ATE226446T1 - Muteine von wildtyp-cytokinen und ihre verwendung als immunogene - Google Patents

Muteine von wildtyp-cytokinen und ihre verwendung als immunogene

Info

Publication number
ATE226446T1
ATE226446T1 AT96930345T AT96930345T ATE226446T1 AT E226446 T1 ATE226446 T1 AT E226446T1 AT 96930345 T AT96930345 T AT 96930345T AT 96930345 T AT96930345 T AT 96930345T AT E226446 T1 ATE226446 T1 AT E226446T1
Authority
AT
Austria
Prior art keywords
cytokines
muteins
immunogens
wild
type cytokines
Prior art date
Application number
AT96930345T
Other languages
English (en)
Inventor
Gennaro Ciliberto
Rocco Savino
Riccardo Cortese
Original Assignee
Angeletti P Ist Richerche Bio
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Angeletti P Ist Richerche Bio filed Critical Angeletti P Ist Richerche Bio
Application granted granted Critical
Publication of ATE226446T1 publication Critical patent/ATE226446T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0005—Vertebrate antigens
    • A61K39/0008—Antigens related to auto-immune diseases; Preparations to induce self-tolerance
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55505—Inorganic adjuvants

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Immunology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Rheumatology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Noise Elimination (AREA)
AT96930345T 1995-09-01 1996-08-22 Muteine von wildtyp-cytokinen und ihre verwendung als immunogene ATE226446T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT95RM000589A IT1277926B1 (it) 1995-09-01 1995-09-01 Uso di muteine di citochine naturali come immunogeni per la preparazione di composizioni farmaceutiche per curare o prevenire
PCT/IT1996/000164 WO1997009064A1 (en) 1995-09-01 1996-08-22 Use of muteins of wild-type cytokines as immunogens

Publications (1)

Publication Number Publication Date
ATE226446T1 true ATE226446T1 (de) 2002-11-15

Family

ID=11403544

Family Applications (1)

Application Number Title Priority Date Filing Date
AT96930345T ATE226446T1 (de) 1995-09-01 1996-08-22 Muteine von wildtyp-cytokinen und ihre verwendung als immunogene

Country Status (16)

Country Link
US (1) US6706261B1 (de)
EP (1) EP0858345B1 (de)
JP (1) JP3157837B2 (de)
KR (1) KR100279539B1 (de)
CN (1) CN1138562C (de)
AT (1) ATE226446T1 (de)
AU (1) AU703300B2 (de)
CA (1) CA2229045C (de)
DE (1) DE69624498T2 (de)
DK (1) DK0858345T3 (de)
ES (1) ES2183007T3 (de)
IT (1) IT1277926B1 (de)
MX (1) MX9801550A (de)
PT (1) PT858345E (de)
RU (1) RU2182014C2 (de)
WO (1) WO1997009064A1 (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU7645700A (en) * 1999-10-07 2001-05-10 Maxygen Aps Single-chain antagonist polypeptides
FR2812813B1 (fr) * 2000-08-09 2004-11-26 Neovacs Utilisation d'immunogenes pour traiter ou prevenir au sein des tumeurs malignes les dereglements immunitaires induits par des facteurs extracellulaires
FR2838444B1 (fr) * 2002-04-10 2016-01-01 Neovacs Nouveaux peptides et leur application en therapeutique
IL161672A0 (en) * 2004-04-29 2004-09-27 Yeda Res & Dev Compositions and methods for therapy of chemotherapy-induced neuropathy
FR2978964B1 (fr) 2011-08-09 2015-02-20 Conservatoire Nat Arts Composition vaccinale anti-il-6
WO2015024148A1 (zh) * 2013-08-23 2015-02-26 中国科学院微生物研究所 异源动物细胞因子突变体疫苗

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2677654B1 (fr) 1991-06-17 1995-11-17 Pasteur Merieux Serums Vacc Composes a effet immunogene anti-cytokine, a effet immunogene anticytostatique ou a effet vaccinal anti-infection a hiv.
US5338833A (en) * 1992-07-23 1994-08-16 The University Of North Carolina At Chapel Hill Carboxy terminal IL-6 muteins
IT1263022B (it) * 1992-11-06 1996-07-23 Angeletti P Ist Richerche Bio Interleuchina-6 mutante con attivita' biologica migliorata rispetto all'interleuchina-6 selvatica.
IT1261787B (it) * 1993-06-23 1996-06-03 Angeletti P Ist Richerche Bio Metodologia per la selezione di superagonisti, antagonisti e super- antagonisti di ormoni del cui complesso recettoriale fa parte gp 130.
WO1997010338A1 (en) 1995-09-12 1997-03-20 Chiron Corporation Improved interleukin-6 receptor antagonist

Also Published As

Publication number Publication date
KR100279539B1 (ko) 2001-02-01
US6706261B1 (en) 2004-03-16
AU703300B2 (en) 1999-03-25
CN1198098A (zh) 1998-11-04
DE69624498D1 (de) 2002-11-28
KR19990044321A (ko) 1999-06-25
RU2182014C2 (ru) 2002-05-10
IT1277926B1 (it) 1997-11-12
DK0858345T3 (da) 2003-02-24
ITRM950589A0 (it) 1995-09-01
CN1138562C (zh) 2004-02-18
WO1997009064A1 (en) 1997-03-13
PT858345E (pt) 2003-02-28
ITRM950589A1 (it) 1997-03-01
ES2183007T3 (es) 2003-03-16
HK1015708A1 (en) 1999-10-22
CA2229045A1 (en) 1997-03-13
JP3157837B2 (ja) 2001-04-16
MX9801550A (es) 1998-05-31
CA2229045C (en) 2005-10-25
DE69624498T2 (de) 2003-06-18
AU6942896A (en) 1997-03-27
EP0858345B1 (de) 2002-10-23
JPH10511111A (ja) 1998-10-27
EP0858345A1 (de) 1998-08-19

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