ATE183203T1 - Endothelin-antagonisten - Google Patents

Endothelin-antagonisten

Info

Publication number
ATE183203T1
ATE183203T1 AT91403118T AT91403118T ATE183203T1 AT E183203 T1 ATE183203 T1 AT E183203T1 AT 91403118 T AT91403118 T AT 91403118T AT 91403118 T AT91403118 T AT 91403118T AT E183203 T1 ATE183203 T1 AT E183203T1
Authority
AT
Austria
Prior art keywords
representing
residue
leucine
valine
image
Prior art date
Application number
AT91403118T
Other languages
English (en)
Inventor
Gilles Hamon
Eve Mahe
Dung Le-Nguyen
Original Assignee
Hoechst Marion Roussel Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Marion Roussel Inc filed Critical Hoechst Marion Roussel Inc
Application granted granted Critical
Publication of ATE183203T1 publication Critical patent/ATE183203T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/57536—Endothelin, vasoactive intestinal contractor [VIC]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Public Health (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biochemistry (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Endocrinology (AREA)
  • Urology & Nephrology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Dental Preparations (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
AT91403118T 1990-11-21 1991-11-20 Endothelin-antagonisten ATE183203T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9014498A FR2669339B1 (fr) 1990-11-21 1990-11-21 Nouveaux derives peptidiques, procede de preparation et application a titre de medicaments de ces nouveaux derives.

Publications (1)

Publication Number Publication Date
ATE183203T1 true ATE183203T1 (de) 1999-08-15

Family

ID=9402414

Family Applications (1)

Application Number Title Priority Date Filing Date
AT91403118T ATE183203T1 (de) 1990-11-21 1991-11-20 Endothelin-antagonisten

Country Status (10)

Country Link
US (1) US5510331A (de)
EP (1) EP0487410B1 (de)
JP (1) JP3373217B2 (de)
AT (1) ATE183203T1 (de)
CA (1) CA2055902A1 (de)
DE (1) DE69131518T2 (de)
DK (1) DK0487410T3 (de)
ES (1) ES2135389T3 (de)
FR (1) FR2669339B1 (de)
GR (1) GR3031331T3 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6087324A (en) * 1993-06-24 2000-07-11 Takeda Chemical Industries, Ltd. Sustained-release preparation
EP0679658A4 (de) * 1993-06-25 1997-06-04 Kyowa Hakko Kogyo Kk Endothelinantagonisierendes peptid.
EP0698613B1 (de) * 1994-07-25 1999-03-24 Kyowa Hakko Kogyo Co., Ltd. Endothelin-antagonisierendes Peptid
JP2002538135A (ja) 1999-03-01 2002-11-12 エラン ファーマシューティカルズ，インコーポレイテッド α４β７レセプターアンタゴニストとして有用なα−アミノ酢酸誘導体

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE90108T1 (de) * 1987-10-09 1993-06-15 Takeda Chemical Industries Ltd Vasokonstriktor-peptid.
GB8913089D0 (en) * 1989-06-07 1989-07-26 Ciba Geigy Japan Ltd Novel endothelin derivative
WO1992002237A1 (en) * 1990-08-08 1992-02-20 The Rockefeller University Analogs of endothelin

Also Published As

Publication number Publication date
DK0487410T3 (da) 2000-03-27
EP0487410B1 (de) 1999-08-11
FR2669339B1 (fr) 1995-03-03
CA2055902A1 (fr) 1992-05-22
FR2669339A1 (fr) 1992-05-22
DE69131518D1 (de) 1999-09-16
ES2135389T3 (es) 1999-11-01
JP3373217B2 (ja) 2003-02-04
US5510331A (en) 1996-04-23
EP0487410A2 (de) 1992-05-27
EP0487410A3 (en) 1992-09-30
GR3031331T3 (en) 1999-12-31
DE69131518T2 (de) 2000-01-13
JPH04283600A (ja) 1992-10-08

Similar Documents

Publication Publication Date Title
WO2000012541A3 (en) Cytotoxic peptides modified by bulky or lipophilic moieties
DK1310558T3 (da) Stabile produkter af det baktericide/permeabilitetsforögende protein og farmaceutiske sammensætninger, der indeholder disse
DE69220861D1 (de) Zyklische Peptide und ihre Verwendung
DK0776209T3 (da) Polynukleinsyrer og proteiner fra et porcin reproduktiv og respiratorisk syndrom-virus og anvendelser deraf
IL109585A0 (en) Peptidic ketones as interleukin-1 beta protease activity inhibitors and pharmaceutical compositions containing them
KR910700062A (ko) 마가이닌 펩타이드의 결실 동족체
HU9201470D0 (en) Process for the production of new polypeptides that show affininty towards lipoposaccharides
DK539483A (da) Fremgangsmaade til fremstilling af peptider
ES2176456T3 (es) Procedimiento de preparacion de un compuesto inhibidor del vih proteasa.
FR2647677B1 (fr) Nouvelles micro-proteines, procede de preparation et application a titre de medicaments de ces nouvelles micro-proteines
ES2081442T3 (es) Proteasa de bacillus licheniformis.
ATE213499T1 (de) Peptidanaloge des menschlichen, basischen myelinproteins mit substitution an position 91 zur behandlung der multiplen sklerose
AU2001284419A1 (en) Novel polypeptides and anti-hiv drugs containing the same
NO971621L (no) Keratinocyttvekstfaktoranaloger
ATE183203T1 (de) Endothelin-antagonisten
DK0783521T3 (da) Polypeptidforbindelser indeholdende D-2-alkyltryptophan, hvilke er i stand til at fremme frigivelsen af væksthormon
DK0556124T3 (da) Hidtil ukendte peptidderivater deres fremstilling og anvendelse som lægemidler
DE69104220D1 (de) Verfahren zur Herstellung von direktkomprimierten, Cephalosporansäure Derivate enthaltendenTabletten.
DE3751398D1 (de) Substrat-Peptide.
ATE30919T1 (de) Magensekretion hemmende peptidderivate, verfahren zu ihrer herstellung und sie enthaltende arzneimittel.
DK0732339T3 (da) Peptider fra HIV-gag-proteinet, fremstilling og anvendelse deraf
NO952748D0 (no) Polypeptid som spesifikt inhiberer Cathepsin L.
ES8401320A1 (es) "un procedimiento para preparar composiciones farmaceuticas a base de sales de teofilina y aminoacidos basicos".
ES2052447A1 (es) Peptidos hemorreguladores.

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee