ATE277922T1 - Verfahren zur herstellung von 10, 11methanodibenzosuberanderivaten - Google Patents

Verfahren zur herstellung von 10, 11methanodibenzosuberanderivaten

Info

Publication number
ATE277922T1
ATE277922T1 AT00935852T AT00935852T ATE277922T1 AT E277922 T1 ATE277922 T1 AT E277922T1 AT 00935852 T AT00935852 T AT 00935852T AT 00935852 T AT00935852 T AT 00935852T AT E277922 T1 ATE277922 T1 AT E277922T1
Authority
AT
Austria
Prior art keywords
producing
difluoromethanodibenzosuber
hydroxypropoxy
piperazin
quinoline
Prior art date
Application number
AT00935852T
Other languages
English (en)
Inventor
Bret Anthony Astleford
Charles Jackson Barnett
Michael Edward Kobierski
Thomas Michael Wilson
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Application granted granted Critical
Publication of ATE277922T1 publication Critical patent/ATE277922T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/06—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by halogen atoms or nitro radicals
    • C07D295/073—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by halogen atoms or nitro radicals with the ring nitrogen atoms and the substituents separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20—Oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Quinoline Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
AT00935852T 1999-06-03 2000-05-30 Verfahren zur herstellung von 10, 11methanodibenzosuberanderivaten ATE277922T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US13728499P 1999-06-03 1999-06-03
PCT/US2000/011863 WO2000075132A1 (en) 1999-06-03 2000-05-30 Process for preparing a 10,11-methanodibenzosuberane derivative

Publications (1)

Publication Number Publication Date
ATE277922T1 true ATE277922T1 (de) 2004-10-15

Family

ID=22476646

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00935852T ATE277922T1 (de) 1999-06-03 2000-05-30 Verfahren zur herstellung von 10, 11methanodibenzosuberanderivaten

Country Status (10)

Country Link
US (2) US6570016B1 (de)
EP (1) EP1198462B1 (de)
JP (1) JP2003501425A (de)
AT (1) ATE277922T1 (de)
AU (1) AU5125200A (de)
CA (1) CA2375283A1 (de)
DE (1) DE60014386T2 (de)
ES (1) ES2228534T3 (de)
PE (1) PE20010291A1 (de)
WO (1) WO2000075132A1 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6207392B1 (en) * 1997-11-25 2001-03-27 The Regents Of The University Of California Semiconductor nanocrystal probes for biological applications and process for making and using such probes
AU5125200A (en) * 1999-06-03 2000-12-28 Eli Lilly And Company Process for preparing a 10,11-methanodibenzosuberane derivative
DE60202944T2 (de) 2001-04-25 2006-03-23 Eli Lilly And Co., Indianapolis Neue salze und kristalline formen von (2r)-anti-5-3-(4-(10,11-difluoromethanodibenzosuber-5-yl)piperazin-1-yl)-2-hydroxypropoxy quinolin
EP1915466B1 (de) * 2005-08-19 2010-11-24 Nanosphere, Inc. Verfahren zur herstellung von hybridsubstraten mit dna und antikörpern sowie verwendungen davon

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE174913T1 (de) * 1992-07-31 1999-01-15 Bristol Myers Squibb Co Diphenyl oxazole-, thiazole- und imidazole- derivate als inhibitoren der wiederaufnahme des adenosins
US5643909A (en) * 1993-04-19 1997-07-01 Syntex (U.S.A.) Inc. 10,11-Methanodibenzosuberane derivatives
EP0775128A1 (de) * 1995-06-07 1997-05-28 Dade Chemistry Systems Inc. Verfahren zur herstellung von immunogenen und anderen arzneimittelkonjugaten
JP2000512997A (ja) * 1996-06-17 2000-10-03 イーライ・リリー・アンド・カンパニー 薬物耐性および多薬物耐性調節物質
EP0844244A1 (de) * 1996-11-22 1998-05-27 Eli Lilly And Company Drogenresistente und multidrogenresistente Modulatoren
TWI267511B (en) * 1999-06-03 2006-12-01 Lilly Co Eli Process for preparing 10,11-methanobenzosuberane derivatives
AU5125200A (en) * 1999-06-03 2000-12-28 Eli Lilly And Company Process for preparing a 10,11-methanodibenzosuberane derivative

Also Published As

Publication number Publication date
PE20010291A1 (es) 2001-03-07
CA2375283A1 (en) 2000-12-14
EP1198462B1 (de) 2004-09-29
US6570016B1 (en) 2003-05-27
DE60014386T2 (de) 2005-10-13
ES2228534T3 (es) 2005-04-16
DE60014386D1 (de) 2004-11-04
WO2000075132A1 (en) 2000-12-14
AU5125200A (en) 2000-12-28
US6624304B1 (en) 2003-09-23
JP2003501425A (ja) 2003-01-14
EP1198462A1 (de) 2002-04-24

Similar Documents

Publication Publication Date Title
DE60234952D1 (de) VERFAHREN ZUR HERSTELLUNG VON HEXAHYDROFUROc2,3-BÜFURAN-3-OL
DE69932609D1 (de) Verfahren zur herstellung von 1-chloro-1,1,3,3,3-pentafluorpropan
BR0005636A (pt) Método para a produção de 4-carboxiamino-1,2,3,4-tetrahidroquinolina 2-substituìda
DE60124289D1 (de) Verfahren zur herstellung von 21-hydroxy-6,19-oxidoprogesteron (21oh-6op)
DE60022996D1 (de) Verfahren zur herstellung von poly(1,4-cyclohexandicarboxylat)
ATE270275T1 (de) Verfahren zur herstellung von 2-aryl-3-aryl-5- halogen-pyridinen, verwendbar als cox-2 inhibitoren
ATE506351T1 (de) Verfahren zur herstellung von 10,11-dihydro-10- oxo-5h-dibenzoäb,füazepin-5-carboxamid
ATE253037T1 (de) Verfahren zur racematspaltung von tramadol
DE60001599D1 (de) Verfahren zur Herstellung von cis-1-2-[4-(6-Methoxy-2-phenyl-1,2,3,4-tetrahydronaphthalen-1-yl)phenoxy]ethyl-pyrrolidin
ATE378307T1 (de) Verfahren zur gewinnung von cetamin-enantiomeren.
ATE323677T1 (de) Verfahren zur herstellung von 4-amino-2,5- bisheterocyclylchinazolinen
DE60014386D1 (de) Verfahren zur herstellung von 10,11methanodibenzosuberanderivaten
ATE374757T1 (de) Verfahren zur herstellung von (1,4,5)- oxadiazepinderivaten
ATE275149T1 (de) Verfahren zur herstellung von taxanderivaten
ATE310734T1 (de) Verfahren zur herstellung von n-substituierten 2, 6-dialkylmorpholinen
ATE387425T1 (de) Verfahren zur herstellung von bicalutamid
ATA21152000A (de) Verfahren zur herstellung von wolframcarbid
ATE244706T1 (de) Enantiomere von mercaptolactonen und verfahren zu ihrer herstellung
DE50103009D1 (de) Verfahren zur herstellung von 2-alkyl-3-chlorphenolen
ATE267820T1 (de) Prozess zur herstellung von paclitaxel
DE69923163D1 (de) Verfahren zur herstellung von 1,2,4-butantriol
DE10082646D2 (de) Verfahren zur Herstellung bzw. Gewinnung von 2,6-Dichlortoluol
ATE281437T1 (de) Verfahren zur herstellung von 3-substituierte 1,5-diarylpyrozole
ATE458723T1 (de) Verfahren zur herstellung von 4,6-dichlor-5- fluorpyrimidin
DE69918337D1 (de) Verfahren zur herstellung von 2,6-dialkylnaphthalen

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties