DZ2845A1 - Calcium (3S) tétrahydro-3-furanyle(1S,2R)-3-ÄÄ(4-aminophényle)sulfonyleÜ(sobutyle)aminoÜ-1-benzyle-2(phosphonooxy)propylcarbamate. - Google Patents

Calcium (3S) tétrahydro-3-furanyle(1S,2R)-3-ÄÄ(4-aminophényle)sulfonyleÜ(sobutyle)aminoÜ-1-benzyle-2(phosphonooxy)propylcarbamate.

Info

Publication number: DZ2845A1
Authority: DZ; Algeria
Prior art keywords: sulfonylü; aminoü; sobutyl; propylcarbamate; phosphonooxy
Prior art date: 1998-07-18

Application number

DZ990145A

Other languages

English (en)

Inventor

Lan Cordon Armitage

Andrew David Sealle

Hardev Singh

Original Assignee

Glaxo Group Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-07-18

Filing date

1999-07-14

Publication date

2003-12-01

1999-07-14 Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd

2003-12-01 Application granted granted Critical

2003-12-01 Publication of DZ2845A1 publication Critical patent/DZ2845A1/fr

Links

OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 title 2
229910052791 calcium Inorganic materials 0.000 title 1
239000011575 calcium Substances 0.000 title 1
UKJLNMAFNRKWGR-UHFFFAOYSA-N cyclohexatrienamine Chemical group NC1=CC=C=C[CH]1 UKJLNMAFNRKWGR-UHFFFAOYSA-N 0.000 title 1
JUYJJVLZOXNPHW-UHFFFAOYSA-N phosphono N-propylcarbamoperoxoate Chemical compound C(CC)NC(OOP(=O)(O)O)=O JUYJJVLZOXNPHW-UHFFFAOYSA-N 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/655—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/655—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms
- C07F9/65515—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms the oxygen atom being part of a five-membered ring
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/665—Phosphorus compounds having oxygen as a ring hetero atom, e.g. fosfomycin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Virology (AREA)
Molecular Biology (AREA)
General Chemical & Material Sciences (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
Biochemistry (AREA)
Immunology (AREA)
Epidemiology (AREA)
Tropical Medicine & Parasitology (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
AIDS & HIV (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

DZ990145A 1998-07-18 1999-07-14 Calcium (3S) tétrahydro-3-furanyle(1S,2R)-3-ÄÄ(4-aminophényle)sulfonyleÜ(sobutyle)aminoÜ-1-benzyle-2(phosphonooxy)propylcarbamate. DZ2845A1 (fr)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GBGB9815567.4A GB9815567D0 (en)	1998-07-18	1998-07-18	Antiviral compound

Publications (1)

Publication Number	Publication Date
DZ2845A1 true DZ2845A1 (fr)	2003-12-01

Family

ID=10835689

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DZ990145A DZ2845A1 (fr)	1998-07-18	1999-07-14	Calcium (3S) tétrahydro-3-furanyle(1S,2R)-3-ÄÄ(4-aminophényle)sulfonyleÜ(sobutyle)aminoÜ-1-benzyle-2(phosphonooxy)propylcarbamate.

Country Status (47)

Country	Link
US (3)	US6514953B1 (fr)
EP (2)	EP1240903A3 (fr)
JP (1)	JP3437553B2 (fr)
KR (1)	KR100694721B1 (fr)
CN (1)	CN1188422C (fr)
AP (1)	AP2001002039A0 (fr)
AR (1)	AR019388A1 (fr)
AT (1)	ATE229964T1 (fr)
AU (1)	AU766056B2 (fr)
BG (1)	BG105253A (fr)
BR (1)	BRPI9912156B8 (fr)
CA (1)	CA2337857C (fr)
CO (1)	CO5090836A1 (fr)
CZ (1)	CZ300447B6 (fr)
DE (1)	DE69904600T2 (fr)
DK (1)	DK1098898T3 (fr)
DZ (1)	DZ2845A1 (fr)
EA (1)	EA003191B1 (fr)
EE (1)	EE200100038A (fr)
ES (1)	ES2189450T3 (fr)
GB (1)	GB9815567D0 (fr)
GC (1)	GC0000105A (fr)
GE (1)	GEP20033030B (fr)
GT (1)	GT199900111A (fr)
HR (1)	HRP20010046A2 (fr)
HU (1)	HU229700B1 (fr)
ID (1)	ID28070A (fr)
IL (1)	IL140824A (fr)
IS (1)	IS5808A (fr)
JO (1)	JO2114B1 (fr)
MA (1)	MA26660A1 (fr)
MY (1)	MY122323A (fr)
NO (1)	NO329676B1 (fr)
NZ (1)	NZ509291A (fr)
OA (1)	OA11706A (fr)
PA (1)	PA8477801A1 (fr)
PE (1)	PE20000869A1 (fr)
PL (1)	PL195736B1 (fr)
PT (1)	PT1098898E (fr)
SK (1)	SK285311B6 (fr)
SV (1)	SV1999000096A (fr)
TN (1)	TNSN99145A1 (fr)
TR (1)	TR200100111T2 (fr)
TW (1)	TWI245770B (fr)
WO (1)	WO2000004033A1 (fr)
YU (1)	YU3401A (fr)
ZA (1)	ZA200100417B (fr)

Families Citing this family (57)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB9914821D0 (en) *	1999-06-24	1999-08-25	Glaxo Group Ltd	Compounds
PL204924B1 (pl) *	1999-10-06	2010-02-26	Tibotec Pharm Ltd	Heksahydrofuro [2,3-b] furanylo-3-N-{3(1,3-benzodioksolilo-5-sulfonylo) (izobutylo) amino] -1-benzylo-2-hydroksypropylo} karbaminian oraz jego zastosowanie
HU230030B1 (hu)	1999-10-08	2015-05-28	Debiopharm International Sa	Fab I inhibitorok
EP1560584B1 (fr) *	2001-04-06	2009-01-14	Affinium Pharmaceuticals, Inc.	Inhibiteurs de fab i
WO2003091264A2 (fr) *	2002-04-26	2003-11-06	Gilead Sciences, Inc.	Inhibiteurs non nucleosidiques de la transcriptase inverse
EP1575951B1 (fr) *	2002-12-06	2014-06-25	Debiopharm International SA	Composes heterocycliques, procedes de production de ceux-ci et utilisation de ceux-ci dans un traitement
WO2004082586A2 (fr)	2003-03-17	2004-09-30	Affinium Pharmaceuticals, Inc.	Compositions comportant plusieurs agents antibiotiques, et leurs procedes de mise en oeuvre
US7452901B2 (en)	2003-04-25	2008-11-18	Gilead Sciences, Inc.	Anti-cancer phosphonate analogs
EA014685B1 (ru)	2003-04-25	2010-12-30	Джилид Сайэнс, Инк.	Фосфонатсодержащие антивирусные соединения (варианты) и фармацевтическая композиция на их основе
US7300924B2 (en)	2003-04-25	2007-11-27	Gilead Sciences, Inc.	Anti-infective phosphonate analogs
US7407965B2 (en)	2003-04-25	2008-08-05	Gilead Sciences, Inc.	Phosphonate analogs for treating metabolic diseases
WO2005002626A2 (fr)	2003-04-25	2005-01-13	Gilead Sciences, Inc.	Composes de phosphonate therapeutiques
KR20060022647A (ko)	2003-04-25	2006-03-10	길리애드 사이언시즈, 인코포레이티드	키나아제 억제 포스포네이트 유사체
US7470724B2 (en)	2003-04-25	2008-12-30	Gilead Sciences, Inc.	Phosphonate compounds having immuno-modulatory activity
US7427636B2 (en)	2003-04-25	2008-09-23	Gilead Sciences, Inc.	Inosine monophosphate dehydrogenase inhibitory phosphonate compounds
US7432261B2 (en)	2003-04-25	2008-10-07	Gilead Sciences, Inc.	Anti-inflammatory phosphonate compounds
US20080234288A1 (en) *	2003-09-30	2008-09-25	Kenneth Alan Simmen	Hcv Inhibiting Sulfonamides
WO2005044279A1 (fr)	2003-10-24	2005-05-19	Gilead Sciences, Inc.	Conjugues phosphonate / inhibiteur de purine nucleoside phosphorylase
WO2005044308A1 (fr)	2003-10-24	2005-05-19	Gilead Sciences, Inc.	Analogues phosphonates d'antimetabolites
WO2005042773A1 (fr)	2003-10-24	2005-05-12	Gilead Sciences, Inc.	Procedes et compositions permettant d'identifier des composes therapeutiques
BRPI0417988A (pt)	2003-12-22	2007-04-27	Gilead Sciences Inc	análogos de fosfonato antivirais
DK1828167T3 (da) *	2004-06-04	2014-10-20	Debiopharm Int Sa	Acrylamidderivater som antibiotiske midler
AU2005330489B2 (en)	2004-07-27	2011-08-25	Gilead Sciences, Inc.	Nucleoside phosphonate conjugates as anti HIV agents
SI2153870T1 (sl)	2004-11-26	2014-05-30	Ucl Business Plc	Sestavki, ki obsegajo ornitin in fenilacetat ali fenilbutirat, za zdravljenje hepatitične encefalopatije
KR20080075027A (ko) *	2005-12-05	2008-08-13	아피늄 파마슈티컬스, 인크.	Ｆａｂｉ 억제제 및 항박테리아제로서의헤테로시클릴아크릴아미드 화합물
JP5468899B2 (ja)	2006-07-20	2014-04-09	アフィニウムファーマシューティカルズ，インク．	Ｆａｂｉインヒビターとしてのアクリルアミド誘導体
EP2125802A4 (fr)	2007-02-16	2014-08-20	Debiopharm Int Sa	Sels, promédicaments et polymorphes d'inhibiteurs de fab 1
CN101631568B (zh)	2007-03-12	2012-08-22	尼克塔治疗公司	低聚物-蛋白酶抑制剂偶联物
US9095620B2 (en) *	2008-03-12	2015-08-04	Nektar Therapeutics	Reagents
US8658617B2 (en)	2008-07-08	2014-02-25	Gilead Sciences, Inc.	Salts of HIV inhibitor compounds
HUE035921T2 (en)	2009-04-03	2018-05-28	Ocera Therapeutics Inc	L-ornithine phenyl acetate and methods of making thereof
WO2010134045A1 (fr) *	2009-05-20	2010-11-25	Ranbaxy Laboratories Limited	Fosamprenavir calcique amorphe
CN104434894A (zh)	2009-06-08	2015-03-25	Ucl商业有限公司	使用l-鸟氨酸苯乙酸盐治疗门静脉高压和恢复肝功能
JP2012530069A (ja)	2009-06-12	2012-11-29	ネクターセラピューティックス	プロテアーゼ阻害剤、水溶性非ペプチドオリゴマーおよび親油性部分を含む共有結合体
US20120208787A1 (en) *	2009-06-30	2012-08-16	Ranbaxy Laboratories Limited	Crystalline form of fosamprenavir calcium
US9085592B2 (en)	2009-09-16	2015-07-21	Ranbaxy Laboratories Limited	Process for the preparation of fosamprenavir calcium
US20110165202A1 (en) *	2010-01-07	2011-07-07	Pliva Hrvatska D.O.O.	Solid state forms of fosamprenavir calcium salt and processes for preparation thereof
LT3494972T (lt)	2010-01-27	2024-03-12	Viiv Healthcare Company	Dolutegraviro ir lamivudino kompozicija živ infekcijai gydyti
US20110224443A1 (en) *	2010-03-15	2011-09-15	Venkata Naga Brahmeshwara Rao Mandava	Preparation of fosamprenavir calcium
WO2011114212A1 (fr)	2010-03-19	2011-09-22	Lupin Limited	Sels d'ammonium, de calcium et de tris de fosamprénavir
US20130211108A1 (en) *	2010-06-18	2013-08-15	Mylan Laboratories Ltd	Novel process for the preparation of (3s)-tetrahydrofuran-3-yl (is, 2r)-3-[[(4-aminophenyl) sulfonyl] (isobutyl) amino]-1-benzyl-2-(phosphonooxy) propylcarbamate and its pharmaceutically acceptable salts
EP2614055A2 (fr)	2010-09-10	2013-07-17	Lupin Limited	Procédé de préparation de calcium de fosamprenavir sensiblement pur et de ses intermédiaires
US8946473B2 (en)	2010-10-06	2015-02-03	Ocera Therapeutics, Inc.	Methods of making L-ornithine phenyl acetate
CN102453053B (zh) *	2010-10-29	2014-11-26	浙江九洲药业股份有限公司	一种福沙那韦钙晶体及其制备方法
CN102453054B (zh) *	2010-10-29	2015-06-10	浙江九洲药业股份有限公司	一种福沙那韦衍生物的制备方法及相关中间体
WO2012085625A1 (fr)	2010-12-21	2012-06-28	Lupin Limited	Procédé pour la préparation de fosamprénavir calcique et d'un intermédiaire utilisé dans sa préparation
US8993786B2 (en)	2011-02-10	2015-03-31	Mylan Laboratories Ltd.	Crystalline fosamprenavir calcium and process for the preparation thereof
WO2013011485A1 (fr)	2011-07-20	2013-01-24	Ranbaxy Laboratories Limited	Procédé de préparation de sulfonamides utiles en tant qu'inhibiteurs de protéase rétroviraux
IN2012DE00082A (fr)	2012-01-10	2015-05-01	Council Scient Ind Res
AU2013279021C1 (en)	2012-06-19	2017-03-16	Debiopharm International Sa	Prodrug derivatives of (E)-N-methyl-N-((3-methylbenzofuran-2-yl)methyl)-3-(7-oxo-5,6,7,8-tetrahydro-1,8-naphthyridin-3-yl)acrylamide
ES2769000T3 (es)	2014-11-24	2020-06-24	Ucl Business Ltd	Tratamiento de enfermedades asociadas con la activación de células estrelladas hepáticas utilizando terapias reductoras de amoníaco
WO2017031131A1 (fr)	2015-08-18	2017-02-23	Ocera Therapeutics, Inc.	Traitement et prévention de la perte musculaire au moyen de l-ornithine en combinaison avec au moins un parmi l'acétate de phényle et le butyrate de phényle
RS61312B1 (sr)	2016-02-26	2021-02-26	Debiopharm Int Sa	Lek za lečenje infekcija dijabetskog stopala
MX389665B (es)	2017-05-11	2025-03-20	Ocera Therapeutics Inc	Procesos para producir fenilacetato de l-ornitina
SI3661937T1 (sl)	2017-08-01	2021-11-30	Gilead Sciences, Inc.	Kristalinične oblike etil((S)-((((2R,5R)-5-(6-amino-9H-purin-9-IL)-4- fluoro-2,5-dihidrofuran-2-IL)oksi)metil)(fenoksi)fosforil)-L-alaninata (GS-9131) za zdravljenje virusnih okužb
TN2021000159A1 (en)	2019-02-14	2023-04-04	Debiopharm Int Sa	Afabicin formulation, method for making the same and uses thereof
SG11202113174SA (en)	2019-06-14	2021-12-30	Debiopharm Int Sa	Medicament and use thereof for treating bacterial infections involving biofilm

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US2698826A (en) *	1951-02-13	1955-01-04	Merco Centrifugal Co	Alcohol manufacturing process
US3437267A (en) *	1966-03-24	1969-04-08	Alfa Laval Ab	Centrifuge
JPH0244315B2 (ja) *	1982-06-14	1990-10-03	Microbial Chem Res Found	Supagarinn155hosufueetooyobisonoseizoho
US5723490A (en) *	1992-09-08	1998-03-03	Vertex Pharmaceuticals Incorporated	THF-containing sulfonamide inhibitors of aspartyl protease
UA49803C2 (uk) *	1994-06-03	2002-10-15	Дж.Д. Сьорль Енд Ко	Спосіб лікування ретровірусних інфекцій
WO1999033792A2 (fr) *	1997-12-24	1999-07-08	Vertex Pharmaceuticals Incorporated	Promedicaments des inhibiteurs de l'aspartyl-transferase
EA200000702A1 (ru) *	1997-12-24	2000-12-25	Вертекс Фармасьютикалз Инкорпорейтед	Пролекарства ингибиторов аспартилпротеаз
US6436989B1 (en) *	1997-12-24	2002-08-20	Vertex Pharmaceuticals, Incorporated	Prodrugs of aspartyl protease inhibitors
GB9812189D0 (en) *	1998-06-05	1998-08-05	Glaxo Group Ltd	Methods and compositions for increasing penetration of HIV protease inhibitors
AU6329599A (en) *	1998-09-28	2000-04-17	Glaxo Group Limited	Antiviral combinations comprising (s)-2-ethyl -7-fluoro -3-oxo-3, 4-dihydro -2h-quinoxaline -1-carboxylic acid isopropyl ester
AU762349B2 (en) *	1998-11-04	2003-06-26	Pharmacia & Upjohn Company	Method for improving the pharmacokinetics of tipranavir
CZ20002364A3 (cs) *	1998-12-23	2000-11-15	Vertex Pharmaceuticals Incorporated	Deriváty sulfonamidů a farmaceutický prostředek, který je obsahuje
GB9914821D0 (en) *	1999-06-24	1999-08-25	Glaxo Group Ltd	Compounds
US6642237B1 (en) *	1999-11-24	2003-11-04	Merck & Co., Inc.	Gamma-hydroxy-2-(fluoroalkylaminocarbonyl)-1-piperazinepentanamides and uses thereof

1998
- 1998-07-18 GB GBGB9815567.4A patent/GB9815567D0/en not_active Ceased
1999
- 1999-07-14 AR ARP990103446A patent/AR019388A1/es not_active Application Discontinuation
- 1999-07-14 GC GCP1999203 patent/GC0000105A/xx active
- 1999-07-14 DZ DZ990145A patent/DZ2845A1/fr active
- 1999-07-15 AP APAP/P/2001/002039A patent/AP2001002039A0/en unknown
- 1999-07-15 HU HU0103432A patent/HU229700B1/hu unknown
- 1999-07-15 EP EP02013136A patent/EP1240903A3/fr not_active Withdrawn
- 1999-07-15 AT AT99934698T patent/ATE229964T1/de active
- 1999-07-15 JP JP2000560139A patent/JP3437553B2/ja not_active Expired - Lifetime
- 1999-07-15 CA CA2337857A patent/CA2337857C/fr not_active Expired - Lifetime
- 1999-07-15 TR TR2001/00111T patent/TR200100111T2/xx unknown
- 1999-07-15 EA EA200100053A patent/EA003191B1/ru not_active IP Right Cessation
- 1999-07-15 CN CNB998108383A patent/CN1188422C/zh not_active Expired - Lifetime
- 1999-07-15 HR HR20010046A patent/HRP20010046A2/hr not_active Application Discontinuation
- 1999-07-15 PL PL99345620A patent/PL195736B1/pl unknown
- 1999-07-15 WO PCT/EP1999/004991 patent/WO2000004033A1/fr not_active Ceased
- 1999-07-15 GE GEAP19995716A patent/GEP20033030B/en unknown
- 1999-07-15 JO JO19992114A patent/JO2114B1/en active
- 1999-07-15 GT GT199900111A patent/GT199900111A/es unknown
- 1999-07-15 SK SK76-2001A patent/SK285311B6/sk not_active IP Right Cessation
- 1999-07-15 EE EEP200100038A patent/EE200100038A/xx unknown
- 1999-07-15 KR KR1020017000740A patent/KR100694721B1/ko not_active Expired - Lifetime
- 1999-07-15 DE DE69904600T patent/DE69904600T2/de not_active Expired - Lifetime
- 1999-07-15 AU AU50379/99A patent/AU766056B2/en not_active Expired
- 1999-07-15 PE PE1999000714A patent/PE20000869A1/es not_active Application Discontinuation
- 1999-07-15 OA OA1200100016A patent/OA11706A/fr unknown
- 1999-07-15 ES ES99934698T patent/ES2189450T3/es not_active Expired - Lifetime
- 1999-07-15 TN TNTNSN99145A patent/TNSN99145A1/fr unknown
- 1999-07-15 CZ CZ20010219A patent/CZ300447B6/cs not_active IP Right Cessation
- 1999-07-15 SV SV1999000096A patent/SV1999000096A/es not_active Application Discontinuation
- 1999-07-15 YU YU3401A patent/YU3401A/sh unknown
- 1999-07-15 EP EP99934698A patent/EP1098898B1/fr not_active Expired - Lifetime
- 1999-07-15 IL IL14082499A patent/IL140824A/en not_active IP Right Cessation
- 1999-07-15 ID IDW20010145A patent/ID28070A/id unknown
- 1999-07-15 DK DK99934698T patent/DK1098898T3/da active
- 1999-07-15 CO CO99044882A patent/CO5090836A1/es unknown
- 1999-07-15 BR BRPI9912156A patent/BRPI9912156B8/pt not_active IP Right Cessation
- 1999-07-15 NZ NZ509291A patent/NZ509291A/en not_active IP Right Cessation
- 1999-07-15 MA MA25684A patent/MA26660A1/fr unknown
- 1999-07-15 US US09/744,051 patent/US6514953B1/en not_active Expired - Lifetime
- 1999-07-15 PT PT99934698T patent/PT1098898E/pt unknown
- 1999-07-15 MY MYPI99002983A patent/MY122323A/en unknown
- 1999-07-16 PA PA19998477801A patent/PA8477801A1/es unknown
- 1999-08-06 TW TW088113428A patent/TWI245770B/zh not_active IP Right Cessation
2001
- 2001-01-12 IS IS5808A patent/IS5808A/is unknown
- 2001-01-15 ZA ZA200100417A patent/ZA200100417B/en unknown
- 2001-01-17 NO NO20010282A patent/NO329676B1/no not_active IP Right Cessation
- 2001-02-14 BG BG105253A patent/BG105253A/xx unknown
2002
- 2002-11-25 US US10/303,213 patent/US20030100537A1/en not_active Abandoned
- 2002-11-25 US US10/303,366 patent/US20030096795A1/en not_active Abandoned

Also Published As

Publication number	Publication date
WO2000004033A1 (fr)	2000-01-27
AR019388A1 (es)	2002-02-13
NO20010282L (no)	2001-03-07
US6514953B1 (en)	2003-02-04
ES2189450T3 (es)	2003-07-01
GB9815567D0 (en)	1998-09-16
CN1188422C (zh)	2005-02-09
PL195736B1 (pl)	2007-10-31
DK1098898T3 (da)	2003-04-07
TNSN99145A1 (fr)	2005-11-10
IS5808A (is)	2001-01-12
DE69904600T2 (de)	2003-11-13
NO329676B1 (no)	2010-11-29
NO20010282D0 (no)	2001-01-17
NZ509291A (en)	2003-05-30
BRPI9912156B8 (pt)	2021-05-25
MY122323A (en)	2006-04-29
OA11706A (en)	2005-01-13
SV1999000096A (es)	2000-07-06
KR100694721B1 (ko)	2007-03-15
SK285311B6 (sk)	2006-10-05
IL140824A (en)	2004-09-27
EP1240903A3 (fr)	2003-02-12
CN1324363A (zh)	2001-11-28
EA003191B1 (ru)	2003-02-27
PT1098898E (pt)	2003-04-30
GC0000105A (en)	2005-06-29
HUP0103432A2 (hu)	2002-04-29
AU5037999A (en)	2000-02-07
CO5090836A1 (es)	2001-10-30
CZ300447B6 (cs)	2009-05-20
PL345620A1 (en)	2002-01-02
KR20010071952A (ko)	2001-07-31
US20030100537A1 (en)	2003-05-29
MA26660A1 (fr)	2004-12-20
HU229700B1 (en)	2014-05-28
AP2001002039A0 (en)	2001-03-31
AU766056B2 (en)	2003-10-09
CA2337857A1 (fr)	2000-01-27
DE69904600D1 (de)	2003-01-30
IL140824A0 (en)	2002-02-10
HUP0103432A3 (en)	2003-01-28
BRPI9912156B1 (pt)	2016-07-26
BG105253A (en)	2001-12-29
JO2114B1 (en)	2000-05-21
GT199900111A (es)	2001-01-05
TR200100111T2 (tr)	2002-02-21
GEP20033030B (en)	2003-07-25
JP3437553B2 (ja)	2003-08-18
ZA200100417B (en)	2002-02-27
US20030096795A1 (en)	2003-05-22
SK762001A3 (en)	2001-10-08
ATE229964T1 (de)	2003-01-15
ID28070A (id)	2001-05-03
JP2003521447A (ja)	2003-07-15
EP1098898A1 (fr)	2001-05-16
PE20000869A1 (es)	2000-09-08
YU3401A (sh)	2005-06-10
EE200100038A (et)	2002-06-17
CA2337857C (fr)	2011-01-25
EP1098898B1 (fr)	2002-12-18
HK1034261A1 (en)	2001-10-19
BR9912156A (pt)	2001-04-10
EA200100053A1 (ru)	2001-08-27
EP1240903A2 (fr)	2002-09-18
CZ2001219A3 (cs)	2001-07-11
HRP20010046A2 (en)	2002-02-28
PA8477801A1 (es)	2000-05-24
TWI245770B (en)	2005-12-21

Publication	Publication Date	Title
DZ2845A1 (fr)	2003-12-01	Calcium (3S) tétrahydro-3-furanyle(1S,2R)-3-ÄÄ(4-aminophényle)sulfonyleÜ(sobutyle)aminoÜ-1-benzyle-2(phosphonooxy)propylcarbamate.
DZ2740A1 (fr)	2003-09-08	Catalyseurs de polymésation.
DZ2737A1 (fr)	2003-09-01	Catalyseurs de polymérisation.
DZ2738A1 (fr)	2003-12-01	Catalyseurs de polymérisation.
BR9700369B1 (pt)	2009-01-13	compostos de dimetil-(3-aril-but-3- enil)-amina.
IT1303332B1 (it)	2000-11-06	Plantare pronosupinante per calzature.
NO963526D0 (no)	1996-08-23	N-metyl-N-[(1S)-1-fenyl-2-((3S)-3-hydroksypyrrolidin-1-yl)-etylÅ-2,2-difenylacetamid
FR2763498B1 (fr)	1999-08-20	Endoscope, en particulier mediastinoscope
ITTO950478A0 (it)	1995-06-09	Rotore per elicotteri.
AU5818100A (en)	2001-01-31	Derivatives of (3s) tetrahydro-3-furanyl (1s,2r)-3-[[(4-aminophenyl)sulfonyl](isobutyl)amino]-1-benzy -2-(phosphonooxy)propylcarbamate
IT1304039B1 (it)	2001-03-02	Gommatore.
NL1010255A1 (nl)	1999-04-08	Bollenplanter.
ES1033492Y (es)	1997-02-01	Mojon de limitacion vial, amovible.
SI1098898T1 (en)	2003-08-31	Calcium (3s) tetrahydro-3-furanyl(1s,2r)-3-(((4-aminophenyl) sulfonyl) (isobutyl) amino) -1-benzyl-2- (phosphonooxy) propylcarbamate
ES1037296Y (es)	1998-06-16	Juego de construccion, dinamico.
ES1041422Y (es)	2000-01-01	Dispositivo emparejador de unidades de calzado.
ES1030098Y (es)	1996-01-01	Tapa-casquillo nivelador, para somieres de ballestas.
ES1031565Y (es)	1996-06-16	Suela de calzado, perfeccionada.
ES1037688Y (es)	1998-11-01	Dispositivo de ayuda para la expectoracion, no invasivo.
ES1040568Y (es)	1999-08-16	Instrumento de escritura.
IT239134Y1 (it)	2001-02-19	Dispositivo aspirante, particolarmente per w.c.
IT245540Y1 (it)	2002-03-22	Struttura di supporto, particolarmente per calzature.
ES1039379Y (es)	1999-05-01	Bigudi retenedor de humedad.
ES1036214Y (es)	1997-12-01	Sillita-carrito de paseo-mochila, para muñecos.
ITBO980069A0 (it)	1998-02-11	Piattaforma rotante per autoveicoli.