ATE207117T1 - Methode zur isolation von glykosyltransferasen - Google Patents
Methode zur isolation von glykosyltransferasenInfo
- Publication number
- ATE207117T1 ATE207117T1 AT93901223T AT93901223T ATE207117T1 AT E207117 T1 ATE207117 T1 AT E207117T1 AT 93901223 T AT93901223 T AT 93901223T AT 93901223 T AT93901223 T AT 93901223T AT E207117 T1 ATE207117 T1 AT E207117T1
- Authority
- AT
- Austria
- Prior art keywords
- immobilized
- glycosyltransferase
- acceptor moiety
- complex
- iteration
- Prior art date
Links
- 108700023372 Glycosyltransferases Proteins 0.000 title abstract 6
- 102000051366 Glycosyltransferases Human genes 0.000 title abstract 5
- 238000000034 method Methods 0.000 title abstract 3
- 108700014210 glycosyltransferase activity proteins Proteins 0.000 title abstract 2
- 238000002955 isolation Methods 0.000 title 1
- 150000001720 carbohydrates Chemical class 0.000 abstract 5
- 239000000203 mixture Substances 0.000 abstract 2
- 239000007787 solid Substances 0.000 abstract 2
- 229930186217 Glycolipid Natural products 0.000 abstract 1
- 102000003886 Glycoproteins Human genes 0.000 abstract 1
- 108090000288 Glycoproteins Proteins 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 235000014633 carbohydrates Nutrition 0.000 abstract 1
- 239000003153 chemical reaction reagent Substances 0.000 abstract 1
- 102000045442 glycosyltransferase activity proteins Human genes 0.000 abstract 1
- 150000002632 lipids Chemical class 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 238000003786 synthesis reaction Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/1048—Glycosyltransferases (2.4)
- C12N9/1051—Hexosyltransferases (2.4.1)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/18—Preparation of compounds containing saccharide radicals produced by the action of a glycosyl transferase, e.g. alpha-, beta- or gamma-cyclodextrins
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/26—Preparation of nitrogen-containing carbohydrates
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/814—Enzyme separation or purification
- Y10S435/815—Enzyme separation or purification by sorption
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
- Saccharide Compounds (AREA)
- Enzymes And Modification Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US07/810,858 US5874261A (en) | 1988-09-02 | 1991-12-20 | Method for the purification of glycosyltransferases |
| PCT/US1992/010891 WO1993013198A1 (en) | 1991-12-20 | 1992-12-21 | A method for obtaining glycosyltransferases |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE207117T1 true ATE207117T1 (de) | 2001-11-15 |
Family
ID=25204895
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT93901223T ATE207117T1 (de) | 1991-12-20 | 1992-12-21 | Methode zur isolation von glykosyltransferasen |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US5874261A (de) |
| EP (1) | EP0619837B1 (de) |
| JP (1) | JPH07502412A (de) |
| AT (1) | ATE207117T1 (de) |
| AU (1) | AU685387B2 (de) |
| CA (1) | CA2126213A1 (de) |
| DE (1) | DE69232138T2 (de) |
| DK (1) | DK0619837T3 (de) |
| ES (1) | ES2162619T3 (de) |
| FI (1) | FI942916A0 (de) |
| NO (1) | NO942317D0 (de) |
| PT (1) | PT619837E (de) |
| RU (1) | RU94034735A (de) |
| WO (1) | WO1993013198A1 (de) |
Families Citing this family (40)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU642253B2 (en) * | 1990-04-16 | 1993-10-14 | Trustees Of The University Of Pennsylvania, The | Saccharide compositions, methods and apparatus for their synthesis |
| EP0481038B1 (de) | 1990-04-16 | 2002-10-02 | The Trustees Of The University Of Pennsylvania | Saccharidzusammensetzungen, Verfahren und Apparate zu deren Synthese |
| US6518051B1 (en) | 1991-04-11 | 2003-02-11 | The Trustees Of The University Of Pennsylvania | Saccharide compositions, methods and apparatus for their synthesis |
| US5665561A (en) * | 1994-06-06 | 1997-09-09 | The Rockefeller University | Modulators of pneumococcal adherence to pulmonary and vascular cells and diagnostic and therapeutic applications |
| US5545553A (en) | 1994-09-26 | 1996-08-13 | The Rockefeller University | Glycosyltransferases for biosynthesis of oligosaccharides, and genes encoding them |
| US6096725A (en) * | 1997-07-02 | 2000-08-01 | Neose Technologies, Inc. | Methods of using αGal oligosaccharides as immune system targeting agents |
| AU1585999A (en) | 1997-11-12 | 1999-05-31 | Neurotherapeutics | Methods for the detection and treatment of disease using a glycosyltransferase |
| US20040204381A1 (en) * | 1997-11-12 | 2004-10-14 | Moskal Joseph R | Detection and treatment of glyco-enzyme-related disease |
| US7223845B2 (en) | 1998-06-16 | 2007-05-29 | The Board Of Regents Of The University Of Oklahoma | Synthetic glycosulfopeptides and methods of synthesis thereof |
| MXPA00012586A (es) | 1998-06-16 | 2004-05-21 | Univ Oklahoma | Glicosulfopeptidos y metodos de sintesis y uso de los mismos. |
| US20030143662A1 (en) * | 1998-06-16 | 2003-07-31 | Cummings Richard D. | Glycosulfopeptide inhibitors of leukocyte rolling and methods of use thereof |
| US20030059915A1 (en) * | 1999-06-15 | 2003-03-27 | Canfield William M. | Core 1 beta3-galactosyl transferases and methods of use thereof |
| US20030235884A1 (en) * | 1999-06-15 | 2003-12-25 | Cummings Richard D. | Polynucleotides encoding core 1 beta3-galactosyl transferase and methods of use thereof |
| US6492152B1 (en) | 1999-06-15 | 2002-12-10 | The Board Of Regents Of The University Of Oklahoma | Core 1 β3-galactosyl transferases and methods of use thereof |
| US6759241B1 (en) | 1999-10-04 | 2004-07-06 | University Of Maryland Biotechnology Institute | Adjuvant comprising a lipopolysaccharide antagonist |
| US7173003B2 (en) | 2001-10-10 | 2007-02-06 | Neose Technologies, Inc. | Granulocyte colony stimulating factor: remodeling and glycoconjugation of G-CSF |
| US7214660B2 (en) | 2001-10-10 | 2007-05-08 | Neose Technologies, Inc. | Erythropoietin: remodeling and glycoconjugation of erythropoietin |
| WO2003059924A1 (en) * | 2002-01-18 | 2003-07-24 | Biotie Therapies Corporation | Novel binding epitopes for helicobacter pylori and use thereof |
| US7309600B2 (en) | 2003-02-12 | 2007-12-18 | University Of Iowa Research Foundation | Haemophilus influenzae sialyltransferase and methods of use thereof |
| EP1615945B1 (de) | 2003-04-09 | 2011-09-28 | BioGeneriX AG | Glycopegylierungsverfahren und durch die verfahren hergestellte proteine/peptide |
| WO2005012484A2 (en) | 2003-07-25 | 2005-02-10 | Neose Technologies, Inc. | Antibody-toxin conjugates |
| US20080305992A1 (en) | 2003-11-24 | 2008-12-11 | Neose Technologies, Inc. | Glycopegylated erythropoietin |
| EP2497478A3 (de) | 2003-12-05 | 2012-11-07 | Children's Hospital Medical Center | Oligosaccarid-Zusammensetzungen und ihre Verwendung bei der Behandlung von Infektionen |
| EP1814573B1 (de) | 2004-10-29 | 2016-03-09 | ratiopharm GmbH | Remodellierung und glykopegylierung von fibroblasten-wachstumsfaktor (fgf) |
| CA2593682C (en) | 2005-01-10 | 2016-03-22 | Neose Technologies, Inc. | Glycopegylated granulocyte colony stimulating factor |
| EP1871795A4 (de) | 2005-04-08 | 2010-03-31 | Biogenerix Ag | Zusammensetzungen und verfahren zur herstellung von glycosylierungsmutanten eines proteaseresistenten menschlichen wachstumshormons |
| TWI264608B (en) * | 2005-04-08 | 2006-10-21 | Delta Electronics Inc | Light tunnel module |
| US20070105755A1 (en) | 2005-10-26 | 2007-05-10 | Neose Technologies, Inc. | One pot desialylation and glycopegylation of therapeutic peptides |
| WO2007056191A2 (en) | 2005-11-03 | 2007-05-18 | Neose Technologies, Inc. | Nucleotide sugar purification using membranes |
| US9187532B2 (en) | 2006-07-21 | 2015-11-17 | Novo Nordisk A/S | Glycosylation of peptides via O-linked glycosylation sequences |
| US20100075375A1 (en) | 2006-10-03 | 2010-03-25 | Novo Nordisk A/S | Methods for the purification of polypeptide conjugates |
| CN101796063B (zh) | 2007-04-03 | 2017-03-22 | 拉蒂奥法姆有限责任公司 | 使用糖聚乙二醇化g‑csf的治疗方法 |
| WO2008154639A2 (en) | 2007-06-12 | 2008-12-18 | Neose Technologies, Inc. | Improved process for the production of nucleotide sugars |
| CN103497247A (zh) | 2008-02-27 | 2014-01-08 | 诺沃—诺迪斯克有限公司 | 缀合的因子viii分子 |
| CA2757169A1 (en) | 2009-04-13 | 2010-10-21 | Children's Hospital Medical Center | Milk oligosaccharide compositions and use thereof in treating infection in animals |
| UA110325C2 (en) | 2009-07-03 | 2015-12-25 | Australian Biomedical Company Pty Ltd | Medicinal carbohydrates for treating respiratory conditions |
| EP3248605A1 (de) | 2009-07-06 | 2017-11-29 | Children's Hospital Medical Center | Hemmung der entzündung mit milcholigosacchariden |
| CN103764835B (zh) | 2011-06-07 | 2016-08-17 | 海罗公司 | 通过生物技术方法获取低聚糖 |
| US10857167B2 (en) | 2015-04-28 | 2020-12-08 | Children's Hospital Medical Center | Use of oligosaccharide compositions to enhance weight gain |
| RU2624241C1 (ru) * | 2016-03-25 | 2017-07-03 | Акционерное Общество "ГенТерра" | Твердофазный носитель для иммобилизации и/или хранения биологических образцов, содержащих нуклеиновые кислоты |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4184917A (en) * | 1974-04-01 | 1980-01-22 | Sandoz Ltd. | Process for producing a structurally modified interferon |
| US4219571A (en) * | 1978-06-15 | 1980-08-26 | Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo | Process for producing a sweetener |
| US4261976A (en) * | 1978-10-03 | 1981-04-14 | The Massachusetts General Hospital | Method and glycoprotein composition for inhibition of growth of transformed cells and tumors |
| JPS5836959B2 (ja) * | 1980-08-21 | 1983-08-12 | 三井製糖株式会社 | 固定化α−グルコシルトランスフエラ−ゼによるパラチノ−スの製造法 |
| JPS58870A (ja) * | 1981-06-20 | 1983-01-06 | Hayashibara Biochem Lab Inc | 飲食物及びその製造方法 |
| FR2509313A1 (fr) * | 1981-07-08 | 1983-01-14 | Choay Sa | Derives de 3-fucosyl-n-acetyl lactosamine, leur preparation et leurs applications biologiques |
| JPS58149697A (ja) * | 1982-02-27 | 1983-09-06 | Dainippon Ink & Chem Inc | β−１，３グリコシルステビオシドの製造方法 |
| US4569909A (en) * | 1982-06-03 | 1986-02-11 | Seitetsu Kagaku Co., Ltd. | Process for preparing uridine diphosphate-N-acetylgalactosamine |
| US4770994A (en) * | 1982-07-30 | 1988-09-13 | Abbott Laboratories | Determination of carbohydrate acceptors |
| US4557927A (en) * | 1983-03-10 | 1985-12-10 | Kabushiki Kaisha Hoyashibara | Food products and process for producing same |
| GB8316790D0 (en) * | 1983-06-21 | 1983-07-27 | Tate & Lyle Plc | Chemical process |
| DE3446380C1 (de) * | 1984-12-19 | 1986-05-22 | Pfeifer & Langen, 5000 Köln | Suessungsmittel,Verfahren zur Herstellung und Verwendung desselben |
| SE451849B (sv) * | 1985-12-11 | 1987-11-02 | Svenska Sockerfabriks Ab | Sett att syntetisera glykosidiska bindningar samt anvendning av pa detta sett erhallna produkter |
| NL8701616A (nl) * | 1987-07-09 | 1989-02-01 | Stamicarbon | Fructosyltransferase en bereiding van fructose-oligomeren daarmee. |
| SE466403B (sv) * | 1988-03-24 | 1992-02-10 | Kurt G I Nilsson | Saett att syntetisera oligosackarider |
| EP0356048A3 (de) * | 1988-08-05 | 1990-11-14 | Uop | Cyclodextrin-Glycosyl-Transferase |
| DK626488D0 (da) * | 1988-11-10 | 1988-11-10 | Torben Falck Oerntoft | Fremgangsmaade til udtagning af en sekretproeve via en legemsaabning og til praeparation af proeven med henblik paa kvantitativ bestemmelse af molekylaere strukturer og enzymaktivitet i proeven samt proeveudtagningsindretning til brug derved |
| EP0481038B1 (de) * | 1990-04-16 | 2002-10-02 | The Trustees Of The University Of Pennsylvania | Saccharidzusammensetzungen, Verfahren und Apparate zu deren Synthese |
-
1991
- 1991-12-20 US US07/810,858 patent/US5874261A/en not_active Expired - Fee Related
-
1992
- 1992-12-21 ES ES93901223T patent/ES2162619T3/es not_active Expired - Lifetime
- 1992-12-21 CA CA002126213A patent/CA2126213A1/en not_active Abandoned
- 1992-12-21 EP EP93901223A patent/EP0619837B1/de not_active Expired - Lifetime
- 1992-12-21 AU AU33236/93A patent/AU685387B2/en not_active Ceased
- 1992-12-21 DK DK93901223T patent/DK0619837T3/da active
- 1992-12-21 JP JP5511742A patent/JPH07502412A/ja active Pending
- 1992-12-21 WO PCT/US1992/010891 patent/WO1993013198A1/en not_active Ceased
- 1992-12-21 DE DE69232138T patent/DE69232138T2/de not_active Expired - Fee Related
- 1992-12-21 RU RU94034735/13A patent/RU94034735A/ru unknown
- 1992-12-21 PT PT93901223T patent/PT619837E/pt unknown
- 1992-12-21 AT AT93901223T patent/ATE207117T1/de not_active IP Right Cessation
-
1994
- 1994-06-17 NO NO942317A patent/NO942317D0/no unknown
- 1994-06-17 FI FI942916A patent/FI942916A0/fi unknown
Also Published As
| Publication number | Publication date |
|---|---|
| RU94034735A (ru) | 1996-07-20 |
| EP0619837A4 (en) | 1995-11-15 |
| WO1993013198A1 (en) | 1993-07-08 |
| DE69232138D1 (de) | 2001-11-22 |
| NO942317L (de) | 1994-08-09 |
| NO942317D0 (no) | 1994-06-17 |
| ES2162619T3 (es) | 2002-01-01 |
| CA2126213A1 (en) | 1993-06-24 |
| AU685387B2 (en) | 1998-01-22 |
| EP0619837B1 (de) | 2001-10-17 |
| AU3323693A (en) | 1993-07-28 |
| JPH07502412A (ja) | 1995-03-16 |
| PT619837E (pt) | 2002-03-28 |
| DK0619837T3 (da) | 2001-12-03 |
| EP0619837A1 (de) | 1994-10-19 |
| FI942916A7 (fi) | 1994-06-17 |
| FI942916A0 (fi) | 1994-06-17 |
| DE69232138T2 (de) | 2002-06-06 |
| US5874261A (en) | 1999-02-23 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |