ATE241365T1 - Saccharid-enthaltende zubereitungen zur behandlung von alzheimerschen erkrankung und von weiteren amyloidosen - Google Patents
Saccharid-enthaltende zubereitungen zur behandlung von alzheimerschen erkrankung und von weiteren amyloidosenInfo
- Publication number
- ATE241365T1 ATE241365T1 AT98943468T AT98943468T ATE241365T1 AT E241365 T1 ATE241365 T1 AT E241365T1 AT 98943468 T AT98943468 T AT 98943468T AT 98943468 T AT98943468 T AT 98943468T AT E241365 T1 ATE241365 T1 AT E241365T1
- Authority
- AT
- Austria
- Prior art keywords
- disease
- alzheimer
- amyloidoses
- treatment
- preparations containing
- Prior art date
Links
- 206010002022 amyloidosis Diseases 0.000 title abstract 3
- 150000001720 carbohydrates Chemical class 0.000 title abstract 3
- 208000024827 Alzheimer disease Diseases 0.000 title abstract 2
- 206010002023 Amyloidoses Diseases 0.000 title 1
- 238000002360 preparation method Methods 0.000 title 1
- 239000008177 pharmaceutical agent Substances 0.000 abstract 3
- 125000000129 anionic group Chemical group 0.000 abstract 2
- NNVRATBUZLFTQG-SLPGGIOYSA-N [(2r,3s,4r,5r)-1-oxo-2,4,5,6-tetrasulfooxyhexan-3-yl] hydrogen sulfate Chemical compound OS(=O)(=O)OC[C@@H](OS(O)(=O)=O)[C@@H](OS(O)(=O)=O)[C@H](OS(O)(=O)=O)[C@@H](OS(O)(=O)=O)C=O NNVRATBUZLFTQG-SLPGGIOYSA-N 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 239000003085 diluting agent Substances 0.000 abstract 1
- 239000003937 drug carrier Substances 0.000 abstract 1
- 239000000546 pharmaceutical excipient Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7024—Esters of saccharides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Neurosurgery (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Molecular Biology (AREA)
- Epidemiology (AREA)
- Biomedical Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Neurology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US5714497P | 1997-08-28 | 1997-08-28 | |
| PCT/US1998/017952 WO1999009999A1 (en) | 1997-08-28 | 1998-08-28 | Specific saccharide compositions and methods for treating alzheimer's disease and other amyloidoses |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE241365T1 true ATE241365T1 (de) | 2003-06-15 |
Family
ID=22008776
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT98943468T ATE241365T1 (de) | 1997-08-28 | 1998-08-28 | Saccharid-enthaltende zubereitungen zur behandlung von alzheimerschen erkrankung und von weiteren amyloidosen |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US6037327A (de) |
| EP (1) | EP1014996B1 (de) |
| JP (1) | JP4659209B2 (de) |
| AT (1) | ATE241365T1 (de) |
| AU (1) | AU9125798A (de) |
| CA (1) | CA2301725C (de) |
| DE (1) | DE69815122T2 (de) |
| DK (1) | DK1014996T3 (de) |
| ES (1) | ES2200366T3 (de) |
| WO (1) | WO1999009999A1 (de) |
Families Citing this family (62)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20030017998A1 (en) * | 1997-05-16 | 2003-01-23 | Snow Alan D. | Proanthocyanidins for the treatment of amyloid and alpha-synuclein diseases |
| EP0899957A1 (de) * | 1997-08-27 | 1999-03-03 | Koninklijke Philips Electronics N.V. | Vorrichtung zur drahtlosen Verbreitung von Fernsehsignalen in einer Wohnung |
| ATE279502T1 (de) * | 1997-09-09 | 2004-10-15 | Ciba Sc Holding Ag | Verfahren zur gewebepflege |
| US6114405A (en) * | 1997-10-09 | 2000-09-05 | Research Frontiers Incorporated | Ultraviolet radiation-curable light-modulating film for a light valve, and method of making same |
| BE1011535A3 (nl) * | 1997-11-05 | 1999-10-05 | Framatome Connectors Belgium | Werkwijze en inrichting voor het opmeten van de positie van een reeks contactpennen en voor het aanbrengen van deze reeks in een plaat met gedrukte schakelingen. |
| GB2332314B (en) * | 1997-12-09 | 2001-05-16 | Sony Uk Ltd | Interface for a receiver and method of arrangement thereof |
| KR100552914B1 (ko) * | 1998-07-10 | 2006-06-28 | 제일모직주식회사 | 칼러레지스트수지조성물 |
| KR20000014564A (ko) * | 1998-08-21 | 2000-03-15 | 윤종용 | 통합 메시징 시스템의 수신 팩스 데이터 편집 및 재전송방법 |
| US6767898B2 (en) * | 1998-08-28 | 2004-07-27 | University Of Washington | Methods for using specific saccharides for treating alzheimer's disease and other amyloidoses |
| KR100389295B1 (ko) * | 1998-09-28 | 2003-12-18 | 에스케이씨 주식회사 | 폴리에스테르필름및그제조방법 |
| KR100548233B1 (ko) * | 1998-12-15 | 2006-05-09 | 엘지전자 주식회사 | 네트워크를 이용한 양방향 방송 시스템 |
| KR100593996B1 (ko) * | 1998-12-17 | 2006-09-27 | 삼성전자주식회사 | 휴대폰에서의 배경화면 디스플레이방법 |
| US6562836B1 (en) * | 1999-05-24 | 2003-05-13 | Queen's University Of Kingston | Methods and compounds for inhibiting amyloid deposits |
| US6159986A (en) * | 1999-11-02 | 2000-12-12 | Altman; David A. | Compounds and therapy for resisting memory loss in humans |
| US6689753B1 (en) * | 1999-11-05 | 2004-02-10 | Axonyx, Inc. | β sheet breaker peptide analogs that inhibit β pleated sheet formation in amyloid β-peptide |
| EP1251837A2 (de) * | 1999-12-23 | 2002-10-30 | Neurochem, Inc. | Verbindungen und verfahren zur modulierung von amyloider gehirnangiopathie |
| US20010047032A1 (en) * | 1999-12-30 | 2001-11-29 | Castillo Gerardo M. | Polyhydroxylated aromatic compounds for the treatment of amyloidosis and alpha-synuclein fibril diseases |
| KR100440370B1 (ko) * | 2000-04-01 | 2004-07-19 | (주)명문엘씨 | 2중 사출에 의한 밀폐용기 뚜껑 |
| US6641801B1 (en) * | 2000-04-03 | 2003-11-04 | Love Lives | Gargle method to reduce the duration of common cold symptoms |
| KR100359892B1 (ko) * | 2000-04-21 | 2002-11-07 | 김미자 | 온라인 안경 조제 시스템 및 그 방법 |
| JP4660026B2 (ja) * | 2000-09-08 | 2011-03-30 | パナソニック株式会社 | 表示パネルの駆動装置 |
| US20070208087A1 (en) | 2001-11-02 | 2007-09-06 | Sanders Virginia J | Compounds, compositions and methods for the treatment of inflammatory diseases |
| KR20020035987A (ko) * | 2000-11-07 | 2002-05-16 | 백윤강 | 잣열매자동채취시스템 |
| KR100427942B1 (ko) * | 2001-09-05 | 2004-04-30 | 현대자동차주식회사 | 핀 연결 구조를 가진 인젝터 인슐레이션 플러그 |
| KR100486365B1 (ko) * | 2001-09-13 | 2005-04-29 | 주식회사 태평양 | 여성 갱년기 증후군 개선 효과를 갖는 조성물 |
| KR100420594B1 (ko) * | 2001-09-20 | 2004-03-02 | 병 목 이 | 태양 에너지의 복합 이용장치 |
| KR20030026095A (ko) * | 2001-09-24 | 2003-03-31 | 김덕교 | 요실금 수술을 위한 국소마취삽입기, 테이프, 테이프견인기구와 이들을 포함하는 외과수술장치 |
| KR100444446B1 (ko) * | 2001-09-29 | 2004-08-16 | 현대자동차주식회사 | 인젝션 노즐 |
| KR20020000538A (ko) * | 2001-12-05 | 2002-01-05 | 이정욱 | 이더넷을 이용한 무선로봇의 원격제어 시스템 |
| KR100428181B1 (ko) * | 2001-12-17 | 2004-04-28 | 현대자동차주식회사 | 디젤 엔진의 배기 재 순환 제어 장치 및 그 방법 |
| KR20030050150A (ko) * | 2001-12-18 | 2003-06-25 | 현대자동차주식회사 | 도로 상황 판정 시스템 및 그 방법 |
| KR100427868B1 (ko) * | 2001-12-18 | 2004-04-28 | 주식회사 백금정보통신 | 광대역 레이더 검출기 회로 |
| WO2003059387A2 (en) * | 2001-12-21 | 2003-07-24 | Ilex Oncology, Inc. | Combination comprising anti-cd52 antibodies and other therapeutic agents for treatment for multiple sclerosis |
| KR20030055648A (ko) * | 2001-12-27 | 2003-07-04 | 이인영 | 금속판 절단용 커터 |
| EP1820806A1 (de) * | 2006-02-16 | 2007-08-22 | Crossbeta Biosciences B.V. | Affinitätsbereiche |
| WO2003101927A1 (en) * | 2002-05-31 | 2003-12-11 | Proteotech, Inc. | Compounds, compositions and methods for the treatment of amyloid diseases and synucleinopathies such as alzheimer's disease, type 2 diabetes, and parkinson's disease |
| US20070003552A1 (en) * | 2002-07-09 | 2007-01-04 | Gebbink Martijn F B | Cross-beta structure comprising amyloid binding proteins and methods for detection of the cross-beta structure, for modulating cross-beta structures fibril formation and for modulating cross-beta structure-mediated toxicity and method for interfering with blood coagulation |
| EP1380290A1 (de) * | 2002-07-09 | 2004-01-14 | Universitair Medisch Centrum Utrecht | Cross-Beta-Strukturweg und seine therapeutische Relevanz |
| KR100438731B1 (ko) * | 2002-07-27 | 2004-07-05 | 삼성전자주식회사 | 잉크 젯 노즐 상태에 따른 원고 인쇄 방법 및 장치 |
| KR100452372B1 (ko) * | 2002-07-29 | 2004-10-12 | 엘지전자 주식회사 | 건조기의 도어 |
| KR100464732B1 (ko) * | 2002-09-02 | 2005-01-05 | 에스케이텔레텍주식회사 | 회전형 안테나를 구비하는 폴더형 이동통신단말기 |
| EP1554270A2 (de) * | 2002-10-11 | 2005-07-20 | Proteotech, Inc. | Isolierung, reinigung und synthese von procyanidin b2 sowie seine verwendung |
| US20070010573A1 (en) * | 2003-06-23 | 2007-01-11 | Xianqi Kong | Methods and compositions for treating amyloid-related diseases |
| US7414076B2 (en) * | 2003-06-23 | 2008-08-19 | Neurochem (International) Limited | Methods and compositions for treating amyloid-related diseases |
| US7244764B2 (en) * | 2003-06-23 | 2007-07-17 | Neurochem (International) Limited | Methods and compositions for treating amyloid-related diseases |
| WO2005077382A1 (ja) * | 2004-02-17 | 2005-08-25 | National Institute Of Advanced Industrial Science And Technology | プリオン増殖抑制剤 |
| EP1828111A2 (de) * | 2004-11-12 | 2007-09-05 | Neurochem (International) Limited | Verfahren und fluorierte zusammensetzungen zur behandlung von amyloidbedingten krankheiten |
| CN101103018A (zh) * | 2004-11-16 | 2008-01-09 | 神经化学(国际)有限公司 | 治疗cns和淀粉样蛋白-相关疾病的化合物 |
| BRPI0519243A2 (pt) * | 2004-12-22 | 2009-01-06 | Neurochem Int Ltd | mÉtodos e composiÇÕes para tratar doenÇas relacionadas a amilàide |
| JP5082099B2 (ja) * | 2005-02-03 | 2012-11-28 | 国立大学法人名古屋大学 | アミロイドβ蛋白凝集制御剤 |
| AU2006267176A1 (en) * | 2005-07-13 | 2007-01-18 | Crossbeta Biosciences B.V. | Cross-beta structure binding compounds |
| US20070015133A1 (en) * | 2005-07-13 | 2007-01-18 | Umc Utrecht Holding B.V. | Method for detecting and/or removing protein and/or peptide comprising a cross-beta structure from an aqueous solution comprising a protein |
| US8114832B2 (en) * | 2005-07-13 | 2012-02-14 | Crossbeta Biosciences B.V. | Method for detecting and/or removing a protein comprising a cross-beta structure from a pharmaceutical composition |
| BRPI0613525A2 (pt) * | 2005-07-13 | 2011-05-31 | Crossbeta Biosciences Bv | métodos para produzir uma composição imunogênica, para melhorar a imunogenicidade de uma composição, para intensificar a imunogenicidade de uma composição de vacina, e para determinar a quantidade de estruturas beta-cruzadas em uma composição de vacina, usos de estruturas beta-cruzadas, e de uma composição imunogênica, vacina de subunidade, e, composição imunogênica |
| JP4981036B2 (ja) * | 2006-04-20 | 2012-07-18 | 伊藤ハム株式会社 | コンフォメーション病医薬組成物 |
| WO2007137808A1 (en) * | 2006-05-29 | 2007-12-06 | University College Dublin, National University Of Ireland, Dublin | Compositions comprising oligosaccharides for treating prion disease |
| DK2089417T3 (en) | 2006-10-12 | 2015-03-23 | Bhi Ltd Partnership | Methods, Compounds, Compositions and Vehicles for Delivery of 3-Amion-1-Propanesulfonic Acid |
| EP2058001A1 (de) * | 2007-11-08 | 2009-05-13 | Crossbeta Biosciences B.V. | Steigerung der Immunogenizität von Antigenen |
| EP2058000A1 (de) * | 2007-11-08 | 2009-05-13 | Crossbeta Biosciences B.V. | Zur Aktivierung von T-Zellen fähige immunogene Zusammensetzung |
| JP2015526409A (ja) * | 2012-07-03 | 2015-09-10 | ヤンセン・サイエンシズ・アイルランド・ユーシー | C−末端及び中心エピトープa−ベータ抗体 |
| WO2015184231A2 (en) * | 2014-05-30 | 2015-12-03 | Kolltan Pharmaceuticals, Inc. | Regulators of anaplastic lymphoma kinase and uses thereof |
| EP3628315A1 (de) | 2018-09-28 | 2020-04-01 | Université de Caen Normandie | Kombination aus acetylcholinesterase-inhibitor und 5-ht4-rezeptoragonist als neuroprotektives mittel zur behandlung von neurodegenerativen krankheiten |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1110939A (en) * | 1965-10-06 | 1968-04-24 | Meito Sangyo Kk | Sulphuric acid esters of disaccharides and hexitols,and their use as antipeptic ulcer agents |
| GB1381426A (en) * | 1973-04-10 | 1975-01-22 | Chugai Pharmaceutical Co Ltd | Method of treating mammals and composition comprising oligosaccha ride sulphuric acid esters and nonionic surface active agents |
| US4098995A (en) * | 1976-07-12 | 1978-07-04 | American Cyanamid Company | Polygalactosido-sucrose poly(h-)sulfate salts |
| US4912093A (en) * | 1986-10-01 | 1990-03-27 | Marion Laboratories, Inc. | Use of synthetic sulfated saccharides to enhance wound healing |
| ZA869530B (en) * | 1985-12-24 | 1987-10-28 | Marion Laboratories Inc | Use of synthetic sulfated saccharides to enhance wound healing |
| IT1205042B (it) * | 1987-05-28 | 1989-03-10 | Crinos Industria Farmaco | Composizione farmaceutica ad attivita' terapeutica per il trattamento della demenza senile di tipo alzheimer |
| JPH0347128A (ja) * | 1989-07-13 | 1991-02-28 | Chugai Pharmaceut Co Ltd | 鼻粘膜保護剤 |
| US5242932A (en) * | 1991-12-17 | 1993-09-07 | The Rockefeller University | Treatment of amyloidosis associated with alzheimer disease |
| US5643562A (en) * | 1993-03-29 | 1997-07-01 | Queen's University Of Kingston | Method for treating amyloidosis |
| US5840294A (en) * | 1993-03-29 | 1998-11-24 | Queen's University At Kingston | Method for treating amyloidosis |
| US5388574A (en) * | 1993-07-29 | 1995-02-14 | Ingebrethsen; Bradley J. | Aerosol delivery article |
| AUPN261895A0 (en) * | 1995-04-28 | 1995-05-18 | Australian National University, The | Preparation and use of sulfated oligosaccharides |
| US5723589A (en) * | 1995-12-21 | 1998-03-03 | Icn Pharmaceuticals | Carbohydrate conjugated bio-active compounds |
| WO1999045947A1 (en) * | 1998-03-13 | 1999-09-16 | University Of Washington | In vitro formation of congophilic maltese-cross amyloid plaques to identify anti-plaque therapeutics for the treatment of alzheimer's and prion diseases |
-
1998
- 1998-08-28 AU AU91257/98A patent/AU9125798A/en not_active Abandoned
- 1998-08-28 AT AT98943468T patent/ATE241365T1/de not_active IP Right Cessation
- 1998-08-28 US US09/141,628 patent/US6037327A/en not_active Expired - Lifetime
- 1998-08-28 ES ES98943468T patent/ES2200366T3/es not_active Expired - Lifetime
- 1998-08-28 CA CA002301725A patent/CA2301725C/en not_active Expired - Fee Related
- 1998-08-28 DE DE69815122T patent/DE69815122T2/de not_active Expired - Lifetime
- 1998-08-28 DK DK98943468T patent/DK1014996T3/da active
- 1998-08-28 EP EP98943468A patent/EP1014996B1/de not_active Expired - Lifetime
- 1998-08-28 JP JP2000507389A patent/JP4659209B2/ja not_active Expired - Fee Related
- 1998-08-28 WO PCT/US1998/017952 patent/WO1999009999A1/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| EP1014996A1 (de) | 2000-07-05 |
| JP4659209B2 (ja) | 2011-03-30 |
| US6037327A (en) | 2000-03-14 |
| JP2001513569A (ja) | 2001-09-04 |
| CA2301725C (en) | 2008-11-18 |
| EP1014996A4 (de) | 2000-10-11 |
| DE69815122D1 (de) | 2003-07-03 |
| AU9125798A (en) | 1999-03-16 |
| CA2301725A1 (en) | 1999-03-04 |
| ES2200366T3 (es) | 2004-03-01 |
| EP1014996B1 (de) | 2003-05-28 |
| DE69815122T2 (de) | 2003-12-24 |
| DK1014996T3 (da) | 2003-09-29 |
| WO1999009999A1 (en) | 1999-03-04 |
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