ATE175205T1 - Neue urethan enthaltende aminosteroid verbindungen - Google Patents

Neue urethan enthaltende aminosteroid verbindungen

Info

Publication number: ATE175205T1
Authority: AT; Austria
Prior art keywords: urethane containing; new urethane; aminosteroid compounds; compounds; containing aminosteroid
Prior art date: 1993-09-24

Application number

AT94929872T

Other languages

English (en)

Inventor

Chia-Nien Yu

Gilles Yves Genain

Rachel Boujo

Original Assignee

Procter & Gamble

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1993-09-24

Filing date

1994-09-23

Publication date

1999-01-15

1994-09-23 Application filed by Procter & Gamble filed Critical Procter & Gamble

1999-01-15 Application granted granted Critical

1999-01-15 Publication of ATE175205T1 publication Critical patent/ATE175205T1/de

Links

JOYRKODLDBILNP-UHFFFAOYSA-N Ethyl urethane Chemical compound CCOC(N)=O JOYRKODLDBILNP-UHFFFAOYSA-N 0.000 title abstract 2
NDDAQHROMJDMKS-XFYXLWKMSA-N [(2s,3s,5s,8r,9s,10s,13s,14s)-2-hydroxy-10,13-dimethyl-17-oxo-1,2,3,4,5,6,7,8,9,11,12,14,15,16-tetradecahydrocyclopenta[a]phenanthren-3-yl]azanium;chloride Chemical class Cl.C1[C@H](N)[C@@H](O)C[C@]2(C)[C@H]3CC[C@](C)(C(CC4)=O)[C@@H]4[C@@H]3CC[C@H]21 NDDAQHROMJDMKS-XFYXLWKMSA-N 0.000 title 1
206010007559 Cardiac failure congestive Diseases 0.000 abstract 1
206010019280 Heart failures Diseases 0.000 abstract 1
-1 amino steroids Chemical class 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
239000000203 mixture Substances 0.000 abstract 1
239000008194 pharmaceutical composition Substances 0.000 abstract 1
239000000126 substance Substances 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C07J41/0005—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring the nitrogen atom being directly linked to the cyclopenta(a)hydro phenanthrene skeleton
- C07J41/0011—Unsubstituted amino radicals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
- C07J41/0038—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 with an androstane skeleton, including 18- or 19-substituted derivatives, 18-nor derivatives and also derivatives where position 17-beta is substituted by a carbon atom not directly bonded to a further carbon atom and not being part of an amide group
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
- C07J41/0088—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 containing unsubstituted amino radicals
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J43/00—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
- C07J43/003—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton not condensed

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Veterinary Medicine (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Chemical Kinetics & Catalysis (AREA)
Heart & Thoracic Surgery (AREA)
Engineering & Computer Science (AREA)
Cardiology (AREA)
Epidemiology (AREA)
Steroid Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

AT94929872T 1993-09-24 1994-09-23 Neue urethan enthaltende aminosteroid verbindungen ATE175205T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US08/126,293 US5922703A (en)	1993-09-24	1993-09-24	Urethane-containing aminosteroid compounds

Publications (1)

Publication Number	Publication Date
ATE175205T1 true ATE175205T1 (de)	1999-01-15

Family

ID=22424049

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT94929872T ATE175205T1 (de)	1993-09-24	1994-09-23	Neue urethan enthaltende aminosteroid verbindungen

Country Status (17)

Country	Link
US (1)	US5922703A (de)
EP (1)	EP0720617B1 (de)
JP (1)	JPH09502984A (de)
KR (1)	KR960704913A (de)
CN (1)	CN1135221A (de)
AT (1)	ATE175205T1 (de)
AU (1)	AU690926B2 (de)
BR (1)	BR9407654A (de)
CA (1)	CA2172495A1 (de)
CZ (1)	CZ86296A3 (de)
DE (1)	DE69415682T2 (de)
DK (1)	DK0720617T3 (de)
ES (1)	ES2126155T3 (de)
HU (1)	HUT74169A (de)
NO (1)	NO307757B1 (de)
PL (1)	PL313622A1 (de)
WO (1)	WO1995008559A1 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
RU2153503C2 (ru) *	1993-09-24	2000-07-27	Зе Проктер энд Гэмбл Компани	Олигосахаридсодержащие 14-аминостероиды, способ их получения, фармацевтическая композиция, способ лечения, способ введения аминогруппы
US6339716B1 (en) *	1999-09-24	2002-01-15	Bioenergy Inc.	Method for determining viability of a myocardial segment
CA2669753C (en)	1999-09-30	2012-06-26	Hollis-Eden Pharmaceuticals, Inc.	Therapeutic treatment of androgen receptor driven conditions
US6703370B1 (en)	1999-10-27	2004-03-09	Bioenergy, Inc.	Use of ribose to treat fibromyalgia
CN103980338B (zh)	2010-01-15	2017-04-26	苏州润新生物科技有限公司	蟾蜍灵衍生物、其药物组合物及用途
CN102656179B (zh)	2010-08-28	2015-07-29	苏州润新生物科技有限公司	蟾蜍灵衍生物、其药物组合物及用途
EP3453714B1 (de) *	2011-02-02	2020-11-04	Suzhou Neupharma Co., Ltd	Cardenolid- und bufadienolid- 3-carbonate and 3-carbamate derivative zur behandlung von krebs sowie zusammensetzungen davon
EP2852285B1 (de)	2012-04-29	2018-08-08	Neupharma, Inc.	Bufadienolidverbindungen mit einer 3-heterozyklischen amingruppe zur behandlung von krebs
US12030912B2 (en) *	2020-05-15	2024-07-09	Brigham Young University	Cationic steroidal antimicrobial compounds with urethane linkages

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4273866A (en) *	1979-02-05	1981-06-16	Abbott Laboratories	Ligand analog-irreversible enzyme inhibitor conjugates and methods for use
FR2464270A1 (fr) *	1979-08-31	1981-03-06	Nativelle Sa Ets	Nouveaux derives d'amino-14 steroides, et procede pour leur preparation
DD154899A1 (de) *	1980-12-01	1982-04-28	Rudolf Megges	Verfahren zur herstellung von cardenolid-und bufadienolid-14 beta-o-urethanen
ES524614A0 (es) *	1982-08-12	1984-05-01	Nativelle Sa Ets	Procedimiento de preparacion de nuevos amino-14 esteroides.
NZ205293A (en) *	1982-08-20	1986-12-05	Nativelle Sa Ets	14-aminosteroids and pharmaceutical compositions
ES8404694A1 (es) *	1982-08-20	1984-05-01	Nativelle Sa Ets	Procedimiento de preparacion de nuevos derivos de amino-14 esteroides
DD256134A1 (de) *	1985-06-06	1988-04-27	Akad Wissenschaften Ddr	Verfahren zur herstellung von derivaten von cardenoliden und cardenolidanalogen verbindungen
US5175281A (en) *	1985-09-12	1992-12-29	The Upjohn Company	Pharmaceutically active pyrimidinylpiperazinylsterioids
GB8600490D0 (en) *	1986-01-09	1986-02-12	Erba Farmitalia	Aminoglycoside norcholanic acid lactams
GB8600489D0 (en) *	1986-01-09	1986-02-12	Erba Farmitalia	Aminoglycoside steroids
FR2621316B1 (fr) *	1987-10-02	1991-06-21	Nativelle Sa Ets	Nouveaux esters d'acide androstane 17-carboxylique, procede pour leur preparation, et medicament les contenant
US5144017A (en) *	1988-07-13	1992-09-01	University Of Manitoba	Compounds that bind to digitalis receptor
FR2642973A1 (fr) *	1989-02-03	1990-08-17	Cote Ivoire Ministere Rech Sc	Composition medicamenteuse renfermant comme principe actif un derive glucidique dioxymethyle de la strophanthidine
AU7794391A (en) *	1990-05-07	1991-11-27	Board Of Regents Of The University Of Washington, The	Novel steroid glycosides useful in the early detection of hypertension
JPH0429089A (ja) *	1990-05-25	1992-01-31	Toshiba Corp	燃料集合体
RU2153503C2 (ru) *	1993-09-24	2000-07-27	Зе Проктер энд Гэмбл Компани	Олигосахаридсодержащие 14-аминостероиды, способ их получения, фармацевтическая композиция, способ лечения, способ введения аминогруппы
HUT74610A (en) *	1993-09-24	1997-01-28	Procter & Gamble	Novel deoxy and oxygen-substituted sugar-containing 14-aminosteroid compounds, pharmaceutical compositions containing them, process for producing the same and intermediate

1993
- 1993-09-24 US US08/126,293 patent/US5922703A/en not_active Expired - Fee Related
1994
- 1994-09-23 CZ CZ96862A patent/CZ86296A3/cs unknown
- 1994-09-23 PL PL94313622A patent/PL313622A1/xx unknown
- 1994-09-23 HU HU9600736A patent/HUT74169A/hu unknown
- 1994-09-23 KR KR1019960701528A patent/KR960704913A/ko not_active Withdrawn
- 1994-09-23 AT AT94929872T patent/ATE175205T1/de not_active IP Right Cessation
- 1994-09-23 WO PCT/US1994/010780 patent/WO1995008559A1/en not_active Ceased
- 1994-09-23 JP JP7509954A patent/JPH09502984A/ja active Pending
- 1994-09-23 BR BR9407654A patent/BR9407654A/pt not_active Application Discontinuation
- 1994-09-23 ES ES94929872T patent/ES2126155T3/es not_active Expired - Lifetime
- 1994-09-23 EP EP94929872A patent/EP0720617B1/de not_active Expired - Lifetime
- 1994-09-23 DE DE69415682T patent/DE69415682T2/de not_active Expired - Fee Related
- 1994-09-23 CA CA002172495A patent/CA2172495A1/en not_active Abandoned
- 1994-09-23 DK DK94929872T patent/DK0720617T3/da active
- 1994-09-23 AU AU78779/94A patent/AU690926B2/en not_active Ceased
- 1994-09-23 CN CN94194213A patent/CN1135221A/zh active Pending
1996
- 1996-03-22 NO NO961168A patent/NO307757B1/no not_active IP Right Cessation

Also Published As

Publication number	Publication date
CA2172495A1 (en)	1995-03-30
PL313622A1 (en)	1996-07-08
NO961168D0 (no)	1996-03-22
DE69415682T2 (de)	1999-07-22
EP0720617A1 (de)	1996-07-10
JPH09502984A (ja)	1997-03-25
EP0720617B1 (de)	1998-12-30
AU690926B2 (en)	1998-05-07
AU7877994A (en)	1995-04-10
CN1135221A (zh)	1996-11-06
BR9407654A (pt)	1997-01-28
CZ86296A3 (en)	1996-12-11
NO307757B1 (no)	2000-05-22
HU9600736D0 (en)	1996-05-28
ES2126155T3 (es)	1999-03-16
HUT74169A (en)	1996-11-28
WO1995008559A1 (en)	1995-03-30
NO961168L (no)	1996-05-23
DE69415682D1 (de)	1999-02-11
DK0720617T3 (da)	1999-08-30
US5922703A (en)	1999-07-13
KR960704913A (ko)	1996-10-09

Legal Events

Date	Code	Title	Description
1999-09-15	UEP	Publication of translation of european patent specification
2001-06-15	REN	Ceased due to non-payment of the annual fee

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ATE218142T1 (de)	2002-06-15	Nitratester von corticoid verbindungen und die therapeutische verwendungen davon
PT722319E (pt)	2002-10-31	Derivados de antraciclinona e a sua utilizacao no tratamento da amiloidose
ATE175205T1 (de)	1999-01-15	Neue urethan enthaltende aminosteroid verbindungen
DE59610251D1 (de)	2003-04-24	Konjugat, umfassend einen wirkstoff, ein polypeptid und einen polyether
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