ATE264692T1 - Verwendung von no synthase hemmern und fängern von reaktiven sauerstoffsformen zur behandlung von ischämie - Google Patents
Verwendung von no synthase hemmern und fängern von reaktiven sauerstoffsformen zur behandlung von ischämieInfo
- Publication number
- ATE264692T1 ATE264692T1 AT97940183T AT97940183T ATE264692T1 AT E264692 T1 ATE264692 T1 AT E264692T1 AT 97940183 T AT97940183 T AT 97940183T AT 97940183 T AT97940183 T AT 97940183T AT E264692 T1 ATE264692 T1 AT E264692T1
- Authority
- AT
- Austria
- Prior art keywords
- caughters
- reactive oxygen
- synthase inhibitors
- oxygen forms
- treat ischemia
- Prior art date
Links
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical group [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 title abstract 3
- 239000003112 inhibitor Substances 0.000 title 1
- 208000028867 ischemia Diseases 0.000 title 1
- 239000000126 substance Substances 0.000 abstract 4
- 230000002401 inhibitory effect Effects 0.000 abstract 2
- 229910052760 oxygen Inorganic materials 0.000 abstract 2
- 239000001301 oxygen Substances 0.000 abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Cardiology (AREA)
- Communicable Diseases (AREA)
- Epidemiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Oncology (AREA)
- Vascular Medicine (AREA)
- Pain & Pain Management (AREA)
- Virology (AREA)
- Toxicology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Urology & Nephrology (AREA)
- Rheumatology (AREA)
- Immunology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9610875A FR2753098B1 (fr) | 1996-09-06 | 1996-09-06 | Composition pharmaceutique comprenant au moins un inhibiteur de no synthase et au moins un piegeur des formes reactives de l'oxygene |
| PCT/FR1997/001567 WO1998009653A1 (fr) | 1996-09-06 | 1997-09-05 | Association inhibiteurs de no synthase et piegeurs des formes reactives de l'oxygene |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE264692T1 true ATE264692T1 (de) | 2004-05-15 |
Family
ID=9495505
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT97940183T ATE264692T1 (de) | 1996-09-06 | 1997-09-05 | Verwendung von no synthase hemmern und fängern von reaktiven sauerstoffsformen zur behandlung von ischämie |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US6297281B1 (de) |
| EP (1) | EP0939654B1 (de) |
| JP (1) | JP2000517336A (de) |
| AT (1) | ATE264692T1 (de) |
| AU (1) | AU734296B2 (de) |
| CA (1) | CA2264901C (de) |
| DE (1) | DE69728782T2 (de) |
| ES (1) | ES2221066T3 (de) |
| FR (1) | FR2753098B1 (de) |
| IL (1) | IL128801A (de) |
| NO (1) | NO991100L (de) |
| NZ (1) | NZ334597A (de) |
| RU (1) | RU2174844C2 (de) |
| WO (1) | WO1998009653A1 (de) |
Families Citing this family (46)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20030017998A1 (en) * | 1997-05-16 | 2003-01-23 | Snow Alan D. | Proanthocyanidins for the treatment of amyloid and alpha-synuclein diseases |
| EP1068868A3 (de) * | 1997-07-08 | 2001-01-31 | Rath, Matthias, Dr. med. | Synergistischer Zusammensetzung, der Ascorbat und Lysin für Zustände enthält zur Behandlung extrazellularer Matrixdegeneration |
| WO1999026657A1 (en) * | 1997-11-25 | 1999-06-03 | Musc Foundation For Research Development | Inhibitors of nitric oxide synthase |
| EP1096950B1 (de) * | 1998-07-10 | 2003-09-10 | Duke University | Anwendung der hemoproteine in der therapie |
| FR2783519B1 (fr) | 1998-09-23 | 2003-01-24 | Sod Conseils Rech Applic | Nouveaux derives d'amidines, leur preparation, leur application a titre de medicaments et les compositions pharmaceutiques les contenant |
| GB9827393D0 (en) * | 1998-12-11 | 1999-02-03 | Univ London | Treatment of erectile dysfunction in diabetes patients |
| FR2787447B1 (fr) * | 1998-12-18 | 2001-03-23 | Centre Nat Rech Scient | Nouveaux derives de melatonine et medicament comprenant de tels derives |
| EP1013272A1 (de) * | 1998-12-23 | 2000-06-28 | Biomedical Primate Research Centre (BPRC) | Beeinflussung der Aktivität eines Stickoxidradikalherstellungsweges zur Behandlung von mit freien Sauerstoffradikalen verbundenen Krankheiten |
| US6075045A (en) * | 1999-04-28 | 2000-06-13 | Ajinomoto Co., Inc. | Method of treating paralysis of the extremities caused by cerebral infarction |
| DE19962267A1 (de) * | 1999-12-23 | 2001-06-28 | Beiersdorf Ag | Verwendung von Wirkstoffkombinationen aus einem oder mehreren NO-Synthasehemmern und einer oder mehreren Ascorbylverbindungen zur Stärkung der Barrierefunktion der Haut |
| EP1808169B8 (de) * | 1999-12-30 | 2012-07-04 | Proteotech Inc. | Polyhydroxylierte aromatische Verbindungen zur Behandlung von Amyloidose und $g(a)-Synuklein-Fibrillen-Erkrankungen |
| US20010047032A1 (en) * | 1999-12-30 | 2001-11-29 | Castillo Gerardo M. | Polyhydroxylated aromatic compounds for the treatment of amyloidosis and alpha-synuclein fibril diseases |
| DE10000840A1 (de) * | 2000-01-12 | 2001-07-19 | Beiersdorf Ag | Verwendung eines oder mehrerer NO-Synthasehemmer |
| IL152792A0 (en) * | 2000-06-08 | 2003-06-24 | Univ Texas | Heterocycle derivatives and methods of use |
| AU2001268422A1 (en) * | 2000-06-15 | 2001-12-24 | University Of Kentucky Research Foundation | Agmatine and agmatine analogs in the treatment of epilepsy, seizure, and electroconvulsive disorders |
| DK1315505T3 (da) * | 2000-09-05 | 2008-03-03 | Meditor Pharmaceuticals Ltd | Farmaceutiske præparater mod hovedpine, migræne, kvalme og emesis |
| US20070208087A1 (en) | 2001-11-02 | 2007-09-06 | Sanders Virginia J | Compounds, compositions and methods for the treatment of inflammatory diseases |
| US7034054B2 (en) * | 2000-12-15 | 2006-04-25 | Galileo Pharmaceuticals, Inc. | Methods for the prevention and treatment of cerebral ischemia using non-alpha tocopherols |
| CH694549A5 (de) | 2001-01-16 | 2005-03-31 | Dr Matthias Rath | Verwendung einer synergistischen Zusammensetzung, die Ascorbat und Lysin für Zustände enthält zur Behandlung extrazellularer Matrixdegeration. |
| DE10111054A1 (de) * | 2001-03-06 | 2002-09-12 | Beiersdorf Ag | Verwendung von Substanzen, die verhindern, daß die NO-Synthese des warmblütigen Organismus ihre Wirkung entfaltet, zur Herstellung von kosmetischen oder dermatologischen Zubereitungen zur Stärkung der Barrierefunktion der Haut |
| DE10111050A1 (de) * | 2001-03-06 | 2002-09-12 | Beiersdorf Ag | Verwendung von Substanzen, die verhindern, daß die NO-Synthase des warmblütigenOrganismus ihre Wirkung entfaltet, zur Herstellung von kosmetischewn oder dermatologischen Zubereitungen zur Behandlung und/oder Prophylaxe unerwünschter Hautpigmentierung |
| DE10111049A1 (de) * | 2001-03-06 | 2002-09-12 | Beiersdorf Ag | Verwendung von Substanzen, die verhindern, daß die NO-Synthese des warmblütigen Organismus ihre Wirkung entfaltet, zur Herstellung von kosmetischen oder dermatologischen Zubereitungen, zur Prophylaxe und Behandlung von entzündlichen Hautzuständen und/oder zum Hautschutz bei empfindlich determinierter trockener Haut |
| DE10111052A1 (de) * | 2001-03-06 | 2002-09-12 | Beiersdorf Ag | Verwendung von Substanzen, die verhindern, daß die NO-Synthase des warmblütigen Organismus ihre Wirkung entfaltet, zur Herstellung von kosmetischen oder dermatologischen Zubereitungen zur Steigerung der Ceramidbiosynthese |
| WO2003039540A2 (en) * | 2001-11-09 | 2003-05-15 | Sepracor Inc. | D-amino acid oxidase inhibitors for learning and memory |
| DE10219644A1 (de) * | 2002-05-02 | 2003-11-20 | Johannes Wohlrab | Verwendung vom Agmatin zur topischen Applikation |
| SI1511710T1 (sl) | 2002-05-31 | 2014-04-30 | Proteotech, Inc. | Spojine, sestavki in postopki za zdravljenje amiloidnih bolezni in sinukleinopatij, kot je Alzheimerjeva bolezen, diabetes tipa 2 in Parkinsova bolezen |
| GB0214147D0 (en) * | 2002-06-19 | 2002-07-31 | Glaxo Group Ltd | Formulations |
| EP1790648A1 (de) * | 2002-10-11 | 2007-05-30 | Proteotech, Inc. | Verwendung von Procyanidin B2 und dessen Verwendung zur Herstellung eines Medikaments zur Behandlung von amyloid- und synucleinbasierten Krankheiten |
| US20050234026A1 (en) * | 2003-11-10 | 2005-10-20 | Weinberg Joe B | Method and agent for inducing apoptosis/cell death in leukemia cells |
| US20090186929A1 (en) * | 2003-11-10 | 2009-07-23 | U.S. Department Of Veterans Affairs | Method and agent for inducing apoptosis/cell death in leukemia cells |
| RU2361862C2 (ru) | 2003-12-29 | 2009-07-20 | Сепракор Инк. | Пиррольные и пиразольные ингибиторы daao |
| WO2006002082A2 (en) * | 2004-06-16 | 2006-01-05 | Jack Arbiser | Carbazole formulations for the treatment of psoriasis and angiogenesis |
| CA2598792A1 (en) | 2005-03-02 | 2006-09-08 | Metanomics Gmbh | Process for the production of fine chemicals |
| US8283327B2 (en) | 2005-03-19 | 2012-10-09 | Kneller Bruce W | Palatinose for enhancing dietary supplement and pharmaceutical delivery |
| PT2471530T (pt) | 2005-06-01 | 2017-04-19 | Edison Pharmaceuticals Inc | Produtos terapêuticos com atividade redox para o tratamento de doenças mitocondriais e de outras condições e modulação de biomarcadores energéticos |
| WO2007004523A1 (ja) * | 2005-07-04 | 2007-01-11 | Tokyo Medical And Dental University | L-アルギニン含有医薬組成物及び飲食品用組成物 |
| EP1986636B1 (de) | 2006-02-22 | 2013-04-24 | Edison Pharmaceuticals, Inc. | Phenol- und 1,4-benzochinon-derivate zur verwendung in der behandlung von erkrankungen der mitochondrien |
| US7884124B2 (en) * | 2006-06-30 | 2011-02-08 | Sepracor Inc. | Fluoro-substituted inhibitors of D-amino acid oxidase |
| US7579370B2 (en) * | 2006-06-30 | 2009-08-25 | Sepracor Inc. | Fused heterocycles |
| US8314153B2 (en) | 2008-09-10 | 2012-11-20 | Edison Pharmaceuticals, Inc. | Treatment of pervasive developmental disorders with redox-active therapeutics |
| EP2273273A1 (de) | 2009-07-11 | 2011-01-12 | Rheinische Friedrich-Wilhelms-Universität Bonn | Inhibitoren der Nitrierung von Amyloid-ß-Peptiden und ihre Verwendung bei der Diagnose und Behandlung von Morbus Alzheimer |
| SI2470168T1 (en) * | 2009-08-26 | 2018-05-31 | Bioelectron Technology Corporation | Procedures for the prevention and treatment of brain ischemia |
| JP6411215B2 (ja) * | 2011-11-22 | 2018-10-24 | ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア | 虚血傷害を治療するためのシステアミンおよび/またはシスタミン |
| UA119032C2 (uk) * | 2012-10-02 | 2019-04-25 | Женеро Са | Фармацевтична композиція для лікування блокади ремієлінізації при захворюваннях, які пов'язані з експресією білка оболонки herv-w |
| WO2017106803A1 (en) | 2015-12-17 | 2017-06-22 | Bioelectron Technology Corporation | Flouroalkyl, flouroalkoxy, phenoxy, heteroaryloxy, alkoxy, and amine 1,4-benzoquinone derivatives for treatment of oxidative stress disorders |
| CN119054693B (zh) * | 2024-07-17 | 2025-09-12 | 中国农业科学院麻类研究所 | 一种芥子酸植物生长调节剂及其应用 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9320484D0 (en) * | 1993-10-05 | 1993-11-24 | Wellcome Found | Pharmaceutical combinations |
| EP0729356A1 (de) * | 1993-11-17 | 1996-09-04 | Duke University Medical Center | Verwendung von stickstoffoxid-synthase-inhibitoren zur behandlung von autoimmunerkrankungen |
| DE69425287T2 (de) * | 1994-11-15 | 2001-03-15 | Moreno Paolini | N-hydroxypiperidine als superoxid-radikalfänger |
-
1996
- 1996-09-06 FR FR9610875A patent/FR2753098B1/fr not_active Expired - Fee Related
-
1997
- 1997-09-05 WO PCT/FR1997/001567 patent/WO1998009653A1/fr not_active Ceased
- 1997-09-05 EP EP97940183A patent/EP0939654B1/de not_active Expired - Lifetime
- 1997-09-05 RU RU99106792/14A patent/RU2174844C2/ru not_active IP Right Cessation
- 1997-09-05 AT AT97940183T patent/ATE264692T1/de not_active IP Right Cessation
- 1997-09-05 DE DE69728782T patent/DE69728782T2/de not_active Expired - Fee Related
- 1997-09-05 ES ES97940183T patent/ES2221066T3/es not_active Expired - Lifetime
- 1997-09-05 NZ NZ334597A patent/NZ334597A/xx unknown
- 1997-09-05 US US09/254,254 patent/US6297281B1/en not_active Expired - Fee Related
- 1997-09-05 CA CA002264901A patent/CA2264901C/fr not_active Expired - Fee Related
- 1997-09-05 AU AU42111/97A patent/AU734296B2/en not_active Ceased
- 1997-09-05 JP JP10512314A patent/JP2000517336A/ja not_active Ceased
- 1997-09-05 IL IL12880197A patent/IL128801A/xx not_active IP Right Cessation
-
1999
- 1999-03-05 NO NO991100A patent/NO991100L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| NO991100L (no) | 1999-05-05 |
| IL128801A0 (en) | 2000-01-31 |
| IL128801A (en) | 2005-05-17 |
| AU734296B2 (en) | 2001-06-07 |
| NO991100D0 (no) | 1999-03-05 |
| DE69728782D1 (de) | 2004-05-27 |
| AU4211197A (en) | 1998-03-26 |
| JP2000517336A (ja) | 2000-12-26 |
| CA2264901A1 (fr) | 1998-03-12 |
| EP0939654B1 (de) | 2004-04-21 |
| FR2753098A1 (fr) | 1998-03-13 |
| DE69728782T2 (de) | 2005-04-28 |
| CA2264901C (fr) | 2006-01-03 |
| WO1998009653A1 (fr) | 1998-03-12 |
| ES2221066T3 (es) | 2004-12-16 |
| RU2174844C2 (ru) | 2001-10-20 |
| NZ334597A (en) | 2000-10-27 |
| FR2753098B1 (fr) | 1998-11-27 |
| US6297281B1 (en) | 2001-10-02 |
| EP0939654A1 (de) | 1999-09-08 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |