ATE258946T1 - Verfahren zur herstellung von polyamidketten von genauer länge und deren konjugate mit proteinen - Google Patents
Verfahren zur herstellung von polyamidketten von genauer länge und deren konjugate mit proteinenInfo
- Publication number
- ATE258946T1 ATE258946T1 AT99943873T AT99943873T ATE258946T1 AT E258946 T1 ATE258946 T1 AT E258946T1 AT 99943873 T AT99943873 T AT 99943873T AT 99943873 T AT99943873 T AT 99943873T AT E258946 T1 ATE258946 T1 AT E258946T1
- Authority
- AT
- Austria
- Prior art keywords
- chains
- conjugates
- proteins
- precise length
- producing polyamide
- Prior art date
Links
- 239000004952 Polyamide Substances 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- 229920002647 polyamide Polymers 0.000 title 1
- 102000004169 proteins and genes Human genes 0.000 title 1
- 108090000623 proteins and genes Proteins 0.000 title 1
- 239000002202 Polyethylene glycol Substances 0.000 abstract 1
- 150000004985 diamines Chemical class 0.000 abstract 1
- 229920002521 macromolecule Polymers 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 229920001223 polyethylene glycol Polymers 0.000 abstract 1
- 229920001184 polypeptide Polymers 0.000 abstract 1
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
- 239000000376 reactant Substances 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G73/00—Macromolecular compounds obtained by reactions forming a linkage containing nitrogen with or without oxygen or carbon in the main chain of the macromolecule, not provided for in groups C08G12/00 - C08G71/00
- C08G73/06—Polycondensates having nitrogen-containing heterocyclic rings in the main chain of the macromolecule
- C08G73/10—Polyimides; Polyester-imides; Polyamide-imides; Polyamide acids or similar polyimide precursors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
- C07K1/1072—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups
- C07K1/1077—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups by covalent attachment of residues other than amino acids or peptide residues, e.g. sugars, polyols, fatty acids
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G69/00—Macromolecular compounds obtained by reactions forming a carboxylic amide link in the main chain of the macromolecule
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G69/00—Macromolecular compounds obtained by reactions forming a carboxylic amide link in the main chain of the macromolecule
- C08G69/02—Polyamides derived from amino-carboxylic acids or from polyamines and polycarboxylic acids
- C08G69/04—Preparatory processes
- C08G69/06—Solid state polycondensation
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G69/00—Macromolecular compounds obtained by reactions forming a carboxylic amide link in the main chain of the macromolecule
- C08G69/02—Polyamides derived from amino-carboxylic acids or from polyamines and polycarboxylic acids
- C08G69/08—Polyamides derived from amino-carboxylic acids or from polyamines and polycarboxylic acids derived from amino-carboxylic acids
- C08G69/10—Alpha-amino-carboxylic acids
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Polymers & Plastics (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- General Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Analytical Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Polyamides (AREA)
- Peptides Or Proteins (AREA)
- Medicinal Preparation (AREA)
- Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Other Resins Obtained By Reactions Not Involving Carbon-To-Carbon Unsaturated Bonds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US9835198P | 1998-08-28 | 1998-08-28 | |
| US10526198P | 1998-10-22 | 1998-10-22 | |
| US12426699P | 1999-03-11 | 1999-03-11 | |
| PCT/US1999/019280 WO2000012587A2 (en) | 1998-08-28 | 1999-08-23 | Polyamide chains of precise length, methods to manufacture them and their conjugates |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE258946T1 true ATE258946T1 (de) | 2004-02-15 |
Family
ID=27378582
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT03023018T ATE364654T1 (de) | 1998-08-28 | 1999-08-23 | Polyamideketten von genauer länge und deren konjugate mit proteinen |
| AT99943873T ATE258946T1 (de) | 1998-08-28 | 1999-08-23 | Verfahren zur herstellung von polyamidketten von genauer länge und deren konjugate mit proteinen |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT03023018T ATE364654T1 (de) | 1998-08-28 | 1999-08-23 | Polyamideketten von genauer länge und deren konjugate mit proteinen |
Country Status (13)
| Country | Link |
|---|---|
| US (2) | US6552167B1 (de) |
| EP (1) | EP1107998B1 (de) |
| JP (1) | JP2002528562A (de) |
| KR (1) | KR20010085742A (de) |
| CN (1) | CN1330675A (de) |
| AT (2) | ATE364654T1 (de) |
| AU (1) | AU764144B2 (de) |
| CA (1) | CA2351739A1 (de) |
| DE (3) | DE69936322T2 (de) |
| DK (1) | DK1400551T3 (de) |
| ES (1) | ES2170042T3 (de) |
| HK (1) | HK1043801A1 (de) |
| WO (1) | WO2000012587A2 (de) |
Families Citing this family (94)
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|---|---|---|---|---|
| EP1107998B1 (de) * | 1998-08-28 | 2004-02-04 | Gryphon Sciences | Verfahren zur herstellung von polyamidketten von genauer länge und deren konjugate mit proteinen |
| DE19924606A1 (de) * | 1999-05-28 | 2000-11-30 | Graffinity Pharm Design Gmbh | Ligand-Anker-Konjugate |
| US8183339B1 (en) | 1999-10-12 | 2012-05-22 | Xigen S.A. | Cell-permeable peptide inhibitors of the JNK signal transduction pathway |
| US20040082509A1 (en) | 1999-10-12 | 2004-04-29 | Christophe Bonny | Cell-permeable peptide inhibitors of the JNK signal transduction pathway |
| KR20030046389A (ko) * | 2000-09-01 | 2003-06-12 | 그리폰 테라퓨틱스, 인코포레이티드 | 친핵체에 안정한 티오에스테르 발생 화합물, 제조 및 사용방법 |
| US7118737B2 (en) * | 2000-09-08 | 2006-10-10 | Amylin Pharmaceuticals, Inc. | Polymer-modified synthetic proteins |
| KR20030057529A (ko) * | 2000-09-08 | 2003-07-04 | 그리폰 테라퓨틱스, 인코포레이티드 | 합성 적혈구생성 자극 단백질 |
| US7034109B2 (en) | 2000-10-13 | 2006-04-25 | Christophe Bonny | Intracellular delivery of biological effectors |
| US7033597B2 (en) * | 2000-10-13 | 2006-04-25 | Université de Lausanne | Intracellular delivery of biological effectors |
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-
1999
- 1999-08-23 EP EP99943873A patent/EP1107998B1/de not_active Expired - Lifetime
- 1999-08-23 KR KR1020017002641A patent/KR20010085742A/ko not_active Withdrawn
- 1999-08-23 DE DE69936322T patent/DE69936322T2/de not_active Expired - Fee Related
- 1999-08-23 AT AT03023018T patent/ATE364654T1/de not_active IP Right Cessation
- 1999-08-23 ES ES99943873T patent/ES2170042T3/es not_active Expired - Lifetime
- 1999-08-23 JP JP2000567596A patent/JP2002528562A/ja active Pending
- 1999-08-23 HK HK02104731.4A patent/HK1043801A1/zh unknown
- 1999-08-23 CN CN99812465A patent/CN1330675A/zh active Pending
- 1999-08-23 WO PCT/US1999/019280 patent/WO2000012587A2/en not_active Ceased
- 1999-08-23 CA CA002351739A patent/CA2351739A1/en not_active Abandoned
- 1999-08-23 AU AU56883/99A patent/AU764144B2/en not_active Ceased
- 1999-08-23 US US09/379,297 patent/US6552167B1/en not_active Expired - Fee Related
- 1999-08-23 AT AT99943873T patent/ATE258946T1/de not_active IP Right Cessation
- 1999-08-23 DK DK03023018T patent/DK1400551T3/da active
- 1999-08-23 DE DE69914611T patent/DE69914611T2/de not_active Expired - Fee Related
- 1999-08-24 DE DE1107998T patent/DE1107998T1/de active Pending
-
2003
- 2003-03-06 US US10/379,585 patent/US20030228274A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| WO2000012587A3 (en) | 2000-06-02 |
| EP1107998A2 (de) | 2001-06-20 |
| KR20010085742A (ko) | 2001-09-07 |
| ATE364654T1 (de) | 2007-07-15 |
| WO2000012587A8 (en) | 2001-09-20 |
| ES2170042T1 (es) | 2002-08-01 |
| JP2002528562A (ja) | 2002-09-03 |
| WO2000012587A2 (en) | 2000-03-09 |
| CN1330675A (zh) | 2002-01-09 |
| DE69936322T2 (de) | 2008-02-21 |
| AU5688399A (en) | 2000-03-21 |
| AU764144B2 (en) | 2003-08-14 |
| DE1107998T1 (de) | 2002-10-17 |
| CA2351739A1 (en) | 2000-03-09 |
| EP1107998B1 (de) | 2004-02-04 |
| DE69914611T2 (de) | 2004-12-23 |
| DK1400551T3 (da) | 2007-10-15 |
| US20030228274A1 (en) | 2003-12-11 |
| DE69914611D1 (de) | 2004-03-11 |
| US6552167B1 (en) | 2003-04-22 |
| HK1043801A1 (zh) | 2002-09-27 |
| DE69936322D1 (de) | 2007-07-26 |
| ES2170042T3 (es) | 2004-10-01 |
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| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |