DK0779929T5 - Ikke-selvinaktiverende, ekspressionsmålrettede retrovirale vektorer - Google Patents

Ikke-selvinaktiverende, ekspressionsmålrettede retrovirale vektorer

Info

Publication number
DK0779929T5
DK0779929T5 DK95931969T DK95931969T DK0779929T5 DK 0779929 T5 DK0779929 T5 DK 0779929T5 DK 95931969 T DK95931969 T DK 95931969T DK 95931969 T DK95931969 T DK 95931969T DK 0779929 T5 DK0779929 T5 DK 0779929T5
Authority
DK
Denmark
Prior art keywords
region
self
retroviral vectors
targeted retroviral
inactivating expression
Prior art date
Application number
DK95931969T
Other languages
Danish (da)
English (en)
Other versions
DK0779929T3 (da
Inventor
Walter Henry Guenzburg
Robert Michael Saller
Original Assignee
Gsf Forschungszentrum Umwelt
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gsf Forschungszentrum Umwelt filed Critical Gsf Forschungszentrum Umwelt
Publication of DK0779929T3 publication Critical patent/DK0779929T3/da
Application granted granted Critical
Publication of DK0779929T5 publication Critical patent/DK0779929T5/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86—Viral vectors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/13011—Gammaretrovirus, e.g. murine leukeamia virus
    • C12N2740/13041—Use of virus, viral particle or viral elements as a vector
    • C12N2740/13043—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Virology (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Plant Pathology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Ceramic Products (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Traffic Control Systems (AREA)
  • Navigation (AREA)
  • Molds, Cores, And Manufacturing Methods Thereof (AREA)
  • Road Signs Or Road Markings (AREA)
  • Electrotherapy Devices (AREA)
  • Ultra Sonic Daignosis Equipment (AREA)
DK95931969T 1994-09-02 1995-09-01 Ikke-selvinaktiverende, ekspressionsmålrettede retrovirale vektorer DK0779929T5 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DK101794 1994-09-02
PCT/EP1995/003445 WO1996007748A1 (en) 1994-09-02 1995-09-01 Non self-inactivating, expression targeted retroviral vectors

Publications (2)

Publication Number Publication Date
DK0779929T3 DK0779929T3 (da) 2001-05-07
DK0779929T5 true DK0779929T5 (da) 2001-08-13

Family

ID=8100062

Family Applications (1)

Application Number Title Priority Date Filing Date
DK95931969T DK0779929T5 (da) 1994-09-02 1995-09-01 Ikke-selvinaktiverende, ekspressionsmålrettede retrovirale vektorer

Country Status (20)

Country Link
US (1) US7531353B1 (de)
EP (1) EP0779929B1 (de)
JP (1) JP4037446B2 (de)
CN (1) CN1117156C (de)
AT (1) ATE200517T1 (de)
AU (1) AU688590B2 (de)
BR (1) BR9508664A (de)
CA (1) CA2198210C (de)
DE (1) DE69520681T2 (de)
DK (1) DK0779929T5 (de)
EE (1) EE03492B1 (de)
ES (1) ES2156945T3 (de)
FI (1) FI970892L (de)
HU (1) HU221607B (de)
MX (1) MX9701544A (de)
NO (1) NO317731B1 (de)
NZ (1) NZ292897A (de)
PL (1) PL184375B1 (de)
RU (1) RU2199585C2 (de)
WO (1) WO1996007748A1 (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2198210C (en) 1994-09-02 2006-07-11 Gsf - Forschungszentrum Fur Umwelt Und Gesundheit Gmbh Non self-inactivating, expression targeted retroviral vectors
JP3908274B2 (ja) * 1995-03-09 2007-04-25 ゲーエスエフ−フォルシュンクスツェントラム・フュア・ウムベルト・ウント・ゲズントハイト・ゲーエムベーハー 遺伝子治療用の抗菌ペプチドをコードする治療用遺伝子を有するベクター
ATE309000T1 (de) 1995-06-27 2005-11-15 Bavarian Nordic As Verkapselte zellen die virenpartikeln produzieren
US7074398B1 (en) 1995-10-13 2006-07-11 Gsf-Forschungszentrum Fuer Umwelt Und Gesundheit Gmbh Retroviral vectors carrying senescent cell derived inhibitors 1 (SDI-1)or antisense SDI-1 nucleotide sequences
DE69621035T2 (de) * 1995-10-13 2003-01-02 Austrian Nordic Biotherapeutics Ag, Wien Retrovirale vektoren die inhibitoren der dna synthese (sdi-1) oder antisense sdi-1 nukleotid sequenzen tragen
RU2185821C2 (ru) 1996-03-27 2002-07-27 Бавариан Нордик Рисерч Инститьют А/С Трансдуцирующие цитохром р450 ретровирусные векторы
US6540995B1 (en) 1996-03-27 2003-04-01 Bavarian Nordic Research Institute Gmbh Encapsulated cells producing cytochrome P450
WO1999032646A1 (en) * 1997-12-22 1999-07-01 Oxford Biomedica (Uk) Limited Equine infectious anaemia virus (eiav) based
EP0961830A1 (de) * 1997-01-29 1999-12-08 Neurosearch A/S Expressionvektoren und methoden zur in vivo expression von therapeutischen polypeptiden
EP1045922B1 (de) 1998-01-06 2004-09-29 Institut für Virologie Teilrechtsfähiges Institut an der Veterinärmedizinischen Universität Wien Rekonstituierender retroviraler vektor (recon vektor) für gezielte genexpression
FR2778670B1 (fr) * 1998-05-18 2002-12-13 Rhone Poulenc Rorer Sa Methodes et compositions pour la production de particules virales
DE19910650A1 (de) * 1999-03-10 2000-09-21 Gsf Forschungszentrum Umwelt Auf HERV-LTR-Sequenzen basierende retrovirale Expressionsvektoren
EP1173597A1 (de) * 1999-04-29 2002-01-23 Aarhus University Expression von heterologen genen von einer ires-translationskassette in retroviralen vektoren
WO2002064805A2 (en) * 2001-02-09 2002-08-22 Institut für Virologie Teilrechtsfähiges Institut an der Veterinärmedizinischen Universität Wien Replication competent non-mammalian retroviral vectors
DE102009021592A1 (de) * 2009-05-15 2010-11-18 Medizinische Hochschule Hannover ASLV-Vektorsystem
CN120866241B (zh) * 2025-09-28 2026-01-30 深圳细胞谷生物医药有限公司 通过稳定细胞系生产工程化类病毒颗粒的方法及其工程化类病毒颗粒

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1989011539A1 (en) 1988-05-17 1989-11-30 Sloan-Kettering Institute For Cancer Research Retroviral vector
GB8919607D0 (en) * 1989-08-30 1989-10-11 Wellcome Found Novel entities for cancer therapy
WO1994029437A1 (en) * 1993-06-07 1994-12-22 University Of Medicine & Dentistry Of New Jersey Highly-efficient, self-inactivating, recombination-free, u3-free retroviral vectors
CA2198210C (en) 1994-09-02 2006-07-11 Gsf - Forschungszentrum Fur Umwelt Und Gesundheit Gmbh Non self-inactivating, expression targeted retroviral vectors
JP3908274B2 (ja) * 1995-03-09 2007-04-25 ゲーエスエフ−フォルシュンクスツェントラム・フュア・ウムベルト・ウント・ゲズントハイト・ゲーエムベーハー 遺伝子治療用の抗菌ペプチドをコードする治療用遺伝子を有するベクター
JPH11508441A (ja) * 1995-03-09 1999-07-27 ババリアン・ノルディック・リサーチ・インスティテュート・アクティーゼルスカブ 遺伝子治療用の新規組換えｄｎａベクター
US6117681A (en) * 1995-03-29 2000-09-12 Bavarian Nordic Research Inst. A/S Pseudotyped retroviral particles
GB9510272D0 (en) 1995-05-22 1995-07-19 Isis Innovation Retroviral vectors
US7074398B1 (en) * 1995-10-13 2006-07-11 Gsf-Forschungszentrum Fuer Umwelt Und Gesundheit Gmbh Retroviral vectors carrying senescent cell derived inhibitors 1 (SDI-1)or antisense SDI-1 nucleotide sequences

Also Published As

Publication number Publication date
DK0779929T3 (da) 2001-05-07
DE69520681D1 (de) 2001-05-17
ES2156945T3 (es) 2001-08-01
EE03492B1 (et) 2001-08-15
NO970902L (no) 1997-04-24
EP0779929A1 (de) 1997-06-25
PL184375B1 (pl) 2002-10-31
HU221607B (hu) 2002-11-28
MX9701544A (es) 1998-03-31
EP0779929B1 (de) 2001-04-11
DE69520681T2 (de) 2001-11-29
CN1117156C (zh) 2003-08-06
FI970892A0 (fi) 1997-02-28
CA2198210A1 (en) 1996-03-14
RU2199585C2 (ru) 2003-02-27
NZ292897A (en) 1998-08-26
NO317731B1 (no) 2004-12-13
EE9700040A (et) 1997-08-15
CA2198210C (en) 2006-07-11
JP4037446B2 (ja) 2008-01-23
US7531353B1 (en) 2009-05-12
ATE200517T1 (de) 2001-04-15
AU3520195A (en) 1996-03-27
WO1996007748A1 (en) 1996-03-14
CN1159210A (zh) 1997-09-10
HUT76974A (hu) 1998-01-28
FI970892A7 (fi) 1997-02-28
BR9508664A (pt) 1998-01-06
HK1001527A1 (en) 1998-06-26
PL319033A1 (en) 1997-07-21
AU688590B2 (en) 1998-03-12
NO970902D0 (no) 1997-02-27
FI970892L (fi) 1997-02-28
JPH10507628A (ja) 1998-07-28

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