ATE194839T1 - Pyridinderivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zubereitungen - Google Patents

Pyridinderivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zubereitungen

Info

Publication number
ATE194839T1
ATE194839T1 AT96400778T AT96400778T ATE194839T1 AT E194839 T1 ATE194839 T1 AT E194839T1 AT 96400778 T AT96400778 T AT 96400778T AT 96400778 T AT96400778 T AT 96400778T AT E194839 T1 ATE194839 T1 AT E194839T1
Authority
AT
Austria
Prior art keywords
alkyl
aryl
substd
arylalkyl
cycloalkyl
Prior art date
Application number
AT96400778T
Other languages
English (en)
Inventor
Marie-Claude Viaud
Gerald Guillaumet
Daniel Mazeas
Herve Vandepoel
Pierre Renard
Bruno Pfeiffer
Philippe Delagrange
Original Assignee
Adir
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Adir filed Critical Adir
Application granted granted Critical
Publication of ATE194839T1 publication Critical patent/ATE194839T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pyridine Compounds (AREA)
AT96400778T 1995-04-14 1996-04-11 Pyridinderivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zubereitungen ATE194839T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9504504A FR2732969B1 (fr) 1995-04-14 1995-04-14 Nouveaux composes pyridiniques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent

Publications (1)

Publication Number Publication Date
ATE194839T1 true ATE194839T1 (de) 2000-08-15

Family

ID=9478127

Family Applications (1)

Application Number Title Priority Date Filing Date
AT96400778T ATE194839T1 (de) 1995-04-14 1996-04-11 Pyridinderivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zubereitungen

Country Status (16)

Country Link
US (1) US5714495A (de)
EP (1) EP0737685B1 (de)
JP (1) JP3723274B2 (de)
CN (1) CN1058967C (de)
AT (1) ATE194839T1 (de)
AU (1) AU700071B2 (de)
CA (1) CA2174033C (de)
DE (1) DE69609371T2 (de)
DK (1) DK0737685T5 (de)
ES (1) ES2150642T3 (de)
FR (1) FR2732969B1 (de)
GR (1) GR3034620T3 (de)
NO (1) NO305988B1 (de)
NZ (1) NZ286360A (de)
PT (1) PT737685E (de)
ZA (1) ZA962934B (de)

Families Citing this family (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5977131A (en) * 1997-04-09 1999-11-02 Pfizer Inc. Azaindole-ethylamine derivatives as nicotinic acetylcholine receptor binding agents
EP1178045B1 (de) * 1997-04-09 2003-05-28 Pfizer Inc. Azindolethylaminderivate als Nikotin-acetylcholin-Rezeptor Bindung Verbindungen
FR2763335B1 (fr) * 1997-05-16 2000-11-24 Adir Nouveaux composes heterocycliques substitues, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
BR9812944A (pt) 1997-10-20 2000-08-08 Hoffmann La Roche Inibidores bicìclicos da cinase
WO1999051233A1 (en) * 1998-04-02 1999-10-14 Merck & Co., Inc. Antagonists of gonadotropin releasing hormone
CA2326143A1 (en) * 1998-04-02 1999-10-14 Merck & Co., Inc. Antagonists of gonadotropin releasing hormone
AU3117899A (en) * 1998-04-02 1999-10-25 Merck & Co., Inc. Antagonists of gonadotropin releasing hormone
US6025366A (en) * 1998-04-02 2000-02-15 Merck & Co., Inc. Antagonists of gonadotropin releasing hormone
JP2002510631A (ja) * 1998-04-02 2002-04-09 メルク エンド カムパニー インコーポレーテッド 性腺刺激ホルモン放出ホルモン拮抗薬
US6228867B1 (en) 1998-04-02 2001-05-08 Merck & Co., Inc. Antagonists of gonadotropin releasing hormone
US6110931A (en) * 1998-04-02 2000-08-29 Merck & Co., Inc. Antagonists of gonadotropin releasing hormone
US6232320B1 (en) 1998-06-04 2001-05-15 Abbott Laboratories Cell adhesion-inhibiting antiinflammatory compounds
KR20010102355A (ko) * 1999-02-26 2001-11-15 피터 지. 스트링거 5-ｈｔ1ｆ 효능제
US6696439B1 (en) 1999-02-26 2004-02-24 Eli Lilly And Company 5-HT1F agonists
FR2799757B1 (fr) * 1999-10-15 2001-12-14 Adir Nouveaux derives polycycliques azaindoliques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
WO2001047922A2 (en) * 1999-12-24 2001-07-05 Aventis Pharma Limited Azaindoles
GB0108770D0 (en) 2001-04-06 2001-05-30 Eisai London Res Lab Ltd Inhibitors
GB0115109D0 (en) 2001-06-21 2001-08-15 Aventis Pharma Ltd Chemical compounds
US6921762B2 (en) 2001-11-16 2005-07-26 Amgen Inc. Substituted indolizine-like compounds and methods of use
SI1474420T1 (sl) * 2002-02-01 2012-06-29 Astrazeneca Ab Spojine kinazolina
DE60316542T2 (de) 2002-03-28 2008-07-03 Eisai R&D Management Co., Ltd. 7-azaindole als inhibitoren c-jun n-terminaler kinasen zur behandlung neurodegenerativer störungen
WO2003082869A1 (en) 2002-03-28 2003-10-09 Eisai Co., Ltd. Azaindoles as inhibitors of c-jun n-terminal kinases
EP1558252B1 (de) 2002-08-02 2007-10-10 Merck & Co., Inc. Substituierte furo[2,3-b]pyridin derivate
EP2295433A3 (de) * 2003-03-06 2011-07-06 Eisai R&D Management Co., Ltd. JNK Inhibitoren
GB0305142D0 (en) 2003-03-06 2003-04-09 Eisai London Res Lab Ltd Synthesis
US7612086B2 (en) 2003-05-16 2009-11-03 Eisai R & D Management Co. Ltd. JNK inhibitors
GB0405055D0 (en) * 2004-03-05 2004-04-07 Eisai London Res Lab Ltd JNK inhibitors
KR100958829B1 (ko) 2004-09-03 2010-05-25 주식회사유한양행 피롤로[2,3-ｃ]피리딘 유도체 및 그의 제조방법
CA2579127C (en) * 2004-09-03 2011-08-02 Yuhan Corporation Pyrrolo[3,2-b]pyridine derivatives and processes for the preparation thereof
US20060183758A1 (en) * 2005-02-17 2006-08-17 Cb Research And Development, Inc. Method for synthesis of AZA-annelated pyrroles, thiophenes, and furans
GB0516156D0 (en) 2005-08-05 2005-09-14 Eisai London Res Lab Ltd JNK inhibitors
WO2007027855A2 (en) * 2005-09-01 2007-03-08 Array Biopharma Inc. Raf inhibitor compounds and methods of use thereof
CL2007002617A1 (es) 2006-09-11 2008-05-16 Sanofi Aventis Compuestos derivados de pirrolo[2,3-b]pirazin-6-ilo; composicion farmaceutica que comprende a dichos compuestos; y su uso para tratar inflamacion de las articulaciones, artritis reumatoide, tumores, linfoma de las celulas del manto.
CA2671354A1 (en) * 2006-12-08 2008-06-12 Takeda Pharmaceutical Company Limited Tricyclic compound and medical use thereof
WO2011109932A1 (en) * 2010-03-09 2011-09-15 F.Hoffmann-La Roche Ag Novel process for the manufacture of 5-halogenated-7-azaindoles
EP2940022B1 (de) * 2014-04-30 2020-09-02 Masarykova Univerzita Furopyridinen als Inhibitoren von Proteinkinasen
CN106045995B (zh) * 2016-06-13 2017-07-11 菏泽学院 一种5‑溴‑1H‑吡咯并[2,3‑b]吡啶的合成方法
WO2020132384A1 (en) 2018-12-21 2020-06-25 Celgene Corporation Thienopyridine inhibitors of ripk2
WO2025000051A1 (en) 2023-06-28 2025-01-02 Psylo Pty Ltd Pyrrolopyridine compounds for the treatment of mental illnesses

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2680366B1 (fr) * 1991-08-13 1995-01-20 Adir Nouveaux derives d'arylethylamines, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent.
US5552428A (en) * 1992-06-24 1996-09-03 Instituto Farmacologico Lombardo-Iflo, S.A.S. Compounds effective in the treatment of circadian rhythms and related disorders, the novel pharmaceutical preparations and novel method of application
JPH10510510A (ja) * 1994-06-09 1998-10-13 スミスクライン・ビーチャム・コーポレイション エンドセリン受容体拮抗物質
JPH10503501A (ja) * 1994-08-03 1998-03-31 アスタ メディカ アクチエンゲゼルシャフト 抗喘息、抗アレルギー、抗炎症及び免疫修飾作用を有するインドール、インダゾール、ピリドピロール及びピリドピラゾール誘導体
US5541228A (en) * 1994-10-14 1996-07-30 Bristol-Myers Squibb Co. Melatonergic agents

Also Published As

Publication number Publication date
JPH08291172A (ja) 1996-11-05
CN1139111A (zh) 1997-01-01
NO305988B1 (no) 1999-08-30
AU700071B2 (en) 1998-12-17
JP3723274B2 (ja) 2005-12-07
DK0737685T5 (da) 2001-01-02
FR2732969A1 (fr) 1996-10-18
FR2732969B1 (fr) 1997-05-16
EP0737685A1 (de) 1996-10-16
NO961457L (no) 1996-10-15
AU5062996A (en) 1996-10-24
DE69609371T2 (de) 2001-02-22
NO961457D0 (no) 1996-04-12
ZA962934B (en) 1996-10-17
GR3034620T3 (en) 2001-01-31
ES2150642T3 (es) 2000-12-01
DK0737685T3 (da) 2000-10-09
PT737685E (pt) 2000-10-31
CA2174033A1 (fr) 1996-10-15
CN1058967C (zh) 2000-11-29
CA2174033C (fr) 2001-07-24
EP0737685B1 (de) 2000-07-19
NZ286360A (en) 1997-09-22
DE69609371D1 (de) 2000-08-24
US5714495A (en) 1998-02-03

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee