ATE267014T1 - Pyridomorphinanen und ihre verwendung - Google Patents
Pyridomorphinanen und ihre verwendungInfo
- Publication number
- ATE267014T1 ATE267014T1 AT00957402T AT00957402T ATE267014T1 AT E267014 T1 ATE267014 T1 AT E267014T1 AT 00957402 T AT00957402 T AT 00957402T AT 00957402 T AT00957402 T AT 00957402T AT E267014 T1 ATE267014 T1 AT E267014T1
- Authority
- AT
- Austria
- Prior art keywords
- pyridomorphinanes
- compounds
- formula
- treating
- immunomodulators
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 abstract 2
- 206010013654 Drug abuse Diseases 0.000 abstract 1
- JCXJVPUVTGWSNB-UHFFFAOYSA-N Nitrogen dioxide Chemical compound O=[N]=O JCXJVPUVTGWSNB-UHFFFAOYSA-N 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 229940035676 analgesics Drugs 0.000 abstract 1
- 239000000730 antalgic agent Substances 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 125000001475 halogen functional group Chemical group 0.000 abstract 1
- 239000002955 immunomodulating agent Substances 0.000 abstract 1
- 229940121354 immunomodulator Drugs 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 208000011117 substance-related disease Diseases 0.000 abstract 1
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/12—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
- C07D491/20—Spiro-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/36—Opioid-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Addiction (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Immunology (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Cosmetics (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US14858099P | 1999-08-13 | 1999-08-13 | |
| US21076000P | 2000-06-12 | 2000-06-12 | |
| PCT/US2000/022092 WO2001012196A1 (en) | 1999-08-13 | 2000-08-14 | Pyridomorphinans and use thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE267014T1 true ATE267014T1 (de) | 2004-06-15 |
Family
ID=26845980
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT00957402T ATE267014T1 (de) | 1999-08-13 | 2000-08-14 | Pyridomorphinanen und ihre verwendung |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US6465479B1 (de) |
| EP (1) | EP1200089B1 (de) |
| JP (1) | JP4763194B2 (de) |
| AT (1) | ATE267014T1 (de) |
| AU (1) | AU6902800A (de) |
| CA (1) | CA2380810C (de) |
| DE (1) | DE60010891T2 (de) |
| ES (1) | ES2222227T3 (de) |
| WO (1) | WO2001012196A1 (de) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10134038A1 (de) * | 2001-07-12 | 2003-02-06 | Hf Arzneimittelforsch Gmbh | Wirkstoff-Kombination zur medikamentösen Therapie der Nikotinabhängigkeit |
| JP2007504150A (ja) * | 2003-08-27 | 2007-03-01 | サザン・リサーチ・インスティテュート | ピリドモルヒナン(pyridomorphinan)類及びピリダジノモルヒナン(pyridazinomorphinan)類、並びに、それらの使用 |
| CN1298720C (zh) * | 2005-03-18 | 2007-02-07 | 中国科学院上海有机化学研究所 | C环连接有五元杂环的青藤碱衍生物和合成方法 |
| WO2006130471A1 (en) * | 2005-05-27 | 2006-12-07 | The Regents Of The University Of California | The use delta opioid receptor agonists and/or inverse agonists to inhibit the consumption of substances of abuse |
| AU2013256203B2 (en) * | 2012-05-02 | 2018-02-01 | Southern Research Institute | Heterocycle-fused morphinans, use thereof and preparation thereof |
| EP3089978B1 (de) | 2013-12-30 | 2018-08-29 | Purdue Pharma L.P. | Pyridonsulfonmorphinan-analoga als opioidrezeptorliganden |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4816586A (en) * | 1987-07-29 | 1989-03-28 | Regents Of The University Of Minnesota | Delta opioid receptor antagonists |
| US5223507A (en) * | 1992-01-21 | 1993-06-29 | G. D. Searle & Co. | Method of using opioid compounds as delta opioid selective agonist analgesics |
| IT1270612B (it) | 1994-07-14 | 1997-05-07 | Smithkline Beecham Farma | Derivati eterociclo-condensatori di morfinoidi |
| SE9402880D0 (sv) * | 1994-08-30 | 1994-08-30 | Astra Ab | New peptide derivatives |
| BR9707136A (pt) * | 1996-01-10 | 1999-08-31 | Smithkline Beecham Spa | Derivados morfinóides condesados em heterociclo (ii) |
-
2000
- 2000-08-14 AT AT00957402T patent/ATE267014T1/de active
- 2000-08-14 CA CA002380810A patent/CA2380810C/en not_active Expired - Fee Related
- 2000-08-14 DE DE60010891T patent/DE60010891T2/de not_active Expired - Lifetime
- 2000-08-14 JP JP2001516542A patent/JP4763194B2/ja not_active Expired - Fee Related
- 2000-08-14 WO PCT/US2000/022092 patent/WO2001012196A1/en not_active Ceased
- 2000-08-14 AU AU69028/00A patent/AU6902800A/en not_active Abandoned
- 2000-08-14 ES ES00957402T patent/ES2222227T3/es not_active Expired - Lifetime
- 2000-08-14 US US09/637,934 patent/US6465479B1/en not_active Expired - Lifetime
- 2000-08-14 EP EP00957402A patent/EP1200089B1/de not_active Expired - Lifetime
-
2002
- 2002-04-08 US US10/117,350 patent/US20030083499A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| AU6902800A (en) | 2001-03-13 |
| EP1200089A1 (de) | 2002-05-02 |
| US6465479B1 (en) | 2002-10-15 |
| JP2003507332A (ja) | 2003-02-25 |
| DE60010891T2 (de) | 2005-06-09 |
| CA2380810C (en) | 2006-03-14 |
| US20030083499A1 (en) | 2003-05-01 |
| DE60010891D1 (de) | 2004-06-24 |
| CA2380810A1 (en) | 2001-02-22 |
| ES2222227T3 (es) | 2005-02-01 |
| EP1200089A4 (de) | 2002-11-13 |
| EP1200089B1 (de) | 2004-05-19 |
| WO2001012196A1 (en) | 2001-02-22 |
| JP4763194B2 (ja) | 2011-08-31 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
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