ATE167056T1 - Verwendung von ester von acyl-l-carnitin mit gammahydroxybuttersäure zur behandlung von alkoholismus - Google Patents

Verwendung von ester von acyl-l-carnitin mit gammahydroxybuttersäure zur behandlung von alkoholismus

Info

Publication number: ATE167056T1
Authority: AT; Austria
Prior art keywords: acyl; acid; carnitine; gammahydroxybututric; ester
Prior art date: 1993-03-26

Application number

AT94830122T

Other languages

English (en)

Inventor

Giovanni Scapagnini

Claudio Cavazza

Original Assignee

Sigma Tau Ind Farmaceuti

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1993-03-26

Filing date

1994-03-21

Publication date

1998-06-15

1994-03-21 Application filed by Sigma Tau Ind Farmaceuti filed Critical Sigma Tau Ind Farmaceuti

1998-06-15 Application granted granted Critical

1998-06-15 Publication of ATE167056T1 publication Critical patent/ATE167056T1/de

Links

239000002253 acid Substances 0.000 title abstract 2
208000007848 Alcoholism Diseases 0.000 title 1
201000007930 alcohol dependence Diseases 0.000 title 1
-1 acyl L-carnitine esters Chemical class 0.000 abstract 4
SJZRECIVHVDYJC-UHFFFAOYSA-N 4-hydroxybutyric acid Chemical compound OCCCC(O)=O SJZRECIVHVDYJC-UHFFFAOYSA-N 0.000 abstract 1
LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 1
208000007271 Substance Withdrawal Syndrome Diseases 0.000 abstract 1
125000002777 acetyl group Chemical group [H]C([H])([H])C(*)=O 0.000 abstract 1
125000002252 acyl group Chemical group 0.000 abstract 1
150000001450 anions Chemical class 0.000 abstract 1
125000004432 carbon atom Chemical group C* 0.000 abstract 1
235000019788 craving Nutrition 0.000 abstract 1
239000003814 drug Substances 0.000 abstract 1
229940079593 drug Drugs 0.000 abstract 1
125000001501 propionyl group Chemical group O=C([*])C([H])([H])C([H])([H])[H] 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/205—Amine addition salts of organic acids; Inner quaternary ammonium salts, e.g. betaine, carnitine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Epidemiology (AREA)
Psychiatry (AREA)
Neurosurgery (AREA)
Emergency Medicine (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Addiction (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Enzymes And Modification Thereof (AREA)

AT94830122T 1993-03-26 1994-03-21 Verwendung von ester von acyl-l-carnitin mit gammahydroxybuttersäure zur behandlung von alkoholismus ATE167056T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
ITRM930191A IT1261432B (it)	1993-03-26	1993-03-26	Uso di acil l- carnitina gammaidrossibutirrato per il trattamento dell'alcolismo.

Publications (1)

Publication Number	Publication Date
ATE167056T1 true ATE167056T1 (de)	1998-06-15

Family

ID=11401655

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT94830122T ATE167056T1 (de)	1993-03-26	1994-03-21	Verwendung von ester von acyl-l-carnitin mit gammahydroxybuttersäure zur behandlung von alkoholismus

Country Status (8)

Country	Link
EP (1)	EP0616805B1 (de)
JP (1)	JPH06321875A (de)
AT (1)	ATE167056T1 (de)
DE (1)	DE69410866T2 (de)
DK (1)	DK0616805T3 (de)
ES (1)	ES2118357T3 (de)
HK (1)	HK1009326A1 (de)
IT (1)	IT1261432B (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ES2150671T3 (es) *	1995-04-21	2000-12-01	Neurosearch As	Compuesto de bencimidazol y su utilizacion como moduladores del complejo de receptores gaba-a.

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IT1217783B (it) *	1988-06-03	1990-03-30	Farmaceutico Ct S R L Lab	Impiego di salo dell,acido gamma idrossi butirrico per la preparazione di composizioni farmaceutiche adatta ad essereimpiegate nella terapia dell,alcolismo e composizioni relative
IT1240760B (it) *	1990-02-12	1993-12-17	Sigma Tau Ind Farmaceuti	Esteri di acil-l-carnitine con l'acido gamma-idrossibutirrico e composizioni farmaceutiche che li contengono per l'inibizione della degenerazione neuronale e nel trattamento del coma.
IT1248321B (it) *	1991-05-15	1995-01-05	Sigma Tau Ind Farmaceuti	Uso di esteri di acil l-carnitine con l'acido gamma-idrossibutirrico per produrre composizioni farmaceutiche per il trattamento di epatopatie

1993
- 1993-03-26 IT ITRM930191A patent/IT1261432B/it active IP Right Grant
1994
- 1994-03-21 ES ES94830122T patent/ES2118357T3/es not_active Expired - Lifetime
- 1994-03-21 DE DE69410866T patent/DE69410866T2/de not_active Expired - Fee Related
- 1994-03-21 AT AT94830122T patent/ATE167056T1/de not_active IP Right Cessation
- 1994-03-21 EP EP94830122A patent/EP0616805B1/de not_active Expired - Lifetime
- 1994-03-21 DK DK94830122T patent/DK0616805T3/da active
- 1994-03-25 JP JP6055625A patent/JPH06321875A/ja active Pending
1998
- 1998-08-15 HK HK98109956A patent/HK1009326A1/en not_active IP Right Cessation

Also Published As

Publication number	Publication date
DE69410866T2 (de)	1998-10-15
IT1261432B (it)	1996-05-23
ES2118357T3 (es)	1998-09-16
HK1009326A1 (en)	1999-05-28
DK0616805T3 (da)	1999-02-01
EP0616805A1 (de)	1994-09-28
JPH06321875A (ja)	1994-11-22
EP0616805B1 (de)	1998-06-10
DE69410866D1 (de)	1998-07-16
ITRM930191A1 (it)	1994-09-26
ITRM930191A0 (it)	1993-03-26

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Legal Events

Date	Code	Title	Description
1998-12-15	UEP	Publication of translation of european patent specification
2006-12-15	REN	Ceased due to non-payment of the annual fee