ATE261441T1 - Analoga von distamycin-zimtsäurederivaten, verfahren zu ihrer herstellung und ihre verwendung als antitumormittel - Google Patents

Analoga von distamycin-zimtsäurederivaten, verfahren zu ihrer herstellung und ihre verwendung als antitumormittel

Info

Publication number
ATE261441T1
ATE261441T1 AT99926405T AT99926405T ATE261441T1 AT E261441 T1 ATE261441 T1 AT E261441T1 AT 99926405 T AT99926405 T AT 99926405T AT 99926405 T AT99926405 T AT 99926405T AT E261441 T1 ATE261441 T1 AT E261441T1
Authority
AT
Austria
Prior art keywords
distamycin
analogues
production
acid derivatives
cinnamic acid
Prior art date
Application number
AT99926405T
Other languages
English (en)
Inventor
Paolo Cozzi
Pier Giovanni Baraldi
Italo Beria
Marina Caldarelli
Maria Cristina Geroni
Giulia Pennella
Romeo Romagnoli
Original Assignee
Pharmacia Italia Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacia Italia Spa filed Critical Pharmacia Italia Spa
Application granted granted Critical
Publication of ATE261441T1 publication Critical patent/ATE261441T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AT99926405T 1998-06-05 1999-05-22 Analoga von distamycin-zimtsäurederivaten, verfahren zu ihrer herstellung und ihre verwendung als antitumormittel ATE261441T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9812211.2A GB9812211D0 (en) 1998-06-05 1998-06-05 Cinnamoyl distamycin analogous derivatives,process for their preparation,and their use as antitumor agents
PCT/EP1999/003595 WO1999064413A1 (en) 1998-06-05 1999-05-22 Cinnamoyl distamycin analogous derivatives, process for their preparation, and their use as antitumor agents

Publications (1)

Publication Number Publication Date
ATE261441T1 true ATE261441T1 (de) 2004-03-15

Family

ID=10833321

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99926405T ATE261441T1 (de) 1998-06-05 1999-05-22 Analoga von distamycin-zimtsäurederivaten, verfahren zu ihrer herstellung und ihre verwendung als antitumormittel

Country Status (7)

Country Link
US (1) US6596845B1 (de)
EP (1) EP1084120B1 (de)
JP (1) JP2002517494A (de)
AT (1) ATE261441T1 (de)
DE (1) DE69915471D1 (de)
GB (1) GB9812211D0 (de)
WO (1) WO1999064413A1 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6559125B1 (en) 2000-01-28 2003-05-06 California Institute Of Technology Polyamide-alkylator conjugates and related products and method
CA2403537A1 (en) 2000-03-16 2001-10-11 Genesoft, Inc. Charged compounds comprising a nucleic acid binding moiety and uses therefor
US7078536B2 (en) 2001-03-14 2006-07-18 Genesoft Pharmaceuticals, Inc. Charged compounds comprising a nucleic acid binding moiety and uses therefor
US20030236198A1 (en) 2001-06-13 2003-12-25 Genesoft, Inc. Antipathogenic benzamide compounds
ATE425753T1 (de) 2002-08-02 2009-04-15 Genesoft Pharmaceuticals Inc Biaryl-verbindungen mit antiinfektiver wirkung
EP1562931A2 (de) 2002-10-25 2005-08-17 Genesoft Pharmaceuticals, Inc. Biarylverbindungen mitantiinfektionswirkung
JP2006509027A (ja) 2002-12-10 2006-03-16 オーシェント ファーマシューティカルズ コーポレーション （ピロールカルボキサミド）−（ベンズアミド）−（イミダゾールカルボキサミド）モチーフを有する抗菌化合物

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9416005D0 (en) 1994-08-08 1994-09-28 Erba Carlo Spa Peptidic compounds analogous to distamycin a and process for their preparation
GB9610079D0 (en) 1996-05-14 1996-07-17 Pharmacia Spa Distamycin deriratives process for preparing them and their use as antitumor and antiviral agents

Also Published As

Publication number Publication date
DE69915471D1 (de) 2004-04-15
JP2002517494A (ja) 2002-06-18
GB9812211D0 (en) 1998-08-05
EP1084120A1 (de) 2001-03-21
EP1084120B1 (de) 2004-03-10
WO1999064413A1 (en) 1999-12-16
US6596845B1 (en) 2003-07-22

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Legal Events

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