NO961168L - Nye uretanholdige aminosteroid forbindelser - Google Patents
Nye uretanholdige aminosteroid forbindelserInfo
- Publication number
- NO961168L NO961168L NO961168A NO961168A NO961168L NO 961168 L NO961168 L NO 961168L NO 961168 A NO961168 A NO 961168A NO 961168 A NO961168 A NO 961168A NO 961168 L NO961168 L NO 961168L
- Authority
- NO
- Norway
- Prior art keywords
- new urethane
- aminosteroid compounds
- compounds
- urethane
- containing aminosteroid
- Prior art date
Links
- JOYRKODLDBILNP-UHFFFAOYSA-N Ethyl urethane Chemical compound CCOC(N)=O JOYRKODLDBILNP-UHFFFAOYSA-N 0.000 title abstract 2
- NDDAQHROMJDMKS-XFYXLWKMSA-N [(2s,3s,5s,8r,9s,10s,13s,14s)-2-hydroxy-10,13-dimethyl-17-oxo-1,2,3,4,5,6,7,8,9,11,12,14,15,16-tetradecahydrocyclopenta[a]phenanthren-3-yl]azanium;chloride Chemical class Cl.C1[C@H](N)[C@@H](O)C[C@]2(C)[C@H]3CC[C@](C)(C(CC4)=O)[C@@H]4[C@@H]3CC[C@H]21 NDDAQHROMJDMKS-XFYXLWKMSA-N 0.000 title 1
- 206010007559 Cardiac failure congestive Diseases 0.000 abstract 1
- 206010019280 Heart failures Diseases 0.000 abstract 1
- -1 amino steroids Chemical class 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C07J41/0005—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring the nitrogen atom being directly linked to the cyclopenta(a)hydro phenanthrene skeleton
- C07J41/0011—Unsubstituted amino radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
- C07J41/0038—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 with an androstane skeleton, including 18- or 19-substituted derivatives, 18-nor derivatives and also derivatives where position 17-beta is substituted by a carbon atom not directly bonded to a further carbon atom and not being part of an amide group
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
- C07J41/0088—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 containing unsubstituted amino radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J43/00—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
- C07J43/003—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton not condensed
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Heart & Thoracic Surgery (AREA)
- Engineering & Computer Science (AREA)
- Cardiology (AREA)
- Epidemiology (AREA)
- Steroid Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/126,293 US5922703A (en) | 1993-09-24 | 1993-09-24 | Urethane-containing aminosteroid compounds |
| PCT/US1994/010780 WO1995008559A1 (en) | 1993-09-24 | 1994-09-23 | Novel urethane-containing aminosteroid compounds |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NO961168D0 NO961168D0 (no) | 1996-03-22 |
| NO961168L true NO961168L (no) | 1996-05-23 |
| NO307757B1 NO307757B1 (no) | 2000-05-22 |
Family
ID=22424049
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO961168A NO307757B1 (no) | 1993-09-24 | 1996-03-22 | Uretanholdige aminosteroidforbindelser, farmasøytisk preparat samt anvendelse |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US5922703A (no) |
| EP (1) | EP0720617B1 (no) |
| JP (1) | JPH09502984A (no) |
| KR (1) | KR960704913A (no) |
| CN (1) | CN1135221A (no) |
| AT (1) | ATE175205T1 (no) |
| AU (1) | AU690926B2 (no) |
| BR (1) | BR9407654A (no) |
| CA (1) | CA2172495A1 (no) |
| CZ (1) | CZ86296A3 (no) |
| DE (1) | DE69415682T2 (no) |
| DK (1) | DK0720617T3 (no) |
| ES (1) | ES2126155T3 (no) |
| HU (1) | HUT74169A (no) |
| NO (1) | NO307757B1 (no) |
| PL (1) | PL313622A1 (no) |
| WO (1) | WO1995008559A1 (no) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2146665T3 (es) * | 1993-09-24 | 2000-08-16 | Procter & Gamble | Nuevos compuestos 14-aminoesteroides que contienen oligosacaridos y nuevo procedimiento en quimica de aminoesteroides diastereoselectivo. |
| US6339716B1 (en) * | 1999-09-24 | 2002-01-15 | Bioenergy Inc. | Method for determining viability of a myocardial segment |
| AU7736300A (en) | 1999-09-30 | 2001-04-30 | Hollis-Eden Pharmaceuticals, Inc. | Therapeutic treatment of androgen receptor driven conditions |
| US6703370B1 (en) | 1999-10-27 | 2004-03-09 | Bioenergy, Inc. | Use of ribose to treat fibromyalgia |
| ES2654584T3 (es) | 2010-01-15 | 2018-02-14 | Suzhou Neupharma Co., Ltd | Ciertas entidades químicas, composiciones y métodos |
| US9018197B2 (en) | 2010-08-28 | 2015-04-28 | Suzhou Neupharma Co. Ltd. | Tetradecahydro-1H-cyclopenta[a]phenanthrene compounds, compositions, and related methods of use |
| EP3453714B1 (en) * | 2011-02-02 | 2020-11-04 | Suzhou Neupharma Co., Ltd | Cardenolide and bufadienolide 3-carbonate and 3-carbamate derivatives for the treatment of cancer and compositions thereof |
| EP3453713B1 (en) | 2012-04-29 | 2021-09-08 | Neupharma, Inc. | Bufadienolide compounds substituted in position 3 by an amine group for use in the treatment of cancer |
| US12030912B2 (en) * | 2020-05-15 | 2024-07-09 | Brigham Young University | Cationic steroidal antimicrobial compounds with urethane linkages |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4273866A (en) * | 1979-02-05 | 1981-06-16 | Abbott Laboratories | Ligand analog-irreversible enzyme inhibitor conjugates and methods for use |
| FR2464270A1 (fr) * | 1979-08-31 | 1981-03-06 | Nativelle Sa Ets | Nouveaux derives d'amino-14 steroides, et procede pour leur preparation |
| DD154899A1 (de) * | 1980-12-01 | 1982-04-28 | Rudolf Megges | Verfahren zur herstellung von cardenolid-und bufadienolid-14 beta-o-urethanen |
| ES8404693A1 (es) * | 1982-08-12 | 1984-05-01 | Nativelle Sa Ets | Procedimiento de preparacion de nuevos amino-14 esteroides. |
| ES8404694A1 (es) * | 1982-08-20 | 1984-05-01 | Nativelle Sa Ets | Procedimiento de preparacion de nuevos derivos de amino-14 esteroides |
| NZ205293A (en) * | 1982-08-20 | 1986-12-05 | Nativelle Sa Ets | 14-aminosteroids and pharmaceutical compositions |
| DD256134A1 (de) * | 1985-06-06 | 1988-04-27 | Akad Wissenschaften Ddr | Verfahren zur herstellung von derivaten von cardenoliden und cardenolidanalogen verbindungen |
| US5175281A (en) * | 1985-09-12 | 1992-12-29 | The Upjohn Company | Pharmaceutically active pyrimidinylpiperazinylsterioids |
| GB8600490D0 (en) * | 1986-01-09 | 1986-02-12 | Erba Farmitalia | Aminoglycoside norcholanic acid lactams |
| FR2621316B1 (fr) * | 1987-10-02 | 1991-06-21 | Nativelle Sa Ets | Nouveaux esters d'acide androstane 17-carboxylique, procede pour leur preparation, et medicament les contenant |
| US5144017A (en) * | 1988-07-13 | 1992-09-01 | University Of Manitoba | Compounds that bind to digitalis receptor |
| FR2642973A1 (fr) * | 1989-02-03 | 1990-08-17 | Cote Ivoire Ministere Rech Sc | Composition medicamenteuse renfermant comme principe actif un derive glucidique dioxymethyle de la strophanthidine |
| EP0530224A1 (en) * | 1990-05-07 | 1993-03-10 | The Board Of Regents Of The University Of Washington | Novel steroid glycosides useful in the early detection of hypertension |
| JPH0429089A (ja) * | 1990-05-25 | 1992-01-31 | Toshiba Corp | 燃料集合体 |
| CZ86796A3 (en) * | 1993-09-24 | 1996-10-16 | Procter & Gamble | Novel deoxy and on oxygen substituted sugar derivatives of aminosteroidal compounds |
| ES2146665T3 (es) * | 1993-09-24 | 2000-08-16 | Procter & Gamble | Nuevos compuestos 14-aminoesteroides que contienen oligosacaridos y nuevo procedimiento en quimica de aminoesteroides diastereoselectivo. |
-
1993
- 1993-09-24 US US08/126,293 patent/US5922703A/en not_active Expired - Fee Related
-
1994
- 1994-09-23 PL PL94313622A patent/PL313622A1/xx unknown
- 1994-09-23 ES ES94929872T patent/ES2126155T3/es not_active Expired - Lifetime
- 1994-09-23 EP EP94929872A patent/EP0720617B1/en not_active Expired - Lifetime
- 1994-09-23 CZ CZ96862A patent/CZ86296A3/cs unknown
- 1994-09-23 AU AU78779/94A patent/AU690926B2/en not_active Ceased
- 1994-09-23 BR BR9407654A patent/BR9407654A/pt not_active Application Discontinuation
- 1994-09-23 HU HU9600736A patent/HUT74169A/hu unknown
- 1994-09-23 CN CN94194213A patent/CN1135221A/zh active Pending
- 1994-09-23 JP JP7509954A patent/JPH09502984A/ja active Pending
- 1994-09-23 DE DE69415682T patent/DE69415682T2/de not_active Expired - Fee Related
- 1994-09-23 CA CA002172495A patent/CA2172495A1/en not_active Abandoned
- 1994-09-23 KR KR1019960701528A patent/KR960704913A/ko not_active Withdrawn
- 1994-09-23 DK DK94929872T patent/DK0720617T3/da active
- 1994-09-23 AT AT94929872T patent/ATE175205T1/de not_active IP Right Cessation
- 1994-09-23 WO PCT/US1994/010780 patent/WO1995008559A1/en not_active Ceased
-
1996
- 1996-03-22 NO NO961168A patent/NO307757B1/no not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| BR9407654A (pt) | 1997-01-28 |
| US5922703A (en) | 1999-07-13 |
| NO961168D0 (no) | 1996-03-22 |
| AU690926B2 (en) | 1998-05-07 |
| HU9600736D0 (en) | 1996-05-28 |
| NO307757B1 (no) | 2000-05-22 |
| HUT74169A (en) | 1996-11-28 |
| JPH09502984A (ja) | 1997-03-25 |
| DE69415682D1 (de) | 1999-02-11 |
| DE69415682T2 (de) | 1999-07-22 |
| ES2126155T3 (es) | 1999-03-16 |
| WO1995008559A1 (en) | 1995-03-30 |
| EP0720617A1 (en) | 1996-07-10 |
| EP0720617B1 (en) | 1998-12-30 |
| KR960704913A (ko) | 1996-10-09 |
| AU7877994A (en) | 1995-04-10 |
| CN1135221A (zh) | 1996-11-06 |
| CA2172495A1 (en) | 1995-03-30 |
| CZ86296A3 (en) | 1996-12-11 |
| ATE175205T1 (de) | 1999-01-15 |
| DK0720617T3 (da) | 1999-08-30 |
| PL313622A1 (en) | 1996-07-08 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MM1K | Lapsed by not paying the annual fees |
Free format text: LAPSED IN MARCH 2001 |