ATE229964T1 - Calcium (3s) tetrahydro-3-furanyl(1s,2r)-3-(((4- aminophenyl) sulfonyl)(isobutyl)amino)-1-benzyl-2-(phosphono xy)propylcarbamat - Google Patents

Calcium (3s) tetrahydro-3-furanyl(1s,2r)-3-(((4- aminophenyl) sulfonyl)(isobutyl)amino)-1-benzyl-2-(phosphono xy)propylcarbamat

Info

Publication number
ATE229964T1
ATE229964T1 AT99934698T AT99934698T ATE229964T1 AT E229964 T1 ATE229964 T1 AT E229964T1 AT 99934698 T AT99934698 T AT 99934698T AT 99934698 T AT99934698 T AT 99934698T AT E229964 T1 ATE229964 T1 AT E229964T1
Authority
AT
Austria
Prior art keywords
carbamat
phosphono
aminophenyl
furanyl
tetrahydro
Prior art date
Application number
AT99934698T
Other languages
English (en)
Inventor
Ian Gordon Armitage
Andrew David Searle
Hardev Singh
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Application granted granted Critical
Publication of ATE229964T1 publication Critical patent/ATE229964T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/655—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/655—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms
    • C07F9/65515—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms the oxygen atom being part of a five-membered ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/665—Phosphorus compounds having oxygen as a ring hetero atom, e.g. fosfomycin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Virology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • AIDS & HIV (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT99934698T 1998-07-18 1999-07-15 Calcium (3s) tetrahydro-3-furanyl(1s,2r)-3-(((4- aminophenyl) sulfonyl)(isobutyl)amino)-1-benzyl-2-(phosphono xy)propylcarbamat ATE229964T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9815567.4A GB9815567D0 (en) 1998-07-18 1998-07-18 Antiviral compound
PCT/EP1999/004991 WO2000004033A1 (en) 1998-07-18 1999-07-15 Calcium (3s) tetrahydro-3-furanyl(1s,2r)-3-[[(4-aminophenyl) sulfonyl] (isobutyl) amino] -1-benzyl-2- (phosphonooxy) propylcarbamate

Publications (1)

Publication Number Publication Date
ATE229964T1 true ATE229964T1 (de) 2003-01-15

Family

ID=10835689

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99934698T ATE229964T1 (de) 1998-07-18 1999-07-15 Calcium (3s) tetrahydro-3-furanyl(1s,2r)-3-(((4- aminophenyl) sulfonyl)(isobutyl)amino)-1-benzyl-2-(phosphono xy)propylcarbamat

Country Status (47)

Country Link
US (3) US6514953B1 (de)
EP (2) EP1098898B1 (de)
JP (1) JP3437553B2 (de)
KR (1) KR100694721B1 (de)
CN (1) CN1188422C (de)
AP (1) AP2001002039A0 (de)
AR (1) AR019388A1 (de)
AT (1) ATE229964T1 (de)
AU (1) AU766056B2 (de)
BG (1) BG105253A (de)
BR (1) BRPI9912156B8 (de)
CA (1) CA2337857C (de)
CO (1) CO5090836A1 (de)
CZ (1) CZ300447B6 (de)
DE (1) DE69904600T2 (de)
DK (1) DK1098898T3 (de)
DZ (1) DZ2845A1 (de)
EA (1) EA003191B1 (de)
EE (1) EE200100038A (de)
ES (1) ES2189450T3 (de)
GB (1) GB9815567D0 (de)
GC (1) GC0000105A (de)
GE (1) GEP20033030B (de)
GT (1) GT199900111A (de)
HR (1) HRP20010046A2 (de)
HU (1) HU229700B1 (de)
ID (1) ID28070A (de)
IL (1) IL140824A (de)
IS (1) IS5808A (de)
JO (1) JO2114B1 (de)
MA (1) MA26660A1 (de)
MY (1) MY122323A (de)
NO (1) NO329676B1 (de)
NZ (1) NZ509291A (de)
OA (1) OA11706A (de)
PA (1) PA8477801A1 (de)
PE (1) PE20000869A1 (de)
PL (1) PL195736B1 (de)
PT (1) PT1098898E (de)
SK (1) SK285311B6 (de)
SV (1) SV1999000096A (de)
TN (1) TNSN99145A1 (de)
TR (1) TR200100111T2 (de)
TW (1) TWI245770B (de)
WO (1) WO2000004033A1 (de)
YU (1) YU3401A (de)
ZA (1) ZA200100417B (de)

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PL1628685T3 (pl) 2003-04-25 2011-05-31 Gilead Sciences Inc Przeciwwirusowe analogi fosfonianowe
WO2004096287A2 (en) 2003-04-25 2004-11-11 Gilead Sciences, Inc. Inosine monophosphate dehydrogenase inhibitory phosphonate compounds
US7300924B2 (en) 2003-04-25 2007-11-27 Gilead Sciences, Inc. Anti-infective phosphonate analogs
JP2006524710A (ja) 2003-04-25 2006-11-02 ギリアード サイエンシーズ， インコーポレイテッド キナーゼインヒビターホスホネート抱合体
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US7432261B2 (en) 2003-04-25 2008-10-07 Gilead Sciences, Inc. Anti-inflammatory phosphonate compounds
US7407965B2 (en) 2003-04-25 2008-08-05 Gilead Sciences, Inc. Phosphonate analogs for treating metabolic diseases
US7470724B2 (en) 2003-04-25 2008-12-30 Gilead Sciences, Inc. Phosphonate compounds having immuno-modulatory activity
US7452901B2 (en) 2003-04-25 2008-11-18 Gilead Sciences, Inc. Anti-cancer phosphonate analogs
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UA105556C2 (uk) 2010-01-27 2014-05-26 Віів Гелскер Компані Комбінація сполук, що містить інгібітори віл інтегрази з іншими терапевтичними агентами
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JP6990170B2 (ja) 2015-08-18 2022-01-12 オセラ セラピューティクス， インコーポレイテッド Ｌ－オルニチンをフェニルアセテートおよびフェニルブチレートのうちの少なくとも１つと組み合わせて用いる筋肉喪失の治療および予防
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CN110740988A (zh) 2017-05-11 2020-01-31 欧塞拉治疗有限公司 制备l-鸟氨酸苯乙酸盐的方法
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Also Published As

Publication number Publication date
EP1240903A2 (de) 2002-09-18
PA8477801A1 (es) 2000-05-24
AP2001002039A0 (en) 2001-03-31
EP1098898A1 (de) 2001-05-16
MA26660A1 (fr) 2004-12-20
IS5808A (is) 2001-01-12
IL140824A0 (en) 2002-02-10
HRP20010046A2 (en) 2002-02-28
SK285311B6 (sk) 2006-10-05
GC0000105A (en) 2005-06-29
PL345620A1 (en) 2002-01-02
SV1999000096A (es) 2000-07-06
GT199900111A (es) 2001-01-05
NO20010282D0 (no) 2001-01-17
DE69904600T2 (de) 2003-11-13
EE200100038A (et) 2002-06-17
GB9815567D0 (en) 1998-09-16
US20030096795A1 (en) 2003-05-22
DK1098898T3 (da) 2003-04-07
EA200100053A1 (ru) 2001-08-27
CN1188422C (zh) 2005-02-09
JP2003521447A (ja) 2003-07-15
AU766056B2 (en) 2003-10-09
PL195736B1 (pl) 2007-10-31
ES2189450T3 (es) 2003-07-01
BG105253A (en) 2001-12-29
NO329676B1 (no) 2010-11-29
PE20000869A1 (es) 2000-09-08
DE69904600D1 (de) 2003-01-30
WO2000004033A1 (en) 2000-01-27
HUP0103432A3 (en) 2003-01-28
CA2337857A1 (en) 2000-01-27
NZ509291A (en) 2003-05-30
TNSN99145A1 (fr) 2005-11-10
KR100694721B1 (ko) 2007-03-15
BRPI9912156B1 (pt) 2016-07-26
IL140824A (en) 2004-09-27
PT1098898E (pt) 2003-04-30
TR200100111T2 (tr) 2002-02-21
CN1324363A (zh) 2001-11-28
ID28070A (id) 2001-05-03
BR9912156A (pt) 2001-04-10
HUP0103432A2 (hu) 2002-04-29
DZ2845A1 (fr) 2003-12-01
BRPI9912156B8 (pt) 2021-05-25
SK762001A3 (en) 2001-10-08
GEP20033030B (en) 2003-07-25
HK1034261A1 (en) 2001-10-19
EP1098898B1 (de) 2002-12-18
AR019388A1 (es) 2002-02-13
CO5090836A1 (es) 2001-10-30
CZ2001219A3 (cs) 2001-07-11
KR20010071952A (ko) 2001-07-31
US20030100537A1 (en) 2003-05-29
ZA200100417B (en) 2002-02-27
CZ300447B6 (cs) 2009-05-20
TWI245770B (en) 2005-12-21
JO2114B1 (en) 2000-05-21
EP1240903A3 (de) 2003-02-12
MY122323A (en) 2006-04-29
US6514953B1 (en) 2003-02-04
NO20010282L (no) 2001-03-07
EA003191B1 (ru) 2003-02-27
HU229700B1 (en) 2014-05-28
CA2337857C (en) 2011-01-25
JP3437553B2 (ja) 2003-08-18
AU5037999A (en) 2000-02-07
OA11706A (en) 2005-01-13
YU3401A (sh) 2005-06-10

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