ATE192158T1 - Ethylenische ungesättigte verbindungen - Google Patents
Ethylenische ungesättigte verbindungenInfo
- Publication number
- ATE192158T1 ATE192158T1 AT95901536T AT95901536T ATE192158T1 AT E192158 T1 ATE192158 T1 AT E192158T1 AT 95901536 T AT95901536 T AT 95901536T AT 95901536 T AT95901536 T AT 95901536T AT E192158 T1 ATE192158 T1 AT E192158T1
- Authority
- AT
- Austria
- Prior art keywords
- pct
- reaction
- date
- solvent
- sec
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title 1
- WEVYAHXRMPXWCK-UHFFFAOYSA-N Acetonitrile Chemical group CC#N WEVYAHXRMPXWCK-UHFFFAOYSA-N 0.000 abstract 3
- 239000002904 solvent Substances 0.000 abstract 3
- 238000006243 chemical reaction Methods 0.000 abstract 2
- 239000003153 chemical reaction reagent Substances 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 239000000047 product Substances 0.000 abstract 2
- GETQZCLCWQTVFV-UHFFFAOYSA-N trimethylamine Chemical compound CN(C)C GETQZCLCWQTVFV-UHFFFAOYSA-N 0.000 abstract 2
- YLPYFBTUGJDBLX-UHFFFAOYSA-N C[N+](C)(C)COP([O-])(O)=O Chemical compound C[N+](C)(C)COP([O-])(O)=O YLPYFBTUGJDBLX-UHFFFAOYSA-N 0.000 abstract 1
- 239000006227 byproduct Substances 0.000 abstract 1
- 229920001577 copolymer Polymers 0.000 abstract 1
- 239000000017 hydrogel Substances 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- GWLJTAJEHRYMCA-UHFFFAOYSA-N phospholane Chemical compound C1CCPC1 GWLJTAJEHRYMCA-UHFFFAOYSA-N 0.000 abstract 1
- 239000007858 starting material Substances 0.000 abstract 1
- 238000007039 two-step reaction Methods 0.000 abstract 1
- -1 unsaturated phosphate ester compounds Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6564—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms
- C07F9/6571—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and oxygen atoms as the only ring hetero atoms
- C07F9/6574—Esters of oxyacids of phosphorus
- C07F9/65742—Esters of oxyacids of phosphorus non-condensed with carbocyclic rings or heterocyclic rings or ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/06—Phosphorus compounds without P—C bonds
- C07F9/08—Esters of oxyacids of phosphorus
- C07F9/09—Esters of phosphoric acids
- C07F9/091—Esters of phosphoric acids with hydroxyalkyl compounds with further substituents on alkyl
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB939324033A GB9324033D0 (en) | 1993-11-23 | 1993-11-23 | Ethylenically unsaturated compounds |
| PCT/GB1994/002571 WO1995014702A1 (en) | 1993-11-23 | 1994-11-23 | Ethylenically unsaturated compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE192158T1 true ATE192158T1 (de) | 2000-05-15 |
Family
ID=10745542
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT95901536T ATE192158T1 (de) | 1993-11-23 | 1994-11-23 | Ethylenische ungesättigte verbindungen |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US5741923A (de) |
| EP (1) | EP0730599B1 (de) |
| JP (1) | JP2877958B2 (de) |
| AT (1) | ATE192158T1 (de) |
| AU (1) | AU683965B2 (de) |
| CA (1) | CA2175801A1 (de) |
| DE (1) | DE69424180T2 (de) |
| GB (1) | GB9324033D0 (de) |
| WO (1) | WO1995014702A1 (de) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9521234D0 (en) * | 1995-10-16 | 1995-12-20 | Biocompatibles Ltd | Synthesis of polymerisable phospho diesters |
| WO1997014702A1 (en) * | 1995-10-16 | 1997-04-24 | Biocompatibles Limited | Oxidation of phosphorus compounds |
| JP3052923B2 (ja) * | 1997-05-30 | 2000-06-19 | 日本油脂株式会社 | （メタ）アクリレート誘導体の製造方法 |
| EP0922709B1 (de) * | 1997-05-30 | 2003-07-09 | Nof Corporation | Verfahren zur herstellung von (meth)acrylatderivaten |
| ES2657628T3 (es) | 2006-02-28 | 2018-03-06 | Kodiak Sciences Inc. | Conjugados poliméricos que contienen acriloiloxietilfosforilcolina y su preparación |
| CN101181647B (zh) * | 2006-07-18 | 2013-05-15 | 上海市肿瘤研究所 | 仿生磷脂聚合物细胞膜及其制备方法和用途 |
| US8765432B2 (en) | 2009-12-18 | 2014-07-01 | Oligasis, Llc | Targeted drug phosphorylcholine polymer conjugates |
| WO2013033553A1 (en) | 2011-09-01 | 2013-03-07 | Vertellus Specialties Inc. | Methods for producing biocompatible materials |
| EP2751123B1 (de) | 2011-09-01 | 2017-08-02 | Vertellus Holdings LLC | Biokompatibles material |
| GB201119363D0 (en) | 2011-11-10 | 2011-12-21 | Vertellus Specialities Inc | Polymerisable material |
| EP3760639B1 (de) | 2013-09-08 | 2025-10-22 | Kodiak Sciences Inc. | Zwitterionische polymere zur verwendung als konjugate mit faktor-viii |
| US9840553B2 (en) | 2014-06-28 | 2017-12-12 | Kodiak Sciences Inc. | Dual PDGF/VEGF antagonists |
| KR102210104B1 (ko) | 2014-10-17 | 2021-02-01 | 코디악 사이언시스 인코포레이티드 | 부티릴콜린에스테라제 양성이온성 중합체 컨쥬게이트 |
| SG11201805420SA (en) | 2015-12-30 | 2018-07-30 | Kodiak Sciences Inc | Antibodies and conjugates thereof |
| JP6777812B2 (ja) | 2016-10-19 | 2020-10-28 | アルコン インク． | ペンダントチオール基を有する親水性コポリマー |
| JP6777814B2 (ja) | 2016-10-19 | 2020-10-28 | アルコン インク． | １個のチオール含有末端基を有する親水性コポリマー |
| CN109844570A (zh) | 2016-10-26 | 2019-06-04 | 诺华股份有限公司 | 在其上具有共价附接的润滑涂层的软性接触镜片 |
| CA3092588A1 (en) | 2018-03-02 | 2019-09-06 | Kodiak Sciences Inc. | Il-6 antibodies and fusion constructs and conjugates thereof |
| AU2020364071A1 (en) | 2019-10-10 | 2022-05-26 | Kodiak Sciences Inc. | Methods of treating an eye disorder |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2270887A1 (en) * | 1974-05-16 | 1975-12-12 | Chabrier De Lassauniere Pierre | Prepn of lecithins and glycol-lecithins - by reaction of trimethylamine with 2-substd-2-oxo-1,3,2-dioxaphospholans |
| JPS58154591A (ja) * | 1982-03-09 | 1983-09-14 | Tadao Nakaya | リン脂質類似モノマ−の製造法 |
| JPS60184093A (ja) * | 1984-03-01 | 1985-09-19 | Mitsubishi Chem Ind Ltd | リン脂質類似モノマ−の製造法 |
| GB9023498D0 (en) * | 1990-10-29 | 1990-12-12 | Biocompatibles Ltd | Soft contact lens material |
| RU2167886C2 (ru) * | 1991-07-05 | 2001-05-27 | Биокомпэтиблз Лимитед. | Полимер, способ получения полимера, поверхность с покрытием, способ покрытия поверхности |
| GB9118597D0 (en) * | 1991-08-30 | 1991-10-16 | Biocompatibles Ltd | Polymer treatments |
| JPH0621599A (ja) * | 1992-07-02 | 1994-01-28 | Matsushita Electric Works Ltd | 金属ベース配線基板 |
| US5466853A (en) * | 1992-07-23 | 1995-11-14 | Nof Corporation | Diester monomer, its polymer, water-containing soft contact lens, and processing solution for contact lens |
-
1993
- 1993-11-23 GB GB939324033A patent/GB9324033D0/en active Pending
-
1994
- 1994-11-23 DE DE69424180T patent/DE69424180T2/de not_active Expired - Lifetime
- 1994-11-23 EP EP95901536A patent/EP0730599B1/de not_active Expired - Lifetime
- 1994-11-23 AT AT95901536T patent/ATE192158T1/de not_active IP Right Cessation
- 1994-11-23 US US08/704,519 patent/US5741923A/en not_active Expired - Lifetime
- 1994-11-23 WO PCT/GB1994/002571 patent/WO1995014702A1/en not_active Ceased
- 1994-11-23 CA CA002175801A patent/CA2175801A1/en not_active Abandoned
- 1994-11-23 JP JP7514911A patent/JP2877958B2/ja not_active Expired - Lifetime
- 1994-11-23 AU AU10733/95A patent/AU683965B2/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| JP2877958B2 (ja) | 1999-04-05 |
| EP0730599B1 (de) | 2000-04-26 |
| US5741923A (en) | 1998-04-21 |
| CA2175801A1 (en) | 1995-06-01 |
| DE69424180D1 (de) | 2000-05-31 |
| EP0730599A1 (de) | 1996-09-11 |
| GB9324033D0 (en) | 1994-01-12 |
| JPH09505578A (ja) | 1997-06-03 |
| AU683965B2 (en) | 1997-11-27 |
| AU1073395A (en) | 1995-06-13 |
| DE69424180T2 (de) | 2000-09-21 |
| WO1995014702A1 (en) | 1995-06-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |