ATE261948T1 - 2-aminothiazol-kondensierte 2-aminoindane und 2- aminotetraline, sowie deren verwendung - Google Patents

2-aminothiazol-kondensierte 2-aminoindane und 2- aminotetraline, sowie deren verwendung

Info

Publication number: ATE261948T1
Authority: AT; Austria
Prior art keywords: carbon atoms; alkyl; aminotetralines; aminoindanes; aminothiazole
Prior art date: 1998-07-01

Application number

AT99935232T

Other languages

English (en)

Inventor

H Kan Vilhelm Wikstroem

Per Erik Andren

Per Arvid Emil Carlsson

Durk Dijkstra

Lars Gunne

Vliet Leonard Alexander Van

Original Assignee

Wikstroem Hakan Vilhelm

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-07-01

Filing date

1999-07-01

Publication date

2004-04-15

1999-07-01 Application filed by Wikstroem Hakan Vilhelm filed Critical Wikstroem Hakan Vilhelm

2004-04-15 Application granted granted Critical

2004-04-15 Publication of ATE261948T1 publication Critical patent/ATE261948T1/de

Links

RAIPHJJURHTUIC-UHFFFAOYSA-N 1,3-thiazol-2-amine Chemical compound NC1=NC=CS1 RAIPHJJURHTUIC-UHFFFAOYSA-N 0.000 title 1
125000004432 carbon atom Chemical group C* 0.000 abstract 4
125000000217 alkyl group Chemical group 0.000 abstract 3
LCGFVWKNXLRFIF-UHFFFAOYSA-N 1,2,3,4-tetrahydronaphthalen-2-amine Chemical class C1=CC=C2CC(N)CCC2=C1 LCGFVWKNXLRFIF-UHFFFAOYSA-N 0.000 abstract 1
HBAQYPYDRFILMT-UHFFFAOYSA-N 8-[3-(1-cyclopropylpyrazol-4-yl)-1H-pyrazolo[4,3-d]pyrimidin-5-yl]-3-methyl-3,8-diazabicyclo[3.2.1]octan-2-one Chemical class C1(CC1)N1N=CC(=C1)C1=NNC2=C1N=C(N=C2)N1C2C(N(CC1CC2)C)=O HBAQYPYDRFILMT-UHFFFAOYSA-N 0.000 abstract 1
239000002253 acid Substances 0.000 abstract 1
125000003342 alkenyl group Chemical group 0.000 abstract 1
125000000304 alkynyl group Chemical group 0.000 abstract 1
125000003710 aryl alkyl group Chemical group 0.000 abstract 1
125000003118 aryl group Chemical group 0.000 abstract 1
210000003169 central nervous system Anatomy 0.000 abstract 1
125000000753 cycloalkyl group Chemical group 0.000 abstract 1
230000003291 dopaminomimetic effect Effects 0.000 abstract 1
239000003814 drug Substances 0.000 abstract 1
230000000694 effects Effects 0.000 abstract 1
125000001188 haloalkyl group Chemical group 0.000 abstract 1
125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
239000008194 pharmaceutical composition Substances 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/36—Opioid-abuse
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
- C07D277/84—Naphthothiazoles

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Neurosurgery (AREA)
Pharmacology & Pharmacy (AREA)
Neurology (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Chemical Kinetics & Catalysis (AREA)
Biomedical Technology (AREA)
Psychiatry (AREA)
Addiction (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Psychology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Agricultural Chemicals And Associated Chemicals (AREA)

AT99935232T 1998-07-01 1999-07-01 2-aminothiazol-kondensierte 2-aminoindane und 2- aminotetraline, sowie deren verwendung ATE261948T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
SE9802360A SE9802360D0 (sv)	1998-07-01	1998-07-01	New 2-aminothiazol-fused 2-aminoindans and 2-aminotetralins ((basic)-N-substituted and (basic)-N,N-disubstituted derivatives of 2,6-diamino-thiazolo(4,5-f)indan and 2,7-di-amino-thiazolo(4,5-g)tetralin
PCT/SE1999/001197 WO2000001680A1 (en)	1998-07-01	1999-07-01	New 2-aminothiazol-fused 2-aminoindans and 2-aminotetralins and their use

Publications (1)

Publication Number	Publication Date
ATE261948T1 true ATE261948T1 (de)	2004-04-15

Family

ID=20411925

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT99935232T ATE261948T1 (de)	1998-07-01	1999-07-01	2-aminothiazol-kondensierte 2-aminoindane und 2- aminotetraline, sowie deren verwendung

Country Status (15)

Country	Link
US (1)	US6291494B1 (de)
EP (1)	EP1091946B1 (de)
JP (1)	JP4714341B2 (de)
CN (1)	CN1126747C (de)
AT (1)	ATE261948T1 (de)
AU (1)	AU745550B2 (de)
CA (1)	CA2335560C (de)
CZ (1)	CZ298751B6 (de)
DE (1)	DE69915623T2 (de)
HU (1)	HUP0104723A3 (de)
NZ (1)	NZ508852A (de)
PL (1)	PL202397B1 (de)
SE (1)	SE9802360D0 (de)
WO (1)	WO2000001680A1 (de)
ZA (1)	ZA200007454B (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE60113407T2 (de) *	2000-05-04	2006-06-29	Warner-Lambert Co. Llc	Verfahren zur hemmung von amyloidprotein aggregation und zur diagnostischen nachweis von amyloidablagerung unter verwendung von aminoindanderivaten
WO2005084205A2 (en) *	2004-02-27	2005-09-15	Teva Pharmaceutical Industries, Ltd.	Diamino thiazoloindan derivatives and their use
US20050197365A1 (en) *	2004-02-27	2005-09-08	Jeffrey Sterling	Diamino thiazoloindan derivatives and their use
WO2006043532A1 (ja) *	2004-10-19	2006-04-27	Ono Pharmaceutical Co., Ltd.	パーキンソン病治療剤
AR061478A1 (es) *	2006-06-19	2008-08-27	Takeda Pharmaceutical	Compuesto triciclico y composicion farmaceutica
SA109300120B1 (ar) *	2008-02-21	2011-10-08	استرازينيكا ايه بي	مركب (R)- N6- إيثيل- 6، 7- داي هيدرو- 5H- إندينو [5، 6- d] ثيازول- 2، 6- داي أمين وأستخدامة كمضاد لحالات الذهان
CN114929178B (zh) *	2019-12-17	2024-07-30	登士柏德萃有限公司	牙科根管填充组合物
CN116209657A (zh) *	2020-08-06	2023-06-02	泰科根公司	用于精神障碍或增强的2-氨基茚满化合物

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US2055609A (en)	1934-11-03	1936-09-29	Du Pont	Ar-tetrahydro-naphthothiazoles
DE3447075A1 (de) *	1984-12-22	1986-07-03	Dr. Karl Thomae Gmbh, 7950 Biberach	Tetrahydro-benzthiazole, deren herstellung und deren verwendung als zwischenprodukte oder als arzneimittel
DE3572485D1 (en)	1984-12-22	1989-09-28	Thomae Gmbh Dr K	Tetrahydro-benzothiazoles, their production and their use as intermediates or drugs
US4826860A (en) *	1987-03-16	1989-05-02	Warner-Lambert Company	Substituted 2-aminobenzothiazoles and derivatives useful as cerebrovascular agents

1998
- 1998-07-01 SE SE9802360A patent/SE9802360D0/xx unknown
1999
- 1999-07-01 AT AT99935232T patent/ATE261948T1/de not_active IP Right Cessation
- 1999-07-01 US US09/720,911 patent/US6291494B1/en not_active Expired - Fee Related
- 1999-07-01 JP JP2000558085A patent/JP4714341B2/ja not_active Expired - Fee Related
- 1999-07-01 WO PCT/SE1999/001197 patent/WO2000001680A1/en not_active Ceased
- 1999-07-01 PL PL345066A patent/PL202397B1/pl not_active IP Right Cessation
- 1999-07-01 CZ CZ20004807A patent/CZ298751B6/cs not_active IP Right Cessation
- 1999-07-01 DE DE69915623T patent/DE69915623T2/de not_active Expired - Lifetime
- 1999-07-01 HU HU0104723A patent/HUP0104723A3/hu unknown
- 1999-07-01 EP EP99935232A patent/EP1091946B1/de not_active Expired - Lifetime
- 1999-07-01 CA CA002335560A patent/CA2335560C/en not_active Expired - Fee Related
- 1999-07-01 AU AU50751/99A patent/AU745550B2/en not_active Ceased
- 1999-07-01 CN CN99808052A patent/CN1126747C/zh not_active Expired - Fee Related
- 1999-07-01 NZ NZ508852A patent/NZ508852A/xx not_active IP Right Cessation
2000
- 2000-12-13 ZA ZA200007454A patent/ZA200007454B/en unknown

Also Published As

Publication number	Publication date
JP2002519414A (ja)	2002-07-02
WO2000001680A1 (en)	2000-01-13
CA2335560C (en)	2008-06-03
US6291494B1 (en)	2001-09-18
ZA200007454B (en)	2001-06-14
CN1126747C (zh)	2003-11-05
HUP0104723A3 (en)	2004-10-28
DE69915623T2 (de)	2005-02-03
PL345066A1 (en)	2001-12-03
NZ508852A (en)	2002-10-25
CA2335560A1 (en)	2000-01-13
JP4714341B2 (ja)	2011-06-29
EP1091946B1 (de)	2004-03-17
HUP0104723A2 (hu)	2002-04-29
DE69915623D1 (de)	2004-04-22
SE9802360D0 (sv)	1998-07-01
AU745550B2 (en)	2002-03-21
AU5075199A (en)	2000-01-24
CN1307569A (zh)	2001-08-08
EP1091946A1 (de)	2001-04-18
PL202397B1 (pl)	2009-06-30
CZ298751B6 (cs)	2008-01-16
CZ20004807A3 (cs)	2001-11-14

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Legal Events

Date	Code	Title	Description
2004-09-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties