ATE202694T1 - Retinoid enthaltende stabile topische zusammensetzungen - Google Patents

Retinoid enthaltende stabile topische zusammensetzungen

Info

Publication number
ATE202694T1
ATE202694T1 AT94923832T AT94923832T ATE202694T1 AT E202694 T1 ATE202694 T1 AT E202694T1 AT 94923832 T AT94923832 T AT 94923832T AT 94923832 T AT94923832 T AT 94923832T AT E202694 T1 ATE202694 T1 AT E202694T1
Authority
AT
Austria
Prior art keywords
pct
retinoid
compositions containing
topical compositions
sec
Prior art date
Application number
AT94923832T
Other languages
English (en)
Inventor
Vringer Tom De
Harrewijn Antoon Van
Aart Muehlenbruch
Original Assignee
Yamanouchi Europ Bv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8213946&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE202694(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Yamanouchi Europ Bv filed Critical Yamanouchi Europ Bv
Application granted granted Critical
Publication of ATE202694T1 publication Critical patent/ATE202694T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/07—Retinol compounds, e.g. vitamin A
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A61K31/203—Retinoic acids ; Salts thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/39—Derivatives containing from 2 to 10 oxyalkylene groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/67—Vitamins
    • A61K8/671—Vitamin A; Derivatives thereof, e.g. ester of vitamin A acid, ester of retinol, retinol, retinal
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/84—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
    • A61K8/86—Polyethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/90—Block copolymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/16—Emollients or protectives, e.g. against radiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/08—Anti-ageing preparations

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Birds (AREA)
  • General Chemical & Material Sciences (AREA)
  • Dermatology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Emergency Medicine (AREA)
  • Toxicology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Cosmetics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT94923832T 1993-07-01 1994-07-01 Retinoid enthaltende stabile topische zusammensetzungen ATE202694T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP93201931 1993-07-01
PCT/NL1994/000151 WO1995001160A1 (en) 1993-07-01 1994-07-01 Stable topical retinoid compositions

Publications (1)

Publication Number Publication Date
ATE202694T1 true ATE202694T1 (de) 2001-07-15

Family

ID=8213946

Family Applications (1)

Application Number Title Priority Date Filing Date
AT94923832T ATE202694T1 (de) 1993-07-01 1994-07-01 Retinoid enthaltende stabile topische zusammensetzungen

Country Status (23)

Country Link
US (1) US5690923A (de)
EP (1) EP0706370B2 (de)
JP (2) JP3947215B2 (de)
AT (1) ATE202694T1 (de)
AU (1) AU678039B2 (de)
BG (1) BG61713B1 (de)
CA (1) CA2166062C (de)
CZ (1) CZ285679B6 (de)
DE (1) DE69427639T3 (de)
DK (1) DK0706370T4 (de)
ES (1) ES2160631T5 (de)
FI (1) FI115607B (de)
GR (1) GR3036761T3 (de)
HU (1) HU217869B (de)
MD (1) MD1587C2 (de)
NO (1) NO311066B1 (de)
PT (1) PT706370E (de)
RO (1) RO115109B1 (de)
RU (1) RU2134101C1 (de)
SI (1) SI0706370T2 (de)
SK (1) SK279919B6 (de)
UA (1) UA41937C2 (de)
WO (1) WO1995001160A1 (de)

Families Citing this family (43)

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RO115109B1 (ro) * 1993-07-01 1999-11-30 Yamanouchi Europ Bv Compozitie stabila cu retinoid
WO1998018492A1 (fr) * 1996-10-25 1998-05-07 Yoshitomi Pharmaceutical Industries Ltd. Procede pour empecher la precipitation de medicaments
DE19903729A1 (de) * 1999-01-30 2000-08-03 Beiersdorf Ag Verwendung von oberflächenaktiven Citronensäureestern zur Stabilisierung von Retinoiden, synergistische Gemische aus Retinoiden und oberflächenaktiven Substanzen sowie kosmetische und dermatologische Zubereitungen mit einem Gehalt an solchen Gemischen
JP2003507404A (ja) * 1999-08-20 2003-02-25 ユニリーバー・ナームローゼ・ベンノートシヤープ 弱カルボン酸による皮膚刺激を緩和するための皮膚化粧品組成物
DE10025756C2 (de) * 2000-05-25 2003-02-20 Cognis Deutschland Gmbh Lösungsvermittler
RU2166309C1 (ru) * 2000-06-26 2001-05-10 Разумова Татьяна Николаевна Лечебно-профилактическая и косметическая композиция
US6387383B1 (en) 2000-08-03 2002-05-14 Dow Pharmaceutical Sciences Topical low-viscosity gel composition
US7060732B2 (en) * 2000-12-12 2006-06-13 Imaginative Research Associates, Inc. Antibiotic/benzoyl peroxide dispenser
US20060189552A1 (en) * 2000-12-12 2006-08-24 Mohan Vishnupad Dispenser for dispensing three or more actives
RU2197235C1 (ru) * 2002-04-05 2003-01-27 Фармацевтическое научно-производственное предприятие "Ретиноиды" (акционерное общество закрытого типа) Раствор для лечения заболеваний кожи, способ его получения и способ лечения заболеваний кожи
US20110142922A1 (en) * 2002-04-30 2011-06-16 Ferndale Ip, Inc. Stabilized composition and method for dermatological treatment
US20030215493A1 (en) * 2002-04-30 2003-11-20 Patel Pravin M. Composition and method for dermatological treatment
US7939489B2 (en) * 2002-12-23 2011-05-10 Avon Products, Inc. Oil absorbent topical compositions and methods for using same
WO2004064833A1 (en) * 2003-01-24 2004-08-05 Connetics Australia Pty Ltd. Clindamycin phosphate foam
US20060014834A1 (en) * 2004-05-11 2006-01-19 Mohan Vishnupad Retinoid solutions and formulations made therefrom
US7662855B2 (en) * 2004-05-11 2010-02-16 Imaginative Research Associates, Inc. Retinoid solutions and formulations made therefrom
DE602005021238D1 (de) 2004-11-09 2010-06-24 Imaginative Res Associates Inc Retinoidlösungen und formulierungen daraus
AU2005306397A1 (en) * 2004-11-19 2006-05-26 Aventis Pharmaceuticals Inc. Antibiotic compounds, compositions and medical uses
US20060222712A1 (en) * 2005-02-17 2006-10-05 Connetics Corporation Acne gel
AR054805A1 (es) * 2005-06-29 2007-07-18 Stiefel Laboratories Composiciones topicas para el tratamiento de la piel
WO2007092312A2 (en) * 2006-02-03 2007-08-16 Stiefel Laboratories, Inc. Topical skin treating compositions
AU2006339841B2 (en) * 2006-03-08 2012-08-30 Nihon Nohyaku Co., Ltd. Pharmaceutical composition for external use
MX2008011435A (es) * 2006-03-08 2009-02-03 Nihon Nohyaku Co Ltd Composicion farmaceutica para uso externo.
BRPI0709674A2 (pt) 2006-03-31 2011-12-06 Stiefel Research Australia Pty Ltd. gel de suspensão espumante
US20080287373A1 (en) * 2007-05-17 2008-11-20 Popp Karl F Topical skin treating kits
EP2170254A2 (de) * 2007-06-21 2010-04-07 Dow Global Technologies Inc. Stabilisierer für hydrophobe komponenten in körperpflegezusammensetzungen
JP5529539B2 (ja) 2007-09-05 2014-06-25 株式会社ポーラファルマ 医薬組成物
JP5453093B2 (ja) * 2007-09-05 2014-03-26 株式会社ポーラファルマ 抗真菌医薬組成物
JP5345937B2 (ja) 2007-09-05 2013-11-20 株式会社ポーラファルマ 抗真菌組成物
CN101903022A (zh) * 2007-10-18 2010-12-01 梅迪奇斯医药公司 类维生素a和过氧化苯甲酰水凝胶
FR2939683B1 (fr) * 2008-12-17 2012-04-20 Oreal Composition cosmetique comprenant un polyester sulfonique ramifie et un tensioactif particulier et utilisations en coiffage
EP2416758B8 (de) 2009-04-09 2017-10-18 Pola Pharma Inc. Antimykotische pharmazeutische zusammensetzung
US10130610B2 (en) 2009-04-09 2018-11-20 Pola Pharma Inc. Antimycotic pharmaceutical composition
WO2011024620A1 (en) 2009-08-25 2011-03-03 Pola Pharma Inc. Antimycotic pharmaceutical composition
US11071878B2 (en) * 2009-12-31 2021-07-27 Sol-Gel Technologies Ltd. Core stabilized microcapsules, method of their preparation and uses thereof
ES2786103T3 (es) 2011-06-29 2020-10-08 Sol Gel Tech Ltd Formulaciones tópicas estabilizadas que contienen microcápsulas de núcleo-cubierta
JP5865624B2 (ja) * 2011-08-01 2016-02-17 昭和電工株式会社 皮膚外用剤およびその製造方法
JP5865623B2 (ja) * 2011-08-01 2016-02-17 昭和電工株式会社 皮膚外用剤およびその製造方法
FR2991175B1 (fr) * 2012-06-01 2014-12-19 Galderma Res & Dev Compositions pharmaceutiques topiques de type emulsion h/e contenant un retinoide
MD4479C1 (ro) * 2015-02-12 2017-12-31 Валериу НИКУШОР Compoziţie de erbicide şi procedeu de combatere a buruienilor şi ierburilor în culturile de sfeclă de zahăr cu utilizarea acesteia
HUE073201T2 (hu) 2017-07-12 2026-01-28 Sol Gel Tech Ltd Kapszulázott tretinoint tartalmazó készítmények
BR112022023798A2 (pt) 2020-05-22 2023-01-03 Sol Gel Tech Ltd Microcápsulas estabilizadas, método de sua preparação e usos das mesmas
US20260047995A1 (en) * 2024-08-14 2026-02-19 Mary Kay Inc. Cosmetic composition of stabilized retinoid by ph buffer

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US4532133A (en) * 1983-05-24 1985-07-30 Basf Wyandotte Corporation Low temperature stable, emulsifiable vitamin A concentrates
FR2591105B1 (fr) * 1985-12-11 1989-03-24 Moet Hennessy Rech Composition pharmaceutique, notamment dermatologique, ou cosmetique, a base de phases lamellaires lipidiques hydratees ou de liposomes contenant un retinoide ou un analogue structural dudit retinoide tel qu'un carotenoide.
GB8821129D0 (en) * 1988-09-09 1988-10-12 Unilever Plc Cosmetic composition
MY105521A (en) * 1989-04-17 1994-10-31 Healthpoint Ltd Moisturizing vehicle for topical application of vitamin a acid.
DE69029804T2 (de) * 1989-06-07 1997-09-04 Gail S Bazzano VEHIKEL MIT LANGSAMER FREISETZUNG ZUR VERMINDERUNG DER HAUTREIZUNG TOPISCHER retinoidhaltiger MITTEL
JP2827295B2 (ja) * 1989-07-04 1998-11-25 大正製薬株式会社 ビタミンａ類含有点眼剤
FI903483A7 (fi) † 1989-07-13 1991-01-14 Bristol Myers Squibb Co Tretinoiinia sisältäviä stabiileja emulsiovoideformuloita
SU1713555A1 (ru) * 1989-10-04 1992-02-23 Научно-производственное объединение "Аэрозоль" Лосьон дл ухода за жирной кожей лица
US5043356A (en) * 1990-01-19 1991-08-27 Fulton Jr James E Composition and method for rejuvenating skin using vitamin A propionate
JP3031990B2 (ja) * 1990-10-19 2000-04-10 同仁医薬化工株式会社 消炎鎮痛クリーム剤組成物
RO115109B1 (ro) * 1993-07-01 1999-11-30 Yamanouchi Europ Bv Compozitie stabila cu retinoid

Also Published As

Publication number Publication date
EP0706370B1 (de) 2001-07-04
SK159795A3 (en) 1997-03-05
ES2160631T5 (es) 2005-07-16
ES2160631T3 (es) 2001-11-16
MD1587B2 (en) 2001-01-31
HUT74072A (en) 1996-10-28
AU678039B2 (en) 1997-05-15
SI0706370T2 (en) 2005-06-30
AU7391394A (en) 1995-01-24
DK0706370T3 (da) 2001-09-17
EP0706370A1 (de) 1996-04-17
NO955193D0 (no) 1995-12-20
CZ285679B6 (cs) 1999-10-13
MD1587C2 (ro) 2001-06-30
SI0706370T1 (en) 2001-12-31
JP2006328089A (ja) 2006-12-07
US5690923A (en) 1997-11-25
WO1995001160A1 (en) 1995-01-12
FI956204A0 (fi) 1995-12-22
NO955193L (no) 1996-02-08
BG61713B1 (bg) 1998-04-30
EP0706370B2 (de) 2005-01-26
JPH08512049A (ja) 1996-12-17
SK279919B6 (sk) 1999-05-07
CZ348395A3 (en) 1996-04-17
GR3036761T3 (en) 2001-12-31
MD950443A (en) 1997-09-30
UA41937C2 (uk) 2001-10-15
RU2134101C1 (ru) 1999-08-10
RO115109B1 (ro) 1999-11-30
PT706370E (pt) 2001-11-30
DE69427639T2 (de) 2001-10-18
HU217869B (hu) 2000-04-28
CA2166062C (en) 2008-09-16
FI115607B (fi) 2005-06-15
HU9503721D0 (en) 1996-02-28
DE69427639D1 (de) 2001-08-09
NO311066B1 (no) 2001-10-08
CA2166062A1 (en) 1995-01-12
FI956204L (fi) 1995-12-22
DE69427639T3 (de) 2005-08-04
BG100267A (bg) 1996-07-31
DK0706370T4 (da) 2005-04-18
JP3947215B2 (ja) 2007-07-18

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