ATE223576T1 - Methode zur identifizierung von verbindungen mit anxiolytischem potential - Google Patents

Methode zur identifizierung von verbindungen mit anxiolytischem potential

Info

Publication number
ATE223576T1
ATE223576T1 AT97909212T AT97909212T ATE223576T1 AT E223576 T1 ATE223576 T1 AT E223576T1 AT 97909212 T AT97909212 T AT 97909212T AT 97909212 T AT97909212 T AT 97909212T AT E223576 T1 ATE223576 T1 AT E223576T1
Authority
AT
Austria
Prior art keywords
identifying compounds
anxiolytic potential
ligands
cloned
gabaa receptor
Prior art date
Application number
AT97909212T
Other languages
English (en)
Inventor
Leif Helth Jensen
Tina Holm Johansen
Original Assignee
Neurosearch As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Neurosearch As filed Critical Neurosearch As
Application granted granted Critical
Publication of ATE223576T1 publication Critical patent/ATE223576T1/de

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/94—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving narcotics or drugs or pharmaceuticals, neurotransmitters or associated receptors
    • G01N33/9406—Neurotransmitters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Food Science & Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Elimination Of Static Electricity (AREA)
AT97909212T 1996-10-25 1997-10-27 Methode zur identifizierung von verbindungen mit anxiolytischem potential ATE223576T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DK118296 1996-10-25
PCT/DK1997/000475 WO1998019165A1 (en) 1996-10-25 1997-10-27 A method for the identification of compounds with anxiolytic potential

Publications (1)

Publication Number Publication Date
ATE223576T1 true ATE223576T1 (de) 2002-09-15

Family

ID=8101912

Family Applications (1)

Application Number Title Priority Date Filing Date
AT97909212T ATE223576T1 (de) 1996-10-25 1997-10-27 Methode zur identifizierung von verbindungen mit anxiolytischem potential

Country Status (5)

Country Link
EP (1) EP0934528B1 (de)
JP (1) JP3868502B2 (de)
AT (1) ATE223576T1 (de)
DE (1) DE69715231T2 (de)
WO (1) WO1998019165A1 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6737242B1 (en) 1999-05-07 2004-05-18 Neurogen Corporation Methods for screening GABA-modulatory compounds for specified pharmacological activities
CA2371219A1 (en) * 1999-05-07 2000-11-16 Neurogen Corporation Methods for screening gaba-modulatory compounds for specified pharmacological activities
JP2004510789A (ja) * 2000-10-05 2004-04-08 モーラー，ハンス 選択的抗不安治療薬

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5166066A (en) * 1991-07-11 1992-11-24 The Upjohn Company Transformed cells comprising GABAA receptors
US5597920A (en) * 1992-04-30 1997-01-28 Neurogen Corporation Gabaa receptor subtypes and methods for screening drug compounds using imidazoquinoxalines and pyrrolopyrimidines to bind to gabaa receptor subtypes
DE69333923T2 (de) * 1992-12-10 2006-08-03 Merck Sharp & Dohme Ltd., Hoddesdon Stabil transfizierte Zelllinien welche Gaba-A- Rezeptoren mit der Untereinheitenzusammensetzung alpha-3, beta-3 und gamma-2 exprimieren
BR9608056A (pt) * 1995-04-21 1999-11-30 Neurosearch As Compostos de benzimidazol, composições farmacêuticas contendo os compostos e sua utilização.

Also Published As

Publication number Publication date
EP0934528B1 (de) 2002-09-04
JP3868502B2 (ja) 2007-01-17
DE69715231T2 (de) 2003-05-22
DE69715231D1 (de) 2002-10-10
WO1998019165A1 (en) 1998-05-07
JP2001505661A (ja) 2001-04-24
EP0934528A1 (de) 1999-08-11

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