ATE268329T1 - Aminomethylpyrrolidin-derivate mit aromatischen substituenten - Google Patents

Aminomethylpyrrolidin-derivate mit aromatischen substituenten

Info

Publication number
ATE268329T1
ATE268329T1 AT00907973T AT00907973T ATE268329T1 AT E268329 T1 ATE268329 T1 AT E268329T1 AT 00907973 T AT00907973 T AT 00907973T AT 00907973 T AT00907973 T AT 00907973T AT E268329 T1 ATE268329 T1 AT E268329T1
Authority
AT
Austria
Prior art keywords
group
hydrogen atom
alkyl
alkyl group
alkoxyl
Prior art date
Application number
AT00907973T
Other languages
English (en)
Inventor
Makoto Takemura
-Chome Kita-Kasai
Hisashi Takahashi
Katsuhiro Kawakami
Toshiyuki Takeda
Rie Miyauchi
Original Assignee
Daiichi Seiyaku Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Daiichi Seiyaku Co filed Critical Daiichi Seiyaku Co
Application granted granted Critical
Publication of ATE268329T1 publication Critical patent/ATE268329T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04—Ortho-condensed systems
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
AT00907973T 1999-03-10 2000-03-09 Aminomethylpyrrolidin-derivate mit aromatischen substituenten ATE268329T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP6280699 1999-03-10
PCT/JP2000/001439 WO2000053594A1 (en) 1999-03-10 2000-03-09 Aminomethylpyrrolidine derivatives having aromatic substituents

Publications (1)

Publication Number Publication Date
ATE268329T1 true ATE268329T1 (de) 2004-06-15

Family

ID=13210961

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00907973T ATE268329T1 (de) 1999-03-10 2000-03-09 Aminomethylpyrrolidin-derivate mit aromatischen substituenten

Country Status (10)

Country Link
US (2) US6762181B1 (de)
EP (1) EP1182202B1 (de)
KR (1) KR20010102560A (de)
CN (1) CN1258531C (de)
AT (1) ATE268329T1 (de)
AU (1) AU2940300A (de)
DE (1) DE60011264T2 (de)
NO (1) NO322011B1 (de)
RU (1) RU2255938C2 (de)
WO (1) WO2000053594A1 (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2940300A (en) * 1999-03-10 2000-09-28 Daiichi Pharmaceutical Co., Ltd. Aminomethylpyrrolidine derivatives having aromatic substituents
US7384773B1 (en) 2001-05-10 2008-06-10 Pfizer Inc Crystal of HIV protease-cleaved human beta secretase and method for crystallization thereof
US7012144B2 (en) * 2001-12-31 2006-03-14 Korea Research Institute Of Chemical Technology Quinolone carboxylic acid derivatives
US7915418B2 (en) 2003-06-06 2011-03-29 Daiichi Pharmaceutical Co., Ltd. Intermediates and process for the production of optically active quinolonecarboxylic acid derivatives
WO2005111030A1 (en) * 2004-05-12 2005-11-24 Warner-Lambert Company Llc Quinolone antibacterial agents
CN100441580C (zh) * 2006-07-14 2008-12-10 中山大学 喹啉二酮衍生物及其在制备抗菌药物中的应用
FR2928150A1 (fr) 2008-02-29 2009-09-04 Vetoquinol Sa Sa Nouveaux derives 7-substitues de 3-carboxy-oxadiazino-quinolones, leur preparation et leur application comme anti-bacteriens
EP2145891A1 (de) 2008-07-09 2010-01-20 Vetoquinol S.A. 9-substierte 5-Carboxy-Oxadiazin-Chinolon-Derivate, ihre Herstellung und ihre Anwendung als antibakterielle Mittel
US8987242B2 (en) 2008-12-05 2015-03-24 Merck Sharp & Dohme Corp. Morpholinone compounds as factor IXA inhibitors
JP2012511008A (ja) * 2008-12-05 2012-05-17 持田製薬株式会社 ＩＸａ因子阻害薬としてのモルホリノン化合物

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0207420B1 (de) 1985-06-26 1992-05-06 Daiichi Pharmaceutical Co., Ltd. Pyridoncarbonsäurederivate
JPH0723369B2 (ja) * 1986-12-27 1995-03-15 第一製薬株式会社 ピリドンカルボン酸誘導体
US4920120A (en) * 1988-01-25 1990-04-24 Warner-Lambert Company Antibacterial agents
IL90062A (en) * 1988-04-27 1994-10-07 Daiichi Seiyaku Co Pyridonecarboxylic acid derivatives, their preparation and pharmaceutical compositions containing them
US5157128A (en) * 1990-11-30 1992-10-20 Warner-Lambert Company Certain optically active substituted α,α-dialkyl-pyrrolidine-3-methamines useful as intermediates
DE4230804A1 (de) * 1992-09-15 1994-03-17 Bayer Ag 7-Isoindolinyl-chinolon- und -naphthyridon-Derivate
WO1996023782A1 (en) * 1995-02-02 1996-08-08 Daiichi Pharmaceutical Co., Ltd. Heterocyclic compounds
JP3833738B2 (ja) 1995-11-15 2006-10-18 第一製薬株式会社 置換アミノメチルピロリジン誘導体
JP4323574B2 (ja) * 1995-12-13 2009-09-02 大日本住友製薬株式会社 抗腫瘍剤
WO1997042954A1 (en) * 1996-05-10 1997-11-20 Pharmacia & Upjohn Company Topical administration of antimicrobial agents for the treatment of systemic bacterial diseases
JPH10324686A (ja) 1997-03-27 1998-12-08 Hokuriku Seiyaku Co Ltd ７−（ヒドロキシピロリジニル）キノリンカルボン酸誘導体
JPH10287669A (ja) * 1997-04-10 1998-10-27 Dai Ichi Seiyaku Co Ltd 置換アミノメチルピロリジン誘導体
AU2940300A (en) * 1999-03-10 2000-09-28 Daiichi Pharmaceutical Co., Ltd. Aminomethylpyrrolidine derivatives having aromatic substituents

Also Published As

Publication number Publication date
DE60011264D1 (de) 2004-07-08
CN1350527A (zh) 2002-05-22
NO20014374L (no) 2001-11-12
DE60011264T2 (de) 2005-07-14
US7186843B2 (en) 2007-03-06
NO322011B1 (no) 2006-08-07
KR20010102560A (ko) 2001-11-15
AU2940300A (en) 2000-09-28
US6762181B1 (en) 2004-07-13
NO20014374D0 (no) 2001-09-07
WO2000053594A1 (en) 2000-09-14
US20040209940A1 (en) 2004-10-21
EP1182202B1 (de) 2004-06-02
CN1258531C (zh) 2006-06-07
RU2255938C2 (ru) 2005-07-10
EP1182202A4 (de) 2002-03-27
EP1182202A1 (de) 2002-02-27

Similar Documents

Publication Publication Date Title
NL300927I1 (nl) tivozanib of een zout of hydraat ervan, in het bijzonder het hydrochloride-monohydraat
NO20015448L (no) Kinolinderivater som inhibitorer av MEK-enzymer
AU2003246100A1 (en) Amide derivative
CY1112899T1 (el) Παραγωγα θειαδιαζολινης για τη θεραπεια του καρκινου
DE69500542D1 (de) 11,21-Bisphenyl-19-nor-pregnan Derivate
DE69013959D1 (de) Aminobenzolsulfonsäurederivate.
ATE268329T1 (de) Aminomethylpyrrolidin-derivate mit aromatischen substituenten
AU2492500A (en) Aspartic protease inhibitors, compositions, and associated therapeutic methods
ATE315550T1 (de) Fungizide phenylamidinderivative
AU2001269540A1 (en) Serotonin reuptake inhibitors
PT1134219E (pt) Derivados de aminometilpirrolidina cicloalquil-substituidos
ATE283840T1 (de) Chondrogonese promotoren und indolin-2-on derivate
EP1034783A4 (de) Amidederivaten
WO2001044207A8 (fr) Nouveaux derives amino substitues ramifies du 3-amino-1-phenyl-1h[1,2 4]triazole, procedes pour leur preparation et compositions pharmaceutiques les contenant
DE69732635D1 (de) Cis-substituierte aminocyclopropanderivate
EP0995744A4 (de) Cis-substituierte fluoromethylpyrrolidin-derivate
ES2180975T3 (es) Derivados de cicloalquilaminometilpirrolidina.
IL151880A0 (en) Triazole derivatives and pharmaceutical compositions containing the same
DK0924213T3 (da) Pyrodobenzoxazinderivater
DK1433480T3 (da) Lægemiddel indeholdende pyrimidin-derivat
TW200508211A (en) 2-naphthylimino-1,3-thiazine derivatives
AU2002214266A1 (en) Carbamate derivatives, process for producing the same and use thereof

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties