ZA971023B - Quinolonecarboxylic acid derivatives or their salts. - Google Patents

Quinolonecarboxylic acid derivatives or their salts.

Info

Publication number: ZA971023B
Authority: ZA; South Africa
Prior art keywords: salts; optionally substituted; acid derivatives; halogeno; lower alkyl
Prior art date: 1996-02-09

Application number

ZA9701023A

Other languages

English (en)

Inventor

Yozo Todo

Kazuya Hayashi

Masahiro Takahata

Yasuo Watanabe

Hirokazu Narita

Original Assignee

Toyama Chemical Co Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-02-09

Filing date

1997-02-07

Publication date

1997-09-25

1997-02-07 Application filed by Toyama Chemical Co Ltd filed Critical Toyama Chemical Co Ltd

1997-09-25 Publication of ZA971023B publication Critical patent/ZA971023B/xx

Links

150000003839 salts Chemical class 0.000 title abstract 2
XOQQVKDBGLYPGH-UHFFFAOYSA-N 2-oxo-1h-quinoline-3-carboxylic acid Chemical class C1=CC=C2NC(=O)C(C(=O)O)=CC2=C1 XOQQVKDBGLYPGH-UHFFFAOYSA-N 0.000 title 1
125000000217 alkyl group Chemical group 0.000 abstract 3
125000005843 halogen group Chemical group 0.000 abstract 3
229910052739 hydrogen Inorganic materials 0.000 abstract 3
239000001257 hydrogen Substances 0.000 abstract 3
125000003545 alkoxy group Chemical group 0.000 abstract 2
150000002431 hydrogen Chemical class 0.000 abstract 2
125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 2
UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
239000002253 acid Substances 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
125000005346 substituted cycloalkyl group Chemical group 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/475—Quinolines; Isoquinolines having an indole ring, e.g. yohimbine, reserpine, strychnine, vinblastine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
- C07F5/02—Boron compounds
- C07F5/025—Boronic and borinic acid compounds

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Quinoline Compounds (AREA)
Indole Compounds (AREA)

ZA9701023A 1996-02-09 1997-02-07 Quinolonecarboxylic acid derivatives or their salts. ZA971023B (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
JP4793696		1996-02-09

Publications (1)

Publication Number	Publication Date
ZA971023B true ZA971023B (en)	1997-09-25

Family

ID=12789268

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ZA9701023A ZA971023B (en)	1996-02-09	1997-02-07	Quinolonecarboxylic acid derivatives or their salts.

Country Status (18)

Country	Link
US (1)	US6025370A (de)
EP (1)	EP0882725B1 (de)
KR (1)	KR100276477B1 (de)
CN (2)	CN1100053C (de)
AT (1)	ATE229950T1 (de)
AU (1)	AU711914B2 (de)
CA (1)	CA2242242C (de)
DE (1)	DE69717970T2 (de)
DK (1)	DK0882725T3 (de)
ES (1)	ES2188890T3 (de)
HK (1)	HK1039118B (de)
HU (1)	HU228567B1 (de)
IL (1)	IL124944A (de)
NO (1)	NO316666B1 (de)
NZ (1)	NZ330775A (de)
PT (1)	PT882725E (de)
WO (1)	WO1997029102A1 (de)
ZA (1)	ZA971023B (de)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
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US6387928B1 (en)	1997-09-15	2002-05-14	The Procter & Gamble Co.	Antimicrobial quinolones, their compositions and uses
CN1264837C (zh)	1997-09-15	2006-07-19	普罗克特和甘保尔公司	喹诺酮抗微生物剂、其组合物和应用
ES2341509T3 (es) *	1997-10-27	2010-06-21	Toyama Chemical Co., Ltd.	Sal de un derivado de acido 7-isoindolino-quinoloncarboxilico, su monohidrato y composiciones que lo contienen como ingredientes activos.
JP3281872B2 (ja)	1998-03-20	2002-05-13	富山化学工業株式会社	７−イソインドリン−３−キノリンカルボン酸の塩、その水和物およびそれらを活性成分とする組成物
ATE342897T1 (de) *	1998-04-06	2006-11-15	Toyama Chemical Co Ltd	Chinoloncarbonsäurederivate oder deren salze
JP4499846B2 (ja) *	1998-05-07	2010-07-07	富山化学工業株式会社	７−イソインドリン−キノロンカルボン酸誘導体の製造法並びにイソインドリン−５−ボロン酸誘導体の製造法
JP4549461B2 (ja) *	1998-08-31	2010-09-22	富山化学工業株式会社	７−ブロモ−キノロンカルボン酸誘導体の製造法
JP2000229946A (ja) *	1998-12-10	2000-08-22	Toyama Chem Co Ltd	キノロンカルボン酸の製造法およびその中間体
HK1044476B (zh)	1999-03-17	2010-09-17	第一制药株式会社	药物组合物
MXPA04008720A (es) *	2002-03-12	2004-12-06	Squibb Bristol Myers Co	Suspension oral de sabor agradable y metodo.
US7626029B2 (en)	2003-06-19	2009-12-01	Daiichi Pharmaceutical Co., Ltd.	Method of selectively introducing amino substituent
DE10337191A1 (de) *	2003-08-13	2005-03-17	Bayer Healthcare Ag	Neue Verwendung von Chinolon-Antibiotika
KR100981351B1 (ko) *	2003-10-29	2010-09-10	주식회사 엘지생명과학	7-클로로-1-사이클로프로필-6-플루오로-4-옥소-1,4-디하이드로-1,8-나프티리딘-3-카복실산의 제조방법
US20090156577A1 (en) *	2004-09-09	2009-06-18	Benjamin Davis	7-amino alkylidenyl-heterocyclic quinolones and naphthyridones
WO2006093189A1 (ja) *	2005-03-03	2006-09-08	Chisso Corporation	クロロフルオロベンゼン系液晶性化合物、液晶組成物および液晶表示素子
CA2647454A1 (en)	2006-03-28	2007-10-04	The Procter & Gamble Company	A coupling process for preparing quinolone intermediates
BRPI0709209A2 (pt)	2006-03-28	2011-06-28	Procter & Gamble	processo de redução de hidreto para preparo de intermediários de quinolona
US7902227B2 (en)	2007-07-27	2011-03-08	Janssen Pharmaceutica Nv.	C-7 isoxazolinyl quinolone / naphthyridine derivatives useful as antibacterial agents
CN101298418B (zh) *	2008-06-13	2010-12-15	江苏康鹏农化有限公司	3-氧代-3-(2,4-二卤代-3-二氟甲氧基苯基)丙酸乙酯的制备方法
CN102212056A (zh) *	2010-04-09	2011-10-12	山东轩竹医药科技有限公司	新的双环喹诺酮类化合物
WO2013121439A2 (en) *	2012-02-15	2013-08-22	Glenmark Generics Limited	Process for garenoxacin mesylate
WO2014152332A1 (en)	2013-03-15	2014-09-25	Melinta Therapeutics, Inc.	Methods of treating infections in overweight and obese patients using antibiotics
GB201516614D0 (en) *	2015-09-18	2015-11-04	Redx Pharma Plc	Antibacterial compounds
CN105837555B (zh) *	2016-03-31	2019-01-25	南京华威医药科技集团有限公司	加雷沙星及其中间体制备方法
CN111620901B (zh) *	2020-06-08	2023-03-21	蚌埠医学院第二附属医院	一种含硅氧烷基的氟喹诺酮化合物、其制备方法及用途

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS6199835A (ja) *	1984-10-22	1986-05-17	Shimadzu Corp	振動試験機の波形補正装置
IL90062A (en) *	1988-04-27	1994-10-07	Daiichi Seiyaku Co	Pyridonecarboxylic acid derivatives, their preparation and pharmaceutical compositions containing them
PL166381B1 (pl) *	1989-08-16	1995-05-31	Pfizer	Sposób wytwarzania nowych podstawionych kwasów 7-azabicyklochinolonokarboksylowych PL PL PL PL
EG20543A (en) *	1992-10-30	1999-07-31	Procter & Gamble	Process for preparing of novel antimicrobial -5- (n-heterosubstituted amino) quinolones
JPH07300472A (ja) *	1992-12-28	1995-11-14	Korea Res Inst Chem Technol	新規キノロンカルボン酸誘導体およびその製造方法
JPH06199835A (ja) *	1993-01-08	1994-07-19	Hokuriku Seiyaku Co Ltd	８−ジフルオロメトキシキノリン−３−カルボン酸誘導体
DE4301246A1 (de) *	1993-01-19	1994-07-21	Bayer Ag	Chinolon- und Naphthyridoncarbonsäurederivate
JPH0848629A (ja) *	1994-08-08	1996-02-20	Dainippon Pharmaceut Co Ltd	ピリドンカルボン酸誘導体およびそれを有効成分とする抗ピロリ菌剤
NZ290946A (en) *	1994-08-12	1997-12-19	Toyama Chemical Co Ltd	Quinolone- or naphthyridone-carboxylic acid derivatives

1997
- 1997-02-07 KR KR1019980706138A patent/KR100276477B1/ko not_active Expired - Lifetime
- 1997-02-07 WO PCT/JP1997/000317 patent/WO1997029102A1/ja not_active Ceased
- 1997-02-07 HU HU9901966A patent/HU228567B1/hu unknown
- 1997-02-07 PT PT97902618T patent/PT882725E/pt unknown
- 1997-02-07 CN CN97192130A patent/CN1100053C/zh not_active Expired - Lifetime
- 1997-02-07 EP EP97902618A patent/EP0882725B1/de not_active Expired - Lifetime
- 1997-02-07 ZA ZA9701023A patent/ZA971023B/xx unknown
- 1997-02-07 CA CA002242242A patent/CA2242242C/en not_active Expired - Lifetime
- 1997-02-07 AT AT97902618T patent/ATE229950T1/de active
- 1997-02-07 CN CNB011012323A patent/CN100395244C/zh not_active Expired - Lifetime
- 1997-02-07 AU AU16701/97A patent/AU711914B2/en not_active Expired
- 1997-02-07 US US09/125,016 patent/US6025370A/en not_active Expired - Lifetime
- 1997-02-07 ES ES97902618T patent/ES2188890T3/es not_active Expired - Lifetime
- 1997-02-07 DE DE69717970T patent/DE69717970T2/de not_active Expired - Lifetime
- 1997-02-07 NZ NZ330775A patent/NZ330775A/xx not_active IP Right Cessation
- 1997-02-07 IL IL12494497A patent/IL124944A/xx not_active IP Right Cessation
- 1997-02-07 DK DK97902618T patent/DK0882725T3/da active
1998
- 1998-08-07 NO NO19983625A patent/NO316666B1/no not_active IP Right Cessation
2002
- 2002-01-16 HK HK02100336.1A patent/HK1039118B/zh not_active IP Right Cessation

Also Published As

Publication number	Publication date
AU711914B2 (en)	1999-10-21
IL124944A0 (en)	1999-01-26
EP0882725A1 (de)	1998-12-09
HK1039118B (zh)	2009-01-30
HU228567B1 (en)	2013-04-29
HK1039118A1 (zh)	2002-04-12
NO983625L (no)	1998-08-07
KR100276477B1 (ko)	2000-12-15
CN1314355A (zh)	2001-09-26
PT882725E (pt)	2003-04-30
US6025370A (en)	2000-02-15
ES2188890T3 (es)	2003-07-01
ATE229950T1 (de)	2003-01-15
KR19990082406A (ko)	1999-11-25
CN1100053C (zh)	2003-01-29
CN1210533A (zh)	1999-03-10
CN100395244C (zh)	2008-06-18
DE69717970D1 (de)	2003-01-30
HUP9901966A2 (hu)	1999-09-28
NO316666B1 (no)	2004-03-29
WO1997029102A1 (en)	1997-08-14
NZ330775A (en)	1999-08-30
DE69717970T2 (de)	2003-04-30
DK0882725T3 (da)	2003-01-13
EP0882725A4 (de)	1999-05-06
AU1670197A (en)	1997-08-28
EP0882725B1 (de)	2002-12-18
IL124944A (en)	2003-06-24
CA2242242C (en)	2001-08-07
HUP9901966A3 (en)	2002-01-28
CA2242242A1 (en)	1997-08-14
NO983625D0 (no)	1998-08-07

Publication	Publication Date	Title
IL124944A0 (en)	1999-01-26	Quinolonecarboxylic acid derivatives or their salts
PT1043317E (pt)	2009-05-11	Novos derivados de piridazina e fármacos que os contêm como ingrediente activo
EP0900795A4 (de)	2000-12-13	Heterocyclisch substituierte benzolderivate und herbizide
AU1282495A (en)	1995-07-17	Anthranilic acid derivative
PL334915A1 (en)	2000-03-27	Pyrrolidine derivatives exhibiting phospholipase a2 inhibiting activity
AU9281198A (en)	1999-04-23	Benzofuran derivatives
DK0695755T3 (da)	1999-06-28	Pyrrolocarbazoler
FR15C0027I2 (fr)	2016-04-15	Derives de pyrazolinone
TW271440B (de)	1996-03-01
AU2044697A (en)	1997-10-29	Phenylalkylcarboxylic acid derivatives
AU696948B2 (en)	1998-09-24	Piperidine derivatives
DE69706950D1 (de)	2001-10-31	Furoindolizine
EP0978281A4 (de)	2000-06-21	Augentropfen
ATE171622T1 (de)	1998-10-15	Antiallergische zusammensetzung enthaltend eine phosphorsäurediester-verbindung
EP0573659A4 (en)	1994-09-07	Pyrazolothiazolopyrimidine derivative
EP0994111A4 (de)	2001-01-24	Tetrahydrofuranderivate