pH gradient
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/127Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1277Preparation processes; Proliposomes

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Dispersion Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT95900452T 1993-11-05 1994-11-03 Herstellung von liposomen und verfahren zur substanzverkapselung ATE164515T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US14809993A 1993-11-05 1993-11-05

Publications (1)

Publication Number Publication Date
ATE164515T1 true ATE164515T1 (de) 1998-04-15

Family

ID=22524272

Family Applications (1)

Application Number Title Priority Date Filing Date
AT95900452T ATE164515T1 (de) 1993-11-05 1994-11-03 Herstellung von liposomen und verfahren zur substanzverkapselung

Country Status (10)

Country Link
US (2) US5567433A (de)
EP (1) EP0678017B1 (de)
JP (1) JPH08505882A (de)
AT (1) ATE164515T1 (de)
AU (1) AU683957B2 (de)
CA (1) CA2153251C (de)
DE (1) DE69409361T2 (de)
DK (1) DK0678017T3 (de)
ES (1) ES2115343T3 (de)
WO (1) WO1995012387A1 (de)

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WO2015166986A1 (ja) * 2014-04-30 2015-11-05 富士フイルム株式会社 リポソーム組成物及びその製造方法
LT3466432T (lt) 2014-05-15 2020-12-28 Insmed Incorporated Būdai, skirti plaučių netuberkuliozinėms mikobakterinėms infekcijoms gydyti
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US12151024B2 (en) 2021-01-22 2024-11-26 Pacira Pharmaceuticals, Inc. Manufacturing of bupivacaine multivesicular liposomes
US11033495B1 (en) 2021-01-22 2021-06-15 Pacira Pharmaceuticals, Inc. Manufacturing of bupivacaine multivesicular liposomes
US11357727B1 (en) 2021-01-22 2022-06-14 Pacira Pharmaceuticals, Inc. Manufacturing of bupivacaine multivesicular liposomes
US11278494B1 (en) 2021-01-22 2022-03-22 Pacira Pharmaceuticals, Inc. Manufacturing of bupivacaine multivesicular liposomes
EP4415713A4 (de) 2021-10-14 2025-08-06 Pacira Pharmaceuticals Inc Bupivacain-multivesikuläre liposomformulierungen und verwendungen davon
CN114916651B (zh) * 2022-05-19 2024-03-29 成都科建生物医药有限公司 一种芥末精油脂质体及其制备方法与应用
US20250319198A1 (en) * 2024-04-16 2025-10-16 Esm Technologies, Llc Method of preparing stable, high-load, water-dispersible liposomal compositions that incorporate water-insoluble therapeutics
US12251472B1 (en) 2024-05-20 2025-03-18 Pacira Pharmaceuticals, Inc. Manufacturing of bupivacaine multivesicular liposomes
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Also Published As

Publication number Publication date
CA2153251A1 (en) 1995-05-11
DE69409361D1 (de) 1998-05-07
DE69409361T2 (de) 1998-11-12
US6355267B1 (en) 2002-03-12
WO1995012387A1 (en) 1995-05-11
ES2115343T3 (es) 1998-06-16
EP0678017B1 (de) 1998-04-01
EP0678017A1 (de) 1995-10-25
CA2153251C (en) 1998-09-01
AU8127394A (en) 1995-05-23
JPH08505882A (ja) 1996-06-25
AU683957B2 (en) 1997-11-27
DK0678017T3 (da) 1998-10-19
US5567433A (en) 1996-10-22

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee