ATE268782T1 - Zusammensetzungen zur wundheilung - Google Patents
Zusammensetzungen zur wundheilungInfo
- Publication number
- ATE268782T1 ATE268782T1 AT98963073T AT98963073T ATE268782T1 AT E268782 T1 ATE268782 T1 AT E268782T1 AT 98963073 T AT98963073 T AT 98963073T AT 98963073 T AT98963073 T AT 98963073T AT E268782 T1 ATE268782 T1 AT E268782T1
- Authority
- AT
- Austria
- Prior art keywords
- wound healing
- compositions
- angiotensin
- analogs
- mammals
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 2
- 230000029663 wound healing Effects 0.000 title abstract 2
- CZGUSIXMZVURDU-JZXHSEFVSA-N Ile(5)-angiotensin II Chemical compound C([C@@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC=1NC=NC=1)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CC=1C=CC=CC=1)C([O-])=O)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(N)=[NH2+])NC(=O)[C@@H]([NH3+])CC([O-])=O)C(C)C)C1=CC=C(O)C=C1 CZGUSIXMZVURDU-JZXHSEFVSA-N 0.000 abstract 2
- 102000005862 Angiotensin II Human genes 0.000 abstract 1
- 101800000733 Angiotensin-2 Proteins 0.000 abstract 1
- 241000124008 Mammalia Species 0.000 abstract 1
- 229950006323 angiotensin ii Drugs 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/14—Macromolecular materials
- A61L27/22—Polypeptides or derivatives thereof, e.g. degradation products
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/08—Peptides having 5 to 11 amino acids
- A61K38/085—Angiotensins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/22—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
- A61L15/32—Proteins, polypeptides; Degradation products or derivatives thereof, e.g. albumin, collagen, fibrin, gelatin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
- A61L26/0009—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form containing macromolecular materials
- A61L26/0028—Polypeptides; Proteins; Degradation products thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/14—Angiotensins: Related peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- Materials Engineering (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Vascular Medicine (AREA)
- Dermatology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Hematology (AREA)
- Immunology (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Transplantation (AREA)
- Gastroenterology & Hepatology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Peptides Or Proteins (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US6966297P | 1997-12-12 | 1997-12-12 | |
| PCT/US1998/026347 WO1999031125A1 (en) | 1997-12-12 | 1998-12-11 | Wound healing compositions |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE268782T1 true ATE268782T1 (de) | 2004-06-15 |
Family
ID=22090435
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT98963073T ATE268782T1 (de) | 1997-12-12 | 1998-12-11 | Zusammensetzungen zur wundheilung |
Country Status (9)
| Country | Link |
|---|---|
| US (3) | US6165978A (de) |
| EP (1) | EP1036089B1 (de) |
| JP (1) | JP4347522B2 (de) |
| AT (1) | ATE268782T1 (de) |
| AU (1) | AU755225B2 (de) |
| CA (1) | CA2315266C (de) |
| DE (1) | DE69824445T2 (de) |
| TW (1) | TW542843B (de) |
| WO (1) | WO1999031125A1 (de) |
Families Citing this family (42)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6528483B2 (en) | 1995-06-07 | 2003-03-04 | André Beaulieu | Method of producing concentrated non-buffered solutions of fibronectin |
| US7112320B1 (en) | 1995-06-07 | 2006-09-26 | Andre Beaulieu | Solid wound healing formulations containing fibronectin |
| US6335195B1 (en) * | 1997-01-28 | 2002-01-01 | Maret Corporation | Method for promoting hematopoietic and mesenchymal cell proliferation and differentiation |
| ATE268782T1 (de) * | 1997-12-12 | 2004-06-15 | Univ Southern California | Zusammensetzungen zur wundheilung |
| JP2002509077A (ja) | 1998-02-09 | 2002-03-26 | ユニヴァースティ オブ サザーン カリフォルニア | 赤血球形成促進方法 |
| WO1999058140A1 (en) * | 1998-05-11 | 1999-11-18 | University Of Southern California | Methods to increase white blood cell survival after chemotherapy |
| US6916783B2 (en) | 1998-07-13 | 2005-07-12 | University Of Southern California | Methods for accelerating bone and cartilage growth and repair |
| ATE250423T1 (de) | 1998-07-13 | 2003-10-15 | Univ Southern California | Verfahren zur beschleunigen den zuwachs und heilen von knochen und knorpel |
| AU755943B2 (en) | 1998-08-13 | 2003-01-02 | University Of Southern California | Methods to increase blood flow to ischemic tissue |
| US6730775B1 (en) | 1999-03-23 | 2004-05-04 | University Of Southern California | Methods for limiting scar and adhesion formation |
| US6821953B1 (en) | 1999-12-16 | 2004-11-23 | University Of Southern California | Methods for treating and preventing damage to mucosal tissue |
| WO2001055176A2 (en) * | 2000-01-27 | 2001-08-02 | University Of Southern California | Methods for inhibiting smooth muscle cell proliferation |
| US6747008B1 (en) | 2000-06-19 | 2004-06-08 | University Of Southern California | Methods for treating and preventing alopecia |
| AU2002308522A1 (en) * | 2001-05-01 | 2002-11-11 | University Of Southern California | Methods for inhibiting tumor cell proliferation |
| US7094252B2 (en) * | 2001-08-21 | 2006-08-22 | Cooltouch Incorporated | Enhanced noninvasive collagen remodeling |
| JP2005530768A (ja) | 2002-05-09 | 2005-10-13 | メディジーンズ | 血漿または血清を含有した創傷治療用医薬組成物 |
| DE10361306A1 (de) * | 2003-12-24 | 2005-07-28 | Lts Lohmann Therapie-Systeme Ag | Wundauflage und Wundschnellverband mit einem vasokonstriktorischen Inhaltsstoff, sowie Herstellungsverfahren hierfür |
| BRPI0602372B8 (pt) * | 2006-05-18 | 2021-06-22 | Einco Biomaterial Ltda | processo de preparação de compósitos em base de biocerâmicas e polímeros biodegradáveis e produto derivado |
| US20090227507A1 (en) * | 2008-03-10 | 2009-09-10 | University Of Southern California | Angiotensin (1-7) Dosage Forms and Uses Thereof |
| NZ594302A (en) * | 2008-12-29 | 2013-07-26 | Trevena Inc | Beta-arrestin effectors and compositions and methods of use thereof |
| WO2011120032A1 (en) * | 2010-03-26 | 2011-09-29 | University Of Southern California | Methods for treating combined radiation and thermal injury |
| US10279007B2 (en) | 2010-11-15 | 2019-05-07 | Oxygenetix Institute, Inc. | Topical treatment method for healing wounds, disinfecting, covering and concealing the wound until healing occurs |
| WO2012106427A2 (en) | 2011-02-02 | 2012-08-09 | University Of Southern California | Methods for treating diabetic foot ulcers |
| JP2015504870A (ja) * | 2011-12-16 | 2015-02-16 | タリックス ファーマシューティカルズ リミテッド | 線維症を処置するためのアンジオテンシン |
| WO2013116312A1 (en) | 2012-01-31 | 2013-08-08 | Trevena, Inc. | ß-ARRESTIN EFFECTORS AND COMPOSITIONS AND METHODS OF USE THEREOF |
| WO2013172956A1 (en) | 2012-05-14 | 2013-11-21 | University Of Southern California | Methods for limiting development of a skin wound |
| ES2834430T3 (es) | 2013-03-15 | 2021-06-17 | Univ Southern California | Procedimientos, compuestos y composiciones para el tratamiento de enfermedades relacionadas con la angiotensina |
| US9623084B2 (en) | 2013-03-15 | 2017-04-18 | University Of Southern California | Methods for treating multiple sclerosis |
| AU2014259948B2 (en) * | 2013-04-30 | 2019-04-18 | University Of Southern California | Accelerated healing of eye injuries by angiotensin peptides |
| AU2014284496A1 (en) | 2013-07-03 | 2016-01-21 | The Arizona Board Of Regents On Behalf Of The University Of Arizona | Method for treating cognitive dysfunction |
| US9518086B2 (en) | 2014-02-07 | 2016-12-13 | Trevena, Inc. | Crystalline and amorphous forms of a β-arrestin effector |
| AU2015264367A1 (en) | 2014-05-19 | 2016-12-15 | Trevena, Inc. | Synthesis of Beta-Arrestin Effectors |
| CN106535920B (zh) | 2014-07-21 | 2020-10-30 | 代表亚利桑那大学的亚利桑那校董会 | Ang-(1-7)衍生物寡肽及其使用和生产方法 |
| US10183055B2 (en) | 2014-07-21 | 2019-01-22 | Arizona Board Of Regents On Behalf Of The University Of Arizona | Ang-(1-7) derivative oligopeptides for the treatment of pain and other indications |
| WO2018002673A1 (en) | 2016-07-01 | 2018-01-04 | N4 Pharma Uk Limited | Novel formulations of angiotensin ii receptor antagonists |
| EP3548035A4 (de) | 2016-11-30 | 2020-07-22 | Case Western Reserve University | Kombinationen von 15-pgdh-inhibitoren mit corticosteroiden und/oder tnf-inhibitoren und verwendungen davon |
| CN110573154A (zh) | 2017-02-06 | 2019-12-13 | 卡斯西部储备大学 | 调节短链脱氢酶活性的组合物和方法 |
| WO2020106998A1 (en) | 2018-11-21 | 2020-05-28 | Case Western Reserve University | Compositions and methods of modulating short-chain dehydrogenase activity |
| KR102668789B1 (ko) | 2018-11-23 | 2024-05-24 | (주)메디코스바이오텍 | 창상치료용 약학조성물 |
| AU2021224268A1 (en) | 2020-02-21 | 2022-09-15 | Case Western Reserve University | Compositions and methods for treating renal injury |
| CR20220654A (es) | 2020-05-20 | 2023-08-24 | Rodeo Therapeutics Corp | Composiciones y métodos para modular la actividad de deshidrogenasas de cadena corta |
| AU2024381905A1 (en) | 2023-11-15 | 2026-06-25 | Xitra Therapeutics Gmbh | Small molecule modulators of mas and mrgd receptors |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5015629A (en) * | 1989-06-26 | 1991-05-14 | University Of Southern California | Tissue repair |
| EP1333034B1 (de) * | 1993-09-24 | 2010-07-14 | University Of Southern California | Verwendung von Angiotensin-II-Analogen zur Gewebewiederherstellung |
| PT730465E (pt) * | 1993-09-24 | 2002-06-28 | Univ Southern California | Utilizacao de angiotensina iii e de analogos desta em cicatrizacao de tecidos |
| US5955430A (en) * | 1993-09-24 | 1999-09-21 | University Of Southern California | Use of angiotensin II fragments and analogs thereof in tissue repair |
| US5834432A (en) * | 1995-06-06 | 1998-11-10 | The University Of Southern California | Use of angiotensin II Type 2 receptor agonists in tissue repair |
| US6110895A (en) * | 1996-12-16 | 2000-08-29 | University Of Southern California | Method of promoting healing in skin grafts |
| US6335195B1 (en) * | 1997-01-28 | 2002-01-01 | Maret Corporation | Method for promoting hematopoietic and mesenchymal cell proliferation and differentiation |
| AU6650098A (en) * | 1997-02-04 | 1998-08-25 | University Of Southern California | Method for accelerating healing of thermal injuries |
| ATE268782T1 (de) * | 1997-12-12 | 2004-06-15 | Univ Southern California | Zusammensetzungen zur wundheilung |
| AU755943B2 (en) * | 1998-08-13 | 2003-01-02 | University Of Southern California | Methods to increase blood flow to ischemic tissue |
-
1998
- 1998-12-11 AT AT98963073T patent/ATE268782T1/de not_active IP Right Cessation
- 1998-12-11 WO PCT/US1998/026347 patent/WO1999031125A1/en not_active Ceased
- 1998-12-11 US US09/210,249 patent/US6165978A/en not_active Expired - Lifetime
- 1998-12-11 CA CA002315266A patent/CA2315266C/en not_active Expired - Fee Related
- 1998-12-11 JP JP2000539048A patent/JP4347522B2/ja not_active Expired - Fee Related
- 1998-12-11 DE DE69824445T patent/DE69824445T2/de not_active Expired - Lifetime
- 1998-12-11 EP EP98963073A patent/EP1036089B1/de not_active Expired - Lifetime
- 1998-12-11 AU AU18177/99A patent/AU755225B2/en not_active Ceased
- 1998-12-14 TW TW087120706A patent/TW542843B/zh not_active IP Right Cessation
-
2000
- 2000-10-27 US US09/698,354 patent/US6455501B1/en not_active Expired - Lifetime
-
2002
- 2002-08-06 US US10/213,701 patent/US7022675B2/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| JP4347522B2 (ja) | 2009-10-21 |
| US20030017970A1 (en) | 2003-01-23 |
| US6455501B1 (en) | 2002-09-24 |
| CA2315266A1 (en) | 1999-06-24 |
| DE69824445D1 (de) | 2004-07-15 |
| EP1036089B1 (de) | 2004-06-09 |
| EP1036089A1 (de) | 2000-09-20 |
| WO1999031125B1 (en) | 1999-08-19 |
| TW542843B (en) | 2003-07-21 |
| CA2315266C (en) | 2004-08-10 |
| JP2002508391A (ja) | 2002-03-19 |
| AU755225B2 (en) | 2002-12-05 |
| DE69824445T2 (de) | 2005-06-30 |
| US7022675B2 (en) | 2006-04-04 |
| AU1817799A (en) | 1999-07-05 |
| WO1999031125A1 (en) | 1999-06-24 |
| US6165978A (en) | 2000-12-26 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |