ES2126155T3 - Nuevos compuestos aminoesteroidales que contienen uretano. - Google Patents

Nuevos compuestos aminoesteroidales que contienen uretano.

Info

Publication number
ES2126155T3
ES2126155T3 ES94929872T ES94929872T ES2126155T3 ES 2126155 T3 ES2126155 T3 ES 2126155T3 ES 94929872 T ES94929872 T ES 94929872T ES 94929872 T ES94929872 T ES 94929872T ES 2126155 T3 ES2126155 T3 ES 2126155T3
Authority
ES
Spain
Prior art keywords
containing urethane
compounds containing
sub
steroidal compounds
new amino
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES94929872T
Other languages
English (en)
Inventor
Chia-Nien Yu
Gilles Yves Genain
Rachel Boujo
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Procter and Gamble Co
Original Assignee
Procter and Gamble Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Procter and Gamble Co filed Critical Procter and Gamble Co
Application granted granted Critical
Publication of ES2126155T3 publication Critical patent/ES2126155T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J41/00Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J41/00Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0005Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring the nitrogen atom being directly linked to the cyclopenta(a)hydro phenanthrene skeleton
    • C07J41/0011Unsubstituted amino radicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J41/00Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0038Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 with an androstane skeleton, including 18- or 19-substituted derivatives, 18-nor derivatives and also derivatives where position 17-beta is substituted by a carbon atom not directly bonded to a further carbon atom and not being part of an amide group
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J41/00Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0088Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 containing unsubstituted amino radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J43/00Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J43/003Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton not condensed

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Engineering & Computer Science (AREA)
  • Cardiology (AREA)
  • Epidemiology (AREA)
  • Steroid Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

COMPUESTOS DE AMINOSTEROIDES QUE CONTIENEN URETANO Y LAS SALES ACIDAS O ESTERES FARMACEUTICAMENTE ACEPTABLES DE LOS MISMOS DE LA FORMULA GENERAL (I) EN LA QUE R{SUB,1}, R{SUB,2}, R{SUB,3}, R{SUB,4} Y R{SUB,14} SE DEFINEN EN LA DESCRIPCION, EN DONDE R{SUB,3} ES UN GRUPO QUE CONTIENE URETANO.
ES94929872T 1993-09-24 1994-09-23 Nuevos compuestos aminoesteroidales que contienen uretano. Expired - Lifetime ES2126155T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/126,293 US5922703A (en) 1993-09-24 1993-09-24 Urethane-containing aminosteroid compounds

Publications (1)

Publication Number Publication Date
ES2126155T3 true ES2126155T3 (es) 1999-03-16

Family

ID=22424049

Family Applications (1)

Application Number Title Priority Date Filing Date
ES94929872T Expired - Lifetime ES2126155T3 (es) 1993-09-24 1994-09-23 Nuevos compuestos aminoesteroidales que contienen uretano.

Country Status (17)

Country Link
US (1) US5922703A (es)
EP (1) EP0720617B1 (es)
JP (1) JPH09502984A (es)
KR (1) KR960704913A (es)
CN (1) CN1135221A (es)
AT (1) ATE175205T1 (es)
AU (1) AU690926B2 (es)
BR (1) BR9407654A (es)
CA (1) CA2172495A1 (es)
CZ (1) CZ86296A3 (es)
DE (1) DE69415682T2 (es)
DK (1) DK0720617T3 (es)
ES (1) ES2126155T3 (es)
HU (1) HUT74169A (es)
NO (1) NO307757B1 (es)
PL (1) PL313622A1 (es)
WO (1) WO1995008559A1 (es)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995008557A1 (en) * 1993-09-24 1995-03-30 The Procter & Gamble Company Novel oligosaccharide-containing 14-aminosteroid compounds and novel diastereoselective aminosteroid process chemistry
US6339716B1 (en) * 1999-09-24 2002-01-15 Bioenergy Inc. Method for determining viability of a myocardial segment
PT1955700E (pt) 1999-09-30 2011-05-04 Harbor Biosciences Inc Tratamento terap?utico de doen?as associadas ao receptor de androg?nios
US6703370B1 (en) 1999-10-27 2004-03-09 Bioenergy, Inc. Use of ribose to treat fibromyalgia
CN103980337B (zh) 2010-01-15 2016-08-24 苏州润新生物科技有限公司 蟾蜍灵衍生物、其药物组合物及用途
US9018197B2 (en) 2010-08-28 2015-04-28 Suzhou Neupharma Co. Ltd. Tetradecahydro-1H-cyclopenta[a]phenanthrene compounds, compositions, and related methods of use
CN103619865B (zh) 2011-02-02 2016-10-12 苏州润新生物科技有限公司 某些化学个体、组合物及方法
CN104427873B (zh) 2012-04-29 2018-11-06 润新生物公司 某些化学个体、组合物及方法
US12030912B2 (en) * 2020-05-15 2024-07-09 Brigham Young University Cationic steroidal antimicrobial compounds with urethane linkages

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4273866A (en) * 1979-02-05 1981-06-16 Abbott Laboratories Ligand analog-irreversible enzyme inhibitor conjugates and methods for use
FR2464270A1 (fr) * 1979-08-31 1981-03-06 Nativelle Sa Ets Nouveaux derives d'amino-14 steroides, et procede pour leur preparation
DD154899A1 (de) * 1980-12-01 1982-04-28 Rudolf Megges Verfahren zur herstellung von cardenolid-und bufadienolid-14 beta-o-urethanen
ES8404693A1 (es) * 1982-08-12 1984-05-01 Nativelle Sa Ets Procedimiento de preparacion de nuevos amino-14 esteroides.
ES8404694A1 (es) * 1982-08-20 1984-05-01 Nativelle Sa Ets Procedimiento de preparacion de nuevos derivos de amino-14 esteroides
NZ205293A (en) * 1982-08-20 1986-12-05 Nativelle Sa Ets 14-aminosteroids and pharmaceutical compositions
DD256134A1 (de) * 1985-06-06 1988-04-27 Akad Wissenschaften Ddr Verfahren zur herstellung von derivaten von cardenoliden und cardenolidanalogen verbindungen
US5175281A (en) * 1985-09-12 1992-12-29 The Upjohn Company Pharmaceutically active pyrimidinylpiperazinylsterioids
GB8600490D0 (en) * 1986-01-09 1986-02-12 Erba Farmitalia Aminoglycoside norcholanic acid lactams
FR2621316B1 (fr) * 1987-10-02 1991-06-21 Nativelle Sa Ets Nouveaux esters d'acide androstane 17-carboxylique, procede pour leur preparation, et medicament les contenant
US5144017A (en) * 1988-07-13 1992-09-01 University Of Manitoba Compounds that bind to digitalis receptor
FR2642973A1 (fr) * 1989-02-03 1990-08-17 Cote Ivoire Ministere Rech Sc Composition medicamenteuse renfermant comme principe actif un derive glucidique dioxymethyle de la strophanthidine
EP0530224A1 (en) * 1990-05-07 1993-03-10 The Board Of Regents Of The University Of Washington Novel steroid glycosides useful in the early detection of hypertension
JPH0429089A (ja) * 1990-05-25 1992-01-31 Toshiba Corp 燃料集合体
CZ86796A3 (en) * 1993-09-24 1996-10-16 Procter & Gamble Novel deoxy and on oxygen substituted sugar derivatives of aminosteroidal compounds
WO1995008557A1 (en) * 1993-09-24 1995-03-30 The Procter & Gamble Company Novel oligosaccharide-containing 14-aminosteroid compounds and novel diastereoselective aminosteroid process chemistry

Also Published As

Publication number Publication date
EP0720617A1 (en) 1996-07-10
ATE175205T1 (de) 1999-01-15
CN1135221A (zh) 1996-11-06
NO307757B1 (no) 2000-05-22
AU690926B2 (en) 1998-05-07
CA2172495A1 (en) 1995-03-30
HUT74169A (en) 1996-11-28
EP0720617B1 (en) 1998-12-30
KR960704913A (ko) 1996-10-09
PL313622A1 (en) 1996-07-08
DK0720617T3 (da) 1999-08-30
JPH09502984A (ja) 1997-03-25
HU9600736D0 (en) 1996-05-28
BR9407654A (pt) 1997-01-28
DE69415682T2 (de) 1999-07-22
WO1995008559A1 (en) 1995-03-30
US5922703A (en) 1999-07-13
NO961168L (no) 1996-05-23
NO961168D0 (no) 1996-03-22
DE69415682D1 (de) 1999-02-11
AU7877994A (en) 1995-04-10
CZ86296A3 (en) 1996-12-11

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