ATE277601T1 - Verbesserungen bezüglich der verkapselung bioaktiver wirkstoffe - Google Patents
Verbesserungen bezüglich der verkapselung bioaktiver wirkstoffeInfo
- Publication number
- ATE277601T1 ATE277601T1 AT99922274T AT99922274T ATE277601T1 AT E277601 T1 ATE277601 T1 AT E277601T1 AT 99922274 T AT99922274 T AT 99922274T AT 99922274 T AT99922274 T AT 99922274T AT E277601 T1 ATE277601 T1 AT E277601T1
- Authority
- AT
- Austria
- Prior art keywords
- plg
- encapsulated
- encapsulation
- bioactive ingredients
- dna
- Prior art date
Links
- 230000000975 bioactive effect Effects 0.000 title 1
- 238000005538 encapsulation Methods 0.000 title 1
- 239000004615 ingredient Substances 0.000 title 1
- XEKOWRVHYACXOJ-UHFFFAOYSA-N Ethyl acetate Chemical compound CCOC(C)=O XEKOWRVHYACXOJ-UHFFFAOYSA-N 0.000 abstract 3
- 238000000034 method Methods 0.000 abstract 2
- 239000011859 microparticle Substances 0.000 abstract 2
- 239000012867 bioactive agent Substances 0.000 abstract 1
- 239000000839 emulsion Substances 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 239000002245 particle Substances 0.000 abstract 1
- 229920000642 polymer Polymers 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
- 238000013341 scale-up Methods 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
- A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Manufacturing Of Micro-Capsules (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
- Colloid Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9810236.1A GB9810236D0 (en) | 1998-05-13 | 1998-05-13 | Improvements relating to encapsulation of bioactive agents |
| PCT/GB1999/001449 WO1999058112A1 (en) | 1998-05-13 | 1999-05-07 | Improvements relating to encapsulation of bioactive agents |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE277601T1 true ATE277601T1 (de) | 2004-10-15 |
Family
ID=10831974
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT99922274T ATE277601T1 (de) | 1998-05-13 | 1999-05-07 | Verbesserungen bezüglich der verkapselung bioaktiver wirkstoffe |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US6309569B1 (de) |
| EP (1) | EP1077679B1 (de) |
| JP (2) | JP2002514590A (de) |
| AT (1) | ATE277601T1 (de) |
| AU (1) | AU762778B2 (de) |
| CA (1) | CA2331465C (de) |
| DE (1) | DE69920686T2 (de) |
| GB (1) | GB9810236D0 (de) |
| WO (1) | WO1999058112A1 (de) |
Families Citing this family (120)
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| US6270795B1 (en) | 1995-11-09 | 2001-08-07 | Microbiological Research Authority | Method of making microencapsulated DNA for vaccination and gene therapy |
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| ATE355856T1 (de) * | 1998-07-30 | 2007-03-15 | Point Biomedical Corp | Neuer wirkstoffträger für die gefriertrocknung von wässrigen suspensionen von mikropartikeln |
| WO2002003961A1 (en) * | 2000-07-07 | 2002-01-17 | Corixa Corporation | Microspheres and adjuvants for dna vaccine delivery |
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-
1998
- 1998-05-13 GB GBGB9810236.1A patent/GB9810236D0/en not_active Ceased
-
1999
- 1999-05-07 CA CA002331465A patent/CA2331465C/en not_active Expired - Lifetime
- 1999-05-07 AU AU39386/99A patent/AU762778B2/en not_active Expired
- 1999-05-07 DE DE69920686T patent/DE69920686T2/de not_active Expired - Lifetime
- 1999-05-07 JP JP2000547964A patent/JP2002514590A/ja active Pending
- 1999-05-07 WO PCT/GB1999/001449 patent/WO1999058112A1/en not_active Ceased
- 1999-05-07 EP EP99922274A patent/EP1077679B1/de not_active Expired - Lifetime
- 1999-05-07 AT AT99922274T patent/ATE277601T1/de not_active IP Right Cessation
- 1999-05-13 US US09/310,936 patent/US6309569B1/en not_active Expired - Lifetime
-
2010
- 2010-06-28 JP JP2010146974A patent/JP2010270121A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| US6309569B1 (en) | 2001-10-30 |
| DE69920686T2 (de) | 2006-02-23 |
| JP2002514590A (ja) | 2002-05-21 |
| CA2331465C (en) | 2008-08-26 |
| DE69920686D1 (de) | 2004-11-04 |
| AU3938699A (en) | 1999-11-29 |
| GB9810236D0 (en) | 1998-07-08 |
| EP1077679A1 (de) | 2001-02-28 |
| AU762778B2 (en) | 2003-07-03 |
| CA2331465A1 (en) | 1999-11-18 |
| WO1999058112A1 (en) | 1999-11-18 |
| JP2010270121A (ja) | 2010-12-02 |
| EP1077679B1 (de) | 2004-09-29 |
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| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |