ATE180677T1 - Fullerene zusammensetzungen für m.r.i. - Google Patents

Fullerene zusammensetzungen für m.r.i.

Info

Publication number
ATE180677T1
ATE180677T1 AT92917886T AT92917886T ATE180677T1 AT E180677 T1 ATE180677 T1 AT E180677T1 AT 92917886 T AT92917886 T AT 92917886T AT 92917886 T AT92917886 T AT 92917886T AT E180677 T1 ATE180677 T1 AT E180677T1
Authority
AT
Austria
Prior art keywords
imaging
fluorine
compositions
carbon
carbon clusters
Prior art date
Application number
AT92917886T
Other languages
English (en)
Inventor
William L Neumann
William P Cacheris
Original Assignee
Mallinckrodt Medical Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mallinckrodt Medical Inc filed Critical Mallinckrodt Medical Inc
Application granted granted Critical
Publication of ATE180677T1 publication Critical patent/ATE180677T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/18—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes
    • A61K49/189—Host-guest complexes, e.g. cyclodextrins
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/24—Nuclear magnetic resonance, electron spin resonance or other spin effects or mass spectrometry

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nanotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Biophysics (AREA)
  • Medical Informatics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)
  • Dental Preparations (AREA)
  • Macromonomer-Based Addition Polymer (AREA)
  • Carbon And Carbon Compounds (AREA)
  • Compounds Of Iron (AREA)
  • Soft Magnetic Materials (AREA)
AT92917886T 1991-08-19 1992-07-30 Fullerene zusammensetzungen für m.r.i. ATE180677T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/746,836 US5248498A (en) 1991-08-19 1991-08-19 Fullerene compositions for magnetic resonance spectroscopy and imaging

Publications (1)

Publication Number Publication Date
ATE180677T1 true ATE180677T1 (de) 1999-06-15

Family

ID=25002556

Family Applications (1)

Application Number Title Priority Date Filing Date
AT92917886T ATE180677T1 (de) 1991-08-19 1992-07-30 Fullerene zusammensetzungen für m.r.i.

Country Status (8)

Country Link
US (1) US5248498A (de)
EP (1) EP0599946B1 (de)
JP (1) JPH06509802A (de)
AT (1) ATE180677T1 (de)
AU (1) AU657789B2 (de)
CA (1) CA2113996A1 (de)
DE (1) DE69229348T2 (de)
WO (1) WO1993003771A1 (de)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9203037D0 (en) * 1992-02-11 1992-03-25 Salutar Inc Contrast agents
US5468467A (en) * 1993-04-23 1995-11-21 Bracco International B.V. Methods for the in vivo measurement of the concentration of non-imaging nmr-detectable xenobiotic compounds
JPH0797340A (ja) * 1993-06-03 1995-04-11 Terumo Corp Ｍｒｉ造影剤組成物
CN1064777C (zh) * 1993-06-24 2001-04-18 卡耐基米龙大学 金属、合金或金属碳化物的纳米颗粒及其制备方法
US5456986A (en) * 1993-06-30 1995-10-10 Carnegie Mellon University Magnetic metal or metal carbide nanoparticles and a process for forming same
AU7960094A (en) * 1993-10-04 1995-05-01 Mallinckrodt Medical, Inc. Compositions and methods for magnetic resonance imaging, x-ray imaging and radiopharmaceuticals
WO1996024139A2 (en) 1995-01-23 1996-08-08 Schaefer Daniel R Trapping and storage of free thermal neutrons in fullerene molecules
US5660815A (en) * 1995-04-28 1997-08-26 Molecular Biosystems, Inc. Water soluble fluorinated fatty acid sulfonate derivatives useful as magnetic resonance imaging agents
US5958523A (en) * 1995-05-19 1999-09-28 Bradic; Marijan Coating and lubricant compositions containing polyfluorfullerenes and methods of use
DE19549656B4 (de) * 1995-05-19 2005-08-25 Marijan Bradic Oberflächenbeschichtung für Werkzeuge, Werkstoffe oder Polymere, deren Herstellung und Verwendung
EP0846003A1 (de) * 1995-08-17 1998-06-10 Monsanto Company Verfahren zur diagnostischen bildanalyse unter verwendung von biokonjugaten von metallkomplexen von stickstoffhaltigen makrocyclischen liganden
DE19603033A1 (de) 1996-01-19 1997-07-24 Schering Ag Perfluoralkylhaltige Metallkomplexe, Verfahren zu deren Herstellung und ihre Verwendung in der NMR-Diagnostik
US5834456A (en) * 1996-02-23 1998-11-10 The Dow Chemical Company Polyazamacrocyclofluoromonoalkylphosphonic acids, and their complexes, for use as contrast agents
ES2123449B1 (es) * 1997-03-06 1999-09-16 Univ Madrid Nac Educacion Procedimiento para la obtencion de imagenes y espectros del ph extracelular por resonancia magnetica con indicadores extrinsecos conteniendo 1h o 19f.
WO1999004826A1 (en) * 1997-07-24 1999-02-04 The Australian National University Method for detection of fibrin clots
US6355224B1 (en) * 1998-09-17 2002-03-12 Massachusetts Institute Of Technology Conductive polymer contrast agent compositions and uses therefor
US6355225B1 (en) * 1999-10-05 2002-03-12 Wm. Marsh Rice University Tda Research, Inc. Fullerene contrast agent for magnetic resonance imaging and spectroscopy
WO2002051301A2 (en) * 2000-11-10 2002-07-04 Wm. Marsh Rice University Fullerene (c60)-based x-ray contrast agent for diagnostic imaging
US20040038946A1 (en) * 2001-04-27 2004-02-26 Wilson Lon J. Fullerene-based drugs targeted to bone
WO2003105762A2 (en) * 2002-06-14 2003-12-24 Actinium Pharmaceuticals Ltd. Treating disease using radium-225
WO2004048301A1 (ja) * 2002-11-27 2004-06-10 Mitsubishi Chemical Corporation 耐酸化性水素化フラーレンの製造方法及びその方法により得られる水素化フラーレン
US20060039521A1 (en) * 2004-06-22 2006-02-23 Schaefer Daniel R Direct production of thermal antineutrons and antiprotons
EP1828111A2 (de) * 2004-11-12 2007-09-05 Neurochem (International) Limited Verfahren und fluorierte zusammensetzungen zur behandlung von amyloidbedingten krankheiten
DE102005005704B4 (de) * 2005-02-03 2010-08-12 Leibniz-Institut Für Festkörper- Und Werkstoffforschung Dresden E.V. Verwendung von Partikeln für die Ermittlung der lokalen Temperatur in organischen und nichtorganischen Körpern
DE102005020379A1 (de) * 2005-05-02 2006-11-16 Johannes-Gutenberg-Universität Mainz Verfahren zur Abbildung der Mikrostruktur der Lunge und eine Vorrichtung hierfür
US20070025918A1 (en) * 2005-07-28 2007-02-01 General Electric Company Magnetic resonance imaging (MRI) agents: water soluble carbon-13 enriched fullerene and carbon nanotubes for use with dynamic nuclear polarization

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4647447A (en) * 1981-07-24 1987-03-03 Schering Aktiengesellschaft Diagnostic media
US5132105A (en) * 1990-02-02 1992-07-21 Quantametrics, Inc. Materials with diamond-like properties and method and means for manufacturing them
US5114477A (en) * 1991-09-03 1992-05-19 Xerox Corporation Liquid ink compositions
GB9203037D0 (en) * 1992-02-11 1992-03-25 Salutar Inc Contrast agents

Also Published As

Publication number Publication date
AU2406292A (en) 1993-03-16
DE69229348D1 (de) 1999-07-08
US5248498A (en) 1993-09-28
EP0599946B1 (de) 1999-06-02
EP0599946A1 (de) 1994-06-08
DE69229348T2 (de) 1999-11-11
WO1993003771A1 (en) 1993-03-04
CA2113996A1 (en) 1993-03-04
JPH06509802A (ja) 1994-11-02
AU657789B2 (en) 1995-03-23

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