ATE214938T1 - Feste, ein cyclosporin und ein anionisches netzmittel enthaltende arzneimittel - Google Patents

Feste, ein cyclosporin und ein anionisches netzmittel enthaltende arzneimittel

Info

Publication number
ATE214938T1
ATE214938T1 AT98943603T AT98943603T ATE214938T1 AT E214938 T1 ATE214938 T1 AT E214938T1 AT 98943603 T AT98943603 T AT 98943603T AT 98943603 T AT98943603 T AT 98943603T AT E214938 T1 ATE214938 T1 AT E214938T1
Authority
AT
Austria
Prior art keywords
suffecting
cyclosporine
anionic
agent
products containing
Prior art date
Application number
AT98943603T
Other languages
English (en)
Inventor
Bernard Charles Sherman
Original Assignee
Bernard Charles Sherman
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bernard Charles Sherman filed Critical Bernard Charles Sherman
Application granted granted Critical
Publication of ATE214938T1 publication Critical patent/ATE214938T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A61K38/13—Cyclosporins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A61K9/1623—Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Transplantation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
AT98943603T 1997-09-16 1998-09-16 Feste, ein cyclosporin und ein anionisches netzmittel enthaltende arzneimittel ATE214938T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
NZ328751A NZ328751A (en) 1997-09-16 1997-09-16 Solid medicament containing an anionic surfactant and cyclosporin
PCT/CA1998/000880 WO1999013900A1 (en) 1997-09-16 1998-09-16 Solid pharmaceutical compositions comprising a cyclosporin and an anionic surfactant

Publications (1)

Publication Number Publication Date
ATE214938T1 true ATE214938T1 (de) 2002-04-15

Family

ID=19926445

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98943603T ATE214938T1 (de) 1997-09-16 1998-09-16 Feste, ein cyclosporin und ein anionisches netzmittel enthaltende arzneimittel

Country Status (23)

Country Link
US (1) US6197335B1 (de)
EP (1) EP0957931B1 (de)
JP (1) JP2001505928A (de)
KR (1) KR20000068991A (de)
CN (1) CN1239432A (de)
AR (1) AR013499A1 (de)
AT (1) ATE214938T1 (de)
AU (1) AU9149198A (de)
BR (1) BR9806212A (de)
CA (1) CA2271447A1 (de)
CZ (1) CZ157099A3 (de)
DE (1) DE69804429D1 (de)
HU (1) HUP0000839A3 (de)
ID (1) ID21683A (de)
IL (1) IL129780A0 (de)
NO (1) NO992340L (de)
NZ (1) NZ328751A (de)
PL (1) PL333353A1 (de)
SI (1) SI9820010A (de)
TR (1) TR199901070T1 (de)
WO (1) WO1999013900A1 (de)
YU (1) YU22399A (de)
ZA (1) ZA988452B (de)

Families Citing this family (54)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5858401A (en) 1996-01-22 1999-01-12 Sidmak Laboratories, Inc. Pharmaceutical composition for cyclosporines
US7732404B2 (en) * 1999-12-30 2010-06-08 Dexcel Ltd Pro-nanodispersion for the delivery of cyclosporin
GB0008785D0 (en) * 2000-04-10 2000-05-31 Novartis Ag Organic compounds
AR033711A1 (es) * 2001-05-09 2004-01-07 Novartis Ag Composiciones farmaceuticas
IL160761A0 (en) * 2001-10-19 2004-08-31 Isotechnika Inc Novel cyclosporin analog microemulsion preconcentrates
GB0307428D0 (en) 2003-03-31 2003-05-07 Medical Res Council Compartmentalised combinatorial chemistry
US20060078893A1 (en) 2004-10-12 2006-04-13 Medical Research Council Compartmentalised combinatorial chemistry by microfluidic control
GB0307403D0 (en) 2003-03-31 2003-05-07 Medical Res Council Selection by compartmentalised screening
US20050059583A1 (en) 2003-09-15 2005-03-17 Allergan, Inc. Methods of providing therapeutic effects using cyclosporin components
US20050221339A1 (en) 2004-03-31 2005-10-06 Medical Research Council Harvard University Compartmentalised screening by microfluidic control
JP4521554B2 (ja) * 2004-03-31 2010-08-11 マイラン製薬株式会社 シクロスポリン製剤
US7968287B2 (en) 2004-10-08 2011-06-28 Medical Research Council Harvard University In vitro evolution in microfluidic systems
US7288520B2 (en) * 2005-07-13 2007-10-30 Allergan, Inc. Cyclosporin compositions
US20070015691A1 (en) 2005-07-13 2007-01-18 Allergan, Inc. Cyclosporin compositions
US7297679B2 (en) 2005-07-13 2007-11-20 Allergan, Inc. Cyclosporin compositions
US7202209B2 (en) 2005-07-13 2007-04-10 Allergan, Inc. Cyclosporin compositions
US7276476B2 (en) * 2005-07-13 2007-10-02 Allergan, Inc. Cyclosporin compositions
US20070015693A1 (en) * 2005-07-13 2007-01-18 Allergan, Inc. Cyclosporin compositions
US7501393B2 (en) 2005-07-27 2009-03-10 Allergan, Inc. Pharmaceutical compositions comprising cyclosporins
US7745400B2 (en) * 2005-10-14 2010-06-29 Gregg Feinerman Prevention and treatment of ocular side effects with a cyclosporin
US9839667B2 (en) 2005-10-14 2017-12-12 Allergan, Inc. Prevention and treatment of ocular side effects with a cyclosporin
WO2007081385A2 (en) 2006-01-11 2007-07-19 Raindance Technologies, Inc. Microfluidic devices and methods of use in the formation and control of nanoreactors
US9562837B2 (en) 2006-05-11 2017-02-07 Raindance Technologies, Inc. Systems for handling microfludic droplets
EP2530167A1 (de) 2006-05-11 2012-12-05 Raindance Technologies, Inc. Mikrofluidische Vorrichtungen
EP2077912B1 (de) 2006-08-07 2019-03-27 The President and Fellows of Harvard College Fluorkohlenstoffemulsionsstabilisierende tenside
WO2008097559A2 (en) 2007-02-06 2008-08-14 Brandeis University Manipulation of fluids and reactions in microfluidic systems
US8592221B2 (en) 2007-04-19 2013-11-26 Brandeis University Manipulation of fluids, fluid components and reactions in microfluidic systems
CA2711984A1 (en) 2008-01-15 2009-07-23 Abbott Gmbh & Co. Kg Powdered protein compositions and methods of making same
EP2262477A1 (de) * 2008-03-04 2010-12-22 F. Hoffmann-La Roche AG Verfahren zur herstellung konzentrierter mizellarer lösungen mit wasseranteil
US12038438B2 (en) 2008-07-18 2024-07-16 Bio-Rad Laboratories, Inc. Enzyme quantification
EP4047367A1 (de) 2008-07-18 2022-08-24 Bio-Rad Laboratories, Inc. Verfahren zum nachweis von zielanalyten unter verwendung von tropfenbibliotheken
WO2010111231A1 (en) 2009-03-23 2010-09-30 Raindance Technologies, Inc. Manipulation of microfluidic droplets
US10520500B2 (en) 2009-10-09 2019-12-31 Abdeslam El Harrak Labelled silica-based nanomaterial with enhanced properties and uses thereof
US10837883B2 (en) 2009-12-23 2020-11-17 Bio-Rad Laboratories, Inc. Microfluidic systems and methods for reducing the exchange of molecules between droplets
US9366632B2 (en) 2010-02-12 2016-06-14 Raindance Technologies, Inc. Digital analyte analysis
US10351905B2 (en) 2010-02-12 2019-07-16 Bio-Rad Laboratories, Inc. Digital analyte analysis
EP4484577A3 (de) 2010-02-12 2025-03-26 Bio-Rad Laboratories, Inc. Digitale analytanalyse
US9399797B2 (en) 2010-02-12 2016-07-26 Raindance Technologies, Inc. Digital analyte analysis
US9562897B2 (en) 2010-09-30 2017-02-07 Raindance Technologies, Inc. Sandwich assays in droplets
EP3412778A1 (de) 2011-02-11 2018-12-12 Raindance Technologies, Inc. Verfahren zur bildung gemischter tröpfchen
WO2012112804A1 (en) 2011-02-18 2012-08-23 Raindance Technoligies, Inc. Compositions and methods for molecular labeling
US8841071B2 (en) 2011-06-02 2014-09-23 Raindance Technologies, Inc. Sample multiplexing
EP3216872B1 (de) 2011-06-02 2020-04-01 Bio-Rad Laboratories, Inc. Enzymquantifizierung
US8658430B2 (en) 2011-07-20 2014-02-25 Raindance Technologies, Inc. Manipulating droplet size
US11901041B2 (en) 2013-10-04 2024-02-13 Bio-Rad Laboratories, Inc. Digital analysis of nucleic acid modification
US9944977B2 (en) 2013-12-12 2018-04-17 Raindance Technologies, Inc. Distinguishing rare variations in a nucleic acid sequence from a sample
WO2015103367A1 (en) 2013-12-31 2015-07-09 Raindance Technologies, Inc. System and method for detection of rna species
US10179120B2 (en) 2014-01-06 2019-01-15 Iron Therapeutics Holdings Ag Dosage regimen of ferric trimaltol
GB201418710D0 (en) 2014-10-21 2014-12-03 Iron Therapeutics Holdings Ag Dosage regimen
US10647981B1 (en) 2015-09-08 2020-05-12 Bio-Rad Laboratories, Inc. Nucleic acid library generation methods and compositions
JP6918204B2 (ja) * 2018-03-19 2021-08-11 大鵬薬品工業株式会社 アルキル硫酸ナトリウムを含む医薬組成物
US20240000705A1 (en) * 2020-09-17 2024-01-04 Catalent U.K. Swindon Zydis Limited Use of surfactant with high molecular weight fish gelatin based dosage formulations to improve flow characteristics
EP4166133B1 (de) * 2021-10-13 2025-07-23 Chugai Seiyaku Kabushiki Kaisha Zusammensetzung mit einer peptidverbindung und einem tensid
TW202406566A (zh) * 2022-05-02 2024-02-16 日商中外製藥股份有限公司 包含用於與界面活性劑結合使用之胜肽化合物的組合物

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL7908722A (nl) 1979-12-03 1981-07-01 Naarden International Nv Werkwijze voor de bereiding van citrussap bevattende dranken met verbeterde troebelingsstabiliteit.
US5639724A (en) * 1984-07-24 1997-06-17 Sandoz Ltd. Cyclosporin galenic forms
JP2577049B2 (ja) 1987-06-04 1997-01-29 三共株式会社 シクロスポリン製剤
US5756450A (en) * 1987-09-15 1998-05-26 Novartis Corporation Water soluble monoesters as solubilisers for pharmacologically active compounds and pharmaceutical excipients and novel cyclosporin galenic forms
US5342625A (en) 1988-09-16 1994-08-30 Sandoz Ltd. Pharmaceutical compositions comprising cyclosporins
CH679277A5 (de) * 1989-02-09 1992-01-31 Sandoz Ag
DD298351A5 (de) * 1989-11-06 1992-02-20 Jenapharm Gmbh,De Verfahren zur herstellung einer carrierabhaengigen arzneiform
JPH0597697A (ja) * 1991-10-02 1993-04-20 Lion Corp 歯槽骨再生剤
US5603955A (en) * 1994-07-18 1997-02-18 University Of Cincinnati Enhanced loading of solutes into polymer gels
IL116674A (en) * 1995-01-09 2003-05-29 Mendell Co Inc Edward Microcrystalline cellulose-based excipient having improved compressibility, pharmaceutical compositions containing the same and methods for the preparation of said excipient and of solid dosage form thereof
US5573783A (en) * 1995-02-13 1996-11-12 Nano Systems L.L.C. Redispersible nanoparticulate film matrices with protective overcoats
IE75744B1 (en) * 1995-04-03 1997-09-24 Elan Corp Plc Controlled release biodegradable micro- and nanospheres containing cyclosporin
IE80467B1 (en) * 1995-07-03 1998-07-29 Elan Corp Plc Controlled release formulations for poorly soluble drugs
JPH1059862A (ja) * 1996-08-16 1998-03-03 Meiji Seika Kaisha Ltd シクロスポリン製剤
US5891845A (en) * 1997-11-21 1999-04-06 Fuisz Technologies Ltd. Drug delivery systems utilizing liquid crystal structures

Also Published As

Publication number Publication date
KR20000068991A (ko) 2000-11-25
TR199901070T1 (xx) 1999-11-22
YU22399A (sh) 2003-01-31
JP2001505928A (ja) 2001-05-08
AU9149198A (en) 1999-04-05
IL129780A0 (en) 2000-02-29
NZ328751A (en) 1999-01-28
DE69804429D1 (de) 2002-05-02
NO992340L (no) 1999-07-06
ID21683A (id) 1999-07-08
CA2271447A1 (en) 1999-03-25
US6197335B1 (en) 2001-03-06
PL333353A1 (en) 1999-12-06
EP0957931A1 (de) 1999-11-24
CZ157099A3 (cs) 1999-09-15
EP0957931B1 (de) 2002-03-27
BR9806212A (pt) 2000-04-18
HUP0000839A2 (hu) 2000-11-28
AR013499A1 (es) 2000-12-27
WO1999013900A1 (en) 1999-03-25
SI9820010A (sl) 1999-08-31
ZA988452B (en) 1999-03-30
HUP0000839A3 (en) 2001-02-28
CN1239432A (zh) 1999-12-22
NO992340D0 (no) 1999-05-14

Similar Documents

Publication Publication Date Title
ATE214938T1 (de) Feste, ein cyclosporin und ein anionisches netzmittel enthaltende arzneimittel
HUP0103793A3 (en) N-(2-aryl-propionyl)-sulfonamids, their use and pharmaceutical preparations containing them
ZA975533B (en) Cyclosporin-containing pharmaceutical composition.
DE60016602D1 (de) Zusammensetzung enthaltend ein tramadol und ein antikonvulsives arzneimittel
IL134293A0 (en) Linear peptides derived from antibiotic peptides, preparation and use for vectoring active substances
ATE300284T1 (de) Ein statin und aspirin enthaltendes arzneimittel
ZA969722B (en) Pharmaceutical formulations.
DE69737936D1 (de) Arzneimittel
BR9607851B1 (pt) combinaÇço e formulaÇço farmacÊutica.
ZA967546B (en) Pharmaceutical formulation.
NZ305735A (en) Cyclic peptide antifungal agents, preparation and pharmaceutical compositions thereof
ZA983849B (en) Pharmaceutical compositions of tizoxanide and nitazoxanide.
NO965102L (no) Bicykliske aromatiske forbindelser, anvendelser derav, og farmasöytiske og kosmetiske preparater
FI954986L (fi) Uudet, suun kautta annettavat, syklosporiinia sisältävät farmaseuttiset valmisteet
EP0960885A4 (de) Depsipeptide und medikamente, welche dieselben als aktive ingredienzien enthalten
HUP9903353A3 (en) 7alpha-(methyl-amino-pentyl)-estratrienes, pharmaceutical preparations which contain said 7alpha-(5-methylaminopentyl) -estratrienes and use thereof for production of drugs
DK0868911T3 (da) Rapamycinpræparater til oral indgivelse
GB9501286D0 (en) Pharmaceutical compositions and preparations thereof
ZA9710435B (en) Stabilized pharmaceutical compositions based on quinupristine and on dalfopristine and their preparation.
HUP0004661A3 (en) Polyhydroxybutylpyrazines, their preparation and medicines containing them
HUP0104623A3 (en) Cyclosporin solution, pharmaceutical composition comprising thereof and its use
HUP9602253A3 (en) Endothelin-receptor antagonists, pharmaceutical compositions containing the same and process for their preparations
IL128605A0 (en) Bottle for cosmetic and pharmaceutical products, hair dyes and the like, having separate components
DE69521347D1 (de) Ketonitrilderivate, antibaktrielle mittel und sie enthaltende arzneimittel
HUP0002821A3 (en) Polyhydroxyalkylpyrazine derivatives, preparation and medicines containing them

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties