MD1587C2 - Eteri de 2,6-dihidroxipiridină, procedeu de preparare a lor, compoziţie erbicidă şi metodă de combatere a creşterii plantelor indezirabile - Google Patents

Eteri de 2,6-dihidroxipiridină, procedeu de preparare a lor, compoziţie erbicidă şi metodă de combatere a creşterii plantelor indezirabile Download PDF

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Publication number
MD1587C2
MD1587C2 MD95-0443A MD950443A MD1587C2 MD 1587 C2 MD1587 C2 MD 1587C2 MD 950443 A MD950443 A MD 950443A MD 1587 C2 MD1587 C2 MD 1587C2
Authority
MD
Moldova
Prior art keywords
utilization
composition
retinoid
cutaneous application
topical
Prior art date
Application number
MD95-0443A
Other languages
English (en)
Russian (ru)
Other versions
MD950443A (ro
MD1587B2 (ro
Inventor
Tom De Vringer
Antoon VAN HARREWIIN
Aart Muehlenbruch
Original Assignee
Yamanouchi Europe B.V.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8213946&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MD1587(C2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Yamanouchi Europe B.V. filed Critical Yamanouchi Europe B.V.
Publication of MD950443A publication Critical patent/MD950443A/ro
Publication of MD1587B2 publication Critical patent/MD1587B2/ro
Publication of MD1587C2 publication Critical patent/MD1587C2/ro

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/07—Retinol compounds, e.g. vitamin A
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A61K31/203—Retinoic acids ; Salts thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/39—Derivatives containing from 2 to 10 oxyalkylene groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/67—Vitamins
    • A61K8/671—Vitamin A; Derivatives thereof, e.g. ester of vitamin A acid, ester of retinol, retinol, retinal
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/84—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
    • A61K8/86—Polyethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/90—Block copolymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/16—Emollients or protectives, e.g. against radiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/08—Anti-ageing preparations

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Birds (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Dermatology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Emergency Medicine (AREA)
  • Toxicology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Cosmetics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Invenţia se referă la compoziţii farmaceutice şi cosmetice apoase cu conţinut deretinoid pentru aplicare topică pe piele.Se revendică compoziţia retinoidă care conţine un vehicul apos, gelifiant, antioxidant, opţional un solvent organic şi o substanţă tensioactivă neionogenă adiţională, selectată din monoesterii polioxietilenici ai unui alcool gras, glicerilesterii polioxietilenici ai unui acid gras, bloc-copolimerii oxidului de etilenă cu oxidul de propilenă. Compoziţia conţine opţional un antibiotic.Totodată se revendică utilizarea compoziţiei în calitate de remediu terapeutic pentru aplicare topică.
MD95-0443A 1993-07-01 1994-07-01 Eteri de 2,6-dihidroxipiridină, procedeu de preparare a lor, compoziţie erbicidă şi metodă de combatere a creşterii plantelor indezirabile MD1587C2 (ro)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP93201931 1993-07-01
PCT/NL1994/000151 WO1995001160A1 (en) 1993-07-01 1994-07-01 Stable topical retinoid compositions

Publications (3)

Publication Number Publication Date
MD950443A MD950443A (ro) 1997-09-30
MD1587B2 MD1587B2 (ro) 2001-01-31
MD1587C2 true MD1587C2 (ro) 2001-06-30

Family

ID=8213946

Family Applications (1)

Application Number Title Priority Date Filing Date
MD95-0443A MD1587C2 (ro) 1993-07-01 1994-07-01 Eteri de 2,6-dihidroxipiridină, procedeu de preparare a lor, compoziţie erbicidă şi metodă de combatere a creşterii plantelor indezirabile

Country Status (23)

Country Link
US (1) US5690923A (ro)
EP (1) EP0706370B2 (ro)
JP (2) JP3947215B2 (ro)
AT (1) ATE202694T1 (ro)
AU (1) AU678039B2 (ro)
BG (1) BG61713B1 (ro)
CA (1) CA2166062C (ro)
CZ (1) CZ285679B6 (ro)
DE (1) DE69427639T3 (ro)
DK (1) DK0706370T4 (ro)
ES (1) ES2160631T5 (ro)
FI (1) FI115607B (ro)
GR (1) GR3036761T3 (ro)
HU (1) HU217869B (ro)
MD (1) MD1587C2 (ro)
NO (1) NO311066B1 (ro)
PT (1) PT706370E (ro)
RO (1) RO115109B1 (ro)
RU (1) RU2134101C1 (ro)
SI (1) SI0706370T2 (ro)
SK (1) SK279919B6 (ro)
UA (1) UA41937C2 (ro)
WO (1) WO1995001160A1 (ro)

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HU217869B (hu) * 1993-07-01 2000-04-28 Yamanouchi Europe B.V. Helyileg alkalmazható stabil vizes retinoid készítmények
EP0974364A4 (en) * 1996-10-25 2000-12-20 Yoshitomi Pharmaceutical METHOD FOR PREVENTING THE PREPARATION OF MEDICINAL PRODUCTS
DE19903729A1 (de) * 1999-01-30 2000-08-03 Beiersdorf Ag Verwendung von oberflächenaktiven Citronensäureestern zur Stabilisierung von Retinoiden, synergistische Gemische aus Retinoiden und oberflächenaktiven Substanzen sowie kosmetische und dermatologische Zubereitungen mit einem Gehalt an solchen Gemischen
MXPA02001778A (es) * 1999-08-20 2002-08-12 Unilever Nv Composiciones cosmeticas para la piel para reducir irritacion de la piel a partir de acidos carboxilicos debiles.
DE10025756C2 (de) * 2000-05-25 2003-02-20 Cognis Deutschland Gmbh Lösungsvermittler
RU2166309C1 (ru) * 2000-06-26 2001-05-10 Разумова Татьяна Николаевна Лечебно-профилактическая и косметическая композиция
US6387383B1 (en) 2000-08-03 2002-05-14 Dow Pharmaceutical Sciences Topical low-viscosity gel composition
US7060732B2 (en) * 2000-12-12 2006-06-13 Imaginative Research Associates, Inc. Antibiotic/benzoyl peroxide dispenser
US20060189552A1 (en) * 2000-12-12 2006-08-24 Mohan Vishnupad Dispenser for dispensing three or more actives
RU2197235C1 (ru) * 2002-04-05 2003-01-27 Фармацевтическое научно-производственное предприятие "Ретиноиды" (акционерное общество закрытого типа) Раствор для лечения заболеваний кожи, способ его получения и способ лечения заболеваний кожи
US20110142922A1 (en) * 2002-04-30 2011-06-16 Ferndale Ip, Inc. Stabilized composition and method for dermatological treatment
US20030215493A1 (en) * 2002-04-30 2003-11-20 Patel Pravin M. Composition and method for dermatological treatment
US7939489B2 (en) * 2002-12-23 2011-05-10 Avon Products, Inc. Oil absorbent topical compositions and methods for using same
ES2637956T3 (es) 2003-01-24 2017-10-18 Stiefel Research Australia Pty Ltd Espuma farmacéutica
US20060014834A1 (en) * 2004-05-11 2006-01-19 Mohan Vishnupad Retinoid solutions and formulations made therefrom
US7662855B2 (en) * 2004-05-11 2010-02-16 Imaginative Research Associates, Inc. Retinoid solutions and formulations made therefrom
ATE467411T1 (de) * 2004-11-09 2010-05-15 Imaginative Res Associates Inc Retinoidlösungen und formulierungen daraus
AU2005306397A1 (en) * 2004-11-19 2006-05-26 Aventis Pharmaceuticals Inc. Antibiotic compounds, compositions and medical uses
WO2006089070A2 (en) * 2005-02-17 2006-08-24 Connetics Corporation Acne gel
AR054805A1 (es) * 2005-06-29 2007-07-18 Stiefel Laboratories Composiciones topicas para el tratamiento de la piel
WO2007092312A2 (en) * 2006-02-03 2007-08-16 Stiefel Laboratories, Inc. Topical skin treating compositions
CA2645070C (en) * 2006-03-08 2014-02-04 Nihon Nohyaku Co., Ltd. Pharmaceutical composition for external use
RU2419429C2 (ru) * 2006-03-08 2011-05-27 Нихон Нохияку Ко.,Лтд. Фармацевтическая композиция для наружного применения
EP2010133B1 (en) 2006-03-31 2016-05-04 Stiefel Research Australia Pty Ltd Foamable suspension gel
US20080287373A1 (en) * 2007-05-17 2008-11-20 Popp Karl F Topical skin treating kits
US20100267840A1 (en) * 2007-06-21 2010-10-21 Jordan Susan L Stabilizers for hydrophobic components in personal care compositions
JP5529539B2 (ja) * 2007-09-05 2014-06-25 株式会社ポーラファルマ 医薬組成物
EP2191827B1 (en) 2007-09-05 2013-10-30 Pola Pharma Inc. Antifungal composition
CN101808639B (zh) * 2007-09-05 2012-12-05 宝丽制药股份有限公司 抗真菌医药组合物
CN101903022A (zh) * 2007-10-18 2010-12-01 梅迪奇斯医药公司 类维生素a和过氧化苯甲酰水凝胶
FR2939683B1 (fr) * 2008-12-17 2012-04-20 Oreal Composition cosmetique comprenant un polyester sulfonique ramifie et un tensioactif particulier et utilisations en coiffage
KR101409792B1 (ko) * 2009-04-09 2014-06-19 니혼노야쿠가부시키가이샤 항진균성 약제학적 조성물
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US11071878B2 (en) * 2009-12-31 2021-07-27 Sol-Gel Technologies Ltd. Core stabilized microcapsules, method of their preparation and uses thereof
EP2726067B1 (en) 2011-06-29 2020-02-19 Sol-Gel Technologies Ltd. Stabilized topical formulations containing core-shell microcapsules
JP5865624B2 (ja) * 2011-08-01 2016-02-17 昭和電工株式会社 皮膚外用剤およびその製造方法
JP5865623B2 (ja) * 2011-08-01 2016-02-17 昭和電工株式会社 皮膚外用剤およびその製造方法
FR2991175B1 (fr) * 2012-06-01 2014-12-19 Galderma Res & Dev Compositions pharmaceutiques topiques de type emulsion h/e contenant un retinoide
MD4479C1 (ro) * 2015-02-12 2017-12-31 Валериу НИКУШОР Compoziţie de erbicide şi procedeu de combatere a buruienilor şi ierburilor în culturile de sfeclă de zahăr cu utilizarea acesteia
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WO1990014833A1 (en) * 1989-06-07 1990-12-13 Bazzano Gail S Slow release vehicles for minimizing skin irritancy of topical compositions

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WO1990014833A1 (en) * 1989-06-07 1990-12-13 Bazzano Gail S Slow release vehicles for minimizing skin irritancy of topical compositions

Also Published As

Publication number Publication date
ES2160631T5 (es) 2005-07-16
AU7391394A (en) 1995-01-24
NO311066B1 (no) 2001-10-08
CZ285679B6 (cs) 1999-10-13
UA41937C2 (uk) 2001-10-15
DK0706370T4 (da) 2005-04-18
SK159795A3 (en) 1997-03-05
ATE202694T1 (de) 2001-07-15
BG100267A (bg) 1996-07-31
EP0706370A1 (en) 1996-04-17
BG61713B1 (bg) 1998-04-30
RO115109B1 (ro) 1999-11-30
SK279919B6 (sk) 1999-05-07
FI115607B (fi) 2005-06-15
GR3036761T3 (en) 2001-12-31
SI0706370T2 (en) 2005-06-30
EP0706370B2 (en) 2005-01-26
PT706370E (pt) 2001-11-30
CZ348395A3 (en) 1996-04-17
JPH08512049A (ja) 1996-12-17
HUT74072A (en) 1996-10-28
SI0706370T1 (en) 2001-12-31
JP2006328089A (ja) 2006-12-07
CA2166062A1 (en) 1995-01-12
FI956204L (fi) 1995-12-22
DE69427639T2 (de) 2001-10-18
NO955193L (no) 1996-02-08
JP3947215B2 (ja) 2007-07-18
HU217869B (hu) 2000-04-28
DE69427639D1 (de) 2001-08-09
AU678039B2 (en) 1997-05-15
DE69427639T3 (de) 2005-08-04
ES2160631T3 (es) 2001-11-16
HU9503721D0 (en) 1996-02-28
MD950443A (ro) 1997-09-30
MD1587B2 (ro) 2001-01-31
NO955193D0 (no) 1995-12-20
RU2134101C1 (ru) 1999-08-10
CA2166062C (en) 2008-09-16
WO1995001160A1 (en) 1995-01-12
US5690923A (en) 1997-11-25
FI956204A0 (fi) 1995-12-22
DK0706370T3 (da) 2001-09-17
EP0706370B1 (en) 2001-07-04

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