ATE219356T1 - Lyophilisierte zubereitung sowie deren herstellung - Google Patents
Lyophilisierte zubereitung sowie deren herstellungInfo
- Publication number
- ATE219356T1 ATE219356T1 AT91918946T AT91918946T ATE219356T1 AT E219356 T1 ATE219356 T1 AT E219356T1 AT 91918946 T AT91918946 T AT 91918946T AT 91918946 T AT91918946 T AT 91918946T AT E219356 T1 ATE219356 T1 AT E219356T1
- Authority
- AT
- Austria
- Prior art keywords
- production
- lyophilized preparation
- emulsion
- preparation
- prior
- Prior art date
Links
- 238000002360 preparation method Methods 0.000 title abstract 3
- 238000004519 manufacturing process Methods 0.000 title abstract 2
- 239000000839 emulsion Substances 0.000 abstract 2
- OWEGMIWEEQEYGQ-UHFFFAOYSA-N 100676-05-9 Natural products OC1C(O)C(O)C(CO)OC1OCC1C(O)C(O)C(O)C(OC2C(OC(O)C(O)C2O)CO)O1 OWEGMIWEEQEYGQ-UHFFFAOYSA-N 0.000 abstract 1
- GUBGYTABKSRVRQ-PICCSMPSSA-N Maltose Natural products O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@@H]1O[C@@H]1[C@@H](CO)OC(O)[C@H](O)[C@H]1O GUBGYTABKSRVRQ-PICCSMPSSA-N 0.000 abstract 1
- 238000004108 freeze drying Methods 0.000 abstract 1
- 239000002960 lipid emulsion Substances 0.000 abstract 1
- 239000002245 particle Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
- A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- General Chemical & Material Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Dispersion Chemistry (AREA)
- Biophysics (AREA)
- Dermatology (AREA)
- Medicinal Preparation (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Colloid Chemistry (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP30163990 | 1990-11-06 | ||
| JP30164090 | 1990-11-06 | ||
| JP31205690 | 1990-11-16 | ||
| PCT/JP1991/001509 WO1992007552A1 (fr) | 1990-11-06 | 1991-11-05 | Preparation lyophilisee et sa production |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE219356T1 true ATE219356T1 (de) | 2002-07-15 |
Family
ID=27338476
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT91918946T ATE219356T1 (de) | 1990-11-06 | 1991-11-05 | Lyophilisierte zubereitung sowie deren herstellung |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US5635491A (de) |
| EP (1) | EP0556394B1 (de) |
| KR (1) | KR0154343B1 (de) |
| AT (1) | ATE219356T1 (de) |
| AU (1) | AU665931B2 (de) |
| CA (1) | CA2095627C (de) |
| DE (1) | DE69133042T2 (de) |
| ES (1) | ES2177522T3 (de) |
| HU (1) | HU217808B (de) |
| WO (1) | WO1992007552A1 (de) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5250236A (en) † | 1991-08-05 | 1993-10-05 | Gasco Maria R | Method for producing solid lipid microspheres having a narrow size distribution |
| DE4244122C1 (de) * | 1992-12-24 | 1994-06-01 | Sanol Arznei Schwarz Gmbh | Lyophilisierte, wirkstoffhaltige Emulsion zur intravenösen Applikation |
| US5977172A (en) * | 1995-09-13 | 1999-11-02 | Nippon Shinyaku Co., Ltd. | PGE1 -containing-freeze dried preparation and process for the production thereof |
| US6537561B1 (en) | 1997-02-27 | 2003-03-25 | Nippon Shinyaku Co., Ltd. | Fat emulsion for oral administration |
| KR20010041623A (ko) * | 1998-03-05 | 2001-05-25 | 니뽄 신야쿠 가부시키가이샤 | 흡입 투여용 지방 유제 |
| ID25649A (id) | 1998-03-09 | 2000-10-19 | Takeda Chemical Industries Ltd | Turunan-turunan sikloalkena, produksi serta penggunaannya |
| US7732404B2 (en) * | 1999-12-30 | 2010-06-08 | Dexcel Ltd | Pro-nanodispersion for the delivery of cyclosporin |
| GB0008785D0 (en) * | 2000-04-10 | 2000-05-31 | Novartis Ag | Organic compounds |
| US7960416B2 (en) * | 2001-08-03 | 2011-06-14 | Takeda Pharmaceutical Company Limited | Stable emulsion composition |
| US20050208083A1 (en) * | 2003-06-04 | 2005-09-22 | Nanobio Corporation | Compositions for inactivating pathogenic microorganisms, methods of making the compositons, and methods of use thereof |
| US8557861B2 (en) * | 2004-09-28 | 2013-10-15 | Mast Therapeutics, Inc. | Low oil emulsion compositions for delivering taxoids and other insoluble drugs |
| RU2304430C2 (ru) | 2005-08-12 | 2007-08-20 | Александр Иванович Арчаков | Способ получения инъекционной лекарственной формы фосфолипидного препарата "фосфоглив" для лечения и профилактики острых и хронических заболеваний печени |
| RU2304431C2 (ru) * | 2005-08-12 | 2007-08-20 | Александр Иванович Арчаков | Способ получения капсулированной лекарственной формы фосфолипидного препарата "фосфоглив" для лечения и профилактики острых и хронических заболеваний печени |
| TWI376239B (en) * | 2006-02-01 | 2012-11-11 | Andrew Xian Chen | Vitamin e succinate stabilized pharmaceutical compositions, methods for the preparation and the use thereof |
| PT2076244T (pt) * | 2006-10-10 | 2017-03-09 | Jina Pharmaceuticals Inc | Sistemas aquosos para a preparação de compostos farmacêuticos à base de lípidos; composições, métodos e utilizações dos mesmos |
| RU2411942C2 (ru) | 2009-05-05 | 2011-02-20 | Общество с ограниченной ответственностью "ЭкоБиоФарм" | Фармацевтическая композиция, включающая арбидол в составе фосфолипидных наночастиц |
| ES2657686T3 (es) | 2009-06-24 | 2018-03-06 | Lipoid Gmbh | Composición para aplicaciones cosméticas, farmacéuticas o dietéticas |
| CN102391342B (zh) * | 2011-09-20 | 2012-11-21 | 海南灵康制药有限公司 | 一种地塞米松棕榈酸酯化合物及其制法 |
| GR20120100181A (el) * | 2012-03-28 | 2013-10-15 | Μαριαννα Αχιλλεα Παπαμιχαηλ | Νεες λυοφιλοποιημενες φαρμακοτεχνικες και καλυντικοτεχνικες μορφες λυοφιλοποιημενων γαλακτωματων |
| US9492548B2 (en) * | 2012-12-14 | 2016-11-15 | Intervet Inc. | Emulsion containing a non-live medicinal substance |
| IL246456B2 (en) * | 2013-12-31 | 2024-06-01 | Access To Advanced Health Inst | Formulations will be assembled into a single vial |
| JP2020508350A (ja) * | 2017-02-21 | 2020-03-19 | アイシーオー セラピューティクス インコーポレイテッド | アンホテリシンｂの固体経口製剤 |
| CN109394704B (zh) * | 2018-11-27 | 2021-09-17 | 西安力邦肇新生物科技有限公司 | 一种前列腺素e1甲酯注射用冻干制剂及制备和应用 |
| US11992483B2 (en) * | 2021-03-31 | 2024-05-28 | Cali Biosciences Us, Llc | Emulsions for local anesthetics |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4102999A (en) * | 1975-02-10 | 1978-07-25 | Zaidan Hojin Biseibutsu Kagaku Kenkyu Kai | Process for producing stable macromomycin powder |
| JPS5924132B2 (ja) * | 1980-12-02 | 1984-06-07 | 株式会社 林原生物化学研究所 | 栄養補給用乳剤の製法 |
| JPS601123A (ja) * | 1983-06-17 | 1985-01-07 | Dai Ichi Seiyaku Co Ltd | 外用製剤 |
| JPS6045514A (ja) * | 1983-08-22 | 1985-03-12 | Shionogi & Co Ltd | 安定な抗菌性凍結乾燥製剤 |
| JPH0647533B2 (ja) * | 1984-08-10 | 1994-06-22 | 裕 水島 | ４−ビフエニリル酢酸系化合物含有脂肪乳剤 |
| FR2581543B1 (fr) * | 1985-05-09 | 1989-07-07 | Tressens Dominique | Pharmacotechnie permettant la realisation d'une preparation insulinique active par voie orale |
| IL78930A0 (en) * | 1985-07-29 | 1986-09-30 | Abbott Lab | Lyophilized emulsion compositions for parenteral administration |
| IL78929A0 (en) * | 1985-07-29 | 1986-09-30 | Abbott Lab | Microemulsion compositions for parenteral administration |
| JPH0798740B2 (ja) * | 1987-10-28 | 1995-10-25 | 日本新薬株式会社 | 薬物担体 |
| IL88076A (en) * | 1987-10-28 | 1993-01-14 | Nippon Shinyaku Co Ltd | Fat emulsions as drug carriers |
| JP2734520B2 (ja) * | 1988-03-29 | 1998-03-30 | 大正製薬株式会社 | 微粒子脂肪乳剤 |
-
1991
- 1991-11-05 CA CA002095627A patent/CA2095627C/en not_active Expired - Fee Related
- 1991-11-05 EP EP91918946A patent/EP0556394B1/de not_active Expired - Lifetime
- 1991-11-05 HU HU9301323A patent/HU217808B/hu not_active IP Right Cessation
- 1991-11-05 DE DE69133042T patent/DE69133042T2/de not_active Expired - Fee Related
- 1991-11-05 ES ES91918946T patent/ES2177522T3/es not_active Expired - Lifetime
- 1991-11-05 KR KR1019930701344A patent/KR0154343B1/ko not_active Expired - Fee Related
- 1991-11-05 WO PCT/JP1991/001509 patent/WO1992007552A1/ja not_active Ceased
- 1991-11-05 AT AT91918946T patent/ATE219356T1/de not_active IP Right Cessation
- 1991-11-05 AU AU87667/91A patent/AU665931B2/en not_active Ceased
- 1991-11-05 US US08/050,216 patent/US5635491A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| ES2177522T3 (es) | 2002-12-16 |
| CA2095627A1 (en) | 1992-05-07 |
| DE69133042D1 (de) | 2002-07-25 |
| AU665931B2 (en) | 1996-01-25 |
| HU9301323D0 (en) | 1993-09-28 |
| DE69133042T2 (de) | 2003-01-30 |
| WO1992007552A1 (fr) | 1992-05-14 |
| HUT64864A (en) | 1994-03-28 |
| US5635491A (en) | 1997-06-03 |
| EP0556394B1 (de) | 2002-06-19 |
| KR0154343B1 (ko) | 1998-11-16 |
| EP0556394A1 (de) | 1993-08-25 |
| CA2095627C (en) | 1999-01-05 |
| HU217808B (hu) | 2000-04-28 |
| EP0556394A4 (de) | 1994-03-17 |
| AU8766791A (en) | 1992-05-26 |
| KR930701972A (ko) | 1993-09-08 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |