ATE261975T1 - Derivate des carbamates und thiocarbamates von podophyllotoxin, ihre herstellungsweise und pharmazeutische zusammensetzungen, die diese enthalten - Google Patents

Derivate des carbamates und thiocarbamates von podophyllotoxin, ihre herstellungsweise und pharmazeutische zusammensetzungen, die diese enthalten

Info

Publication number
ATE261975T1
ATE261975T1 AT01947525T AT01947525T ATE261975T1 AT E261975 T1 ATE261975 T1 AT E261975T1 AT 01947525 T AT01947525 T AT 01947525T AT 01947525 T AT01947525 T AT 01947525T AT E261975 T1 ATE261975 T1 AT E261975T1
Authority
AT
Austria
Prior art keywords
podophyllotoxin
thiocarbamate
carbamate
derivatives
production
Prior art date
Application number
AT01947525T
Other languages
English (en)
Inventor
Claude Monneret
Emmanuel Bertounesque
Philippe Meresse
Ghanem Atassi
Alain Pierre
John Hickman
Bruno Pfeiffer
Pierre Renard
Original Assignee
Servier Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Servier Lab filed Critical Servier Lab
Application granted granted Critical
Publication of ATE261975T1 publication Critical patent/ATE261975T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AT01947525T 2000-06-20 2001-06-19 Derivate des carbamates und thiocarbamates von podophyllotoxin, ihre herstellungsweise und pharmazeutische zusammensetzungen, die diese enthalten ATE261975T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0007823A FR2810321B1 (fr) 2000-06-20 2000-06-20 Nouveaux derives de podophyllotoxine carbamate et thiocarbamate, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
PCT/FR2001/001908 WO2001098307A1 (fr) 2000-06-20 2001-06-19 Derives de podophyllotoxine carbamate et thiocarbamate, leur procede de preparation et les compositions pharmaceutiques qui les contiennent

Publications (1)

Publication Number Publication Date
ATE261975T1 true ATE261975T1 (de) 2004-04-15

Family

ID=8851423

Family Applications (1)

Application Number Title Priority Date Filing Date
AT01947525T ATE261975T1 (de) 2000-06-20 2001-06-19 Derivate des carbamates und thiocarbamates von podophyllotoxin, ihre herstellungsweise und pharmazeutische zusammensetzungen, die diese enthalten

Country Status (25)

Country Link
US (1) US6878746B2 (de)
EP (1) EP1292597B1 (de)
JP (1) JP3909017B2 (de)
KR (1) KR100513575B1 (de)
CN (1) CN1191257C (de)
AR (1) AR028961A1 (de)
AT (1) ATE261975T1 (de)
AU (2) AU6919001A (de)
BR (1) BR0111854A (de)
CA (1) CA2413515C (de)
CZ (1) CZ2003172A3 (de)
DE (1) DE60102378T2 (de)
DK (1) DK1292597T3 (de)
EA (1) EA005200B1 (de)
ES (1) ES2217159T3 (de)
FR (1) FR2810321B1 (de)
HU (1) HUP0301612A3 (de)
MX (1) MXPA02012570A (de)
NO (1) NO20026004L (de)
PL (1) PL359460A1 (de)
PT (1) PT1292597E (de)
SK (1) SK682003A3 (de)
TR (1) TR200400592T4 (de)
WO (1) WO2001098307A1 (de)
ZA (1) ZA200209639B (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7087641B2 (en) * 2002-03-28 2006-08-08 Council Of Scientific & Industrial Research 4β-1″-[(2″-substituted benzoyl) anilino]podophyllotoxin analogues useful as anticancer agents
FR2869035B1 (fr) 2004-04-16 2006-07-14 Pierre Fabre Medicament Sa Derives (poly)aminoalkylaminoacetamide d'epipodophyllotoxine leur procede de preparation et leurs applications en therapeutique comme agent anticancereux
KR101975843B1 (ko) * 2008-05-23 2019-05-09 더 유니버시티 오브 브리티쉬 콜롬비아 리포좀 나노입자에 사용하기 위한 변형된 약물
FR2935143B1 (fr) 2008-08-19 2010-12-03 Pf Medicament Nouveaus derives (poly)aminoalkylaminoalkylamides, alkyl-urees, ou alkyl-sulfonamides d'epipodophyllotoxine, leur procede de preparation et leur application en therapeuthique comme agent cancereux
JP2013530993A (ja) 2010-07-02 2013-08-01 アンジオケム インコーポレーテッド 治療用コンジュゲートのための短く且つｄ−アミノ酸を含有するポリペプチドおよびその使用
CN107964014A (zh) * 2017-10-28 2018-04-27 兰州大学 一种邻硝基芳酰化衍生物类化合物、制备方法及其应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES319647A1 (es) * 1964-11-18 1966-08-01 Sandoz Ag Procedimiento para la preparaciën de derivados de la podofilotoxina
JPH01117885A (ja) * 1987-10-30 1989-05-10 Dai Ichi Seiyaku Co Ltd 新規ボドフィロトキシン誘導体及びその製造法
US6566393B1 (en) * 2002-06-21 2003-05-20 The University Of North Carolina At Chapel Hill Etoposide analogs and methods of use thereof

Also Published As

Publication number Publication date
EA005200B1 (ru) 2004-12-30
HK1055424A1 (en) 2004-01-09
DK1292597T3 (da) 2004-07-12
KR20030025246A (ko) 2003-03-28
CZ2003172A3 (cs) 2003-05-14
WO2001098307A1 (fr) 2001-12-27
JP2004501158A (ja) 2004-01-15
EP1292597A1 (de) 2003-03-19
US20040101574A1 (en) 2004-05-27
AU2001269190B2 (en) 2005-03-17
CA2413515C (fr) 2008-02-05
FR2810321A1 (fr) 2001-12-21
HUP0301612A2 (hu) 2003-09-29
CN1437604A (zh) 2003-08-20
NO20026004D0 (no) 2002-12-13
KR100513575B1 (ko) 2005-09-09
PL359460A1 (en) 2004-08-23
CA2413515A1 (fr) 2001-12-27
EP1292597B1 (de) 2004-03-17
MXPA02012570A (es) 2003-04-10
CN1191257C (zh) 2005-03-02
ZA200209639B (en) 2003-11-27
ES2217159T3 (es) 2004-11-01
AU6919001A (en) 2002-01-02
BR0111854A (pt) 2003-05-13
EA200300029A1 (ru) 2003-06-26
DE60102378D1 (de) 2004-04-22
SK682003A3 (en) 2003-05-02
TR200400592T4 (tr) 2004-04-21
US6878746B2 (en) 2005-04-12
PT1292597E (pt) 2004-06-30
HUP0301612A3 (en) 2005-08-29
NO20026004L (no) 2002-12-13
JP3909017B2 (ja) 2007-04-25
AR028961A1 (es) 2003-05-28
DE60102378T2 (de) 2005-02-24
FR2810321B1 (fr) 2002-07-26

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